• Title/Summary/Keyword: hand evaluation

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Evaluation of circulating IGF-I and IGFBP-3 as biomarkers for tumors in dogs

  • Song, Doo-Won;Ro, Woong-Bin;Sur, Jung-Hyang;Seung, Byung-Joon;Kang, Hyun-Min;Kim, Jong-Won;Park, See-Hyoung;Park, Hee-Myung
    • Journal of Veterinary Science
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    • v.22 no.6
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    • pp.77.1-77.10
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    • 2021
  • Background: Serum-based parameters are considered non-invasive biomarkers for cancer detection. In human studies, insulin-like growth factor-I and II (IGF-I and IGF-II) and insulin-like growth factor binding protein-3 (IGFBP-3) are useful as diagnostic or prognostic markers and potential therapeutic targets. Objectives: This study examined the diagnostic utility of circulating IGF-I, IGF-II, and IGFBP-3 levels in healthy dogs and dogs with tumors. Methods: The serum concentrations of these biomarkers in 86 dogs with tumors were compared with those in 30 healthy dogs using an enzyme-linked immunosorbent assay (ELISA). Results: The ELISA results showed no difference between healthy dogs and dogs with tumors in the serum IGF-II concentrations. On the other hand, there was a significant difference in the circulating IGF-I and IGFBP-3 levels between healthy dogs and dogs with tumors. The concentrations of serum IGF-I (median [interquartile range], 103.4 [59.5-175] ng/mL) in dogs with epithelial tumors were higher than those (58.4 ng/mL [43.5-79.9]) in healthy dogs. Thus, the concentrations of serum IGFBP-3 (43.4 ng/mL [33.2-57.2]) in dogs with malignant mesenchymal tumors were lower than those (60.8 ng/mL [47.6-70.5]) in healthy dogs. Conclusions: The serum IGF-I and IGFBP-3 levels can be used as diagnostic biomarkers in dogs with tumors.

An Analysis of the Research Topics of the Academic Papers Published in the Journal of Korean Society of Archives and Records Management: From 2001 to 2017 (『한국기록관리학회지』 논문의 연구 주제 분석 - 2001년부터 2017년까지 -)

  • Kim, Heesop;Kang, Bora
    • Journal of Korean Society of Archives and Records Management
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    • v.18 no.4
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    • pp.183-204
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    • 2018
  • The main purpose of this study was to investigate the research topics of the Journal of Korean Society of Archives and Records Management, which is one of the main academic journals of archival research in Korea. To achieve this objective, a total of 875 author-assigned Korean keywords were collected from the 390 papers published from the first issue (i.e., 2001) to the current issue (i.e., 2017) in the target journal. The collected keywords were analyzed using NetMiner V.4 to discover their frequency, degree centrality, and betweenness centrality. Results showed that "Archival Information Services," "Electronic Records," "Historical Archives," "Archivists," and "National Archives of Korea" showed the most frequently conducted research topics; whereas "Archival Information Services," "Electronic Records," "Evaluation," "Locality Archives," and "Retrieval System" were the most influencing research topics. On the other hand, "Archival Information Services," "Archivists," "Electronic Records," "Archive," and "Metadata" showed the most widely intervening research topics in this research.

Network Analysis between Uncertainty Words based on Word2Vec and WordNet (Word2Vec과 WordNet 기반 불확실성 단어 간의 네트워크 분석에 관한 연구)

  • Heo, Go Eun
    • Journal of the Korean Society for Library and Information Science
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    • v.53 no.3
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    • pp.247-271
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    • 2019
  • Uncertainty in scientific knowledge means an uncertain state where propositions are neither true or false at present. The existing studies have analyzed the propositions written in the academic literature, and have conducted the performance evaluation based on the rule based and machine learning based approaches by using the corpus. Although they recognized that the importance of word construction, there are insufficient attempts to expand the word by analyzing the meaning of uncertainty words. On the other hand, studies for analyzing the structure of networks by using bibliometrics and text mining techniques are widely used as methods for understanding intellectual structure and relationship in various disciplines. Therefore, in this study, semantic relations were analyzed by applying Word2Vec to existing uncertainty words. In addition, WordNet, which is an English vocabulary database and thesaurus, was applied to perform a network analysis based on hypernyms, hyponyms, and synonyms relations linked to uncertainty words. The semantic and lexical relationships of uncertainty words were structurally identified. As a result, we identified the possibility of automatically expanding uncertainty words.

Effects of Pressurization on Finger's Blood Velocity of Tendon and Muscle Areas in Forearm of 20's male (20대 남성의 아래팔 손목 건영역과 근육영역 가압이 손가락 혈류속도에 미치는 효과)

  • Kim, Nam Yim;Hong, Kyunghi
    • Fashion & Textile Research Journal
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    • v.21 no.4
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    • pp.488-496
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    • 2019
  • This study investigated if the proper pressure level on the wrist tendon area and muscle area of the lower arm are within the same range by examining the responses of blood flow and subjective evaluation. Subjects consisted of 18 males in their 20s, and the experimental bands were custom-made by applying size measurements of each subject. In the experiment, a total of 5 steps were selected by reducing 10 (Step 1) to 50 (Step 5)% from the original body size in the circumferential direction. Blood flow was measured with a sensor attached to the tip of the finger inside the right hand while sitting in a chair for 15 minutes. Blood velocity began to increase (0.82 kPa) when the wrist circumference around tendon area was reduced by 20% (Step 2) and reached its maximum (1.72 kPa) at Step 4. However, the preferred subjective pressure was 1.36 kPa, which was less than the maximum pressure value of 1.72 kPa for Step 4. Blood velocity began to increase when pressure on the muscle area was 1.38 kPa and reached its maximum at 2.16 kPa; however, the most preferred clothing pressure was 1.71 kPa. The results of this study showed that the appropriate pressure level was higher in the muscle area than in the wrist tendon of the lower arm and indicated that graduated compression is favorable.

Camera and LiDAR Sensor Fusion for Improving Object Detection (카메라와 라이다의 객체 검출 성능 향상을 위한 Sensor Fusion)

  • Lee, Jongseo;Kim, Mangyu;Kim, Hakil
    • Journal of Broadcast Engineering
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    • v.24 no.4
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    • pp.580-591
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    • 2019
  • This paper focuses on to improving object detection performance using the camera and LiDAR on autonomous vehicle platforms by fusing detected objects from individual sensors through a late fusion approach. In the case of object detection using camera sensor, YOLOv3 model was employed as a one-stage detection process. Furthermore, the distance estimation of the detected objects is based on the formulations of Perspective matrix. On the other hand, the object detection using LiDAR is based on K-means clustering method. The camera and LiDAR calibration was carried out by PnP-Ransac in order to calculate the rotation and translation matrix between two sensors. For Sensor fusion, intersection over union(IoU) on the image plane with respective to the distance and angle on world coordinate were estimated. Additionally, all the three attributes i.e; IoU, distance and angle were fused using logistic regression. The performance evaluation in the sensor fusion scenario has shown an effective 5% improvement in object detection performance compared to the usage of single sensor.

Experimental evaluation of an inertial mass damper and its analytical model for cable vibration mitigation

  • Lu, Lei;Fermandois, Gaston A.;Lu, Xilin;Spencer, Billie F. Jr.;Duan, Yuan-Feng;Zhou, Ying
    • Smart Structures and Systems
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    • v.23 no.6
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    • pp.589-613
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    • 2019
  • Cables are prone to vibration due to their low inherent damping characteristics. Recently, negative stiffness dampers have gained attentions, because of their promising energy dissipation ability. The viscous inertial mass damper (termed as VIMD hereinafter) can be viewed as one realization of the inerter. It is formed by paralleling an inertial mass part with a common energy dissipation element (e.g., viscous element) and able to provide pseudo-negative stiffness properties to flexible systems such as cables. A previous study examined the potential of IMD to enhance the damping of stay cables. Because there are already models for common energy dissipation elements, the key to establish a general model for IMD is to propose an analytical model of the rotary mass component. In this paper, the characteristics of the rotary mass and the proposed analytical model have been evaluated by the numerical and experimental tests. First, a series of harmonic tests are conducted to show the performance and properties of the IMD only having the rotary mass. Then, the mechanism of nonlinearities is analyzed, and an analytical model is introduced and validated by comparing with the experimental data. Finally, a real-time hybrid simulation test is conducted with a physical IMD specimen and cable numerical substructure under distributed sinusoidal excitation. The results show that the chosen model of the rotary mass part can provide better estimation on the damper's performance, and it is better to use it to form a general analytical model of IMD. On the other hand, the simplified damper model is accurate for the preliminary simulation of the cable responses.

A Study on the Influence of Mobile Music Application Users' Social Experience on Purchasing Intention - The Mediating Effect of Brand Attachment

  • Li, Jingrong
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.7
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    • pp.53-60
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    • 2019
  • With the gradual in-depth use of social elements, music social networking has attracted more and more attention and discussion in the industry. Therefore, starting from the user experience theory and purchase intention theory, this paper explores the mechanism of user social experience and purchase intention in mobile music applications, and adds the mediating role of brand attachment on the basis of literature research. Based on previous studies on user experience measurement of social network and evaluation report of mobile music applications in the industry, and combined with in-depth interviews of users, whether the user experience of mobile music applications, which pays more and more attention to social elements, has an impact on purchase intention or not? What specific social experience can help form purchase intention? Are mediating variables at work? In practice, a total of 398 formal questionnaires were collected to obtain first-hand data. Later, reliability analysis, factor analysis and structural equation model test were carried out successively to verify the hypothesis. According to the results of empirical research, firstly, content experience, atmosphere experience and interactive experience in users' social experience of mobile music applications have a significant impact on brand attachment, secondly, atmosphere experience has a significant impact on purchase intention, and thirdly, brand attachment has a significant impact on users' purchase intention. Fourthly, brand attachment plays an intermediary role in the relationship between users' atmosphere experience and content experience and purchase intention. Based on the above research conclusions, the author puts forward corresponding marketing strategy Suggestions, which have certain guiding significance for mobile music applications to improve users' purchase intention, and have certain reference significance for the development of mobile music applications and the expansion of business model.

Flexural Strength and Durability Evaluation by Freezing and Thawing Test of Repaired Reinforced Concrete Beams (보수보강을 실시한 철근콘크리트 보의 동결융해시험을 통한 휨강도 및 내구성 평가)

  • Lee, Chang-Hyun;Eo, Seok-Hong
    • The Journal of the Korea Contents Association
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    • v.18 no.11
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    • pp.455-461
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    • 2018
  • This paper presents experimental investigations about flexural strength and durability of reinforced concrete beams repaired using ductile fiber reinforced cementitious composite (DFRCC) and carbon fiber sheet through freezing and thawing test. Total 14 RC beams of $100{\times}100{\times}400mm$ size were tested by 3-point bending and freezing and thawing test by KS F 2456. The beams were reinforced using 3D10 steels on both the tensile and compressive sides, and repaired on 3 sides expect on top cycle. Test results showed that the beams repaired using fiber carbon sheet revealed about 15% higher values of flexural strength compared than the cases of DFRCC motar. On the other hand, the results did not showed meaningful differences in the aspect of durability. For further research, consideration of the steel interference effect and real old specimens such as taken from real deteriorated structures are needed to be tested after repairing with DFRCC and carbon fiber sheet.

Relationship between Crack Width and Gas Diffusion Coefficient of Cracked Acrylic Specimens (균열 아크릴 시편의 기체 확산계수와 균열폭의 관계)

  • Lee, Do-Keun;Lim, Min-Hyuk;Shin, Kyung-Jun
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.6 no.4
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    • pp.245-251
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    • 2018
  • Recently, as the importance of structural maintenance has been increased, studies on self - healing concrete technology are being actively carried out. On the other hand, test for evaluating the self-healing performance is not standardized yet. Although visual test is used as a basic method for measuring crack widths, it is difficult to observe the crack width inside the specimen, and there is a disadvantage that only the local measurement of the surface can be measured due to the inhomogeneous cracking characteristics. Although permeability test has been widely used as an indirect method for measuring crack width, there is a problem due to the viscosity of water, and also a possibility that the internal material of the specimen may be eluted during the test. In this study, we propose a crack width evaluation method using gas diffusion characteristics. Idealized straight cracks were fabricated by acrylic and the diffusion coefficients of specimens were analyzed with respect to crack width and thickness. The experimental results show that the crack width and the diffusion coefficient are in a linear relationship and that the thickness and diffusion coefficient are inversely related.

An Operation Status Analysis of Library Building using BEMS Data; Energy Performance Evaluation on Initial Stage of Completion (BEMS 데이터를 활용한 도서관 건물의 운전현황 분석 -준공 초기단계의 건물 에너지 성능 평가)

  • Park, Seong-cheol;Ha, Ju-wan;Kim, Hwan-yong;Song, Young-hak
    • Journal of Korean Institute of Architectural Sustainable Environment and Building Systems
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    • v.12 no.6
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    • pp.669-679
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    • 2018
  • Energy consumption savings in buildings should be reviewed in diverse areas such as air conditioning system and lighting responsible for cooling and heating, and energy management systems such as BAS (Building Automation System) and BEMS (Building Energy Management System) are introduced to improve energy consumption efficiency and to promote economic control of related facilities by integrated management of energy generated and consumption in buildings. The measured building of this study uses regenerative geothermal system. Measured values of heat pump and system COP were 4.7 and 4.2 respectively, and they were found to be higher 11.9% and 23.5% than rated values. As a result of analyzing the air conditioning and lighting energy from the first floor to the fourth floor performing the air conditioning, the second and third floors, which have a high frequency of use, are compared with the first and fourth floors 50% higher energy consumption ratio. On the other hand, the general heat storage system uses the nighttime power of the previous day to store heat and use it the next day. The total number of days of abnormal operation during the summer season is 61 days. The electricity cost corresponding to the abnormal operation is 1,840,641 KRW, and the normal operation using the nighttime power is 1,363,561 KRW, which is difference of 477,080 KRW, 35% increase in cost. We will utilize it as the main data of BEMS through analysis of winter operation characteristics as well as summer operation characteristics.