• 한국약용작물학회지
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• 제20권2호
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• pp.108-116
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• 2012

In this study, to develop hair growth agents using natural products which has excellent ability to promote hair growth effect and fewer side effect, animal experiment and clinical trials was performed to evaluate hair growth promotion effect of herbal product containing $Rosa$ $mutiflora$ roots extracts as a main component (RMHP). 4-week-old male C57BL/6 mice were removed the dorsal hair using thioglycolate, and applied 15% EtOH solution as a negative control, 5% minoxidil as a positive control and RMHP to dorsal skin. In the results of macroscopy and photo-interpretation, RMHP group recorded 100% (+++++) of hair growth was proved to significantly stimulate hair growth against 80% (++++) negative control group. 37 patients were treated with RMHP and evaluated the therapeutic effect at 16 weeks. Hair density was significantly increased at 16 weeks after applying RMHP ($125.0{\pm}4.9\;FU/cm^2$) compared to before treatment ($104.3{\pm}4.7\;FU/cm^2$, p < 0.05), and hair thickness were also significantly increased ($0.066{\pm}0.003$ mm) than before treatment ($0.055{\pm}0.002$ mm, p < 0.05). The result of clinical photo-interpretation using 7-point rating scale assessment, after 16 weeks clinical symptoms were evaluated to significantly improve with $1.23{\pm}0.05$ (p < 0.05). Therefore, the results of this study were observed that RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients.

• 패션비즈니스
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• 제5권3호
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• pp.73-84
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• 2001

The purpose of this study is to apply fundamental data of impression formation research by analysing and observing the various facial image that can be effected from hair style as well as be helpful for choosing suitable hair style for T.P.O in modern society. This study targeted 305 college women in Daegu and Gyung-book area. Hair Style Image Scale(HSIS)was used the scale of seven point modified the S-D(Semantic Differential) method. The analysis of impression formation effect of hair style using SPSS WIN package have completed from the principal component analysis by Varimax perpendicular rotation method and ANOVA was used to recognize the difference in impression formation according to hair style change. In the case of statistical difference was appeared, LSD post-verification was applied for that. The conclusions of this study is as followed ; 1. The factors of impression formation effected by hair style were classified as goodwill factor, refinement factor, elegance factor and individuality factor. 2. In terms of goodwill factor, long hair style showed highest level and short cut hair, bobbed hair in an order. In refinement factor, there was no difference between short cut hair and bobbed hair and both of them was higher than long hair. In elegance factor, long hair was highest and bobbed hair was lowest. In individuality factor, short cut hair and bobbed hair higher than long hair and no difference between short cut hair and bobbed hair.

• 대한가정학회지
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• 제44권4호
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• pp.39-47
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• 2006

This study considers the Gagye(Added Hair) style shown in ancient Goguryeo Murals and examines its values and significance through an in-depth study on the relevance to the style of China. In Gagye style, the Korean Hwan-gye(Round-rolled Hair) hair type was different from that of China in letting the hair down and using accessories. The Korean Sseu-gye(Covered Hair) hair type features textile-made and Bokbal (Covered hair) styles. The Korean Go-gye(Highly-rolled up Hair) hair type was different from that of China in style and volume. The Korean Da-gye(Multi-laid Hair) hair type was different from that of China in component pattern in that the Korean Da-gye type was composed of two or three gyes. Eoneun meori (Braided & Coiled Hair) features the unique Goguryeo pattern in which "Che" was placed on the head and the hair was braided down on the sides of the face. Therefore, the Gagye style of Goguryeo Murals was localized and developed through cultural interchange between Goguryeo and China. It also features its own values and significance in Korea's clothing history.

• 한국의류산업학회지
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• 제7권1호
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• pp.96-100
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• 2005

The bleaching is one of the worst factors which leads to the damage of the human hair. The cuticle of the human hair is injured by the alkali that is one of the chief ingredients of a bleaching agent. The alkali component of the bleaching solution chemically reacts with human hair, reducing the tenacity and dissolving the cuticle layer. The purpose of this study is to examine the effects of bleaching time and temperature on the physical properties and morphology. The results were as follows. 1. The stress-strain curves for human hair indicated the three distinct regions, such as Hookean region, Yield region and post-Yield region. The tenacity of hair is reduced gradually with an increase of bleaching time. Under these same conditions, elongation of the hair increased. 2. The greatest drop in tenacity for hair occured between $40^{\circ}C$ and $60^{\circ}C$ of bleaching temperature. 3. Compared with the virgin hair, bleached hair showed a slower rate of weight reduction in the TGA thermogram. The rate decreased gradually as the bleaching time and temperature increased. 4. As the bleaching conditions reached time and temperature extremes, the human hair cuticle became more damaged. The cuticle layers seemed to have dissolved, as seen in the SEM photographs.

• Biomolecules & Therapeutics
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• 제29권6호
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• pp.643-649
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• 2021

Literature has revealed that the delta opioid receptor (DOR) exhibited diverse pharmacological effects on neuron and skin. In the present study, we have investigated whether the activation of DOR has hair-growth promotion effects. Compared with other opioid receptor, DOR was highly expressed in epidermal component of hair follicle in human and rodents. The expression of DOR was high in the anagen phase, but it was low in the catagen and telogen phases during mouse hair cycle. Topical application of UFP-512, a specific DOR agonist, significantly accelerated the induction of the anagen in C₃H mice. Topical application of UFP-512 also increased the hair length in hair organ cultures and promoted the proliferation and the migration of outer root sheath (ORS) cells. Similarly, pharmacological inhibition of DOR by naltrindole significantly inhibited the anagen transition process and decreased hair length in hair organ cultures. Thus, we further examined whether Wnt/β-catenin pathway was related to the effects of DOR on hair growth. We found that Wnt/β-catenin pathway was activated by UFP-512 and siRNA for β-catenin attenuated the UFP-512 induced proliferation and migration of ORS cells. Collectively, result established that DOR was involved in hair cycle regulation, and that DOR agonists such as UFP-512 should be developed for novel hair-loss treatment.

• 농업과학연구
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• 제47권2호
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• pp.305-313
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• 2020

Root hair development has the potential to increase crop yields and at the same time to decrease fertilizer use, which will be required in the next 30 years to meet the demand for crop-derived commodities in a world with decreasing available natural resources. Root hair defective six (RHD6) encoding a basic helix-loop-helix transcription factor, is associated with root hair differentiation, and its roles are root hair initiation and elongation. Grass plants, rice and Brachypodium have been used as model plants to study the gene function of the root hair defective six like (RSL) subfamily which is orthologous to AtRHD6. The RSL subfamily has an identical gene function with AtRHD6 which is involved with root hair differentiation as well. Plants with longer root hairs within a species should have an improved Pi uptake efficiency; therefore, we would expect that a plant with a high Pi uptake could contribute to increasing the plant yield. We achieved increased root hair length by manipulating the RSL subfamily genes. It is expected that in these transgenic plants, the long root hairs would be sufficient to improve the Pi uptake and hence improve biomass and yield component (tiller, spikelet number, and spikelet weight) of the plant. Here, we demonstrate that Brachypodium transgenic plants overexpressing the BdRSL subfamily genes have an improved biomass and grain yield. The result of this study could be applied to important crop plants like rice.

• Toxicological Research
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• 제30권4호
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• pp.297-304
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• 2014

Peppermint (Mentha piperita) is a plant native to Europe and has been widely used as a carminative and gastric stimulant worldwide. This plant also has been used in cosmetic formulations as a fragrance component and skin conditioning agent. This study investigated the effect of peppermint oil on hair growth in C57BL/6 mice. The animals were randomized into 4 groups based on different topical applications: saline (SA), jojoba oil (JO), 3% minoxidil (MXD), and 3% peppermint oil (PEO). The hair growth effects of the 4-week topical applications were evaluated in terms of hair growth, histological analysis, enzymatic activity of alkaline phosphatase (ALP), and gene expression of insulin-like growth factor-1 (IGF-1), known bio-markers for the enhanced hair growth. Of the 4 experimental groups, PEO group showed the most prominent hair growth effects; a significant increase in dermal thickness, follicle number, and follicle depth. ALP activity and IGF-1 expression also significantly increased in PEO group. Body weight gain and food efficiency were not significantly different between groups. These results suggest that PEO induces a rapid anagen stage and could be used for a practical agent for hair growth without change of body weight gain and food efficiency.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVI)
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• pp.222-222
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• 2005

• 융합정보논문지
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• 제11권10호
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• pp.270-276
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• 2021

본 연구는 홈케어 헤어트리트먼트 특성 및 사용 빈도에 따라 퍼머넌트 웨이브 시술시 모발에 미치는 영향을 알아보고자 수행하였다. 시중에 유통되는 헤어트리트먼트를 양이온계면활성제, 실리콘 오일로 구분하였다. 사용빈도에 따라 제품별 5회, 10회, 20회 다르게 헤어트리트먼트를 처리한 후 헤어 퍼머넌트 웨이브를 시술하였다. 실험 방법으로 모발의 굵기, 인장강도, SEM을 이용한 모표피 관찰, EDS를 이용한 모발 구성 원소 분석을 하였다. 실험 결과 천연유래성분이 주성분이며 양이온계면활성 및 실리콘 오일이 미첨가된 제품군이 모발 보호 효과가 높게 측정되었다. 이에 천연유래성분을 이용한 제품군이 더욱 연구 개발되어야 하며 자극적 화학 성분이 첨가된 제품은 사용 방법 및 빈도에 대한 연구가 진행 되어야 할 것으로 사료된다.

• 융합정보논문지
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• 제11권11호
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• pp.288-295
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• 2021

본 연구는 마스크팩 유효성분을 흡착시킨 엔드 페이퍼를 퍼머넌트 웨이브 시술시 모발에 미치는 영향을 알아보고자 수행하였다. 시중에 판매되는 마스크팩 중 청귤, 콜라겐, 어성초 유효성분을 함유한 마스크팩을 구입하여 엔드 페이퍼에 흡착시켜 퍼머넌트 웨이브를 시술하였다. 실험 방법으로 모발 굵기, 모발 보습력, 인장강도, SEM을 이용한 모표피 관찰, EDS를 이용한 모발 구성 원소 분석을 하였다. 실험 결과 어성초 유효성분을 엔드 페이퍼에 처리한 실험군이 모발 굵기, 인장강도, 모표피 관찰, 모발 구성 원소 분석 결과 모발 보호효과가 있는 것으로 확인되었다. 또한 청귤 유효성분을 엔드 페이퍼에 처리한 실험군은 모발 보습력 실험 결과에서 비교적 많은 수분을 함유하고 있는 것으로 확인되었다. 유효성분들이 함유된 기초화장품 제품들을 활용하여 모발화장품으로 개발하여 활용하고, 산업현장에서 화학시술 시에 적용할 수 있도록 다양한 재료와 도구들에 대한 개발과 연구가 진행되기를 바라는 바이다.