• Korean Journal of Medicinal Crop Science
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• v.20 no.2
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• pp.108-116
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• 2012

In this study, to develop hair growth agents using natural products which has excellent ability to promote hair growth effect and fewer side effect, animal experiment and clinical trials was performed to evaluate hair growth promotion effect of herbal product containing $Rosa$ $mutiflora$ roots extracts as a main component (RMHP). 4-week-old male C57BL/6 mice were removed the dorsal hair using thioglycolate, and applied 15% EtOH solution as a negative control, 5% minoxidil as a positive control and RMHP to dorsal skin. In the results of macroscopy and photo-interpretation, RMHP group recorded 100% (+++++) of hair growth was proved to significantly stimulate hair growth against 80% (++++) negative control group. 37 patients were treated with RMHP and evaluated the therapeutic effect at 16 weeks. Hair density was significantly increased at 16 weeks after applying RMHP ($125.0{\pm}4.9\;FU/cm^2$) compared to before treatment ($104.3{\pm}4.7\;FU/cm^2$, p < 0.05), and hair thickness were also significantly increased ($0.066{\pm}0.003$ mm) than before treatment ($0.055{\pm}0.002$ mm, p < 0.05). The result of clinical photo-interpretation using 7-point rating scale assessment, after 16 weeks clinical symptoms were evaluated to significantly improve with $1.23{\pm}0.05$ (p < 0.05). Therefore, the results of this study were observed that RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients.

• Journal of Fashion Business
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• v.5 no.3
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• pp.73-84
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• 2001

The purpose of this study is to apply fundamental data of impression formation research by analysing and observing the various facial image that can be effected from hair style as well as be helpful for choosing suitable hair style for T.P.O in modern society. This study targeted 305 college women in Daegu and Gyung-book area. Hair Style Image Scale(HSIS)was used the scale of seven point modified the S-D(Semantic Differential) method. The analysis of impression formation effect of hair style using SPSS WIN package have completed from the principal component analysis by Varimax perpendicular rotation method and ANOVA was used to recognize the difference in impression formation according to hair style change. In the case of statistical difference was appeared, LSD post-verification was applied for that. The conclusions of this study is as followed ; 1. The factors of impression formation effected by hair style were classified as goodwill factor, refinement factor, elegance factor and individuality factor. 2. In terms of goodwill factor, long hair style showed highest level and short cut hair, bobbed hair in an order. In refinement factor, there was no difference between short cut hair and bobbed hair and both of them was higher than long hair. In elegance factor, long hair was highest and bobbed hair was lowest. In individuality factor, short cut hair and bobbed hair higher than long hair and no difference between short cut hair and bobbed hair.

• Journal of the Korean Home Economics Association
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• v.44 no.4 s.218
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• pp.39-47
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• 2006

This study considers the Gagye(Added Hair) style shown in ancient Goguryeo Murals and examines its values and significance through an in-depth study on the relevance to the style of China. In Gagye style, the Korean Hwan-gye(Round-rolled Hair) hair type was different from that of China in letting the hair down and using accessories. The Korean Sseu-gye(Covered Hair) hair type features textile-made and Bokbal (Covered hair) styles. The Korean Go-gye(Highly-rolled up Hair) hair type was different from that of China in style and volume. The Korean Da-gye(Multi-laid Hair) hair type was different from that of China in component pattern in that the Korean Da-gye type was composed of two or three gyes. Eoneun meori (Braided & Coiled Hair) features the unique Goguryeo pattern in which "Che" was placed on the head and the hair was braided down on the sides of the face. Therefore, the Gagye style of Goguryeo Murals was localized and developed through cultural interchange between Goguryeo and China. It also features its own values and significance in Korea's clothing history.

• The Korean Fashion and Textile Research Journal
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• v.7 no.1
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• pp.96-100
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• 2005

The bleaching is one of the worst factors which leads to the damage of the human hair. The cuticle of the human hair is injured by the alkali that is one of the chief ingredients of a bleaching agent. The alkali component of the bleaching solution chemically reacts with human hair, reducing the tenacity and dissolving the cuticle layer. The purpose of this study is to examine the effects of bleaching time and temperature on the physical properties and morphology. The results were as follows. 1. The stress-strain curves for human hair indicated the three distinct regions, such as Hookean region, Yield region and post-Yield region. The tenacity of hair is reduced gradually with an increase of bleaching time. Under these same conditions, elongation of the hair increased. 2. The greatest drop in tenacity for hair occured between $40^{\circ}C$ and $60^{\circ}C$ of bleaching temperature. 3. Compared with the virgin hair, bleached hair showed a slower rate of weight reduction in the TGA thermogram. The rate decreased gradually as the bleaching time and temperature increased. 4. As the bleaching conditions reached time and temperature extremes, the human hair cuticle became more damaged. The cuticle layers seemed to have dissolved, as seen in the SEM photographs.

• Biomolecules & Therapeutics
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• v.29 no.6
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• pp.643-649
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• 2021

Literature has revealed that the delta opioid receptor (DOR) exhibited diverse pharmacological effects on neuron and skin. In the present study, we have investigated whether the activation of DOR has hair-growth promotion effects. Compared with other opioid receptor, DOR was highly expressed in epidermal component of hair follicle in human and rodents. The expression of DOR was high in the anagen phase, but it was low in the catagen and telogen phases during mouse hair cycle. Topical application of UFP-512, a specific DOR agonist, significantly accelerated the induction of the anagen in C₃H mice. Topical application of UFP-512 also increased the hair length in hair organ cultures and promoted the proliferation and the migration of outer root sheath (ORS) cells. Similarly, pharmacological inhibition of DOR by naltrindole significantly inhibited the anagen transition process and decreased hair length in hair organ cultures. Thus, we further examined whether Wnt/β-catenin pathway was related to the effects of DOR on hair growth. We found that Wnt/β-catenin pathway was activated by UFP-512 and siRNA for β-catenin attenuated the UFP-512 induced proliferation and migration of ORS cells. Collectively, result established that DOR was involved in hair cycle regulation, and that DOR agonists such as UFP-512 should be developed for novel hair-loss treatment.

• Korean Journal of Agricultural Science
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• v.47 no.2
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• pp.305-313
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• 2020

Root hair development has the potential to increase crop yields and at the same time to decrease fertilizer use, which will be required in the next 30 years to meet the demand for crop-derived commodities in a world with decreasing available natural resources. Root hair defective six (RHD6) encoding a basic helix-loop-helix transcription factor, is associated with root hair differentiation, and its roles are root hair initiation and elongation. Grass plants, rice and Brachypodium have been used as model plants to study the gene function of the root hair defective six like (RSL) subfamily which is orthologous to AtRHD6. The RSL subfamily has an identical gene function with AtRHD6 which is involved with root hair differentiation as well. Plants with longer root hairs within a species should have an improved Pi uptake efficiency; therefore, we would expect that a plant with a high Pi uptake could contribute to increasing the plant yield. We achieved increased root hair length by manipulating the RSL subfamily genes. It is expected that in these transgenic plants, the long root hairs would be sufficient to improve the Pi uptake and hence improve biomass and yield component (tiller, spikelet number, and spikelet weight) of the plant. Here, we demonstrate that Brachypodium transgenic plants overexpressing the BdRSL subfamily genes have an improved biomass and grain yield. The result of this study could be applied to important crop plants like rice.

• Toxicological Research
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• v.30 no.4
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• pp.297-304
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• 2014

Peppermint (Mentha piperita) is a plant native to Europe and has been widely used as a carminative and gastric stimulant worldwide. This plant also has been used in cosmetic formulations as a fragrance component and skin conditioning agent. This study investigated the effect of peppermint oil on hair growth in C57BL/6 mice. The animals were randomized into 4 groups based on different topical applications: saline (SA), jojoba oil (JO), 3% minoxidil (MXD), and 3% peppermint oil (PEO). The hair growth effects of the 4-week topical applications were evaluated in terms of hair growth, histological analysis, enzymatic activity of alkaline phosphatase (ALP), and gene expression of insulin-like growth factor-1 (IGF-1), known bio-markers for the enhanced hair growth. Of the 4 experimental groups, PEO group showed the most prominent hair growth effects; a significant increase in dermal thickness, follicle number, and follicle depth. ALP activity and IGF-1 expression also significantly increased in PEO group. Body weight gain and food efficiency were not significantly different between groups. These results suggest that PEO induces a rapid anagen stage and could be used for a practical agent for hair growth without change of body weight gain and food efficiency.

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.222-222
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• 2005

• Journal of Convergence for Information Technology
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• v.11 no.10
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• pp.270-276
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• 2021

The purpose of this study was to investigate the effects of home care hair treatment characteristics and frequency on hair during permanent wave treatment. The hair treatments distributed on the market were classified into cationic surfactants and silicone oil. Hair treatment was performed 5 times, 10 times, 20 times differently according to the frequency of use, and hair permanent wave was performed. The hair thickness, tensile strength, epidermal observation using SEM, and hair component analysis using EDS were performed as experimental methods. The results of the experiment showed that the natural-derived ingredient was the main ingredient, and the cationic surface activity and silicon oil-free product group had high hair protection effect. Therefore, the product group using natural ingredients should be further researched and developed, and the study on the method and frequency of use of products with irritant chemical ingredients should be conducted.

• Journal of Convergence for Information Technology
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• v.11 no.11
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• pp.288-295
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• 2021

This study was conducted to investigate the effect of end paper adsorbed with mask pack active ingredients on hair during permanent wave treatment. Permanent wave was performed with purchasing mask packs containing green tangerine, collagen, and Houttuynia cordate active ingredients among commercially available mask packs and adsorbing them to the end paper. As experimental methods, hair thickness, hair moisturizing power, tensile strength, hair epidermis observation using SEM, and hair constituent element analysis using EDS were performed. As a result of the experiment, it was confirmed that the experimental group treated with Houttuynia cordate active ingredient on the end paper had a hair protection effect as a result of hair thickness, tensile strength, hair epidermis observation, and hair component analysis. In addition, it was confirmed that the experimental group treated with green tangerine active ingredient on the end paper contained a relatively large amount of moisture in the hair moisturizing power test result. It is hoped that the development and research of various materials and tools will proceed so that basic cosmetic products containing active ingredients can be developed and used as hair cosmetics, and applied during chemical treatment in the industrial field.