• Child Health Nursing Research
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• v.7 no.1
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• pp.62-73
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• 2001

The purpose of the study is to identify the differences about knowledge and attitude between the subjects exposed to pc pornography and the control group not exposed to pc pornography. The study was executed from July 12 through July 16. The subjects were 423 middle school boys. The comparison points were their ethical sexual knowledges and sexual attitudes. The collected data was analysed by SPSS WIN(including multiplicand, percentage, χ²-test, revised Fisher and t-test). The results of their study were as follows ; 1. The pc-related characteristics of the subjects. The subjects exposed pc pornography showed 51.8％ rate of exposure to printed pornography. The control group showed the rate of 26.4％. The former group owned their pc(81.5％), however, the latter group showed 66.7％. The former group set their pc sets in their study rooms(66.1％) however, the latter group installed those in their study rooms(73.6％). The former group experienced internet pc communications(62.5％),however, the latter group showed 40.2％. The former group made use of their pc sets in recreation(entertainment) programs(77.0％), however, the latter group showed the rate of 67.8％. The former group showed that their school performance levelled up after their pc manipulation(80.0％), however, the latter group showed the rate of 86.2％. The former group replied that their pc manipulation contributed to their friendship(50.3％), however, the latter group showed the higher rate of 74.7％. The both groups replied that their family dialogs and contacts rather reduced (78.9％ and 78.2％ respectively). The both groups revealed that they reduced the TV watching the rate 76.5％ and 48.3％ respectively. The differences between two groups were surveyed in the level of 95％ significance and the items such as 'contacts to printed pornography, pc possession or none, pc use rate, friendship occasions and the reduced time of TV watching' showed the significant differences. 2. The differences of two groups' sexual knowledges. As to the sexual knowledges, the both groups showed 41.1 and 34.1 points against 100 points respectively. The statistical differences were significant(t=2.72, p=.007). The 5 items among 17 showed the significant differences between two groups. 'The concept of masturbation' was χ²=5.033, p=.025. 'The prejudice to masturbation' showed χ²=9.902, p=.002 'The difference between female and male as to sexual excitement' showed χ²=7.985, p=.005. 'The positiveness of masturbation' showed χ²=10.205, p=.001. 'The differences between two sexes as to sexual impulse and sexual desire' showed χ²=8.463, p=.004. In conclusion, The former group showed the higher knowledges than the latter group. 3. The differences of two groups' sexual attitudes. The 4 items such as 'the curiosity to the other sex'(t=2.22, p=.027), 'the attention to pornography'(t=3.39, p=.001), 'the permission to pre-marriage intercourse'(t=2.15, p=.032) and 'the preference to the female body exposure'(t=2.67, p=.008) showed the differences between two groups as to sexual attitudes.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.117.2-117.2
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• 2012

It is generally accepted that sudden compressions of the magnetosphere cause electromagnetic ion cyclotron (EMIC) wave growth by increasing the proton temperature anisotropy. These compression-associated EMIC waves are expected to be on higher latitudes (i.e., higher-L regions close to the magnetopause). In this study we examine Pc1 pulsations, which are believed to be generated by the EMIC instability, observed at subauroral latitude near the nominal plasmapause when the magnetosphere is suddenly compressed by solar wind dynamic pressure variations, using induction magnetometer data obtained from Athabasca, Canada (geomagnetic latitude = 61.7 N, L ~ 4.5). We identified 9 compression-associated Pc1 waves with frequencies of ~0.5-2.0 Hz. The wave activity appears in the horizontal H (positive north) and D (positive eastward) components. All of events show low coherence between H and D components. This indicates that the Pc1 pulsations in H and D oscillate with a different frequency. Thus, we cannot determine the polarization state of the waves. We will discuss the occurrence location of compression-associated Pc1 pulsations, their spectral structure, and wave properties.

• Biomolecules & Therapeutics
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• v.16 no.2
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• pp.106-112
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• 2008

The effects of harman and norharman on dopamine content and L-DOPA-induced cytotoxicity were investigated in PC12 cells. Harman and norharman decreased the intracellular dopamine content for 24 h. The $IC_{50}$ values of harman and norharman were 20.4 ${\mu}M$ and 95.8 ${\mu}M$, respectively. Tyrosine hydroxylase (TH) activity and TH mRNA levels were also decreased by 20 ${\mu}M$ harman and 100 ${\mu}M$ norharman. Under the same conditions, the intracellular cyclic AMP levels were decreased by harman and norharman. In addition, harman and norharman at concentrations higher than 80 ${\mu}M$ and 150 ${\mu}M$ caused cytotoxicity at 24 h in PC12 cells. Non-cytotoxic ranges of 10-30 ${\mu}M$ harman and 50-150 ${\mu}M$ norharman inhibited L-DOPA (20-50 ${\mu}M$)-induced increases of dopamine content at 24 h. Harman at 20-150 ${\mu}M$ and norharman at 100-300 ${\mu}M$ also enhanced LDOPA (20-100 ${\mu}M$)-induced cytotoxicity at 24 h. These results suggest that harman and norharman decrease dopamine content by reducing TH activity and aggravate L-DOPA-induced cytotoxicity in PC12 cells.

• Resources Recycling
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• v.20 no.5
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• pp.46-51
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• 2011

An extraction study of neodymium (Nd) was investigated with different individual and mixer of extractants such as PC88A, D2EHPA, Cyanex 272, Versatic acid 10 and D2EHPA+Alamine-304-1, D2EHPA+Alamine-308, D2EHPA+TBP, D2EHPA+TOPO, PC88A+Alamine-336 and PC88A+TBP respectively. In all cases, it was observed that the extraction percentage of Nd increased with increasing equilibrium pH and extractant concentration but rather opposite observation was found that the extraction percentage of Nd decreased with increasing TBP concentration along with D2EHPA. Adding TBP to PC88A had no favorable effect on the extraction of Nd, whereas use of a mixture of PC88A with Alamine336, increased the extraction percentage of Nd under the same condition. Based on our experimental studies, this paper reports the results on the basic approach and extraction of neodymium.

• BMB Reports
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• v.34 no.5
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• pp.446-451
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• 2001

The interaction of cytochrome c with binary phospholipid mixtures was investigated by solid-state $^2H$- and $^{31}P$-NMR. To examine the effect of the interaction on the glycerol backbones, the glycerol moieties of phosphatidylcholine (PC), and cardioliph (CL) were specifically deuterated. On the binding of cytochrome c to the binary mixed bilayers, no changes in the quadrupole splittings of each of the components were observed for the PC/PG, PE/CL and PE/PG liposomes. In contrast, the splittings of CL decreased on binging of protein to the PC/CL liposomes, although those of PC did not change at all. This showed that cytochrome c specifically interacts with CL in PC/CL bilayers, and penetrates into the lipid bilayer to some extent so as to perturb the dynamic structure of the glycerol backbone. This is distinctly different from the mode of interaction of cytochrome c with other binary mixed bilayers. In the $^{31}P$-NMR spectra, line broadening and a decrease of the chemical shift anisotropy were observed on the binding of cytochrome c for all binary mixed bilayers that were examined. These changes were more significant for the PC/CL bilayers. Furthermore, the line broadening is more significant for PC than for CL in PC/CL bilayers. Therefore, it can be concluded that with the polar head groups, not only CL but also PC are involved in the interaction with cytochrome c.

• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2391-2399
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• 2014

Novel dual responsive pectin hydrogels composed from poly(acrylamidoglycolic acid-co-vinylcaprolactam)/Pectin (PAV-PC) and also PAV-PC hydrogels are used as templates for the production of silver nanoparticles. 5-Fluorouracil is an anticancer drug and has been loaded in situ into PAV-PC hydrogels. Structure and morphology characterization of PAV-PC hydrogels were investigated by fourier transform infrared spectroscopy, differential scanning calorimetry, thermo gravimetric analysis, X-ray diffraction studies, scanning electron microscopy and transmission electron microscopy. The results revealed a molecular level dispersion of the drug in PAV-PC hydrogels. In vitro release of 5-fluorouracil from the PAV-PC hydrogels has been carried out in GIT fluids as well as in various temperatures. 5-Fluorouracil released from PAV-PC hydrogels was 50% at pH 1.2, and 85% at pH 7.4 within 24 h. The release profile was characterized with PAV-PC hydrogels and initial burst effect was significantly reduced in two buffer media (1.2 and 7.4), followed by a continuous and controlled release phase, the drug release mechanism from polymer was due to Fickian diffusion. In situ fabrication of silver nanoparticles inside the hydrogel network via the reduction of sodium borohydrate by PAV-PC chains led to hydrogel nanocomposites. The diameter of the nanocomposites was about 50-100 nm, suitable for uptake within the gastrointestinal tract due to their nanosize range and mucoadhesive properties. These nanocomposite PAV-PC hydrogels showed strong antimicrobial activity towards Bacillus subtilis (G+ve) and Escherichia coli (G-ve).

• Korean Journal of Food Science and Technology
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• v.46 no.4
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• pp.483-488
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• 2014

To examine the physiological effects of broccoli (Brassica oleracea var. italica) leaf, the bioavailable compounds in broccoli leaf extract, and its in vitro neuroprotective effects against $H_2O_2$-induced oxidative stress were examined in this study. The chloroform fraction of broccoli leaf extract had the highest total phenolic content of all the fraction than others, and the highest 2,2"-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical-scavenging activity and malondialdehyde (MDA) inhibitory effect. Intracellular reactive oxygen species (ROS) accumulation resulting in $H_2O_2$-treated in PC12 cells was significantly lower when the chloroform fraction was present in the medium compared to that in PC12 cells treated with $H_2O_2$ alone. In a cell viability assay performed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), the chloroform fraction showed protective effects against $H_2O_2$-induced neurotoxicity and inhibited lactate dehydrogenase (LDH) release into the medium. High-performance liquid chromatography (HPLC) analysis showed that ferulic acid was the predominant phenolic compound in chloroform fraction of broccoli leaf.

• Korean Journal of Materials Research
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• v.10 no.1
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• pp.7-14
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• 2000

The object of this study was to improve electrophotographic photoreceptor using metal free-phthalocyanine dye sensitized system. In here a various types of metal free-phthalocyanine and polymers and hydrazone were used as charge generation material(CGM) and binder, respectively, and also the hydrazone derivative or zinc complex was used as charge transport material(CTM). It was found that $x-H_2Pc$ showed the highest sensitivity among the ${\alpha}-$, ${\beta}-$ and x- metal free-phthalocyanine($x-H_2Pc$) as CGM. The photoreceptor made by $x-H_2Pc$ and hydrazone derivative as CGM and CTM, respectively, showed the highest ratio of dark decay having 73.1% and the good sensitivity of $1.50lux{\cdot}sec$ compared to other photoreceptors.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2013.05a
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• pp.717-718
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• 2013

• Molecules and Cells
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• v.20 no.2
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• pp.280-287
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• 2005

The insulin-mediated Ras/mitogen-activated protein (MAP) kinase cascade was examined in SK-N-BE(2) and PC12 cells, which can and cannot produce reactive oxygen species (ROS), respectively. Tyrosine phosphorylation of the insulin receptor and insulin receptor substrate 1 (IRS-1) was much lower in SK-N-BE(2) cells than in PC12 cells when the cells were treated with insulin. The insulin-mediated interaction of IRS-1 with Grb2 was observed in PC12 but not in SK-N-BE(2) cells. Moreover, the activity of extracellular-signal-related kinase (ERK) was much lower in SK-N-BE(2) than in PC12 cells when the cells were treated with insulin. Application of exogenous $H_2O_2$ caused increased tyrosine phosphorylation and Grb2 binding to IRS-1 in SK-N-BE(2) cells, while exposure to an $H_2O_2$ scavenger (N-acetylcysteine) or to a phophatidylinositol-3 kinase inhibitor (wortmannin), and expression of a dominant negative Rac1, decreased the activation of ERK in insulin-stimulated PC12 cells. These results indicate that the transient increase of ROS is needed to activate ERK in insulin-mediated signaling and that an inability to generate ROS is the reason for the insulin insensitivity of SK-N-BE(2) cells.