• The Plant Pathology Journal
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• 제20권1호
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• pp.1-6
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• 2004

The diseases caused by Xylella fastidiosa are associated with aggregation of the bacteria m xylem vessels, formation of a gummy matrix and subsequent blockage of water uptake. In the closely related pathogen, Xanthomonas campestris, xanthan gum is known to be an important virulence factor, probably contributing to bacterial adhesion, aggregation and plugging of xylem. Xanthan gum, produced by X. campestris, is an extra-cellular polysaccharide consisting of a cellulose backbone ($\bate$-1,4-linked D-glucose) with trisaccharide side chains composed of mannose, glucuronic acid and mannose attached to alternate glucose residues in the backbone. We had constructed a mutant of X. campestris lacking gumI gene that is responsible for adding the terminal mannose for producing modified xanthan gum which is similar to xanthan gum fromX. fastidiosa. The modified xanthan gum degrading endgphytic bacterium Acineto-bacter johnsonii GX123 isolated from the oleander infected with leaf scorch disease.

• 융합정보논문지
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• 제10권4호
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• pp.140-150
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• 2020

본 연구는 직장인의 직무 스트레스가 구강 자각증상에 미치는 영향을 파악하고자 경기도 일부 지역 내 직장인을 대상으로 설문 조사를 시행하였다. 수집된 자료는 SPSS 21.0 프로그램으로 분석하였으며 그 결과, 직무 스트레스 하위 요인 중 직무 불안정은(p<.01)저작 장애에, 직무 요구는(p<.01)잇몸 출혈 및 잇몸질환에, 긍정적 조직체계는 구취와(p<.05)잇몸 출혈 및 잇몸질환에(p<.01)유의한 영향을 미치는 것으로 나타났다. 따라서 직장인의 직무 스트레스에 대한 효율적인 관리 방안을 마련하고, 직무 스트레스와 관련된 구강 자각증상을 예측한다면 직장인의 계속 구강 건강관리는 물론 성인 구강 건강증진에 도움이 될 것으로 판단된다.

• Journal of Periodontal and Implant Science
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• 제53권2호
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• pp.97-98
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• 2023

• 한국치위생학회지
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• 제16권3호
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• pp.463-469
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• 2016

Objectives: The purpose of the study is to investigate the effect of chewing gum containing Prunus mume extract(PME) on the change of saliva ingredients. On the basis of the biological background of molecules and diagnostic indices in the use of saliva, the mastication effect of chewing gum containing PME was demonstrated in terms of secretory IgA concentration and total protein concentration in stimulated saliva. Methods: This study is an experimental research on the use of a research design before and after applying a randomized control group. Participants were distributed randomly to the experimental group and the control group, respectively. The experiment group was instructed to masticate the chewing gum containing PME for 10 minutes for one month after each meal within 30 minutes. Salivary secretion was collected by the participants between 8 and 10 a.m in the morning in the research office. For the measurement of secretory IgA and total protein concentrations in the saliva, indirect enzyme-linked immunosorbent assay(ELISA) was used. Results: The salivation stimulation rate was significantly increased after four weeks of masticating chewing gum containing PME after each meal(p<0.001). Mastication of chewing gum containing PME for four weeks decreased the concentration of secretory IgA much more significantly than that after mastication for one week(p=0.003). The concentration of total protein in the saliva was decreased after four weeks in the experimental and control groups. Conclusions: Mastication of chewing gum containing PME stimulated salivary secretion and led to oral disease prevention in patients with xerostomia. Furthermore, it seems to be urgent to seek measures that can be utilized in intervention for patients with xerostomia.

• 한국융합학회논문지
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• 제10권5호
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• pp.63-70
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• 2019

구강질환인 치주질환은 학령기 후반에 치은염으로 시작되어 청소년기에 점차 증가 하면서 청장년기에 이르기까지 유병률은 계속 증가되어 결국 치아상실에 이르는 만성질환으로 전 생애 예방관리가 매우 중요하다. 치주질환은 구강건강행위를 통해 예방하고 관리될 수 있기 때문에 성인의 구강건강행위와 치주질환간의 관련성을 연구하고 이에 대한 중요성을 강조하고자 한다. 국민건강영양조사 제6기 3차(2015년)년도 자료를 활용하여 연구대상자의 구강건강행위에 따른 치주질환 유병률 비교결과 잇몸병 치료, 잇솔질 시기, 치실, 치간칫솔 사용, 주관적 구강건강상태에서 통계적 의미가 있었다. 구강건강행위 습관이 치주질환과 관련이 있음을 고려할 때 올바른 구강위생관리를 위한 구강보건교육 프로그램의 개발과 실천을 위한 체계적인 추가 연구를 제안한다.

• 치위생과학회지
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• 제10권4호
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• pp.233-239
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• 2010

The study of the elderly and poor oral status interpersonal relationships and smooth social life limited to give is the social alienation and isolation, promoting to having problems with a sense of the elderly subjective oral health status and social efficacy affects whether analyzed. 1. Subjective oral health status authoring feel healthy food disorders, toothache, periodontal problems, tmj pain, dry mouth, bad breath symptoms such as 'sometimes' 'often' than a 'no' if you appear to be a highly subjective and social efficacy Efficacy of oral health status and social influence were more (p<0.01). 2. Subjective oral health status of the seven kinds of sub-variable that oral health status, food authoring disorders, toothache, gum disease, jaw joint or more, dry mouth, bad breath instantly and look at the relationship between social efficacy oral health status, ability of mastication, pain in oral, gum disease, tmj pain, dry mouth, presence of halitosis than positive (+) was correlated.

• 치위생과학회지
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• 제21권1호
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• pp.45-51
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• 2021

Background: Periodontal disease, also known as gum disease, is a major dental inflammatory disease with a very high prevalence; it is the main cause of tooth loss. Therefore, diagnostic biomarkers that can monitor gum inflammation are important for oral healthcare. Since the gingival crevicular fluid (GCF) adequately reflects changes in the periodontal environment, they have become a target for the development of effective diagnostic biomarkers for periodontitis. In the present study, the level of the target molecules suggested as diagnostic biomarkers for periodontitis were analyzed in GCF samples collected from healthy individuals and periodontitis patients. In addition, useful targets for the diagnosis of periodontitis were evaluated. Methods: GCF samples were collected from healthy individuals and periodontitis patients using absorbent paper points. SDS-PAGE and Coomassie staining were performed for protein analysis. The protein concentrations of GCF specimens were determined using the Bradford method. The levels of the target molecules appropriate for diagnosing periodontal disease were measured by ELISA, according to the manufacturer's protocol. Results: The protein concentration of GCF collected from periodontitis patients was 3.72 fold higher than that in an equal volume of GCF collected from healthy individuals. ELISA analysis showed that the level of interukin-6 (IL-6), IL-8, metalloproteinases 2 (MMP-2), MMP-9, tumor necrosis factor-alpha (TNF-α), azurocidin, and odontogenic ameloblast-associated protein (ODAM) were higher in the GCF samples from the periodontitis patients than in those from the healthy individuals. However, the level of IL-6 and TNF-α were relatively low (> 5 pg/ml). The prostaglandin E2 (PGE2) levels were not significantly different between the two GCF samples. Conclusion: These results indicate that IL-8, MMP-2, MMP-9, azurocidin, and ODAM are potentially useful diagnostic biomarkers for periodontitis; combining multiple biomarkers will improve the diagnostic accuracy of periodontitis.

• 한국치위생학회지
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• 제16권6호
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• pp.893-907
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• 2016

Objectives: The purpose of this study was to identify the related factors of dental caries and periodontal disease in adolescents from Korean multicultural families, thereby helping to reduce the prevalence rate of oral disease. Methods: The subjects were 710 multicultural adolescents recruited using a web-based survey, National 2015 Korean Youth Risk Behavior, from the Korean Center for Disease Control. A multicultural family was defined in this study as one having an immigrant mother or father. Oral symptoms included dental caries and periodontal disease. Toothache was defined as a symptom of dental caries. Tender or bleeding gums were defined as symptom of periodontal disease. For statistical analysis, Statistical Package for Social Sciences (SPSS) Version 21.0 for Windows was used. Descriptive analysis and a Chi-square test were conducted to determine the factors associated with general characteristics, health behavior, and oral health behavior. Finally, to investigate the associations among oral disease symptoms, logistic regression analysis was performed. Results: Toothache was significantly higher in female 1.52 (95% CI; 1.45-1.60), high school 1.23 (95% CI; 1.18-1.28), women school 1.10 (95% CI; 1.05-1.16), individuals with poor economic status 1.45 (95% CI; 1.30-1.52), and participants who consumed alcohol 1.32 (95% CI; 1.27-1.37). Toothache related to perceived health status was significantly lower in the healthy group 0.69 (95% CI; 0.64-0.75), and was higher in usual stress group 1.65 (95% CI; 1.57-1.74). Gum bleeding was significantly higher in female 1.32 (95% CI; 1.27-1.37), high school 1.15 (95% CI; 1.10-1.19), and individuals with poor economic status 1.38 (95% CI; 1.27-1.50). Gum bleeding related to perceived health status was significantly lower in the healthy group 0.68 (95% CI; 0.63-0.74), and was higher in usual stress group 1.54 (95% CI; 1.46-1.62). Conclusions: Taking into account of social and economic levels, and dietary habits in the multicultural families adolescents, further education and support will be needed for oral disease prevention and early treatment.

• 대한한의학방제학회지
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• 제11권1호
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• pp.45-55
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• 2003

From the study of the symptom, pathology in prescription of Ha-Tong from The Bangyakhapeun. I have reserched 163 prescription. It can be concluded as follows. 1. Prescription about Fecal disease which was the most as 11.66% of the whole, following order Internal disease(6.75%), Uterus Disease(5.52%) Sick-by-Cold Disease(5.52%), Eye Disease(4.91%), Blood Disease(4.91%), Unbalanced humoral status Disease(4.91%), Gynecologic Disease(4.91%). 2. The Fecal Disease divide diarrhea and dysentery; The Internal Disease divides with Sik-sang(食傷) Chu-sang(酒傷), Sik-juck-yu-sang-han(食積類傷寒), Carbonic acid, Vomiting acid; The Uterus Disease divides with Urinnary Disadvantage, Urinary retention, Incontinence; The Sick-by-Cold Disease divides with yang-myung-byung(陽明病), sang-han-goi-jng(傷寒壞證), sang-han-bun-gal(傷寒煩渴), sang-han-sum-ou, sang-han-hyul-jng(傷寒血證), sang-han-ja-ri(傷寒自利), sang-han-bun-jo-jng(傷寒煩燥證). 3. The Diarrhea and Dysentery many used o-ryung-san, hwng-gum-jak-yak-tang(黃芩芍藥湯) hyang-ryun-hwan(香連丸) etc, and The Internal Disease many used pyung-we-san(平胃散) as a basic prescripton. 4. The organ problem use the Sil-yuol(實熱) of the liver, stomach, lung, uterus, small intestine; six natural factors problem used the Sil-jng(實證) of the wind, fire, heat, cold, dampness; And used Unbalanced humoral status, lntrnal hurt, qi and blood, seven extream feeling.

• 한국융합학회논문지
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• 제11권7호
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• pp.273-280
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• 2020

20대 초반 여대생을 대상으로 치아건강도와 치은건강도 그리고 구강청결도를 분석해보고자 한 결과 치아건강도를 예측할 수 있는 우식성박테리아와 타액의 산성도, 암모니아와 관련이 높게 나타났으며, 치은건강도를 예측할 수 있는 혈액과 백혈구, 단백질이 관련이 있는 것으로 조사되었다(p<0.01). 특히 구강내 미생물의 대사산물인 암모니아는 혈액과 백혈구와 관련이 높게 조사되어, 구강청결도와 관련이 있는 것으로 조사되었다(p<0.01). 따라서 타액측정시스템(Sill-Ha ST-4910)의 구강병 발생 7가지 예측 위험도와 본 실험 결과가 일치되어 향후 타액측정시스템은 진료실에서 활용 가능성이 있는 것으로 나타났다. 다만, 본 연구의 제한점은 노령자나 전신질환이나 만성질환이 없는 건강한 청년을 대상으로 하였기에 일반화하기에는 무리가 있다고 생각하며 후속 연구를 필요로 한다.