• 제목/요약/키워드: guided mode

검색결과 261건 처리시간 0.029초

천연물로부터의 세포내 효소 활성 조절물질의 탐색 및 기능 연구: 갈근의 알코을 탈수소효소 저해 활성 성분 (Studies on the Screening of Bioactive Compound Acting on Intracellular Enzymes from Natural Products and Its Mode of Action : Inhibitory Component of Puerariae Radix on Alcohol Dehydrogenase Activity)

  • 이현주;오민아;최영희;이강만
    • 약학회지
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    • 제45권5호
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    • pp.500-505
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    • 2001
  • Puerariae Radix is one of the medicinal plants used in oriental medicine for hangover, It has been claimed for several pharmacological effects including anti-alcohol abuse, antidipsotropic activity and anti-alcohol intoxication. In connection with Puerariae Radix effects, an activity-guided purification of active substance on alcohol dehydrogenase (hnH) was carried-out. The most active compound was isolated as puerarin (C$_{21}$H$_{20}$ O$_{9}$ ), molecular weight 416. Puerarin inhibited ADH noncompetitively against ethanol or NAD$^{+}$./.

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Nonlinear Displacement Discontinuity Model for Generalized Rayleigh Wave in Contact Interface

  • Kim, No-Hyu;Yang, Seung-Yong
    • 비파괴검사학회지
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    • 제27권6호
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    • pp.582-590
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    • 2007
  • Imperfectly jointed interface serves as mechanical waveguide for elastic waves and gives rise to two distinct kinds of guided wave propagating along the interface. Contact acoustic nonlinearity (CAN) is known to plays major role in the generation of these interface waves called generalized Rayleigh waves in non-welded interface. Closed crack is modeled as non-welded interface that has nonlinear discontinuity condition in displacement across its boundary. Mathematical analysis of boundary conditions and wave equation is conducted to investigate the dispersive characteristics of the interface waves. Existence of the generalized Rayleigh wave(interface wave) in nonlinear contact interface is verified in theory where the dispersion equation for the interface wave is formulated and analyzed. It reveals that the interface waves have two distinct modes and that the phase velocity of anti-symmetric wave mode is highly dependent on contact conditions represented by linear and nonlinear dimensionless specific stiffness.

상태 공간 외란관측기 기반의 임피던스 제어와 ISMC를 이용한 메카넘 휠 AGV의 강인 궤도 추적 제어 (Robust Trajectory Tracking Control of Mecanum Wheeled AGV Using State Space Disturbance Observer Based Impedance Control and ISMC)

  • 천효석;박승규
    • 로봇학회논문지
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    • 제18권2호
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    • pp.155-163
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    • 2023
  • Auto Guided Vehicle (AGV) equipped with mecanum wheels can move in all directions, unlike ordinary wheeled AGVs. In this paper, we propose a robust trejectory tracking control method for the mecanum wheeled AGVs in the presence of disturbances. It is constructed by combining impedance control with Integral Sliding Mode Control (ISMC), which shows robust performance against disturbances, and adding a disturbance observer (DOB) that estimates and removes disturbances. Simulation result using MATLAB/SIMULINK shows that the proposed control method has robust performance in tracking the reference trajectory under the circumstance with disturbance. The control performance is further improved when the disturbance observer is additionally used. In addition, the performance of the proposed control method was verified through experiment. It shows the result of tracking the set trajectory well.

신체표현을 활용한 영상미디어 음악치료프로그램모형 개발 -색깔과 화음 및 다이나믹을 중심으로- (Development of Model for Video Media Music Therapy Program Using Body Expression -Based on Color, Harmony and Dynamics-)

  • 신연숙;조성희
    • 한국콘텐츠학회논문지
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    • 제12권8호
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    • pp.429-437
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    • 2012
  • 본 연구는 신체표현을 활용한 색깔과 화음, 다이내믹을 연결하여 일어나는 변화에 목적을 두고 있다. 본 연구를 통하여 영상미디어 음악치료 프로그램 모형개발을 위한 기초 자료 수집을 위해 심리적으로 화음과 다이내믹이 색깔에 변화를 준다는 것을 탐색하였다. 영상매체에서 음악은 비언어적 의사소통으로 많은 분야에서 사용된다. 특히 음과 색깔 관계의 심리적 변화를 통하여 가상과 현실의 갭을 줄이는 데에 가장 효과적인 도구이며 사용자는 메시지와 의미에 대해 우리의 감성을 유도한다. GIM (Method of Guided Imagery and Music)은 인간의 내면세계를 탐색하고 음악에 유도된 다양한 심상 경험을 통해 상징적 의미와 통찰로 자신을 이해하고 문제를 해결해가도록 하는 음악치료방법으로 인간의 내적세계를 광범위하게 다룬다. 본 연구를 통하여 영상미디어라는 도구를 기존의 음악치료에서 사용되어져 왔던 수동적이고 소극적인 음악 감상 활용방법에서 탈피하고 직접 몸으로 체험하는 능동적이고 적극적인 음악치료 프로그램 모형을 적용시켜 나아가 오늘날 급격히 변화하는 청소년기의 사회적응문제에서 긍정적 효과를 줄 수 있는 음악치료 프로그램개발 모형을 위한 기초 자료로 삼고자 한다.

Power Doppler ultrasound-guided sialography using the phenomenon of increased blood flow: A technical report

  • Oh, Song Hee;Seo, Yu-Kyeong;Kim, Gyu-Tae;Choi, Yong-Suk;Hwang, Eui-Hwan
    • Imaging Science in Dentistry
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    • 제49권4호
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    • pp.301-306
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    • 2019
  • Purpose: This report presents a procedure for performing power Doppler ultrasound-guided sialography using the phenomenon of increased blood flow and illustrates its application to practical patient cases. Materials and Methods: The salivary gland was scanned using ultrasound equipment (GE LOGIQ5 Expert® device; GE Medical Systems, Milwaukee, WI, USA) to identify pathological findings related to the patient's chief complaint. To identify the orifice of the main duct, it should be cannulated using a lacrimal dilator. After inserting the catheter into the cannulated main duct, the position of the catheter within the duct was confirmed by ultrasound. A contrast agent was injected until the patient felt fullness, and ultrasound (B-mode) was used to confirm whether the contrast agent filled the main canal and secondary and tertiary ducts. Then, power Doppler ultrasound was performed to determine whether the salivary gland had increased blood flow. Results: In 2 cases in this report, a power Doppler ultrasound scan showed a significant increase in blood flow after contrast medium injection, which was not observed on a preoperative scan. Conclusion: Power Doppler ultrasound was found to be a simple, safe, and effective tool for real-time sialography monitoring.

프리즘 커플러를 이용한 도파로형 Au/$SiO_2$ 나노 혼합박막의 광 스위칭 특성 연구 (Study of the optical switching properties in waveguide type Au/$SiO_2$ nanocomposite film using prism coupler)

  • 조성훈;이순일;이택성;김원목;이경석
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2008년도 하계학술대회 논문집 Vol.9
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    • pp.76-76
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    • 2008
  • The resonance properties due to the surface plasmon(SP) excitation of metal nanoparticles make the nanocomposite films promising for various applications such as optical switching devices. In spite of the well-known ultra-sensitive operation of optical switches based on a guided wave, the application of nanocomposite film(NC) has inherent limitation originating from the excessive optical loss related with the surface plasmon resonance(SPR). In this study, we addressed this problem and present the experimental and theoretical analysis on the pump-probe optical switching in prism-coupled Au(1 vol.%):$SiO_2$ nanocomposite waveguide film. The guided mode was successfully generated using a near infrared probe beam of 1550 nm and modulated with an external pump beam of 532 nm close to the SPR wavelength. We extend our approach to ultra-fast operation using a pulsed laser with 5 ns pulse width. To improve the switching speed through the reduction in thermal loading effect accompanied by the resonant absorption of pump beam light, we adopted a metallic film as a coupling layer instead of low-index dielectric layer between the high-index SF10 prism and NC slab waveguide. We observed great enhancement in switching speed for the case of using metallic coupling layer, and founded a distinct difference in origin of optical nonlinearities induced during switching operation using cw and ns laser.

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Type4 복합재 용기의 돔 형상에 따른 파열형태에 관한 연구 (A Study on Failure Modes of Type4 Composite Pressure Cylinders according to Shapes of Domes)

  • 조성민;김광석;조민식;이선규;이승국;류성기
    • 한국기계가공학회지
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    • 제16권5호
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    • pp.13-18
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    • 2017
  • In this work the augmented safety of Type 4 composite vessel in accordance with uniform-stress design has been demonstrated through a series of burst tests and structural analyses. For this end, three sample vessels were used: (1) designed as guided by the isotensoid dome theory (called iso-dome cylinder); (2) with dome longer compared to uniform-stress design (called prolate cylinder); and (3) with dome wider than uniform-stress design (called oblate cylinder). Structural analyses have been performed using ABAQUS finite element code based on the periodic symmetry to circumferential direction. As a result, the maximum stresses are induced around the bodies of all three cylinders. However, the analyses, with the assumption of possible defect demonstrate that the maximum stresses are induced around the dome knuckles for the prolate and the oblate cylinders. The results of the burst tests for the three cylinders show that the burst initiates from the cylinder body of the iso-dome cylinder and from the dome knuckles of the prolate and the oblate cylinders. Finally, it is recommended that, to comply with DOT CFFC 2007, the dome shape should be designed and fabricated as guided by the isotensoid dome theory.

Predictive model of fatigue crack detection in thick bridge steel structures with piezoelectric wafer active sensors

  • Gresil, M.;Yu, L.;Shen, Y.;Giurgiutiu, V.
    • Smart Structures and Systems
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    • 제12권2호
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    • pp.97-119
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    • 2013
  • This paper presents numerical and experimental results on the use of guided waves for structural health monitoring (SHM) of crack growth during a fatigue test in a thick steel plate used for civil engineering application. Numerical simulation, analytical modeling, and experimental tests are used to prove that piezoelectric wafer active sensor (PWAS) can perform active SHM using guided wave pitch-catch method and passive SHM using acoustic emission (AE). AE simulation was performed with the multi-physic FEM (MP-FEM) approach. The MP-FEM approach permits that the output variables to be expressed directly in electric terms while the two-ways electromechanical conversion is done internally in the MP-FEM formulation. The AE event was simulated as a pulse of defined duration and amplitude. The electrical signal measured at a PWAS receiver was simulated. Experimental tests were performed with PWAS transducers acting as passive receivers of AE signals. An AE source was simulated using 0.5-mm pencil lead breaks. The PWAS transducers were able to pick up AE signal with good strength. Subsequently, PWAS transducers and traditional AE transducer were applied to a 12.7-mm CT specimen subjected to accelerated fatigue testing. Active sensing in pitch catch mode on the CT specimen was applied between the PWAS transducers pairs. Damage indexes were calculated and correlated with actual crack growth. The paper finishes with conclusions and suggestions for further work.

레이저에 의해 생성된 Si 박막의 주기적 표면 구조에서의 도파모드 공진 연구 (Guided-mode Resonances in Periodic Surface Structures Induced on Si Thin Film by a Laser)

  • 이지혁;이윤주;홍현;조은솔;박지영;김주현;강민진;황의선;정병호
    • 한국광학회지
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    • 제34권6호
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    • pp.241-247
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    • 2023
  • 본 연구에서는 355 nm 파장의 나노초 레이저를 비정질 실리콘 박막에 조사하여 형성된 주기적 laser-induced periodic surface structure (LIPSS) 구조의 분광학적 특성을 연구하였다. 지름 196 ㎛의 가우시안 빔을 단위면적당 레이저 펄스 190-280회, 레이저 빔의 세기는 100-130 mJ/cm2 범위에서 'ㄹ' 자 형태로 2차원 스캔하였다. 그 결과 Si 박막 표면에 ~300 nm 주기의 LIPSS 구조가 레이저 편광에 수직 방향으로 정렬되었다. 시료의 투과율 스펙트럼을 측정하여 transverse-electric 편광과 transverse-magnetic 편광에 대해서 각각 700 nm, 500 nm 근방에서 dip이 관측되었다. 이 현상을 설명하기 위해 1차원 격자구조 모델을 이용하여 rigorous coupled-wave analysis를 이용한 시뮬레이션을 하여 편광에 따른 도파모드 공진에 의한 특성임을 규명하였다.

초음파 투과법을 이용한 록볼트 그라우팅의 건전도 평가 (Integrity evaluation of rock bolt grouting using ultrasonic transmission technique)

  • 한신인;이종섭;이용준;남석우;이인모
    • 한국터널지하공간학회 논문집
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    • 제9권1호
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    • pp.75-82
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    • 2007
  • 본 연구의 목적은 록볼트의 건전도를 평가하기 위하여 록볼트의 비파괴시험을 기술하고 비파괴시험의 적용성을 조사하는 것이다. 록볼트 자체와 그라우팅재를 포함한 록볼트의 건전도를 평가하기 위하여, 수치해석 및 실험적 방법을 이용한 두 가지 방법이 적용되었다. 수치해석적 방법에서는 "DISPERSE" 프로그램을 이용하여 록볼트 시스템에서 유도파 전달시의 분산성분석을 수행하였다. 분산선도 곡선은 지중근입되어 있는 록볼트에 대하여 주변암반과 그라우팅재의 강성에 따라 신호파의 진폭감쇠정도와 주파수변화대비 전파속도의 영향을 보여준다. 이로 부터 록볼트의 건전도시험을 위한 최적의 주파수를 추정할 수 있으며, 그 결과L(1)모드에서$20{\sim}70kHz$가 최적의 주파수대역으로 선정하였다. 실험적 방법에서는 시험체를 제작한 후 현장조건을 모사하여 실내비파괴시험을 실시하였다. 비파괴 실험기법으로는 록볼트 선단부에 가진 센서를 부착, 매입하여 전기신호 가진에 의한 투과법을 적용하였다. 그라우팅과 주변암반에 의해 신호파의 전파속도와 진폭에 영향이 있으며, 그라우팅과 주변암반으로의 leaking 등에 의하여 신호파의 진폭이 감쇠하는 것으로 나타났다. 또한 시험체가 그라우팅으로 피복되어 있을 경우 자유구속 및 지중근입 조건에서 공동결함 크기가 증가함에 따라 무결함부에 비하여 진폭이 증가하였다. 그리고 수진된 신호파의 초동시간이 감소하여 전파속도는 전반적으로 선형적 증가 경향을 보였으며, 진폭변화에 비하여 전파속도가 공동결함비율 변화에 더 민감한 반응을 보였다. 본 연구는 록볼트의 건전도 평가시에 비파괴시험이 매우 유용한 방법임을 확인할 수 있었다.

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