• Journal of mucopolysaccharidosis and rare diseases
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• 제2권2호
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• pp.41-42
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• 2016

Today's mobile phones and tablet PCs offer a considerably wider range of functionalities than before. Mobile applications (apps) are increasingly used for managing various daily health tasks. Currently, more than 165,000 health-related apps are offered on all the stores of different platforms. Pf Jin and the Association for Research on MPS and Rare Diseases (AMARD) have helped Prader-Willi syndrome (PWS) families through medical information and family support since 2015. AMARD developed the first mobile application for Korean patients with PWS, which was released to a limited number of patients under the age of 3 and only provided to Android users. The first version of the PWS application focused on growth hormone therapy and the assessment of growth and development by parents in infant and early-childhood PWS patients. The 2016 version of the PWS application has been improved in many different ways. We have expanded the subjects of the application to late childhood and adolescent groups, changed the user interface accordingly, and made the application available for iOS users. We will show the specialized growth curves of older children with PWS. Therefore, patients with PWS over the age of 3 and their parents can assess the patients' growth. Additionally, we have upgraded the growth hormone therapy menu by improving the input system for the growth hormone therapy injection schedule and the daily growth profile (height and weight). We expect that the new version of the PWS application will help many PWS families cope with growth hormone therapy and evaluate the effects of growth hormones in better ways. Additionally, we are making a constant effort to provide more useful information about patients with PWS in many aspects.

• 한국기계가공학회지
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• 제14권2호
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• pp.112-120
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• 2015

In this study, the growth rate of surface cracks (da/dN) during the retardation period was analyzed in terms of effective stress intensity factor range(${\Delta}K_{eff}^*$) obtained by using the proposed effective plastic zone concept. Effective stress intensity factors obtained by using the effective plastic zone concept were smaller than those obtained by using Willenborg analysis. On the growth rate of surface cracks analyzed by ${\Delta}K$, the dependence of overload stress levels appears. On the growth rate by ${\Delta}K_{eff}$ obtained by Willenborg analysis, there is a linear relationship with two different slops between da/dN and ${\Delta}K_{eff}$. However, on the growth rate by ${\Delta}K_{eff}^*$ obtained by the proposed effective plastic zone concept, there is a linear relationship between da/dN and ${\Delta}K_{eff}^*$ that coincides with the results of constant amplitude loading.

• Asian-Australasian Journal of Animal Sciences
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• 제3권4호
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• pp.299-303
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• 1990

Twenty-four Harnai lambs 6 to 7 month old, weighing $16{\pm}2kg$ were used in a completely randomized design in growth and digestibility trials to study fourwing saltbush ratio supplemented with cotton seed cake. The animal were divided at random into three groups of 8 animals each. Three iso-nitrogenous (10.5% CP) experimental rations (1, 2 and 3) containing wheat straw + lucerne hay (24:76); fourwing saltbush (Atriplex canescens) + cotton seed cake (71:29); and wheat straw + cottonseed cake (41:59); respectively, were allotted to each group randomly. All the animals were taken out for grazing in a dormant native range for about 3 hours in the afternoon during the growth trial. The growth trial lasted for 8 weeks followed by a digestibility trial. At the end of 8 weeks lambs on ration 3 had gained significantly (p<0.10) more weight compared to those on rations 1 and 2 which maintained their body weight. The crude protein digestibility of the fourwing saltbush based ration was comparable with the other two treatments (71 vs 70 and 71%). However, the digestibility of dry matter (41%), acid detergent fibre (13%) and neutral detergent fibre (22%) of this ration was significantly lower (p<0.10) than the other two diets. The results suggest that lambs can be maintained on fourwing saltbush during winter without significant loss in body weight with 30% extra protein concentrate supplementation.

• 대한전자공학회논문지
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• 제22권1호
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• pp.34-40
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• 1985

시스뎀 압력이 1.0 기압[대기압 공정]일 경우와 0.1 기압(감압 공정)일 경우에 대해, SiH2Cl2를 사용했을 때의 에퍼택셜층 및 폴리실리콘의 성장 현상과 HCI을 사용했을 때의 이것들의 에칭 현상을 조사하였다. 실험적으로 구한 성장 속도 및 에칭 속도에 대한 식들로부터 Sih2Cl2와 HCI을 혼합하여 사용할 경우에 대한 선화적 에퍼택시가 가능한 공정 조건이 예측되었다. 그 결과, 선택적 에퍼택셜 성장 영역이 감압 공정에서는 실험 범위내에서 존재하였지만 대기압 공정에서는 존재하지 않는 것으로 나타났다. 이 것은 대기압과 감압에서의 성장 속도 및 에칭 속도가 차이가 나기 때문에 기인하는 것이다.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.101.2-102
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• 2003

The ability of P. chlororaphis O6 to induce resistance to Erwinia carotovora subsp. carotovara SCCI and to promote growth in tobacco was demonstrated in microtiter assays on plants pre-inoculated at the root level with the bacteria before challenge with the leaf pathogen. To identify th bacterial determinants involved in induced systemic resistance and plant growth promotion, cell culture of O6 grown in King's medium B was fractionated with organic solvents and purified using various columns. in vivo and in vitro assays with samples from successive fractionation steps of the O6 supernatant led to the conclusion that antibacterial compounds were observed in aqueous layer, and to the isolation of fractions containing metabolites that retained most of the resistance-inducing activity (70：30, methanol：water) and the plant growth promotion (80：20 and 90：10, methanol：water) after ODS column chromatography. Although these molecules remain to be purified further and structurally characterized, its isolation is an addition to the range of determinants from plant growth-promoting rhizobacteria known to stimulate plant defence.

• 한국표면공학회지
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• 제31권6호
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• pp.345-358
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• 1998

The evolution of surface roughness and morphology in epitaxial Si and $Si_{0.7}Ge{0.3}$ alloys grown by UHV opm-beam sputter deposition onto nominally-singular, [100]-, and [110]-mi-scut Si(001) was investigated by stomic force microscopy and trasmission electron microscopy. The evolution of surface roughness of epitaxial Si films grown at $300^{\circ}C$ is inconsistent with conventional scaling and hyperscaling laws for kineti roughening. Unstable growth leading to the formation of mounds separated by a well-defined length scale is observed on all substrates. Contraty to previous high-temperature growth results, the presence of steps during deposition at $300^{\circ}C$ increases the tendency toward unstable growth resulting in a much earlier development of mound structures and larger surface roughnesses on vicival substrates. Strain-induced surface roughening was found to dominate in $Si_{0.7}Ge{0.3}$ alloys grown on singular Si(001) substrates at $T_S\ge450^{\circ}C$ where the coherent islands are prererentially bounded along <100> directions and eshibt {105} facetting. Increasing the film thickness above critical values for strain relaxation leads to island coalescence and surface smoothening. At very low growth temperatures ($T_s\le 250^{\circ}C$), film surfaces roughen kinetically, due to limited adatom diffusiviry, but at far lower rates than in the higher-temperature strain-induced regime. There is an intermediate growth temperature range, however, over which alloy film surfaces remain extremely smooth even at thicknesses near critical values for strain relaxation.

• 대한토목학회논문집
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• 제4권1호
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• pp.125-136
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• 1984

용접구조에서 피로파괴는 피로균열의 성장거동에 주로 지배를 받는다. 특히 용접방향과 피로균열 성장방향의 이방성은 용접부 피로파괴의 중요한 영향인자가 된다. 피로이력을 갖고 있는 강재와 피로이력이 없는 강재를 용접시 저 ${\Delta}K$ 영역에서는 모재의 재질적인 영향인자보다 잔류응력의 영향이 크게 작용하였다. 그러나 균열이 용착금속에서 성장을 하는 경우는 용착금속의 인성이 가장 중요한 영향인자가 되는 것으로 밝혀졌다. 특히 용착금속의 인성불균일은 $da/dN-{\Delta}K$ 관계를 넓게 분포시킨다.

• 대한기계학회논문집
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• 제16권1호
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• pp.63-69
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• 1992

본 연구에서는 특히 앞서 지적한 표면균열의 진전거동에 관한 연구와도 관련 하여 측면홈을 가진 중앙관통균열(side-grooved center cracked tension) 시험편에 대 해 피로균열 진전실험을 수행하고, 평면변형률 조건의 만족여부 및 응력강도계수 평가 방법에 관하여 검토하여 비교적 새로운 결과를 얻었으므로 여기에 보고하고자 한다.

• 한국생산제조학회지
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• 제8권2호
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• pp.126-136
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• 1999

We studied on crack growth retardation in single overloading condition. Crack tip branching which as the second mechanism on crack growth retardation was examined. Crack tip branching was observed to kinked type and forked type. It was found that the branching angle range was from 25 to 53 degree. The variations of crack driving force with branching angle were calculated with finite element method The variation of {{{{ KAPPA _I}}}}, {{{{ KAPPA _II}}}} and total crack driving force(K) were examined respectively So {{{{ KAPPA _I}}}}, {{{{ KAPPA _II}}}} and K mean to mode I, II and total crack driving force. Present model(Willenborg's model) for crack growth retardation prediction was modified to take into consideration the effects of crack tip branching When we predicted retardation with modified model. it was confirmed that predicted and experimental results coincided with well each other.

• 한국가시화정보학회지
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• 제12권1호
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• pp.13-17
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• 2014

The growth of micro bubble has been simulated under the variation of ambient pressure. The Rayleigh-Plesset equation governs the dynamic growth and collapse of a bubble according to pressure and temperature conditions. The Rayleigh-Plesset equation was solved by 4th-order Runge-Kutta method for wide range of pressure variations. As numerical parameters, the pressure difference between initial and final pressures, and the temporal pressure gradient are changed. The results show that the pressure difference has little effect on the growth rate of the micro bubble in the inertia controlled growth region. On the other hand, the growth rate increases linearly with the increase of the pressure gradient.