• Title/Summary/Keyword: growth optimization

Search Result 635, Processing Time 0.032 seconds

Optimization of Tannase Production by Aureobasidium pullulans DBS66

  • Banerjee, Debdulal;Pati, Bikas R.
    • Journal of Microbiology and Biotechnology
    • /
    • v.17 no.6
    • /
    • pp.1049-1053
    • /
    • 2007
  • Tannase production by Aureobasidium pullulans DBS66 was optimized. The organism produced maximum tannase in the presence of 1% tannic acid after 36 h. Maximum gallic acid accumulation was observed within 36 h and tannic acid in the fermented broth was completely degraded after 42 h of growth. Glucose had a stimulatory effect on tannase synthesis at 0.1% (w/v) concentration. The organism showed maximum tannase production with $(NH_4)_2HPO_4$ as nitrogen source. Shaking speed of 120 rpm and 50-ml broth volume have been found to be suitable for maximum tannase production.

Examination of three meta-heuristic algorithms for optimal design of planar steel frames

  • Tejani, Ghanshyam G.;Bhensdadia, Vishwesh H.;Bureerat, Sujin
    • Advances in Computational Design
    • /
    • v.1 no.1
    • /
    • pp.79-86
    • /
    • 2016
  • In this study, the three different meta-heuristics namely the Grey Wolf Optimizer (GWO), Stochastic Fractal Search (SFS), and Adaptive Differential Evolution with Optional External Archive (JADE) algorithms are examined. This study considers optimization of the planer frame to minimize its weight subjected to the strength and displacement constraints as per the American Institute of Steel and Construction - Load and Resistance Factor Design (AISC-LRFD). The GWO algorithm is associated with grey wolves' activities in the social hierarchy. The SFS algorithm works on the natural phenomenon of growth. JADE on the other hand is a powerful self-adaptive version of a differential evolution algorithm. A one-bay ten-story planar steel frame problem is examined in the present work to investigate the design ability of the proposed algorithms. The frame design is produced by optimizing the W-shaped cross sections of beam and column members as per AISC-LRFD standard steel sections. The results of the algorithms are compared. In addition, these results are also mapped with other state-of-art algorithms.

High Cell Density Culture of Alcaligenes eutrophus and Poly-$\beta$-hydroxybutyrate Production by Optimization of Medium Compositions (배지조성 최적화를 통한 Alcaligenes eutrophus의 고농동 세포배양 및 Poly$\beta$-hydroxybutyrate 생산)

  • 이용우;유영제
    • Microbiology and Biotechnology Letters
    • /
    • v.22 no.4
    • /
    • pp.401-406
    • /
    • 1994
  • The medium compositions of Alcaligenes eutrophus were optimized for increasing PHB productivity. It is very important to optimize the concentrations of inorganic salts and trace eleme- nts as well as carbon and nitrogen sources to maximize cell growth rate and productivity. The fed-batch culture of Alcaligenes eutrophus by dual feeding of ammonia water and glucose under optimized initial medium concentrations was carried out. Glucose was fed manually according to glucose consumption rate and ammonia water by pH-stat. The final cell concentrations and PHB content in 30 hours were 122 g/l and 65% of dry cell weight(yielding 79 g of PHB/l), respectively and 2.64 g/l/hr of PHB production rate was obtained.

  • PDF

Optimization analysis on collection efficiency of vacuum cleaner based on two-fluid and CFD-DEM model

  • Wang, Lian;Chu, Xihua
    • Advances in Computational Design
    • /
    • v.5 no.3
    • /
    • pp.261-276
    • /
    • 2020
  • The reasonable layout of vacuum cleaner can effectively improve the collection efficiency of iron filings generated in the process of steel production. Therefore, in this study, the CFD-DEM coupling model and two-fluid model are used to calculate the iron filings collection efficiency of vacuum cleaner with different inclination/cross-sectional area, pressure drop and inlet angle. The results are as follows: The CFD-DEM coupling method can truly reflect the motion mode of iron filings in pneumatic conveying. Considering the instability and the decline of the growth rate of iron filings collection efficiency caused by high pressure drop, the layout of 75° inclination is suggested, and the optimal pressure drop is 100Pa. The optimal simulation results based on two-fluid model show that when the inlet angle and pressure drop are in the range of 45°~65° and 70Pa~100Pa, larger mass flow rate of iron filings can be obtained. It is hoped that the simulation results can offer some suggestion to the layout of vacuum cleaner in the rolling mill.

Statistical Optimization of the Medium Components for the Production of Protopectinases by Bacillus subtilis

  • Shahbazian, Nafise;Ashtiani, Farzin Zokaee;Bonakdarpour, Babak
    • Food Science and Biotechnology
    • /
    • v.18 no.2
    • /
    • pp.442-448
    • /
    • 2009
  • In this study Bacillus subtilis PTCC 1023 was used for the production of protopectinase using soybean based media. The use of isolated soybean protein (ISP) and soybean flour resulted in similar protopectinase production and growth rates. The effect of medium composition on protopectinase production was studied using central composite design (CCD) methodology. The change in the concentration of ISP (1-7%), glucose (0-10%), and phosphate (0.1-0.3 M) was found to affect the protopectinase activity (response variable) after 24 hr of cultivation. In the range studied, ISP and glucose had a negative effect on the response variable, whereas phosphate had a positive effect. A statistically significant interaction was identified between phosphate and ISP, suggesting that correct optimization of medium formulation in this case can only be obtained using factorial design of experiments. Protopectinase activity exceeding 215 U/mL was obtained in a medium containing 4% ISP, 0.3M phosphate, and no added sugar.

A complexity analysis of a "pragmatic" relaxation method for the combinatorial optimization with a side constraint (단일 추가제약을 갖는 조합최적화문제를 위한 실용적 완화해법의 계산시간 분석)

  • 홍성필
    • Journal of the Korean Operations Research and Management Science Society
    • /
    • v.25 no.1
    • /
    • pp.27-36
    • /
    • 2000
  • We perform a computational complexity analysis of a heuristic algotithm proposed in the literature for the combinatorial optimization problems extended with a single side-constraint. This algorithm, although such a view was not given in the original work, is a disguised version of an optimal Lagrangian dual solution technique. It also has been observed to be a very efficient heuristic producing near-optimal solutions for the primal problems in some experiments. Especially, the number of iterations grows sublinearly in terms of the network node size so that the heuristic seems to be particularly suitable for the applicatons such as routing with semi-real time requirements. The goal of this paper is to establish a polynomal worst-case complexity of the algorithm. In particular, the obtained complexity bound suports the sublinear growth of the required iterations.

  • PDF

Study on the Propulsion System Integration Optimization for a Turboprop Aircraft (터보프롭 항공기 추진기관 시스템 종합 최적 설계 연구)

  • 공창덕;김진원
    • Proceedings of the Korean Society of Propulsion Engineers Conference
    • /
    • 1995.05a
    • /
    • pp.71-81
    • /
    • 1995
  • The Propulsion System Integration can be defined as the optimization technology of combining the propulsion system components with the airframe to achieve the overall aircraft misson performance goals. The disposition of propulsion system components on engine compartment enveloped by front fuselage and fire bulkhead is very restricted because of the interference with nose L/G and engine mountig strut. The design of components depends on the traditional technical data base. The engine satisfying a customer's ROC was selected among worldwide existing engines by the comparision studies of performance analysis with enigine installed effect, future growth potential, ILS, and application to aircrafts, etc. The ground test of the propulsion system integration was performed in the test cell and on the aircraft to assure the function of the components. The flight test was performed to confirm complying the performance requirements.

  • PDF

Revenue Maximizing Scheduling for a Fast Electric Vehicle Charging Station with Solar PV and ESS

  • Leon, Nishimwe H.;Yoon, Sung-Guk
    • KEPCO Journal on Electric Power and Energy
    • /
    • v.6 no.3
    • /
    • pp.315-319
    • /
    • 2020
  • The modern transportation and mobility sector is expected to encounter high penetration of Electric Vehicles (EVs) because EVs contribute to reducing the harmful emissions from fossil fuel-powered vehicles. With the prospective growth of EVs, sufficient and convenient facilities for fast charging are crucial toward satisfying the EVs' quick charging demand during their trip. Therefore, the Fast Electric Vehicle Charging Stations (FECS) will be a similar role to gas stations. In this paper, we study a charging scheduling problem for the FECS with solar photovoltaic (PV) and an Energy Storage System (ESS). We formulate an optimization problem that minimizes the operational costs of FECS. There are two cost and one revenue terms that are buying cost from main grid power, ESS degradation cost, and revenue from the charging fee of the EVs. Simulation results show that the proposed scheduling algorithm reduces the daily operational cost by effectively using solar PV and ESS.

Improved Ectoine Production from Methane by Optimization of the Bio-milking Process in Engineered Methylomicrobium alcaliphilum 20Z

  • Lee, Yun Seo;Chai, Hanyu;Cho, Sukhyeong;Na, Jeong Geol;Lee, Jinwon
    • Korean Chemical Engineering Research
    • /
    • v.60 no.3
    • /
    • pp.392-397
    • /
    • 2022
  • Methane is one of the major greenhouse gases, recently, the biotechnological conversion from methane to high-value added chemicals have emerged as an effort to reduce methane gas emission. In this study, we optimized ectoine bio-milking conditions in which cells were repeatedly used to improve intracellular and extracellular ectoine yield from methane by using Methylomicrobium alcaliphilum 20ZDP2. First, the cultivation and intracellular ectoine accumulation conditions were optimized with respect to the growth phase and medium salinity to achieve the highest yield of synthesis. Second, ectoine excretion was optimized by determining the ectoine secretion time (15 min) in appropriate medium salinity under hypoosmotic conditions (1% NaCl). Finally, bio-milking of ectoine was successfully repeated more than 10 times using M. alcaliphilum 20ZDP2, and the ectoine yield was improved up to 129.29 mg/ DCW g.

Status and Development of Aquafarm based on Digital Twin (디지털트윈 기반 아쿠아팜 동향 및 발전 방향)

  • S.Y. Lee;U.H. Yeo;(J.G. Kim;S.K. Jo
    • Electronics and Telecommunications Trends
    • /
    • v.38 no.3
    • /
    • pp.29-37
    • /
    • 2023
  • With the increasing demand for seafood and technological advancement in aquaculture, the industry has continuously grown. On the other hand, digital twins have been actively applied to various industries. Aquaculture deals with live aquatic animals that are sensitive to growth environment management. Hence, applying a digital twin to smart aquaculture may lead to a substantial economic benefit because it enables the optimization of different variables. We analyze the status of digital twin development in agriculture. The services of the aquafarm digital twin are divided into 1) data management, 2) optimization, and 3) intelligence. Standardization related to the aquafarm digital twin is also discussed. Based on the analyses, the development stage of aquafarm digital twin is defined, and directions of technology development are suggested.