• Journal of mucopolysaccharidosis and rare diseases
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• v.2 no.2
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• pp.38-40
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• 2016

Prader-Willi syndrome (PWS) is a rare genetic disorder often caused by a deletion of the chromosome 15q11-q13 region inherited from the father or by maternal disomy 15. Growth hormone deficiency with short stature, hypogonadism, cognitive and behavioral problems, analgesia, decreased gastric motility and decreased ability to vomit with hyperphagia are common in PWS leading to severe obesity in early childhood, if not controlled. The goal of this study is to investigate the effects of recombinant human GH (rhGH, henceforth designated GH) on the gene expression related to cognitive function in the brain of PWS mouse model (Snord116del). GH restored the mRNA expression level of several genes in the cerebellum. These data suggest the effect of GH on the expression of cognitive function related genes in cerebellum may provide a mechanism for the GH-induced brain function in PWS patients.

• Journal of the Korean Regional Science Association
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• v.14 no.2
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• pp.65-75
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• 1998

Education is widely recognized one of main sources for growth. This paper attempts to incorporate the general recognition into formal regional growth model. The model structure is largely neoclassical. It produces a single good with the two factors, educated labor and non-educated labor, via a constant return production migrating to the region with the higher real wage. The educated labor in a region is accumulated by two sources, migration and physical education capital, while the non-educated labor is by only migration. The paper shows that regional growth equilibrium is characterized as a saddle point. This indicates the presence of the minimum threshold size that must be overcome before a region may grow. It contrasts sharply with results obtained in regional growth models. The paper suggests that regional growth is determined less by the technical characteristics of regional production function characteristics of regional production function but by the stock combination of educated function but by the stock combination of education labor and non-educated labor. Based on this result, the impact of agglomeration economies on regional growth is explored. It is by phase diagram demonstrated that the presence of agglomeration economies do not always lead a region to growth since there still exists the minimum threshold even in the presence of agglomeration economies.

• Honam Mathematical Journal
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• v.45 no.1
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• pp.42-53
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• 2023

The main aim of this paper is to introduce the definition of 𝜑-proximate order of a meromorphic function on the complex plane. By considering the concept of 𝜑-proximate order, we will extend some previous results of Lahiri [11]. Furthermore, as an application of 𝜑-proximate order, a result concerning the growth of composite entire and meromorphic function will be given.

• KSBB Journal
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• v.13 no.6
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• pp.730-734
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• 1998

The mathematical model of specific growth rate of Saccharomyces cerevisiae ATCC 24858 is proposed as a function of sugar and ethanol concentrations by the combination of Andrew's equation and Aiba's equation. The maximum concentration of sugar Sm, which was the highest concentration of sugar not having any effect on the growth inhibition, was 150 g/L and the substrate inhibition was expressed as a function of (S-Sm). The maximum specific growth inhibition, was 150 g/L and the substrate inhibition was expressed as a function of (S-Sm). The maximum specific growth rate ${\mu}m$, Monod's constant Ks, and Andrew's inhibition constant KI were 0.49 hr-1, 19 g/L, and 139 g/L, respectively. The maximum ethanol concentration, Pm, which did not show any inhibition effect on the specific growth rate was found to be 2 g/L. Therefore, the ethanol inhibition was represented as a function of (P-Pm). The final mathematical model for the specific growth rate of the microorganism in this work is proposed as the following. And the average percent of errors between the calculated specific growth rate and the experimental values was 5.96%.

• International Commerce and Information Review
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• v.10 no.1
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• pp.329-347
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• 2008

The purpose of this study is to examine the causal relationship between the exchange rate and economic growth, and to induce policy implications. In order to test whether time series data is stationary and the model is fitness or not, we put in operation unit root test, cointegration test. And we apply Granger causality based on an error correction model. The results indicate that uni-dierctional causality between exchange rate and economic growth is detected. Exchange rate impacts on economic growth, but economic growth don't impact on exchange rate. The analysis of impulse reaction function shows that the impulse of exchange rate impacts on Korean economic growth in negative direction. We can infer policy suggestion as follows: The fluctuation of exchange rate much affects economic growth, thus we must make a stable policy of exchange rate to continue economic growth.

• The KIPS Transactions:PartD
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• v.13D no.5 s.108
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• pp.709-716
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• 2006

As the software complexity increases, the development success rate decreases and failure rate increases exponentially. The failure rate related to the software size can be described by a growth function. Based on this phenomenon, this paper estimates the development success and completion rate using the Gompertz growth function. At first, we transformed a software size of numerically suggested $10^n$ into a logarithm and kept the data interval constantly. We tried to derive a functional relationship between the development success rate and the completion rate according to the change of logarithmic software size. However, we could not find a function which can represent this relationship. Therefore, we introduced the failure rate and the cancel rate which are inverse to the development success rate and completion rate, respectively. Then, we indicated the relation between development failure rate and cancel rate based on the change of software size, as a type of growth function. Finally, as we made the Gompertz growth function with the function which describes the cancel rate and the failure rate properly. We could express the actual data suitably. When you apply the growth function model that I suggested, you will be able to get the success rate and completion rate of particular site of software very accurately.

• Journal of Korean Society for Quality Management
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• v.34 no.3
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• pp.73-78
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• 2006

In this paper, we propose a software reliability growth model based on the testing domain in the software system, which is isolated by the executed test cases in software testing. In particular, our model assumes an imperfect debugging environment in which new faults are introduced in the fault-correction process, and is formulated as a nonhomogeneous Poisson process(NHPP). Further, it is applied to fault-detection data, the results of software reliability assessment are shown, and comparison of goodness-of-fit with the existing software reliability growth model is performed.

• KDI Journal of Economic Policy
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• v.39 no.4
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• pp.25-50
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• 2017

Whereas a large variety of previous studies show mixed results regarding the relationship between public investment and economic outcome, several studies have been conducted on related issues in Korea. The present study deals with the effect of public investment in Korea on economic growth and productivity. Using administrative data, it exploits three different methodologies: the total factor productivity approach, production function approach, and stochastic frontier production function approach. The results of this study show that public investment has a statistically significant effect on economic growth. However, it contributes little to enhance productivity. It is explained that there exists inefficiency of production in the Korean economy. These findings indicate that public investment has played a central role in the direct input factor and not in indirect role in Korea. Thus, it is necessary for public investment policies to concentrate on enhancing the efficiency of the Korean economy.

• Clinical and Experimental Pediatrics
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• v.52 no.2
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• pp.142-151
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• 2009

The incidence of small for gestational age (SGA) births is frequent, accounting for 2.3% to 8% of all live births. Several childhood and adult diseases are related to early postnatal growth and birth size, and 10% of children born SGA may have a short stature throughout postnatal life. Additionally, they may have abnormal growth hormone (GH)-insulin like growth factor axis, HPA axis, and gonadal function. Permanent changes are detrimental in an environment of nutritional abundance, and predispose SGA children to an array of diseases in adolescence and adulthood. Such changes may also cause premature pubarche, adrenarche, and precocious puberty. The varying results from clinical studies necessitate more prospective case control studies. Reproductive tract abnormalities and reproductive dysfunction are related to SGA births. GH treatment is required for SGA infants who do not experience catch-up growth.

• Journal of the Korean Society of Tobacco Science
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• v.3 no.2
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• pp.109-114
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• 1981

This experiment was conducted with three varieties (Hicks, Burley 21, Sohyang) and cropping systems (Improved mulching, Mulching, Non mulching) of NC 2326 to analyze growth kinetics by means of growth function involving its velocity and accelerated velocity. The basic growth data were obtained by harvest method at interval of ten days from transplanting to hundred days and analyzed by , regression equation, determinant of matrix, and differentiation. The plot of total dry weight of leaves, stalk and roots per a plant vs. time forms a sigmoid curve and its function fitted logistic satisfactorily. Tobacco plant grows at an accelerated velocity. And growth velocity, symmetric about an inflection point, is proportional to biomass attained and to the difference between biomass attained and the maximum, and to the decrease according to the biomass. Of varieties and cropping systems, the most maximum velocity was 9.58g per day per plant in mulching cultivation of NC 2326 and maximum accelerated velocity was 264mg per $day^2$ per plant in Burley 21.