• Proceedings of the PSK Conference
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• 2002.10a
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• pp.328.3-329
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• 2002

A convenient bioassay of nerve growth factor(NGF) is essential for assessing its potency during the course of product development and quality controls afterwards. We have set up a cell-based bioassay for determining the potency of recombinant NGF using rat pheochromocytoma (PC12) cells. Cell survival was measured by monitoring the reduction of the alamarBlue$^{TM}$ dye by living cells. (omitted)d)

• The Korean Journal of Food And Nutrition
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• v.34 no.6
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• pp.568-575
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• 2021

The purpose of this study was to investigate the effects of extract mixture of C. wilfordii and P. umbrosa (IPLUS-CWPU) on bone growth in 4-week old young male SD rats. To confirm the effect of IPLUS-CWPU, we measured the length of bone growth plate, the ratio of proliferative zone to the length of growth plate and the expression level of insulin-like growth factor, IGF-1. The IPLUS-CWPU treatment shows a significant increase of tibial and femoral growth plate and the ratio of proliferative zone in growth plate. Especially, the length increased by 13.9% and 25.3% in the tibia and femur, respectively, in the high-dose group compared to the normal group. Moreover, the expression of IGF-1 gene in liver was upregulated in IPLUS-CWPU treated groups. These results indicated that IPLUS-CWPU administration could increase the proliferative zone of bone growth plate in early developmental stage by upregulation of IGF-1 gene.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.10
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• pp.2391-2397
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• 1993

The distribution of fatigue crack growth rate is influenced by the measuring interval and methods of calculation of crack growth rate. The purpose of this paper is to suggest a method for the evaluation of crack growth rate distribution without the influence. The constant ${\Delta}P$ test and the constant .DELTA.K test are executed by using the CT specimen. The measuring interval of (${\Delta}a$/W=0.0067~0.014) crack length is not affected by methods of the calculation of the fatigue crack growth rate is suggested.

• Journal of Food Hygiene and Safety
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• v.26 no.2
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• pp.120-124
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• 2011

Predictive mathematical models were developed for predicting the kinetics of growth of Listeria monocytogenes in smoked salmon, which is the popular ready-to-eat foods in the world, as a function of temperature (4, 10, 20 and $30^{\circ}C$). At these storage temperature, the primary growth curve fit well ($r^2$=0.989~0.996) to a Gompertz equation to obtain specific growth rate (SGR) and lag time (LT). The Polynomial model for natural logarithm transformation of the SGR and LT as a function of temperature was obtained by nonlinear regression (Prism, version 4.0, GraphPad Software). Results indicate L. monocytogenes growth was affected by temperature mainly, and SGR model equation is $365.3-31.94^*Temperature+0.6661^*Temperature^{\wedge^2}$ and LT model equation is $0.1162-0.01674^*Temperature+0.0009303^*Temperature{\wedge^2}$. As storage temperature decreased $30^{\circ}C$ to $4^{\circ}C$, SGR decreased and LT increased respectively. Polynomial model was identified as appropriate secondary model for SGR and LT on the basis of most statistical indices such as bias factor (1.01 by SGR, 1.55 by LT) and accuracy factor (1.03 by SGR, 1.58 by LT).

• Journal of the Korean Society of Safety
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• v.17 no.4
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• pp.5-10
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• 2002

For fitness-for-service evaluation of high temperature plant components with defects, crack growth life must be assessed properly as indicated in the recent draft of API 579 code. Type 308 stainless steel has been widely used as a field weld material in the petrochemical industry. In this study, creep crack data of type 308 stainless steel are collected and re-analyzed using $C_t$ as a characterizing fracture parameter. A unique da/dt versus $C_t$ relationship was obtained despite of difference of creep deformation constant of the reviewed materials and specimen geometry of the tested specimens. The obtained results can be employed for crack growth life assessment and fitness-for-service evaluation for the cracks in high temperature components. It is also argued that since the effect of creep properties and other material variability on the creep crack growth behavior would be minor the obtained model may be applied for most of the 308 stainless steels.

• Journal of Interdisciplinary Genomics
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• v.5 no.2
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• pp.18-23
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• 2023

Conventional evaluation method for identifying the organic cause of short stature has a low detection rate. If an infant who is small for gestational age manifests postnatal growth deterioration, triangular face, relative macrocephaly, and protruding forehead, a genetic testing of IGF2, H19, GRB10, MEST, CDKN1, CUL7, OBSL1, and CCDC9 should be considered to determine the presence of Silver-Russell syndrome and 3-M syndrome. If a short patient with prenatal growth failure also exhibits postnatal growth failure, microcephaly, low IGF-1 levels, sensorineural deafness, or impaired intellectual development, genetic testing of IGF1 and IGFALS should be conducted. Furthermore, genetic testing of GH1, GHRHR, HESX1, SOX3, PROP1, POU1F1, and LHX3 should be considered if patients with isolated growth hormone deficiency have short stature below -3 standard deviation score, barely detectable serum growth hormone concentration, and other deficiencies of anterior pituitary hormone. In short patients with height SDS <-3 and high growth hormone levels, genetic testing should be considered to identify GHR mutations. Lastly, when severe short patients (height z score <-3) exhibit high levels of prolactin and recurrent pulmonary infection, genetic testing should be conducted to identify STAT5B mutations.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.34 no.4
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• pp.51-56
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• 2016

Old-growth and giant tree is a nonrenewable resource with great value. The purpose of this study is to provide scientific and reasonable evaluations for the preservation and management of the old-growth and giant tree. Until now the research of old-growth and giant tree's value evaluation and authoritative index is so insufficient and imperfection. Combining with the particularity of the old-growth and giant tree, this study analyzed the main value factors of the old-growth and giant tree and objectively selected the evaluation indicators. According to the actual situation value appraisal model of the old-growth and giant tree was builded. The main value factors can be divided into economic value, cultural history, growing place, tree state, tree form, tree vigor, protection level, growth environment, tree species, tree canopy, and so on. The evaluate indicators can be selected and the indicators' weight can be calculate using analytic hierarchy process methods(AHP). Based on economic value and indicators' weight, tree's total value can be revealed. After calculation and analysis, Gyeongju Gyerim Zelkova serrata's value evaluation results is 491,503,300 won. The research results of this study can provide scientific basis and reference to the old-growth and giant trees' value appraisal and loss compensation, and arouse people's environmental awareness.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.43 no.2
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• pp.65-71
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• 2020

Worldwide plant market keeps maintaining steady growth rate and along with this trend, domestic plant market and its contractors also maintain such growing tendency. However, in spite of its external growth, win-win growth of domestic material industry that occupies the biggest share in plant industry cost portion is extremely marginal in reality. Domestic plant material suppliers are required to increase awareness of domestic material brand by securing quality and reliability of international standard through improvement of design quality superior to that of overseas material suppliers. Improvement of design quality of plant material becomes an essential element, not an option, for survival of domestic plant industry and its suppliers. Under this background, in this study, priority and importance by each evaluation index was analyzed by materializing plant design stage through survey of experts and defining evaluation index by each design stage and based on this analysis result, evaluation index of stage-gate based decision-making process that may improve design quality of plant material was suggested. It is considered that by utilizing evaluation index of stage-gate based decision-making process being suggested in this study, effective and efficient decision-making of project decision-makers would be enabled and it would be contributory to improve design quality of plant material.

• The Korean Journal of Franchise Management
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• v.13 no.1
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• pp.1-17
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• 2022

Purpose: In this study we aim to identify factors affecting successful inter-firm collaboration. We tried to find out whether government subsidies to small-business owners should be made to experienced and competent cooperatives or to cooperatives with potential even if inexperienced. Research design, data and methodology: Using analytic hierarchy process (AHP), we examine if evaluation criteria for the Small Business Collaboration Grant (SBCG) reflect the potential of successful collaboration of applicant cooperatives. Results: We found that experts tend to think that applicant cooperatives without any experience as a recipient for the SBSG need to be evaluated by their growth potential and their preparation of the application rather than by their business performance or achievement history. The weight of the evaluation must be different between the growth potential and the achievements already achieved. By means of an expert survey, we confirmed that Rookies should weigh evaluation indicators that can reflect their growth potential, and experienced groups should give weight to evaluation indicators that can reflect their achievements. Conclusions: For SBCG applicants with experiences, experts tend to weigh more on SBCG business performances and feasible sharing systems. The screening procedure for the first applicant cooperatives need to focus more on "partner selection" stage, whereas elements related to "realization" apply to experienced applicant cooperatives.

• 한국초전도학회:학술대회논문집
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• 2009.07a
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• pp.108-108
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• 2009