• Transactions of the Korean Society of Mechanical Engineers
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• v.13 no.2
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• pp.252-256
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• 1989

In the low cycle fatigue fracture testing with KS(or JIS) SS41, crack growth rate, AE count rate and J-integral range are measured to get empirical relations between crack growth rate and J-integral range, AE count rate and J-integral range as well as AE count rate and crack growth rate. All the relations are shown to be linear on the log-log graphs. It is also shown that the linear relations can be formulated by using Dunegan's assumption and elastic-plastic fracture mechanics along with the well-known relation of crack growth rate and J-integral range. It is concluded that the differences between experimental and theoretical values are due to Dunegan's assumption.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.674-682
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• 2011

The present study was undertaken to investigate the effect of acupuncture & moxibustion therapy on the hair follicle growth of skin 5 days and 10 days by macroscopic, microscopic and immunohistochemical methods. The results were as follows : Macroscopic hair follicle growth of plum-blossom needle treated group and strong moxibustion treated group was more increase than that of control group. Microscopic hair follicle growth of plum-blossom needle treated group and strong moxibustion treated group was hair growing cycle, anagen phase VI and that of control group and weak moxibustion treated group was hair growing cycle, anagen phase IV. Immunohistochemical observations on the expression of various growth factors, enzyme and receptor in hair follicle cycle after local treatment of acupuncture & moxibustion therapy are as follows: Expression of fibroblast growth factor was more intense in epidermis in plum-blossom needle treated group, epidermis and secondary hair germ cells in strong moxibustion treated group than control group. Expression of epidermal growth factor was more intense in epidermis in all experimental groups, and secondary hair germ cells in moxibustion treated group than control group. Expression of c-kit receptor was more intense in epidermis, secondary hair germ cells, outer root sheath in all experimental groups than control group. Expression of protein kinase C-${\alpha}$ was more intense in epidermis, secondary hair germ cells, outer root sheath in all experimental groups than control group. Expression of vascular endothelial growth factor was more intense in epidermis, bulge, secondary hair germ cells, outer root sheath in plum-blossom needle treated group and strong moxibustion treated group than control group. We concluded that acupuncture & moxibustion therapy related to the expression of various growth factors, enzymes and receptor on the hair growth cycle for hair growth.

• KDI Journal of Economic Policy
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• v.31 no.2
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• pp.47-85
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• 2009

With a relatively simple quantitative method, this study comprehensively analyzes the characteristics related to business cycles represented by macroeconomic variables of Korea since 1970. This empirical analysis deals with roughly following three topics: How to identify cyclical component with respect to trend; with what characteristics and how the economic variables of each sector move with in the phases of business cycle, and; whether there are signs of a structural change in the phases of business cycle. Section 2 discusses how to identify trends and cycle components, the basis assumption for the analysis of business cycle. Like the Korean economy, where a relatively high growth rate has been maintained, it is appropriate to determine its economic recession based on the fall in the growth trend, not in the absolute level of real output. And, it is necessary to apply the concept of growth cycle against a traditional concept of business cycle. Accordingly the setting of growth trend is of preliminary importance in identifying cyclical fluctuations. The analysis of Korea's GDP data since 1970, the decomposition of trends and cycles through the Band-pass filter is found to appropriately identify the actual phases of busyness cycle. Section 3 analyzes what particular relationship various economic variables have with output fluctuations during the phases of economic cycle, using the corss-correlation coefficients and prediction contribution. Section 4 monitors the stability of the phases of Korea's business cycle and quantitatively verifies whether there is a structural break, and then reviews the characteristics of variations in each sector. And, stylized facts observed through these studies are summarized in the conclusion. The macroeconomic stability of Korea, in particular, is found to continue to improve since 1970, except for the financial crisis period. Not only that, it is found that its volatility of economic growth rate as well as inflation have been reduced gradually. Meanwhile, until recently since 2000, the volatility in domestic demand has remained stable, while that in exports and imports has been increased slightly. But, in an over all perspective, Korea's business cycle variation is on the decline due to shorter response period to shocks and the formation of complementary relationship among economic sectors.

• Journal of Distribution Science
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• v.11 no.2
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• pp.5-10
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• 2013

Purpose - The current research examines the effect of life cycle stages on capital structure of listed companies in Tehran Stock Exchange. Research design, data, methodology - By aid of 685 year-company data, which collected from financial statements of companies during 2006-2012, first, the companies, are classified into three groups including companies in growth, maturity and decline stages. After removing the companies, which were not in accordance with life cycle model, 86 companies were selected to test two main hypotheses of the research. Results - The results show that the capital structure of the sample companies is different in various life cycle stages. More investigation by LSD test also revealed that the total debt to total assets ratio means of the companies in growth stages were significantly different from those companies in maturity stages and those in growth stages had high level of debt to assets ratio. Conclusions - The result showed the average amount of the working capital for companies in three stages are significantly different and due to high level of operation of the companies in maturity and decline stages, these companies held high amount of working capital than those in the growth stages.

• Clinical and Experimental Reproductive Medicine
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• v.20 no.2
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• pp.131-135
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• 1993

The ultrasonographic examination with vaginal probe(5MHz) was undertaken in 101 patients at infertility clinic of Eul-Ji General Hospital. This study was performed to evaluate the number of mature follicles per menstrual cycle, the relationship of both ovaries for consecutive ovulatory cycle and the responsiveness of follicular growth followed by administration of ovulation inductant. The results were as follows; 1. The ovulation induction group with clomiphene citrate showed more follicles than natural menstrual cycle group. 2. Each means of numbers of follicles between ovaries showed no difference between natural and ovulatory induction groups. 3. The rate of follicular growth per one menstrual cycle showed higher in the clomiphene citrate induced cycle group. 4. Clomiphene citrate induced group tends to be easier for multiple follicular growth but had no significant difference in statistics. 5. The ipsilateral Vs. contralateral follicular growth rate for consecutive menstrual cycles in both ovaries showed no significant difference between two groups.

• Advanced Composite Materials
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• v.16 no.2
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• pp.151-166
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• 2007

High-cycle fatigue characteristics of quasi-isotropic carbon fiber reinforced plastic (CFRP) laminates [-45/0/45/90]s up to $10^8$ cycles were investigated. To assess the fatigue behavior in the high-cycle region, fatigue tests were conducted at a frequency of 100 Hz, since it is difficult to investigate the fatigue characteristics in high-cycle at 5 Hz. Then, the damage behavior of the specimen was observed with a microscope, soft X-ray photography and a 3D ultrasonic inspection system. In this study, to evaluate quantitative characteristics of both transverse crack propagation and delamination growth in the high-cycle region, the energy release rate associated with damage growth in the width direction was calculated. Transverse crack propagation and delamination growth in the width direction were evaluated based on a modified Paris law approach. The results revealed that transverse crack propagation delayed under the test conditions of less than ${\sigma}_{max}/{\sigma}_b$ = 0.3 of the applied stress level.

• Korean Journal of Metals and Materials
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• v.47 no.7
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• pp.391-396
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• 2009

Tensile, low cycle fatigue, and fatigue crack growth rate tests were conducted at RT and $300^{\circ}C$ for type 304 stainless steel. Tensile was tested under displacement control and low cycle fatigue was tested under strain control. Fatigue crack growth rate test was conducted under load control and crack was measured by DCPD method. Yield strength and elongation decreased at $300^{\circ}C$. Dynamic strain aging was not detected at $300^{\circ}C$. Low cycle fatigue life increased but fatigue strength decreased at $300^{\circ}C$. Fatigue crack growth rate increased at $300^{\circ}C$. Dislocation structures were mixed with cell and planar and did not change with temperature. Grain size did not change but plastic strain increased at $300^{\circ}C$. Strain induced martensite after low cycle fatigue test increased at RT but decreased at $300^{\circ}C$. It was concluded that the increase of low cycle fatigue life at $300^{\circ}C$ was due to the decrease of strain induced martensite at which crack was initiated.

• Journal of Ocean Engineering and Technology
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• v.11 no.3
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• pp.76-88
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• 1997

Constant .DELTA.K fatigue crack growth rate experiments were performed by applying an intermediate single and multiple overload for structural steel, SM45C. The purpose of the present study is to investigate the influence of multiple overloads at various stress intensity factor ranges and the effect of statistical variability of crack retardation behavior. The normalized delayed load cycle, delayed crack length and the minimum crack growth rate are increased with increasing baseline stress intensity factor range when the overload ratio and the number of overload application were constant. The crack retardation under low baseline stress intensity factor range increases by increasing the number of overload application, but the minimum crack growth rate decreases by increasing the number of overload application. A strong linear correlation exists between the minimum crack growth rate and the number of overload applications. And, it was observed that the variability in the crack growth retardation behavior are presented, the probability distribution functions of delayed load cycle, delayed crack length and crack growth life are 2-parameter Weibull. The coefficient of variation of delayed load cycle and delayed crack length for the number of 10 overload applications data are 14.8 and 9.2%, respectively.

• Journal of Industrial Technology
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• v.22 no.A
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• pp.3-8
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• 2002

In this study, extremely low cycle fatigue tests were carried out under push-pull loading conditions using graphite cast iron (GCD). In order to clarify the fatigue fracture mechanism of GCD in an extremely low cycle fatigue regime successive observations of internal fatigue damage were performed. The results obtained are as follows. (1) The process of extremely low cycle fatigue can be classified into three stages which are composed of the generation, growth and coalescence of microvoids inside materials. (2) In an extremely low cycle fatigue regime, microvoids originate from debonding of graphite-matrix interface.

• The Korean Journal of Physiology and Pharmacology
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• v.16 no.3
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• pp.153-158
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• 2012

Cellular effects of ethanol in YD-15 tongue carcinoma cells were assessed by MTT assay, caspase activity assay, Western blotting and flow cytometry. Ethanol inhibited the growth and proliferation of YD-15 cells in a dose- and time-dependent manner in an MTT assay. The effects of ethanol on cell cycle control at low percent range of ethanol concentration (0 to 1.5%), the condition not inducing YD-15 cell death, was investigated after exposing cells to alcohol for a certain period of time. Western blotting on the expression of cell cycle inhibitors showed that p21 and p27 was up-regulated as ethanol concentration increases from 0 to 1.5% whilst the cell cycle regulators, cdk1, cdk2, and cdk4 as well as Cyclin A, Cyclin B1 and Cyclin E1, were gradually down-regulated. Flow cytometric analysis of cell cycle distribution revealed that YD-15 cells exposed to 1.5% ethanol for 24 h was mainly arrested at G2/M phase. However, ethanol induced apoptosis in YD-15 cells exposed to 2.5% or higher percent of ethanol. The cleaved PARP, a marker of caspase-3 mediated apoptosis, and the activation of caspase-3 and -7 were detected by caspase activity assay or Western blotting. Our results suggest that ethanol elicits inhibitory effect on the growth and proliferation of YD-15 tongue carcinoma cells by mediating cell cycle arrest at G2/M at low concentration range and ultimately induces apoptosis under the condition of high concentration.