• Clinical and Experimental Pediatrics
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• v.61 no.3
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• pp.78-83
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• 2018

Purpose: Frequent desaturation due to immature incoordination of suck-swallow-breathing in preterm infants can influence multiple organs such as the heart, lungs, and brain, which can then affect growth and development. Most notably in preterm infants, feeding desaturation may even affect pulmonary function during gavage feeding. Because respiratory muscle activities may reflect the work required during respiration, we evaluated the differences in these activities between full-term and preterm infants with feeding desaturation, and investigated the correlations with clinical variables. Methods: Nineteen preterm infants with feeding desaturation (group 1) and 19 age-matched full-term infants (group 2) were evaluated. Oromotor function was evaluated using video recording. The root-mean-square (RMS) envelope of the electromyography signal was calculated to quantify the activities of muscles involved in respiration. The differences in RMS between both groups and the correlation with clinical variables including gestational age (GA), birth weight (BW), and Apgar scores (AS) at 1 and 5 minutes after birth were evaluated. Results: The RMS values of the diaphragm (RMS-D) and rectus abdominis (RMS-R) were significantly greater in group 1 compared to group 2, and the 1- and 5-min AS were significantly lower in group 1 compared to group 2. RMS-D and RMS-R were inversely correlated with GA, BW, 1- and 5-min AS in all infants. Conclusion: This study showed that respiratory muscle activities were augmented during feeding in preterm infants compared to full-term infants. Additionally, respiratory muscle activities were inversely correlated with all clinical variables.

• Journal of the Korea Furniture Society
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• v.20 no.4
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• pp.317-325
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• 2009

On the ground of that toy as for infants is an important tool for education as well as play and furthermore it has a great influences on their growth and development, the present study intends to analyze the characteristics of the infant-oriented toys made of wood, the environment-friendly material. Object of the study includes the infants aged 2 to 7, and the wooden toy not only in domestic also international cases are investigated and analyzed from the point of function and design in particular, and the infant-oriented wooden toy is finally characterized. The wooden toys are classified in 5 items according to functions. There are toy helping a physical development like small muscles, toy improving the creativity, toy assisting language learning like Korean & English, toy contributing to number understanding and counting, and toy for imitation of social roles. The characteristics of the wooden toy are that the natural color & grain of wood are shown first, and also the natural texture & aroma of wood are felt secondly, and geometric design and shape are often presented thirdly, and recycling is available fourthly, and it is expensive finally. In order to revitalize the wooden toys lagging behind the cheap and diverse toys made of plastic, it is highly needed that development of the environment-friendly painting, unique design, marketing strategy of enterprises and use of domestic wood material.

• Clinical and Experimental Pediatrics
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• v.54 no.9
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• pp.368-372
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• 2011

Necrotizing enterocolitis (NEC) is one of the most critical morbidities in preterm infants. The incidence of NEC is 7% in very-low-birthweight infants, and its mortality is 15 to 30%. Infants who survive NEC have various complications, such as nosocomial infection, malnutrition, growth failure, bronchopulmonary dysplasia, retinopathy of prematurity, and neurodevelopmental delays. The most important etiology in the pathogenesis of NEC is structural and immunological intestinal immaturity. In preterm infants with immature gastrointestinal tracts, development of NEC may be associated with a variety of factors, such as colonization with pathogenic bacteria, secondary ischemia, genetic polymorphisms conferring NEC susceptibility, anemia with red blood cell transfusion, and sensitization to cow milk proteins. To date, a variety of preventive strategies has been accepted or attempted in clinical practice with regard to the pathogenesis of NEC. These strategies include the use of breast feeding, various feeding strategies, probiotics, prebiotics, glutamine and arginine, and lactoferrin. There is substantial evidence for the efficacy of breast feeding and the use of probiotics in infants with birth weights above 1,000 g, and these strategies are commonly used in clinical practice. Other preventive strategies, however, require further research to establish their effect on NEC.

• Child Health Nursing Research
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• v.22 no.4
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• pp.326-335
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• 2016

Purpose: It is crucial to provide adequate enteral nutrition for postoperative recovery, wound healing and normal growth in infants in pediatric cardiac ICUs. This study was done to develop a feeding protocol using the vaso-active inotropic (VAI) score and to evaluate the impact of nutritional outcomes following the new feeding protocol for infants who underwent cardiac surgery. Methods: This study consisted of three phases. First, a feeding protocol was developed based on a literature review. Second, ten experts rated the content validity. Third, a comparison study was conducted to evaluate the impact of the new feeding protocol. Data were analyzed using SPSS Version 20. Results: Twenty-nine infants were enrolled in the pre-protocol group, and 22 infants in the post-protocol group. Patients in the 2 groups were similar. Time to reach feeding goal was significantly decreased from 56.0 (27-210) hours to 28.5 (10-496) hours in the post-protocol group (Z=-4.22, p<.001). Level of enteral feeding knowledge among nurses increased significantly after implementation of the protocol. Conclusion: The feeding protocol using VAI score facilitates the achievement feeding goal to decrease feeding interruptions and help nurses in their practice. Larger studies are necessary to examine clinical outcomes following the implementation of this feeding protocol.

• Journal of Nutrition and Health
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• v.30 no.5
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• pp.478-488
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• 1997

Omega-3 fatty acid, docosahexaenoic acid(DHA) is found in a high proportion in the structural lipids of cell membranes, in particular those of the central nervous system and the retina. Diet-induced changes in fatty acid composition in these tissues may affect physiochemical functions. This study was conducted to investigate whether supplements of DHA in infant formula has an effect on the composition of fatty acids in erythrocytes with regard to brain development. Experimental groups were breastmilk group(n=21), placebo formula group(n=15), and DHA supplemented formula (0.26%) group(n=16). Infants were selected by mothers who deliverecdd at Kyung Hee medical center from February to April, 1996. Infant body weight, length, and head circumference were similar among the experimental groups at 16 weeks of age. The levels of DHA in breastmilk, placebo formula, and DHA supplemented formula were 0.56, 0, and 0.26% of total fatty acids, respectively. There was a significant correlation between dietary DHA intake and erythrocyte DHA levels. The levels of arachidonic acid did not differ among the three expermental groups. The result of flash visual evoke potential(VEP) test was correlated with the erythrocyte levels and dietary DHA levels at 16 weeks of age. No other fatty acid was correlated with VEP test results. No differences were found in Bayley Mental and Psychomotor Development Index scores among the three groups at 20 weeks of age. DHA seems to be an essential nutrient for optimum growth and maturation of term infants. Relatively small amounts of dietary DHA supplementation significantly elevate DHA supplementation significantly elevate DHA content in erythrocytes, which in turn has an implication for better scores for infant's VEP test. Whether supplementation of formula-fed infants with DHA has long-term benefits remains to be elucidated.

• Child Health Nursing Research
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• v.15 no.1
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• pp.34-41
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• 2009

Purpose: In this study, a Checklist for Infant and Child Developmental Screening (CICDS) was designed for use by primary pediatric health care providers to identify infants and children with developmental delays. Method: Each Item of the CICDS was constructed referring to existing tools. In 5 public health centers of B city, 500 infants and children were selected at the age of 2, 4, 6, 12, & 18 months and assessed between October and December 2006, CICDS and the Korea Denver II were compared to assesses the validity of the CICDS. Results: The CICDS consisted of 30 items in 4 areas; Personal-social, Fine motor-adaptive, Language, Gross motor. The results of the CICDS correlated significantly with the result of Korea Denver II at each month of age. (r=0.19; p<.01). Of the 500 infants and children, 148 were "suspect" for development delays (sensitivity of 96%, specificity 73%). On the CICDS, 74.6% of children received same result as Denver II. In discriminant analysis, 89.9% of children were identified correctly by CICDS (p<.01). Conclusion: CICDS could be a screening procedures to quickly and reliably identify infants with developmental delays. It also provides a mean of recording measurements of development characteristics.

• Clinical and Experimental Pediatrics
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• v.49 no.1
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• pp.29-33
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• 2006

Purpose : The aim of this study was to analyze the results and contributing factors of catch-up growth in very low birth weight infants(VLBWI) at the corrected age of 2 years. In addition, we looked for a relationship between the catch-up growth and the development by the bayley scales of infant development II(BSID II). Methods : A retrospective analysis by evaluating medical records was done for the 76 VLBWI whose follow-up was possible up to a corrected age of 2 years, out of the 114 who had been treated in the neonatal intensive care unit during the January of 2000 to December of 2001 at Samsung Cheil Hospital. Based on the Standard Korean Infant's Growth Curve, the catch-up growth group was defined over the 10th percentile of weight at 2 years as the corrected age and the failed catch-up growth group was defined under the 10th percentile. We investigated the clinical factors and courses of each group and compared the scores of the BSID II. Results : The catch-up growth group of the VLBWI was 51 infants and the failed catch-up growth group was 25 infants. In comparison with maternal clinical factors, use of antenatal steroids was significantly higher in the catch-up growth group. In comparisn with clinical factors and courses of VLBWI, two clinical factors were significantly different between the two groups : birth weight and intrauterine growth retardation(IUGR). Numbers of delayed development were increased in the failed catch-up growth group but statistically significant differences could not be observed. Conclusion : The catch-up growth of the VLBWI was affected by the use of antenatal steroids, birth weight and IUGR. No significant differences regarding neurodevelopmental outcome were observed between the catch-up and failed catch-up growth groups.

• Korean Parent-Child Health Journal
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• v.16 no.1
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• pp.17-26
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• 2013

Purpose: This study was to examine the mother's knowledge of premature development and rearing and their education needs in order to provide information to develop an education program for premature mothers. Methods: The study participants was 73 mothers of premature infants. Knowledge on premature infant's development and rearing was measured by measurement tools developed by previous research. The education needs about development and rearing were measured by self-report questionnaire. The data were analyzed using descriptive statistics, t-Test, ANOVA using SPSS 20.0. Results: The score of knowledge on development was 59.3 out of 100. The category of knowledge on language development was rated the highest, and motor development category was the lowest. The score of knowledge on rearing was 77.8 out of 100. The knowledge on bathing category was rated the highest and defecation category was the lowest. The growth education needs for premature infant development was the highest education needs of premature infant development. The method for developmental improvement was the highest education needs of premature infant rearing. Conclusion: The results showed that premature infant mothers have less knowledge on premature development than premature rearing, also mothers were interested in development and there were many needs on premature infant's development.

• Clinical and Experimental Pediatrics
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• v.57 no.3
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• pp.117-124
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• 2014

Purpose: Administration of antiretroviral drugs to mothers and infants significantly decreases mother-to-child human immunodeficiency virus (HIV) transmission; cesarean sections and discouraging breastfeeding further decreases this risk. The present study confirmed the HIV status of babies born to mothers infected with HIV and describes the characteristics of babies and mothers who received preventive treatment. Methods: This study retrospectively analyzed medical records of nine infants and their mothers positive for HIV who gave birth at Korea University Ansan Hospital, between June 1, 2003, and May 31, 2013. Maternal parameters, including HIV diagnosis date, CD4+ count, and HIV ribonucleic acid (RNA) copy number, were analyzed. Infant growth and development, HIV RNA copy number, and HIV antigen/antibody test results were analyzed. Results: Eight HIV-positive mothers delivered nine babies; all the infants received antiretroviral therapy. Three (37.5%) and five mothers (62.5%) were administered single- and multidrug therapy, respectively. Intravenous zidovudine was administered to four infants (50%) at birth. Breastfeeding was discouraged for all the infants. All the infants were negative for HIV, although two were lost to follow-up. Third trimester maternal viral copy numbers were less than 1,000 copies/mL with a median CD4+ count of $325{\mu}L$ ($92-729{\mu}L$). Among the nine infants, two were preterm (22.2%) and three had low birth weights (33.3%). Conclusion: This study concludes that prophylactic antiretroviral therapy, scheduled cesarean section, and prohibition of breastfeeding considerably decrease mother-to-child HIV transmission. Because the number of infants infected via mother-to-child transmission may be increasing, studies in additional regions using more variables are necessary.

• Journal of the Korean Institute of Rural Architecture
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• v.15 no.4
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• pp.9-16
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• 2013

The purpose of this study is presented playground space for early childhood facilities. Describes whether any development of children, and how to respond in accordance with each of the activities. The infants and toddlers life cycle is a continuation of play. Toddlers to play is the essence of life itself, through play, the world embracing and digestive, raising ideas and emotions expressed through play. It is time that paves the growth of infants age children. And equipped with personality, values, emotions, attitudes, play a very important role in this process. Play it delivers, it can not learning education. Sympathetic and experience through play, and be equipped to allow the personality, social, physical. So, we have an obligation required to provide adequate facilities and play so that children can grow properly. In this paper, from the limited play space and is listed on the importance alive to give the children a sense of space to get the sympathetic. And, analysis shown about affect for children each play, and space. In this paper, we performed a study is Performed a case studies of and domestic kindergarten and foreign kindergarten where the differences between the various lists and how to derive a plan for solving the problem by comparison and analysis were performed.