• Journal of Korean Academy of Nursing
• /
• v.32 no.4
• /
• pp.550-559
• /
• 2002

This study was conducted to determine whether low intensity regular exercise following dexamethasone treatment could attenuate steroid-induced muscle atrophy. Method: 36 Wistar-rats(90-110g) were divided into six groups: control group(C), dexamethasone treatment group(D), sedentary group after normal sedentary period(C+S), sedentary group after dexamethasone treatment period(D+S), exercise group after normal sedentary period(C+E), and excercise group after dexamethasone treatment period(D+E). D, D+S, and D+E groups received dexamethasone injection(5mg/Kg) for seven days whereas C, C+S, and C+E groups received normal saline injection. Both C+E and D+E groups ran on a treadmill for 60 minutes/day(20minutes/4hours) at 15m/min and a 10$^{\circ}$grade for seven recovery days. Result: Post-weight(body weight before muscle dissection) of D group significantly decreased by 16.03%, and that of D+E group significantly increased by 15.51% compared with pre-weight(body weight before steroid treatment). TypeII muscle(plantaris and gastrocnemius) weights of D group were significantly lower than those of C group. Myofibrillar protein contents of typeII muscles of D group tended to decrease comparing with C group. In D+E groups, body weights and relative weights of typeII muscles(muscle weight(mg)/post-weight(g)) tended to increase comparing with D+S group. Conclusion: It is suggested that steroid- induced muscle atrophy can be ameliorated through low intensity regular exercise after dexamethasone treatment.

• Applied Microscopy
• /
• v.22 no.2
• /
• pp.46-65
• /
• 1992

In this study, we have made morphological and cytochemical observations to investigate the type of Golgi apparatus around the bile canaliculus. The animal (Wister, $220{\sim}250gm$) were divided into 4 groups; normal, hydrochol, colchicine and hydrochol-colchicine. The Golgi apparatus is classified into 16 different types from 4 different groups. In the normal group, we could observe 12 different types of the sixteen. Type I which showed convexed cisterns facing the bile canaliculi was most abundant of the types. In the hydrochol group, 14 types were observed. Type VII and type I showed convexed cisterns facing the bile canaliculus and were abundant. In the colchicine group, 11 different types were viewed and type XIV which showed intensely dilated cisterns without the polarity was predominant. In the hydrochol-colchicine group, we observed 3 different types. Type XIV clearly showed the highest percentage, although that type was less numerous in this group than in the colchicine group. In the hydrochol group, the Golgi apparatus showed a tendency to increase in numbers, while in the hydrochol-colchicine group the Golgi apparatus showed a tendency to decrease in numbers. The reactive products of thiamine pyrophosphatase and acid phosphatase were apparent over the distal Golgi cistern in the normal and hydrochol groups, but were decreased or not observed in the colchicine and hydrochol-colchicine groups. From the results, it is assumed that with the presence of the microtubule, Golgi cisterns are dilated with polarity after stimulation of secretion. Without the microtubule, the cistern becomes more intensely dilated and none polaric. Also the enzymes within the cisternal membrane become decreaed or absent and the Golgi apparatus decreases in numbers after activation of secretion.

• The Journal of Korean Obstetrics and Gynecology
• /
• v.25 no.4
• /
• pp.81-93
• /
• 2012

Objectives: A women's body type or body temperature is often thought to be associated with gynecologic disorders or dysmenorrhea. The purpose of this study is to analyse the characteristics of body type and body temperature in relation to gynecologic disorders and dysmenorrhea. Methods: We studied 40 patients visiting Kangnam Kyung-hee Medical Center from Jan. 1st, 2010 to March 31st, 2012. Body type and body temperature were compared between Gynecologic disorder group and non-Gynecologic disorder group. Body type and body temperature were compared again between Dysmenorrhea group and non-Dysmenorrhea group. SPSS 18.0 for Windows was used to analyse the data. Results: There was no statistically significance difference in body type and body temperature between Gynecologic disorder group and non-Gynecologic disorder group. Dysmenorrhea group had more developed lower body and greater temperature difference between lower abdomen and foot compared to non-Dysmenorrhea group. Conclusions: The results suggest that women with developed lower body and greater temperature difference between abdomen and lower extremity are more prone to dysmenorrhea.

• Biomolecules & Therapeutics
• /
• v.9 no.4
• /
• pp.277-281
• /
• 2001

Chromium is an essential nutrient and participates in glucose and lipid metabolism in human beings and animals. The present study was conducted to assess the effects of chromium picolinate (Cr-pic) on glucose tolerance and insulin sensitivity in type I and ll diabetic rats. The experimental groups were type I diabetic (streptozotocin-induced: 40 mg/kg, i.p.) and type II diabetic (Goto-Kakizaki rats) models. Each group was subdivided into control. low-dose and high-dose of Cr-pic treated groups. The Cr-pic was orally administered with Cr-pic (100 mg/kg for low dose group and 200 mg/kg for high dose group) for 4 weeks. And then we performed intraperitoneal glucose tolerance test (IPGTT) and insulin sensitivity test (ITT). The glucose tolerance test was carried out by inection of glucose (2 g/kg, i.p.). The peripheral insulin sensitivity test was con- ducted by injection of insulin (5 units/kg, s.c.) and glucose. We performed determining of blood glucose concentration at 0, 10, 30, 60, 90, and 120 min using automated glucose analyzer. The plasma insulin concentration was determined by rat insulin EIA kit. Administration of Cr-pic improved weight gain in all group s with higher significant in the low-dose group. There was no significance between the control and the Cr-pic treated groups in the area under the blood glucose curve and serum insulin concentration plots of IPGTT and peripheral ITT in type I diabetic rats. But Cr-pic treated groups showed significantly lower levels of the area under the blood glucose currie during IPGTT and ITT and the high-dose group showed less effects compared with the low-dose group in the type II diabetic rats. The plasma insulin concentration of both diabetic groups was not influenced by Cr-pic supplementation. We can conclude that chromium picolinate may improve the endogenous and exogenous insulin action and peripheral insulin sensitivity in type II diabetic rats.

• 한국초전도학회:학술대회논문집
• /
• v.16
• /
• pp.74-74
• /
• 2006

• Journal of Korean Biological Nursing Science
• /
• v.13 no.1
• /
• pp.1-7
• /
• 2011

Purpose: The purpose of this study was to compare the hypertrophic effects of low-intensity exercise on weight, myofibrillar protein content and Type I, II fiber cross-sectional area of hindlimb muscles of rats between every other day exercise and every day exercise. Methods: Adult male Sprague-Dawley rats were assigned to 1 of 3 groups: control group (C, n=6), experimental group 1 (E1, n=7) and experimental group 2 (E2, n=7). Rats in E1 group had 7 sessions (every other day) and those in E2 group had 14 sessions (every day) of exercise in which they ran on a treadmill for 30 min/day at 10 m/min. Results: Muscle weight, cross-sectional area of type I fiber and myofibrillar protein content of soleus and myofibrillar protein content of plantaris in E1 group, and myofibrillar protein content of soleus and cross-sectional area of type I fiber of plantaris in E2 group were greater than those in C group. Cross-sectional area of type I fiber of soleus of E1 group was higher than E2 group while cross-sectional area of type I fiber of plantaris of E2 group was higher than E1 group. Conclusion: Hypertrophy of hindlimb muscles occurs from every other day exercise similar to every day exercise.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.23 no.2
• /
• pp.347-355
• /
• 1996

The purpose of this study was to compare the bond strengths of different kinds of glass ionomer cements (GIC), which is recently increasing the clinical application in the field of pediatric dentistry and measure the repaired bond strengths in order to examine the clinical applicabilty of partial repaired cases. By using one kind of the light cured type GIC and three kinds of the chemical cured type GIC, the bond strengths of the followings were compared : unrepaired group as control, repaired conditioning group, which was treated the repaired surface using 25% polyacrylic acid and repaired non-conditioning group without surface treatment. Three point bending test was performed under Universal Testing Machine in order to measure the compressive bond strengths. The results were as follows : 1. Light cured GIC had higher bond strength than chemical cured type GIC in both of repaired and unrepaired groups. 2. In repaired cases, all of the materials decreased the bond strength when compared to the control group. In the light cured type, the bond strength of repaired conditioning group decreased 31.6%, repaired non-conditioning group decreased 40.8%. In chemical cured types, the bond strength of repaired conditining group decreased 11.8%, repaired non-conditioning group decreased 20.9%. 3. All the materials, in the case of the chemical treatment on the repaired surface using 25% polyacrylic acid had higher bond strength than untreated but, lower than control group.

• The Journal of Korean Academy of Prosthodontics
• /
• v.43 no.2
• /
• pp.258-263
• /
• 2005

Statement of problem. Implant screw loosening has been remained a problem in implant prosthodontics. The time needed to insert screw driver into abutment screw head should be shortened for the purpose of decreasing the chair time. Purpose. The purpose of this study was to investigate the effects of the design of abutment screw driver on the amount of time for insertion of screw driver into abutment screw head. Material and methods. Hexagonal and rectangular types of abutment screw drivers were used. The original abutment screw drivers were modified by grinding acute angle of the screw driver tip (modified drivers). Group 1 : hexagonal type abutment screw and original driver Group 2 : hexagonal type abutment screw and modified driver Group 3 : rectangular type abutment screw and original driver Group 4 : rectangular type abutment screw and modified driver UCLA lab analogues were located in acrylic resin block. The angulations of them were 0 and 20 degrees. The times needed for insertion were measured. Group 1 and 3 were used as controls. Results. 1. Group 2 showed shorter insertion time than group 1, regardless of implant angulations (p<.05). 2. Group 4 showed shorter insertion time than group 3, regardless of implant angulations (p<.05). Conclusion. Modified abutment screw drivers required less amount of time to insert screw driver into abutment screw head. Modification of abutment screw driver was beneficial.

• Journal of Periodontal and Implant Science
• /
• v.35 no.1
• /
• pp.31-41
• /
• 2005

Fimbriae (fimA) of Porphyromonas gingivalis are filamentous components on the cell surface and are thought to play an important role in the colonization and invasion of periodontal tissue. P. gnigivalis fimA gene encoding fimbrillin, a subunit of fimbriae, has been classified into 5 genotypes (types I to V) based on the nucleotide sequences. In the present study, we examined the prevalence of these fimA genotypes in patients with dental implant and the relationship between prevalence of these genotypes and peri-implantitis. Dental plaque specimens obtained from 80 peri-implant sulci of 50 patients with dental implants were analyzed by 16S rRNA fimA gene-directed PCR assay. P. gingivalis were detected in 74.4% of the samples of the control group (healthy peri- implant sulci; probing depth<5mm) and in 92.0% of the samples of the test group (peri-implant sulci with peri-iimplantitis; probing $depth{\geqq}5mm$). Among the P. gingivalis-positive samples of the control group, the most prevalent fimA type was type I (29.3%), followed by type II (26.8%). In contrast, a majority among the P. gingivalis-positive samples of the test group was type II (56.S%), followed by type I (43.5%). TypeII fimA genotype organisms were detected more frequently in the test group and a significant difference in the occurrence of type II was observed between test and the control groups. A correlation between specific fimA types and peri-implant health status was found in type II (OR 3.545) and only a weak relationship was revealed in typeIV(OR 3.807). These findings indicate that P. gingivalis strains that possess type II fimA are predominant in peri-implant sulci with peri-implantitis and are closely associated with peri-implant health status. P. gingivalis with type II fimA may be involved in peri-implantitis.

• Korean Journal of Applied Biomechanics
• /
• v.16 no.2
• /
• pp.45-53
• /
• 2006

The purpose of this study was to analyze exercise related mechanical variables according to performance levels and Kumi-kata types in elite judo players (G1) and non-elite judo players, namely university players (G2). To achieve this purpose, three players in G1 whose main special skill was Morote-Seoinage and three university judo players(G2) was selected as comparative group. Then they were examined for distinguishing A and B types of Kumi-kata. Analyzed variables were the time required to show skills, knee degree, elbow degree. After analysing this study, conclusions were derived as follows. 1. In total necessary time of showing skills according to group of Kumi-kata type, G2 was longer than G1 in both A type (20.9%) and B type (23.7%). In necessary time of phase, in only 3P, G1 was shorter than G2 in A type (50%) and B type (75%). There was no difference in time required of 1P and 2P according to Kumi-kata type of group and in only 3P, B type was shorter than A type in both B type (75%) of G1 and B type (50%) of G2 2 There was no difference in elbow degree of offensive arm according to group of Kumi-kata type, however in A and B types, G1 could use skills by extending in kake phase, but G2 could use skills by bending. Elbow degree of offensive arm according to Kumi-kata type of group showed difference in E1. and F2 of G1. A and B types of G1 extended elbow degree in Kake phase, but G2 bent elbow degree so exercise program which could movable range extensively in Kake phase is needed.