• Proceedings of the Ginseng society Conference
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• 1998.06a
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• pp.1-11
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• 1998

Ameliorating mechanisms of red ginseng on learning deficits were investigated in the following 3 experiments; its effects on 1) place learning deficits in aged rats and in young rats with selective hippocampal lesions (behavioral study), 2) long-term potentiation in the hippocampal formation (neuro- physiological study), and 3) ChAT (choline acetyl transferase) activity in various brain regions of aged rats (pharmacological study). In the behavioral study, first, performance in the place learning tasks were compared among 3 groups of young and aged rats; control young intact rats (10-12 week old) treated with water, aged rats (28-32 month old) treated with water, and aged rats (28-32 month old) treated with red ginseng (100 mghglday) suspended in water. Second, performance in the place learning tasks was compared among 3 groups of young rats; control intact rats treated with water, rats with bilateral hippocampal lesions treated with water, and rats with bilateral hippocampal lesions treated with red ginseng (100 mg/kg/day). Each rat in these 2 behavioral experiments was tested with the 3 types of the place learning tasks in a circular open field using intracranial self-stimulation (ICSS) as reward. The ICSS reward was delivered if the rat (1) moved distance of 100-160 cm (DMT): (2) entered an experiment-determined reward place within the open field, and this place was randomly varied in sequential trials (RRPST); or (3) entered 2 specific places, and did a shuttle behavior between the 2 places (PLT). Performance of the aged rats in the ginseng group was not significantly different from that of control young rats in ICSS (current intensity, bar press rates), DMT and RRPST. However, treatment with red ginseng significantly ameliorated place-navigation learning deficits in aged rats in the PLT. Similarly, red ginseng ameliorated learning and memory deficits in young rats with hippocampal lesions in the same tasks. In the neurophysiological study using young rats, perfusion of hippocampal slices with non-sapon in fraction of red ginseng significantly enhanced magnitudes of the long-term potentiation (LfP) in the CA3 subfield. In the pharmacological study, treatment with red ginseng did not affect ChAT activity in aged rat brain including the hippocampal formation. These results strongly suggest that red ginseng ameliorates learning and memory deficits in aged rats through actions on the CA3 subfield of the hippocampal formation, which were independent of the presynaptic components of the cholinergic system

• Journal of Digital Convergence
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• v.11 no.1
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• pp.255-265
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• 2013

This study deals with the policy proposals focusing on the addiction for the rapidly growing social media service (SNS) and its diagnosis. Researcher intends to define the SNS addiction and develops a diagnostic measure, which is a valuable subject. The reason is why the SNS becomes more convenient with prevalence of smart phones and the SNS addiction becomes enough severe to suggest internet addiction policy. Researcher presents the subjects into three parts. Firstly, the SNS addiction variables are derived and validated. Secondly, the path model between the SNS addiction variables is verified and discussed. Thirdly, researcher proposes the diagnostic results and the group comparison. Therefore, the result of this study is that the SNS addiction can be measured by the four elements, which are the failure in stopping the use of the SNS, time tolerance, living disability, withdrawal and anxiety. Researcher verifies the sequential impact of each variable and figures out the SNS addict through the presentation of a realistic measurement for the addiction index and the determination of the level of the addiction. By the above result, the researcher proposes the public relations of the government policy for the sound usage of the SNS and the self management of user. Finally, various proposed in this study will help to prevent juvenile crime, social problems in the future.

• Journal of Dental Rehabilitation and Applied Science
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• v.36 no.3
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• pp.145-157
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• 2020

Purpose: This study was to determine the possible effects of trichloroacetic acid (TCA) and epidermal growth factor (EGF) through cell survival genes of the PI3K-AKT signaling pathway when applying an hydrophobically modified glycol chitosan (HGC)-based nanocontrolled release system to human gingival fibroblasts in oral soft tissue regeneration. Materials and Methods: An HGC-based nano-controlled release system was produced, followed by the loading of TCA and EGF. The group was divided into control (CON), TCA-loaded nano-controlled release system (EXP1), and the TCA- and EGF- individually loaded nano-controlled release system (EXP2). A total for 29 genes related to the PI3K-AKT signaling pathway were analyzed after 48h of culture in human gingival fibroblasts. Real-time PCR, 1- way ANOVA and multiple regression analysis were performed. Results: Cell survival genes were significantly upregulated in EXP1 and EXP2. From multiple regression analysis, ITGB1 was determined to be the most influential factor for AKT1 expression. Conclusion: The application of TCA and EGF through the HGC-based nano-controlled release system can up-regulate the cell survival pathway.

• Strategy21
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• s.37
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• pp.65-103
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• 2015

This study is an attempt to look into the future role of the ROKN and to provide a strategic way forward with a special focus on naval strategic concept and force planning. To accomplish this goal, this research takes four sequential steps for analysis: 1) assessing the role and utility of naval power of ROKN since its foundation back in 1945; 2) forecasting features of various maritime threats to influence the security of Korea in the future directly or indirectly; 3) identifying the roles to be undertaken by future ROKN; and 4) recommending Korean way of naval force planning and the operational concept of naval power. This study seeks to show that ROKN needs comprehensive role to better serve the nation with respect to national security, national prosperity and development, and future battle-space management. To safeguard the national security of Korea, it suggests three roles: 1) national guard for the peaceful unification; 2) protector of the maritime sovereignty; and 3) suppressor to maritime threats. Three more roles are highlighted for national prosperity: 1) escort of the national economy; 2) guardian for national maritime activities; and 3) contributor to the world peace. These roles need to be closely connected with the role for the battle-space management. This paper addresses the need for a dramatic shift of the central operational domain from land to maritime in the future. This will eventually offer future ROKN a leading role for developing strategic concept and force planning rather than merely a supporting one. This study finally suggests 'balanced' strategy both in concept development and force planning. A balanced force planning is a 'must' rather than an 'option' when considering a division of function between Task Fleets and Area Fleets, constructing cutting-edge conventional forces such as Aegis destroyer, CVs, or submarines, and the mix of high-profile platform and low-profile when composing future fleets. A 'balance' is also needed in operational concept. The fleet should be prepared to fulfill its missions based on two different types of force operation i.e., coercive or cooperative application of the utility of naval force. The findings and recommendations of the study are relevant today, and will be increasingly important in the future to achieve various political goals required by enhancing the utility of naval power.

• The KIPS Transactions:PartD
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• v.16D no.5
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• pp.715-728
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• 2009

The Enterprise Service Bus based on Java Business Integration is an web service standard and one of the methods for implementing distribution channels of Service Oriented Architecture. Consisting of open source group, extensive venders and users, the ESB based JBI has the problems of ineffectiveness as well as advantages of extensibility of service plug-in. That is, in case users need to use Service plug-in, manual connection of packaging process and sequential distribution method is required. This study, therefore, proposes as a way of trouble-shooting the user-oriented component deployment tool which can manage entire process for deploying The ESB middleware platform to Service unit. At the same time, this study elicited the requirements based on issues of JBI-based ESB and has developed the modeling property, packaging, distribution and evaluation thru Schema analysis of JBI-compatible component. Using the deployment tool this study proposed, users will be able to perform and manage the whole deploying process without additional manual work for connecting component. Not only it is expected that interface based on Graphic User Interface provide usability and convenience but they can also minimize the errors rate through component and route validity verification function provided in deployment tool.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.19 no.4
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• pp.256-264
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• 2014

This study was carried out to estimate the benthic environments and polychaetous community in Garolim Bay, through five field surveys from April 2006 to April 2007. Garilim Bay is a semi-enclosed bay and composed of a biramous tidal channel and nearby wide tidal flats. Surface sediment in the inner bay was composed of fine grained particles whereas that in the mouth area of bay was of coarse grained ones. Benthic polychaete worms were the most dominant taxa occupying 65.1% of total benthic macrofauna. Species number was higher in the inner bay than mouth and outer area of bay, and in the bay higher on the tidal flat than channel area. Density was higher on the tidal flat than channel area. Dominant polychaetous species were Prionospio sp., Heteromastus filiformis, Lumbrineris longifolia and so on, which is known as opportunistic species. Prionospio sp. and H. filiformis inhabited mainly on the tidal flats in inner bay, while L. longifolia in the channel area and mouth of the bay. Cluster analysis and nMDS showed the typical inner-to-outward distribution of station groups, which indicated the sequential difference of the species composition of each station group. To assess the benthic healthiness of Garolim Bay by AMBI and BPI analysis, the benthic condition was analyzed from slightly polluted in the outer and mouth of the bay to moderately polluted in the inner bay. Assumed from dominant species composition and benthic healthiness condition, benthic environments of Garolim Bay was slightly unstable and disturbed and organic enrichment was currently underway by massed fisheries farms.

• Communications of Mathematical Education
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• v.35 no.2
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• pp.153-172
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• 2021

Various competencies such as critical thinking, systems thinking, problem solving competence, communication skill, and data literacy are likely to be required in the 4th industrial revolution. The competency regarding data literacy is one of those competencies. To nurture citizens who will live in the future, it is timely to consider research on teacher education for supporting teachers' development of statistical thinking as well as statistical knowledge. Therefore, in this study we developed and implemented a data analysis project for pre-service teachers to understand their changes in statistical knowledge in addition to their experiences of data-driven decision making process that required them utilizing their statistical thinking. We used a mixed method (i.e., sequential explanatory design) research to analyze the quantitative and qualitative data collected. The findings indicated that pre-service teachers have low knowledge level of their understanding on the relationship between population means and sample means, and estimation of the population mean and its interpretation. When it comes to the data-driven decision making process, we found that the pre-service teachers' experiences varied even when they worked as a small group for the project. We end this paper by presenting implications of the study for the fields of teacher education and statistics education.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.728-742
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• 2021

The purpose of this study was to explore the dysfunctional effects of job crafting by examining (1) the sequential dual mediating effect of work-related sense of coherence (Work-SoC) and job strain on the relationship between two dimensions of job crafting (i.e., promotion focus & prevention focus) and turnover intentions, and (2) the moderating effect of supervisor support in the relationship between each focus and Work-SoC. A total of 293 employees working at various companies in Korea participated in an online survey. The results showed that promotion-focus job crafting had a direct negative effect on turnover intention, while prevention-focus job crafting had a direct positive effect. Both promotion- and prevention-focus job crafting also had indirect effects on turnover intention by partially mediating Work-SoC and job strain. Supervisor support had a moderating effect on the relationship between prevention-focus job crafting and Work-SoC, weakening the negative effect of prevention focus on Work-SoC. The implications and future directions are discussed on the basis of the results.

• Journal of Music and Human Behavior
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• v.20 no.2
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• pp.61-88
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• 2023

This case study examined whether a cooperative musical instrument playing could enhance interactions between children with autism spectrum disorder (ASD) and their neurotypical (NT) siblings. It involved three children with ASD aged 7-12 years and three NT siblings aged 6-11 years. Each group, comprising a child with ASD and their NT sibling, participated in a 40-minute sessions twice weekly for eight sessions over four weeks. The intervention included three stages: simultaneous action, complementary action, and achieving a joint goal. Evaluation criteria included the initiation and response behaviors of each child, and sequential interactive behaviors and cooperative behaviors between pairs were measured. Additionally, before and after the intervention, parents and NT sibling assessed their perceived sibling relationships. Results showed increased interactive and cooperative behaviors. Post-intervention, both parents and NT siblings rated the sibling relationship highly, despite little change in sibling conflict and competition consciousness. These findings indicate that interactive instrument playing can enhance perceptions of siblings as cooperative play partners and aid in teaching them how to collaborate during interactions.

• Korean Journal of Culture and Social Issue
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• v.30 no.1
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• pp.1-33
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• 2024

This study analyzed the experiences of victims of state violence, discovered differences between state violence and general trauma, and proposed ways to help heal trauma. Participants were composed of state violence victims and their families in total, including 11 from the Jeju 43 Incident, 11 from the Yeos u·Sunchoen 10.19 Incident and 6 form May 18th Democratic Uprising. As a result of using the grounded theory to analyze data, a total of 170 concepts, 57 subcategories, and 20 categories were derived. The central phenomenon was direct damage caused by state violence. This included 'post-traumatic stress', 'social stigma', 'isolation from community', 'socio-economical issues' and 'family dissolution'. As a result of the process analysis, the participants experienced six phases: 'trauma', 'isolation', 'resistance', 'resignation', 'recovery', and 'growth.' Each phase is sequential but at the time mutually affect each other. Based on the results, this study verified the difference between state violence and general trauma, and emphasized social and cultural factors, such as community support, were important factors in healing state violence trauma. Besides, the implications and limitations as well as suggestions for future research were mentioned.