• Journal of Sasang Constitutional Medicine
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• v.20 no.2
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• pp.72-84
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• 2008

1. Objectives The purpose of this study was to observe the anti-oxidant effects of Hyangsayangyi-tang(HY) in SD rats. 2. Methods This experiment was used the tissue of stomach, spleen and pancreas cells of 6, 52 and 68 weeks old SD rats. Each age group was again divided into three groups. One group, as normal group, was not-treated cells, another group, as control group, was saline-treated cells, and the last group, as experimental group, was HY-treated cells. After culture for 48 hours, each groups measured the level of SOD, GSH, MDA and NO in the tissue of stomach, spleen and pancreas cells. 3. Results and Conclusions The activity of SOD were significantly increased in spleen cell of 52, 68 w-HY group, pancreas cell of 68 w-HY group and in stomach cell of 52, 68 w-HY group compared with those of the normal and the control groups. The level of GSH were significantly increased in spleen cell of 52, 68w-HY group and in pancreas cell of 68w-HY group compared with those of the normal and the control groups. The level of MDA were significantly decreased in pancreas cell of 68 w-HY group compared with those of the normal and the control groups. The level of NO were significantly decreased in spleen cell of 68 w-HY group, pancreas cell of 52, 68w-HGD groups compared with those of the control groups. According to results, HY showed anti-oxidant effect. Investigation into the clinical use of the HY is suggested for future research.

• Journal of Oral Medicine and Pain
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• v.23 no.3
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• pp.263-270
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• 1998

Considering various factors contributing oral malodor, the accurate prediction of prognosis is very important to both clinician and patients. The present study has been performed to invetigate the relationship between treatment effeicacy and pre-treatment volatile sulfur compounds (VSC) level. Ninety patients were divided into three groups, A(<150ppb), B(150< <200ppb), and C(>200ppb) groups, according to pre-treatment VSC level detected by Halimeter, and each group included 30 patients. Routine therapeutic measures for oral were provided to each patient which consisted of oral prophylaxis, tooth brushing and flossing instruction, tongue scraping by proper device, and gargling of 0.25% ZnCl2 Solution. The group with high pre-treatment VSC level (>150ppb) showed significant reduction of VSC level at 1 and 3 weeks after. However, the group with low pre-treatment VSC level (<150ppb) did not show any significant reduction during the experimental periods. Collectively, the results suggested that patients with high pre-treatment VSC level show better prognosis.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.14 no.1
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• pp.120-127
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• 2007

Purpose: This study was done to identify the level of stress, hardiness, and professional burnout of intensive care unit (ICU) nurses and to provide basic data for the qualitative improvement of nursing work achievement in the workplace. Method: The data were obtained from 129 ICU nurses through a questionnaire. Results: Stress showed positive correlation with the level of professional burnout and there was negative correlation between hardiness and professional burnout. Nurses in the group with a high level of stress, and a high level of hardiness reported a low level of professional burnout compared to those in the group with a lower level of hardiness (t=-2.60, p= .012). Nurses in the group with a low level of hardiness and a low level of stress showed a lower level of professional burnout than those with a high level of stress (t=3.51, p= .001). Conclusion: The results show that the high level of stress when coupled with a low level of hardiness of ICU nurses results in a high level of professional burnout. For this reason, it is important for nursing administration to support nurses to reduce levels of stress and the resulting burnout in ICU nurses.

• Asian Oncology Nursing
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• v.6 no.2
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• pp.152-161
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• 2006

Purpose: The purpose of this study was to investigate the effects of the information providing program of $I^{131}$ treatment on the pre-treatment anxiety and immune response of patients with thyroid cancer. Method: The used design was a nonequivalent control group design with pretest and post-test. Subjects of this study were 54 patients who had received a total thyroidectomy. They were given a information providing program with a brochure before 4 weeks of the hospitalization for $I^{131}treatment$, with problem solving phone counseling before 2 weeks of the hospitalization. Collected data were analyzed using the SPSS WIN program. Result: Hypothesis one, "The anxiety score of an experimental group would be lower than the score of a control group" was supported(t = -2.12, p = .03). Hypothesis two, "The level of cortisol of an experimental group would be lower than the level of a control group" was supported(t = -3.19, p = .00). However, hypothesis three "The level of T, B and N-K cells of an experimental group would be higher than the level of a control group" was not supported. Conclusion: The information providing program of $I^{131}$ treatment effectively decreased the anxiety of patients with thyroid cancer.

• Journal of Oriental Neuropsychiatry
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• v.19 no.3
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• pp.101-115
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• 2008

Objective: The purpose of this study was to investigate the protective effects of Sam-Jeong-Hwan(SJH) on the animal model of depression induced immobilization stress. Method: The subject were divided into 4 groups(l. normal 2. saline solution administered during immobilization stress treatment 3. SJH of 100mg/kg administered 4. BKJ of 400mg/kg administered). Immobilization stress was treated for 1 hours on day. During 2 days of immobilization stress treatment, they were executed forced swimming test, passive avoidance test, elevated plus maze test. Corticosterone and ACTH in blood were measured. Results: In forced swimming test, SJH of 400mg/kg group showed decreased immobilization. In passive avoidance test, SJH of 400mg/kg group showed increased learning execution. In EPM test, SJH of 400mg/kg group showed decreased anxiety. In locomotor activity test, SJH groups showed significantly increased locomotor activity. Stress group showed significantly increase in serum level of corticosterone, SJH of 400mg/kg group showed decreased serum level of corticosterone. Stress group showed significantly increase in serum level of ACTH, SJH of 400mg/kg group showed decreased serum level of ACTH. Conclusion: These results suggest that Sam-Jeong-Hwan(SJH) is effective in the treatment of depression.

• Journal of Korean Public Health Nursing
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• v.14 no.1
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• pp.122-130
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• 2000

This study was designed to investigate the effects of an aquatic exercise program on the physical function and depression among the community elderly. The subjects were 41 cases of aged over 65 who went to elderly college in Hawsung-Kun, Kyeongkee province. Seventeen of them were assigned to control group, while twenty four subjects to the experimental group. The period of data collection was from June., 1999 to November., 1999. The aquatic exercise program was developed by the author with the assistance of rehabilitation medicine doctor and physical therapist in the public health center. The program was carried out once a week for 6 months in regular swimming pool. Data were analyzed with t-test, $X^2$ test, ANCOVA. paired t-test using SAS 6.12. Results were obtained as follows: 1. The increments in the range of motion of the shoulder and knee joints in experimental group after exercise was significantly greater than those in the control group. 2. The physical pain score decreases significantly after the exercise in the experimental group only. 3. The experimental group revealed lower level of depression after exercise than the level before the exercise, whereas control group showed no significant changes in this level. These findings may indicate that the aquatic exercise program is effective in increasing the range of motion of shoulder and knee joints and also effective in decreasing pain, the level of depression. Accordingly. the aquatic exercise program can be adopted as an health promotion program for community elderly.

• Journal of Korean Academy of Nursing
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• v.41 no.1
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• pp.47-60
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• 2011

Purpose: This study was conducted to develop an e-Learning program that assists nursing students' clinical Purpose: This study was conducted to develop and evaluate a web-based education program for secondary stroke prevention. Methods: A web-based secondary stroke prevention education program was developed using the system's life cycle methods and evaluated by comparing the effects of education among three groups, a web group, a booklet group and a control group. Results: Knowledge level of both patients and family, as well as some health behavior compliance in the web-based and booklet education groups were significantly higher than those of the control group. Family support in the web-based and booklet education groups was significantly higher than that of the control group after 12 weeks. The urine cotinine level in the web-based education group was significantly lower than that of the control group after 12 weeks. Medication adherence, blood pressure and perceived health status were not statistically different among the three groups at any time. Conclusion: Webbased and booklet education programs were equally effective regarding the level of knowledge of patients and their families, family support, health behavior compliance, and urine cotinine level. These results demonstrate the potential use of a webbased education program for secondary stroke prevention.

• Journal of Korean society of Dental Hygiene
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• v.17 no.3
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• pp.465-478
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• 2017

Objectives: The purpose of this study was to investigate the relationship between the level of subjective stress recognition and oral symptom experiences including toothache, gum diseases, and oral soft tissue diseases in the Korean adolescents. Methods: The subjects were 68,043 adolescents recruited using a web-based survey, National Korean Youth Risk Behavior in 2015 by the Korean Center for Disease Control. For statistical analysis, SPSS 21.0 for Windows was used. Descriptive analysis and a Chi-square test were conducted to determine the factors associated with general characteristics, health behaviors, oral health behaviors, and level of subjective stress recognition. Finally, to investigate the relationship between the level of subjective stress recognition and oral symptom experiences, logistic regression analysis was performed. Results: Toothache related subjective stress recognition level was significantly higher in the moderate group with the score of 1.59 (95% CI; 1.49-1.68), and was greater in the high group with 2.38 (95% CI; 2.24-2.53) compared to the low group. Gum disease related subjective stress recognition level was significantly higher in the moderate group with 1.41 (95% CI; 1.32-1.51), and was greater in the high group with 1.99 (95% CI; 1.86-2.13). Oral soft tissue disease related subjective stress recognition level was significantly higher in the moderate group with 1.59 (95% CI; 1.45-1.74), and was greater in the high group with 2.55 (95% CI; 2.33-2.79). Bad breath related subjective stress recognition level was significantly higher in the moderate group with 1.48 (95% CI; 1.39-1.57), and was greater in the high group with 2.10 (95% CI; 1.97-2.25). Conclusions: Higher subjective stress recognition level was found to affect the oral symptoms experienced. Therefore, the stress management plan should be prepared through the cause identification of the main stress in the adolescents. Practical and systematic education is needed for oral health management in the schools.

• Journal of Trauma and Injury
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• v.19 no.2
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• pp.113-120
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• 2006

Purpose: The aim of this study was to evaluate the clinical characteristics of classic heat stroke in Korea and to identify factors of prognosis for heat stroke by comparing a survival group with a non-survival group. Methods: We retrospectively analyzed 27 patients with heat stroke who visited the Emergency Department of Kyungpook National University Hospital from March 2001 to February 2005. First, we divided the patients into two groups, the classic heat stroke group and the exertional heat stroke group, and compared them. Second, we compared the survival group with the non-survival group. Age, sex, cause, place where patients were found, underlying diseases, cooling time, performance of endotracheal intubation, initial Glasgow Coma Scale, initial vital sign, and laboratory findings were reviewed. Results: Five of 27 patients in heat stroke died. The classic heat stroke group had 20 patients. They were old and had more patients in the bathroom than the exertional heat stroke group had. The non-survival group showed lower blood pressure, lower initial GCS score, and higher respiratory rate than the survival group. In laboratory findings, the non-survival group also showed lower$HCO_3-$ level, lower albumin level, lower glucose level, more prolonged PT, and higher CK-MB level than the survival group. Delay in recognition of heat stroke and cooling were poor prognostic factors in heat stroke. Conclusion: The classic heat stroke group had patients who were old and found in the bathroom. Early recognition and treatment of heat stroke is important to reduce mortality. Cooling time, initial GCS score, mean arterial pressure, resipratory rate, $HCO_3-$, PT, CK-MB, and albumin seem to be meaningful when forming a prognosis for heat stroke patients.

• The Journal of Korean Medicine
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• v.21 no.1
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• pp.20-28
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• 2000

The purpose of this research is to investigate the synergistic effect of herb medicines with hydrocortisone and the regulation effect on the immune system of Onbitang and Dangguijakyaksan at the supernatant of PHA-P stimulated PBMC in the patients with minimal change nephrotic syndrome(MCNS). From the measurement of the concentration rate of IL-4, sCD23 and IL-13, the experiment yielded the following results : The Onbitang group showed a greater tendency to suppress IL-4 and IL-13 levels in MCNS group with no statistical significance. It showed very strong suppression in soluble CD23 compared with control group in MCNS group. The Dangguijakyaksan group, though not statistically significant, was inclined to suppress IL-4 level in MCNS group. It shows stronger suppression in sCD23 and IL-13 levels than these of control group in MCNS group. As for the synergistic effect, the group of hydrocortisone with herb medicines(Onbitang or Danguijakyaksan) produced more suppressive effect to IL-13 level in MCNS group than that of hydrocortisone-only group. They also tended to suppress sCD23 and IL-4 levels, though no statistical significance can be given. As to the suppressive effect of 1L-13 level, the group of Onbitang with hydrocortisone showed an increase of 22.6%, while the group of Dangguijakyaksan with hydrocortisone showed 14.7%. So Onbitang is more effective than Dangguijakyaksan. From the above results, a combinative treatment(herb medicines with hydrocortisone) can be an alternative method to substitute for steroid therapy. It can be a more effective therapy than steroid-only therapy because it is expected to reduce side effects and it shows more special effect to suppress IL-13 level. Based on the present results, further investigation concerning the serum IgE elevation is needed.