• Structural Engineering and Mechanics
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• v.65 no.6
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• pp.741-750
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• 2018

The aim of this study was to investigate the mechanical responses of a high-speed railway shield tunnel subjected to impact by a derailed train, with emphasis on the protective effect of the secondary lining. To do so, the extended finite element method was used to develop two numerical models of a shield tunnel including joints and joint bolts, one with a cast-in-situ concrete secondary lining and one without such a lining. The dynamic responses of these models upon impact were analyzed, with particular focus on the distribution and propagation of cracks in the lining structures and the mechanical responses of the joint bolts. The numerical results showed that placing a secondary lining significantly constricted the development of cracking in the segmental lining upon the impact load caused by a derailed train, reduced the internal forces on the joint bolts, and enhanced the safety of the segmental lining structure. The outcomes of this study can provide a numerical reference for optimizing the design of shield tunnels under accidental impact loading conditions.

• Wind and Structures
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• v.26 no.1
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• pp.11-24
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• 2018

Full-scale measurements of wind action on the open roof structure of the WuXi grand theater, which is composed of eight large-span free-form leaf-shaped space trusses with the largest span of 76.79 m, were conducted during the passage of Typhoons HaiKui and SuLi. The wind pressure field data were continuously and simultaneously monitored using a wind pressure monitoring system installed on the roof structure during the typhoons. A detailed analysis of the field data was performed to investigate the characteristics of the fluctuating wind pressure on the open roof, such as the wind pressure spectrum, spatial correlation coefficients, peak wind pressures and non-Gaussian wind pressure characteristics, under typhoon conditions. Three classical methods were used to calculate the peak factors of the wind pressure on the open roof, and the suggested design method and peak factors were given. The non-Gaussianity of the wind pressure was discussed in terms of the third and fourth statistical moments of the measured wind pressure, and the corresponding indication of the non-Gaussianity on the open roof was proposed. The result shows that there were large pulses in the time-histories of the measured wind pressure on Roof A2 in the field. The spatial correlation of the wind pressures on roof A2 between the upper surface and lower surface is very weak. When the skewness is larger than 0.3 and the kurtosis is larger than 3.7, the wind pressure time series on roof A2 can be taken as a non-Gaussian distribution, and the other series can be taken as a Gaussian distribution.

• Geomechanics and Engineering
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• v.37 no.3
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• pp.293-306
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• 2024

Influenced by the alternating effects of dynamic and static pressure during the mining process of close range coal seams, the surrounding rock support of cross mining roadway is difficult and the deformation mechanism is complex, which has become an important problem affecting the safe and efficient production of coal mines. The paper takes the inclined longwall mining of the 10304 working face of Zhongheng coal mine as the engineering background, analyzes the key strata fracture mechanism of the large inclined right-angle trapezoidal mining field, explores the stress distribution characteristics and transmission law of the surrounding rock of the roadway affected by the mining of the inclined coal seam, and proposes a segmented and hierarchical support method for the cross mining roadway affected by the mining of the close range coal seam group. The research results indicate that based on the derived expressions for shear and tensile fracture of key strata, the ultimate pushing distance and ultimate suspended area of a right angle trapezoidal mining area can be calculated and obtained. Within the cross mining section, along the horizontal direction of the coal wall of the working face, the peak shear stress is located near the middle of the boundary. The cracks on the floor of the cross mining roadway gradually develop in an elliptical funnel shape from the shallow to the deep. The dual coupling support system composed of active anchor rod support and passive U-shaped steel shed support proposed in this article achieves effective control of the stability of cross mining roadways, which achieves effective control of floor by coupling active support and preventive passive support to improve the strength of the surrounding rock itself. The research results are of great significance for guiding the layout, support control, and safe mining of cross mining roadways, and to some extent, can further enrich and improve the relevant theories of roof movement and control.

• Journal of Distribution Science
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• v.9 no.3
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• pp.55-64
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• 2011

This study is important in its focus to find key clues in the marketing strategy, consumer behavior, and communication processes that define the infantile obesity market. The study, the first of its kind, surveyed a target audience, purchasing group, and housewives in their quest to determine purchasing decisions and effective branding strategy planning for the infantile obesity market. Another key component of the study was to focus on the key direct and/or indirect distribution channels for the subject market. Recently, obesity has emerged as a major social concern; some studies show that the onslaught of an adverse eating culture in Korea emanates from the prevalence of fast-food dining establishments. Obesity among children leads to adult obesity, especially if the young people's parents are overweight; notably, if either one or both of the parents are obese, the percentage of young people eventually being obese is approximately 80 to 85 percent. Because obesity is the cause of many major health concerns later in life, the struggle for a healthy life is considerably adversely affected by parents' consumer behavior. Infantile obesity, resulting in adult obesity, is also an important national economic and social issue. The sizable direct and indirect economic costs, as well as the tremendous social costs of obesity, cannot be overstated. Effective food branding and advertising centered on food preferences and dietary behaviors, especially to children, creates an effective marketing effort that, ultimately, leads to positive results. Thus, the purpose of this study is to demonstrate that the treatment of childhood obesity in Korea, through the activation of a brand and retail market, can effectively solve social and economic problems that result from infantile and childhood obesity. In this study, obesity markets and distribution channels in the purchase decision-making factors determining factor based on it effective inspection and branding strategies and brand marketing communications strategy proposed measures contribute to the obesity drug market and further enable the childhood obesity problem is intended to assist in solving.

• Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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• 2003.07a
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• pp.173-177
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• 2003

최근에 인터넷을 이용한 화상회의, 실시간 정보서비스, 협동작업, VOD 서비스등의 요구가 증가하면서 이런 서비스들을 효율적으로 처리할 수 있는 멀티캐스트 통신이 등장하였다. 멀티캐스트 통신에서는 데이터의 보호를 위하여 그룹 키를 사용하는데 수시로 회원의 가입과 탈퇴가 이루어지는 동적인 멀티캐스트 그룹에서 안전하고 효율적인 그룹 키의 전송이 중요한 문제로 등장하였다. 본 논문에서는 지금까지의 그룹 키 전송에 대한 연구들을 살펴보고 효율적이고 안전한 그룹 키 전송 방법을 제안함으로서 통신에 필요한 키들을 보관해야 하는 저장공간의 용량을 최소화하고 그룹키 전송시 일대일 통신방식인 유니캐스트방식을 이용하여 효율적이고 안전한 전송이 될 수 있도록 하였다.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.5
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• pp.721-733
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• 2019

Objective: The objectives of this study were to investigate the thermal gelation properties and molecular forces of actomyosin extracted from two classes of chicken breast meat qualities (normal and pale, soft and exudative [PSE]-like) during heating process to further improve the understanding of the variations of functional properties between normal and PSE-like chicken breast meat. Methods: Actomyosin was extracted from normal and PSE-like chicken breast meat and the gel strength, water-holding capacity (WHC), protein loss, particle size and distribution, dynamic rheology and protein thermal stability were determined, then turbidity, active sulfhydryl group contents, hydrophobicity and molecular forces during thermal-induced gelling formation were comparatively studied. Results: Sodium dodecyl sulphate-polyacrylamide gel electrophoresis showed that protein profiles of actomyosin extracted from normal and PSE-like meat were not significantly different (p>0.05). Compared with normal actomyosin, PSE-like actomyosin had lower gel strength, WHC, particle size, less protein content involved in thermal gelation forming (p<0.05), and reduced onset temperature ($T_o$), thermal transition temperature ($T_d$), storage modulus (G') and loss modulus (G"). The turbidity, reactive sulfhydryl group of PSE-like actomyosin were higher when heated from $40^{\circ}C$ to $60^{\circ}C$. Further heating to $80^{\circ}C$ had lower transition from reactive sulfhydryl group into a disulfide bond and surface hydrophobicity. Molecular forces showed that hydrophobic interaction was the main force for heat-induced gel formation while both ionic and hydrogen bonds were different significantly between normal and PSE-like actomyosin (p<0.05). Conclusion: These changes in chemical groups and inter-molecular bonds affected protein-protein interaction and protein-water interaction and contributed to the inferior thermal gelation properties of PSE-like meat.

• Wind and Structures
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• v.16 no.6
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• pp.579-601
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• 2013

Interference effects are of considerable concern for group hyperboloidal cooling towers, but evaluation methods and results are different from each other because of the insufficient understanding on the structure behavior. Therefore, the mechanical performance of hyperboloidal cooling tower shell under wind loads was illustrated according to some basic properties drawn from horizontal rings and cantilever beams. The hyperboloidal cooling tower shell can be regarded as the coupling of horizontal rings and meridian cantilever beams, and this perception is beneficial for understanding the mechanical performance under wind loads. Afterwards, the mean external latitude wind pressure distribution, CP(${\theta}$), was artificially adjusted to pursue the relationship between different CP(${\theta}$) and wind-induced responses. It was found that the maximum responses in hyperboloidal cooling tower shell are primarily dominated by the non-uniformity of CP(${\theta}$) but not the local pressure amplitude CP or overall resistance/drag coefficient CD. In all the internal forces, the maximum amplitude of meridian axial tension shows remarkable sensitivity to the variation of CP(${\theta}$) and it's also the controlling force in structure design, so it was selected as an indicator to evaluate the influence of CP(${\theta}$) on responses. Based on its sensitivity to different adjustment parameters of CP(${\theta}$), an comprehensive response influence factor, RIF, was deduced to assess the meridian axial tension for arbitrary CP(${\theta}$).

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1901-1906
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• 2012

Background: The discovery that microRNA (miRNA) regulates metastasis provide a principal molecular basis for tumor heterogeneity. A characteristic of solid tumors is their heterogenous distribution of blood vessels, with significant hypoxia occurring in regions (centers of tumor) of low blood flow. It is necessary to discover the mechanism of breast cancer metastasis in relation to the fact that there is a differential distribution of crucial microRNA in tumors from centers to edges. Methods: Breast tissues from 48 patients (32 patients with breast cancer) were classified into the high invasive and metastatic group (HIMG), low invasive and metastatic group (LIMG), and normal group. Samples were collected from both the centers and edges of all tumors. The first six specimens were detected by microRNA array, and the second ten specimens were detected by real-time qRT-PCR and Western blot analyses. Correlation analysis was performed between the miRNAs and target proteins. Results: The relative content of miR-20a and miR-20b was lower in the center of the tumor than at the edge in the LIMG, lower at the edge of the tumor than in the center in the HIMG, and lower in breast cancer tissues than in normal tissues. VEGF-A and HIF-1alpha mRNA levels were higher in the HIMG than in the LIMG, and levels were higher in both groups than in the normal group; there was no difference in mRNA levels between the edge and center of the tumor. VEGF-A and HIF-1alpha protein levels were higher in the HIMG than in the LIMG, and protein levels in both groups were higher than in the normal group; there was a significant difference in protein expression between the edge and center of the tumor. Correlation analysis showed that the key miRNAs (miR-20a and miR-20b) negatively correlated with the target proteins (VEGF-A and HIF-1alpha). Conclusions: Our data suggest that miR-20a and miR-20b are differentially distributed in breast cancer, while VEGF-A and HIF-1alpha mRNA had coincident distributions, and VEGF-A and HIF-1alpha proteins had uneven and opposing distributions to the miRNAs. It appears that one of the most important facets underlying metastatic heterogeneity is the differential distribution of miR-20a and miR-20b and their regulation of target proteins.

• Geomechanics and Engineering
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• v.29 no.1
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• pp.91-97
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• 2022

The cohesive non-swelling soil (CNS) cushion technology has been widely applied in the subgrade and slope improvement at expansive soil regions. However, the mechanism of the inhibition effect of the CNS layer on expansive soil (ES) has not been fully understood. We performed four outdoor model tests to further understand the inhibition effect, including different kinds of upper layer and thickness, under the unidirectional seepage condition. The swelling deformation, soil pressure, and electrical resistivity were constantly monitored during the saturation process. It is found that when a CNS layer covered the ES layer, the swelling deformation and electrical resistivity of the ES layer decreased significantly, especially the upper part. The inhibition effect of the CNS layer increases with the increase of CNS thickness. The distribution of vertical and lateral soil pressure also changed with the covering of a CNS layer. The electrical resistivity can be an effective index to describe the swelling deformation of ES layer and analyze the inhibition effect of the CNS layer. Overall, the CNS deadweight and the ion migration are the major factors that inhibit the swelling deformation of expansive soil.

• Structural Engineering and Mechanics
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• v.53 no.3
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• pp.481-495
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• 2015

Many hydropower stations in southwest China are located in regions of brittle rock mass with high geo-stresses. Under these conditions deep fractured zones often occur in the sidewalls of the underground caverns of a power station. The theory and methods of fracture and damage mechanics are therefore adopted to study the phenomena. First a flexibility matrix is developed to describe initial geometric imperfections of a jointed rock mass. This model takes into account the area and orientation of the fractured surfaces of multiple joint sets, as well as spacing and density of joints. Using the assumption of the equivalent strain principle, a damage constitutive model is established based on the brittle fracture criterion. In addition the theory of fracture mechanics is applied to analyze the occurrence of secondary cracks during a cavern excavation. The failure criterion, for rock bridge coalescence and the damage evolution equation, has been derived and a new sub-program integrated into the FLAC-3D software. The model has then been applied to the stability analysis of an underground cavern group of a hydropower station in Sichuan province, China. The results of this method are compared with those obtained by using a conventional elasto-plastic model and splitting depth calculated by the splitting failure criterion proposed in a previous study. The results are also compared with the depth of the relaxation and fracture zone in the surrounding rock measured by field monitoring. The distribution of the splitting zone obtained both by the proposed model and by the field monitoring measurements are consistent to the validity of the theory developed herein.