• 재활간호학회지
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• 제1권1호
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• pp.83-92
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• 1998

This study was designed to determine the outcomes of the team-based cardiac rehabilitation programs for patients with Ischemic Heart Disease(IHD) on their level of health behavior performance, anxiety, and quality of life. A total of 19 in-patients with IHD who have had PTCA treatment at G.Hospital in Inchon were selected as subject to data collection from 1 May 1998 to 30 Oct. 1998. The experimental group, consisting of 11 patients participated in the Hospital's cardiac rehabilitation program was compared with the non-rehabilitation control group of 8 patients. The experimental group has been trained on the cardiac rehabliltation programfor 120-150minute during hospitalization by a team consisted of four specialists, those are cardiologist, head nurse, dietian, and the author. Also individual follow-up training and interview were performed for the members of experimental group at their every visit to the Hospital after discharge. For all subjects, scores on health behavior performance, anxiety, and quality of life were collected two days and 12 weeks after PTCA treatment by questionnaire. The collected data were analyzed with the SPSS. The results of this study were summarized as follows : 1) The experimental group shows significant increase in health behavior performance score compared to the control group(-2.27, p=.022). 2) There was no significant difference between two group's anxiety scores (-.24, p= .803) and quality of life scores(-1.86, p= .061). 3) The correlation between health behavior performance and anxiety ( .07, p= .771), and that between health behavior performance and quality of life( .12, p= .621) respectively were not significant statistically. But the correlation between anxiety and quality of life were significant reversely ( .49, p= .032).

• Archives of Pharmacal Research
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• 제19권4호
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• pp.286-291
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• 1996

Phenolic compounds are prevalent as toxins or environmental pollutants, but they are also widely used as drugs for various purpose including anticancer agent. A novel biphenolic compound, bis(2-hydroxy-3-tert-butyl-5-methylphenyl)methane (GERI-BPO02-A) was isolated from the fermentation broth of Aspergillus fumigatus F93 previously, and it has revealed cytotoxicity against human solid tumor cells. Its effective doses that cause 50% inhibition of cell growth in vitro against non-small cell lung cancer cell A549, ovarian cancer cell SK-OV-3, skin cancer cell SK-MEL-2 and central nerve system cancer cell XF498 were 8.24, 10.60, 8.83, $9.85\mug/ml$ respectively. GERI-BPO02-A has also revealed cytotoxicity against P-glycoproteinexpressed human colon cancer cell HCT15 and its multidrug-resistant subline HCT15/CL02, and its cytotoxicity was not affected by P-glycoprotein. We have also tested cytotoxicities of structurally related compounds of GERI-BPO02-A such as diphenylmethane, 1,1-bis(3,4dimethylphenyl)ethane, 2,2-diphenylpropane, 2-benzylpyridine, 3-benzylpyridine, $4,4^I-di-tert-butylphenyl$, bibenzyl, $2,2^I-dimethylbibenzyl$, cis-stilbene, trans-stilbene, 3-tert-butyl-4-hydroxy-5-methylphenyisulfide, sulfadiazine and sulfisomidine for studying of structure and activity relationship, and from these data we could suppose that hydroxyl group of GERI-BPO02A conducted important role in its cytotoxicity.

• Toxicological Research
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• 제23권2호
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• pp.159-164
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• 2007

Toxicity screening of a newly developed oral heparin derivative were carried out in 6 male cynomolgus monkeys (Macaca fascicularis), composed of a treatment group and vehicle control group. A newly orally active heparin derivative, developed by Seoul National University, was once given to treatment group at dose of 500 mg/kg. A treatment group did not show any change in body weights, hematological parameters including platelet-related varivables (platelet, PDW, PCT, MPV) and serum biochemical parameters (e.g., AST, ALT, BUN, etc.) for 2 weeks compared with those of vehicle control group. We also confirmed the maximum plasma concentration (Cmax, 1.73 IU/ml) and the time (Tmax, 1 hr) to reach Cmax. The present study will be valuable in the proper interpretation for nonclinical study using cynomolgus monkeys in the development of new drug of heparin derivative.

• 수산해양기술연구
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• 제42권3호
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• pp.148-157
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• 2006

A model experiment, simulation test using personal computer and real sea trial fishing were carried out to investigate the basic efficiency of bottom trawl net which can be used in the sea mount of North West Pacific, and experimental values were analyzed as the values of full-scale bottom trawl net. Hydrodynamic resistance for the full-scale trawl net according to the Koyama equation was 2.1 times higher than that of simulation and 2.4 times higher than that of model experiment at the average towing velocity. At the 3.5kt's of towing speed, net width of the full-scale trawl net was 2.5% smaller than that of simulation and 8.2% larger than that of model experiment. On the fishing experiment of the full-scale trawl net for the 3.5kt's of average towing speed, average net height of A group(same direction with external force) was 423.5% higher than that of model experiment and 457.1% higher than that of simulation and that of B group(opposite direction with external force) were 283.8% and 306.3% higher than in case of model experiment and Simulation respectively. Net mouth of the full-scale trawl net was 338.1-504.6% higher than those of model experiment and simulation in A group, and 525.2-745.3% higher in B group.

• Journal of Nutrition and Health
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• 제52권6호
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• pp.593-603
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• 2019

Purpose: Previous studies have highlighted that the nutritional behaviors among South Korean workers are far from ideal. This study examined the organizational influences affecting the eating practices of office workers in South Korea. Methods: We conducted in-depth interviews with 22 office workers at 12 companies in South Korea. The interviewer inquired about the employees' daily routines on food and beverage intake. The various factors that influence their food choices in their work environments were also explored. The interviews were transcribed and then analyzed using a content analysis. Results: A framework analysis revealed 7 key recurring themes, and these were grouped under three levels: team-, company-, and corporate group-levels. First, team dinners are core social events for all the workers and they tend to include high-caloric food and alcoholic beverages. The frequency of team meals and the food associated with them depend on various team characteristics such as gender composition, the nature of a team's work and the team leaders' emphasis on group meals. Second, the company's policies and practices regarding budget allocation for team meals and subsidies for cafeteria meals affect the workers' food intake practices. In addition, the physical environment of the worksite cafeterias can influence the choices of foods. Third, various corporate group policies that were not designed to target food intake had additional positive effects on the workers' eating behaviors. Conclusion: This study provides important insights into the broader organizational influences on the food consumption of employees in their workplace. These insights can be used to design and implement more effective intervention strategies for improving the nutritional behaviors of office workers.

• 한국전문물리치료학회지
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• 제17권3호
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• pp.11-19
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• 2010

The purpose of the study was to determine the effects of balance training with 'TETRAX' system, a balance training and assessment tool, on balance and mobility in acute hemiplegic patients. Nineteen matched subjects were assigned randomly into either an experimental group or a control group. An experimental group with 10 subjects received balance training with 'TETRAX' exercise program and conventional physical therapy interventions 5 times per week during 4 weeks. A control group with 9 subjects received conventional physical therapy interventions 5 times per week during 4 weeks. Outcome measures were taken before and after 4 weeks of interventions using the Stroke Rehabilitation Assessment of Movement (STREAM), the Berg Balance Scale (BBS), gait speed, and the fall down index. Results indicated that both exercise groups improved significantly in STREAM, BBS, and gait speed (p<.05). The experimental group had a little improvement than the control group. Both exercise groups did not show statistical significance in fall down index (p<.05). Following 4 weeks of intervention, except gait speed there was no statistically significant difference between two groups. However, these findings suggest that conventional physical therapy interventions with visual feedback training could be effective on improving balance and mobility than conventional physical therapy alone in acute hemiplegic patients.

• 한국식품위생안전성학회지
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• 제38권6호
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• pp.476-482
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• 2023

본 연구는 가열하여 섭취하는 냉동식품 중 빵류 20건 및 서류가공품 30건과 식품접객업소의 조리식품 중 감자튀김 20건을 대상으로 가열조리에 따른 아크릴아마이드 함량을 분석하였다. 에어프라이어를 이용한 냉동식품의 조리 전·후 아크릴아마이드 함량과 식품접객업소 조리식품의 아크릴아마이드 함량을 LC-MS/MS를 이용하여 분석하고 비교하였다. 아크릴아마이드 함량은 에어프라이어 조리 후 빵류 4건에서 0.167-0.401 mg/kg, 서류가공품 24건에서 0.071-0.694 mg/kg으로 나타났으며, 식품접객업소 조리식품은 모든 제품에서 0.118-0.977 mg/kg으로 나타났다. 이 중 국내 아크릴아마이드 권장규격인 1 mg/kg을 초과한 제품은 없었다. 하지만 유럽연합의 benchmark level (0.5 mg/kg)을 초과한 냉동 제품 3건을 튀김기 조리법으로 가열 조리하였을 때, 서류가공품 1건이 국내 권장규격을 초과하여 1.83 mg/kg으로 검출되었다. 아크릴아마이드에 대한 국내 노출량이 증가하는 추세이므로 아크릴아마이드 저감화를 위해 지속적인 평가와 관리가 필요한 것으로 판단된다.

• 건축역사연구
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• 제7권3호
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• pp.137-149
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• 1998

The purpose of this study is to learn from a lesson of the historical fact, the Team 10's break away from the CIAM, which is selected as the most important event in the whole 20th century architecture by author as a historian. The CIAM, organized in 1928 by leading European architects in order to propose new architecture in the industrial era, expanded to the world, met almost annually with an idea of economic efficiency, new functional order, and industrial production for thirty years. Young architects had conflicted with old established group from 6th congress, and after 10th congress they met independently in 1959; the CIAM was disappeared and the Team 10 was born. Main issue of the break-away was human aspect. The Team 10 started from real man, concept of 'human contact', 'sense of community', and 'belonging' instead of abstract functional order. Although CIAM did not suggest inhumane architecture, their biological criteria with sunlight, air, sufficient site became physical determinism. Critique against the Team 10, unsuccess for making humane architecture leads to underestimation like a generational hegemony struggle. However, architect is not specialist of life but form. Historical reevaluation for Team 10 should be that they are the first group to raise an human issue in architecture. Success or not to solve the problem belongs to another domain. After 1960, modern architecture was attacked from the common people, not clients but 'users'. Academic circle tried to solve the problem with behavioral approach through a clear process, 'design method' and with phenomenological approach on real human experience. However practice became reactionary tendency, to make form a little complex, they became post-modern and deconstruction form. Failure of the Team 10's form proved that a complex form does not necessarily make a good life of people. In the Korean historic situation of colony ruling, confusion of liberation, and the War, we did not know the existence of both CIAM and Team 10. After 1970s' economic development, we have just copied Western form from Modern via Post-Modern to Deconstruction. If we make architecture people mattered, we should start from the basic, learning from the Team's break-away, instead of copying.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.309-312
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• 2005

The need for LBS (Loc,ation Based Services) is increasing due to the wnespread of mobile computing devices and positioning technologies~ In LBS, there are many applications that need to manage moving objects (e.g. taxies, persons). The moving object join operation is to make pairs with spatio-temporal attribute for two sets in the moving object database system. It is import and complicated operation. And processing time increases by geometric progression with numbers of moving objects. Therefore efficient methods of spatio-temporal join is essential to moving object database system. In this paper, we apply spatial join methods to moving objects join. We propose two kind of join methods with TB- Tree that preserves trajectories of moving objects. One is depth first traversal spatio-temporaljoin and another is breadth-first traversal spatio-temporal join. We show results of performance test with sample data sets which are created by moving object ,generator tool.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.317-320
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• 2005

The LBS (Location-Based Services) are valuable information services combined the location of moving object with various contents such as map, POI (point of Interest), route and so on. The must general service of LBS is route determination service and its applicable parts are FMS (Fleet Management System), travel advisory system and mobile navigation system. The core function of route determination service is determination of optimal route from source to destination in various environments. The MODB (Moving Object Database) system, core part of LBS composition systems, is able to manage current or past location information of moving object and massive trajectory information stored in MODB is value-added data in CRM, ERP and data mining part. Also this past trajectory information can be helpful to determine optimal route. In this paper, we suggest methods to determine optimal route by querying past trajectory information in MODB system and verify the effectiveness of suggested method.