• Journal of Ginseng Research
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• v.40 no.4
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• pp.445-452
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• 2016

Background: Red ginseng and ginsenosides have shown plethoric effects against various ailments. However, little is known regarding the effect of red ginseng on morphine-induced dependence and tolerance. We therefore investigated the effect of red ginseng extract (RGE) and biotransformed ginsenosides Rh2, Rg3, and compound K on morphine-induced dependence in mice and rats. Methods: While mice were pretreated with RGE and then morphine was injected intraperitoneally, rats were infused with ginsenosides and morphine intracranially for 7 days. Naloxone-induced morphine withdrawal syndrome was estimated and conditioned place preference test was performed for physical and psychological dependence, respectively. Western blotting was used to measure protein expressions. Results: Whereas RGE inhibited the number of naloxone-precipitated jumps and reduced conditioned place preference score, it restored the level of glutathione in mice. Likewise, ginsenosides Rh2, Rg3, and compound K attenuated morphine-dependent behavioral patterns such as teeth chattering, grooming, wet-dog shake, and escape behavior in rats. Moreover, activated N-methyl-D-aspartate acid receptor subunit 1 and extracellular signal-regulated kinase in the frontal cortex of rats, and cultured cortical neurons from mice were downregulated by ginsenosides Rh2, Rg3, and compound K despite their differential effects. Conclusion: RGE and biotransformed ginsenosides could be considered as potential therapeutic agents against morphine-induced dependence.

• Journal of Korean Academy of Nursing
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• v.38 no.3
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• pp.474-482
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• 2008

Purpose: The purposes of this study were; 1) to test the validity and reliability of the Korean version of Rantz's Observable Indicators of Nursing Home Care Quality Instrument (ONHQ) and 2) to evaluate the quality of Korean nursing homes. Methods: The study employed a three-phase methodological research design. 1) The original instrument of Rantz's. ONHQ was translated into Korean and modified by Korean nursing home experts. 2) A pilot study using the modified instrument was done in 20 nursing homes to examine inter-rater reliability. 3) The validity and reliability were tested.in 98 nursing homes. Results: Seven factors were extracted through factor analysis: 'communication', 'care delivery', 'grooming', 'odor, 'environment-basics', 'environment-access', and 'environment-homelike'. These factors explained 86.07% of the total variance. Cronbach's alpha coefficient of the 30 items was .97 indicating a high internal consistency of the instrument. Inter-rater reliability according to Kappa was .82. The average score of nursing home quality was 112.07 indicating an average range of quality level. Conclusion: The Korean version of the ONHQ was identified as a tool with a high degree of validity and reliability. This tool can be effectively used to assess the quality of nursing homes by professions as well as family members.

• YAKHAK HOEJI
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• v.40 no.5
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• pp.545-549
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• 1996

Male Sprague-Dawley rats were exposed to the toluene at 3,000${\pm}$200ppm via inhalation for two hours in the single inhalation group and three weeks by two hours per day, six da ys per week in the repeated inhalation group. The blood toluene concentration in the repeated inhalation group was significantly lower than that in the single inhalation group after 210 and 240 minutes of exposure. The peak concentration of blood toluene was 58.13${\pm}$4.63${\mu}$g/ml in the single inhalation group and 54.24${\pm}$6.87mcg/ml in the repeated at the end of 120 minutes of the exposure. The behavioral change of rats for the initial 30 minutes of the toluene inhalation showed mildly increased movement and excitement but remained calm and inhibitory behaviors after that period; more inhibitory behaviors in the single inhalation group compared with the repeated inhalation group. In open-field test, after the termination of the toluene inhalation, no difference had been statistically observed between the toluene inhalation group and the control group in ambulation, rearing, preening and grooming.

• The Research Journal of the Costume Culture
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• v.6 no.3
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• pp.11-20
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• 1998

The purpose of this study was to investigate the clothing folk beliefs of Korea and to trace thought on rightness and wrongness implied in them. Data were collected from 1980's and selections were mae from them for the analysis of this research. Results and findings of this study can be summarized as follows: Clothing folk beliefs related to thought on rightness and wrongness appeared in various ranges and ways. They included clothing behaviors, attitudes, clothing habits, grooming, as well as clothing related activities such as sewing, laundary, ironing and pressing activities so on. They also included time, place, and occasions. It was found that behaviors, attitude, and habits against social norms and cultural values on social orders were regarded as not right., Those behaviors, attitudes, and habits were discouraged with clothing folk beliefs. Clothing folk beliefs were used as a means of educating and disciplining tool using or appealing human psychology. Also it was found that Korean clothing folk beliefs were functioned as means of transmitting social norms and cultural values from generation to generation. Thus, clothing folk beliefs can be regarded as one of the important cultural elements of Korea as well as means of socialization tool that contains so man information about Koreans.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.01a
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• pp.353-354
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• 2021

본 연구에서는 빠르게 발전하는 남성 화장품 시장 트렌드에 맞춰서 남성 고객과 남성 화장품을 타겟으로 하는 기업에 유용한 정보를 제공할 수 있는 데이터베이스 시스템을 구축하고자 한다. 아직까지는 여성에 비해 남성 고객과 남성 화장품에 대한 데이터 분석 및 연구가 현저히 적은 편이다. 본 연구는 남성 고객의 데이터와 빅데이터 자료를 바탕으로 구매율이 높은 상위 10개 제품명과 브랜드명, 소비자가 원하는 가격대의 유명하고 인기있는 제품, 특정 피부고민을 가진 고객이 구매한 제품 중 알레르기 유발 물질이 포함된 제품의 정보와 같은 유용한 정보들을 데이터베이스 시스템을 활용하여 산출해냈다. 이를 통해, 남성 화장품 시장이 앞으로 나아갈 방향에 대해 파악하고 국내 남성 화장품 시장의 발전에도 이바지할 수 있을 것으로 예측된다.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.7 no.3
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• pp.429-440
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• 2000

The purpose of this study was to validate self care outcomes included Nursing Outcomes Classification(NOC) developed by Johnson and Maas at the University of Iowa. A sample of 103 nurse experts working in university affiliated hospitals participated in this study. They were asked to rate indicators that examplified the outcomes on a scale of 1(indicator is not at all characteristic) to 5(indicator is very characteristic). A questionnaire with an adaptation of Fehring's methodology was used to establish the content validity of outcomes. The results were as follows : 1. All indicators were considered to be 'supporting' and no indicators were considered to be 'nonsupporting'. 2. 'Self care: Toileting' attained an OCV score of 0.884 and was the highest OCV score among self care outcomes. 3. 'Self care: Oral Hygiene' attained an OCV score of 0.756 and was the lowest OCV score among self care outcomes. 4. 'Self-care: Activities of Daily Living (ADL)' attained an OCV score of 0.845 and the highest indicator was 'eating'. 5. 'Self-care: Bathing' attained an OCV score of 0.810 and the highest indicator was 'washes body'. 6. 'Self-care: Dressing' attained an OCV score of 0.831 and the highest indicator was 'buttons clothing'. 7. 'Self-care: Eating' attained an OCV score of 0.815 and the highest indicator was 'chews food'. 8. 'Self-care: Grooming' attained an OCV score of 0.833 and the highest indicator was 'combs or brushes hair'. 9. 'Self-care: Hygiene' attained an OCV score of 0.823 and the highest indicator was 'washes hands'. 10. 'Self-care: Insrumental Activities of Daily Living(IADL)' attained an OCV score of 0.776 and the highest indicator was 'uses telephones'. 11. 'Self-care: Non-Parenteral Medication' attained an OCV score of 0.796 and the highest indicator was 'identifies medication'. 12. 'Self-care: Parenteral Medication attained an OCV score of 0.810 and the highest indicator were 'identifies medication' and 'administers medication correctly'. More outcomes need to be validated and outcomes sensitive to Korean culture need to be developed.

• Biomolecules & Therapeutics
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• v.12 no.4
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• pp.242-249
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• 2004

The main aim of this study was to investigate stress related activities of Sun-ginseng extract as a candidate for anti-stress-related functional supplement by comparing its effect to those of red ginseng, which is also known to alleviate stress. Normal group was not exposed to stress while the control group was exposed to stress. Rats were orally administered once a day with 200 mg red ginseng (RG) extract, 100 or 200 mg Sun-ginseng (SG) extract/kg body weight. Mice were given water containing 400 mg red ginseng extract, 200 or 400 mg SG/100 mL potable water. Rats were given supplements for 5 days without stress, and 5 days with restraint and electroshock stress. After final stress, stress-related behavioral changes of experimental animals were recorded and levels of blood corticosterone were measured. Mice were given supplements for 5 days through drinking water, and then fatigue related motor activity were recorded. SG-supplementation partially blocked stress effect on locomotion and elevated plus maze test in rats, and also partially blocked stress-induced behavioral changes such as freezing, burrowing, smelling, facewashing, grooming and rearing behavior in rats. SG-supplementation decreased blood corticosterone level which is increased by stress in rats. Effects of SG may not be modulated by GABAnergic nervous system. SG-supplementation prolonged swimming time and staying time on the wire and rotarod wheel in mice. These results suggest that SG partially protects living organisms from stress attack in some cases and thus has the potential to be used as a functional food to alleviate stress response.

• Biomolecules & Therapeutics
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• v.5 no.2
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• pp.133-149
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• 1997

4-week repeated dose toxicity of DA-5018, a new capsaicin analogue analgesic agent, was examined in 5D rats at dosage levels of 0,0.4,2, 10 and 50 mg/kg/day. DA-5018 was administered orally to 17 males and 17 females per group at doses of 0, 10 and 50 mg/kg and to 12 males and 12 females per group at doses of 0.4 and 2 mg/kg. After the administration period, 5 males and 5 females at the 0, 10 and 50 mg/kg were placed on withdrawal for 2 weeks. Treatment-related clinical signs were observed at 10 and 50 mg/kg. Clinical signs observed immediately after the administration of DA-5018 were grooming, sedation or depression, lacrimation, atacia, reddening of extremities and ears, ventral or lateral recumvincy, respiratory distress, cyanosis and convulsion. Delayed-type clinical signs including focal scabbing and depilation around nose were also observed 1 or 2 weeks after the start of administration of DA-5018. Only at the 50 mg/kg group, corneal opacities, reduced body weight gain (male) and death (male 6/17, female 3/17) were noted. In blood biochemical analysis, serum levels of glucose and triglyceride decreased at 10 and 50 mg/kg. In hematological examination, there were increases in the number of red blood cell, hemoglobin content and percent of hematocrit at 10 and 50 mg/kg. Pulmonary enlargement and hemorrhagic spot, focal scabbing and depilation around nose and corneal opacities were seen at the necropsy of the animals died during the dosing of DA-5018 50 mg/kg. Focal scabbing and depilation around nose were observed in the animals terminally necropsied at doses of 10 and 50 mg/kg. Histopathological examination revealed pulmonary hemorrhage, focal necrosis in the scabbed area, corneal necrosis, fibrosis and neovasculization in the stroma. At 0.4 and 2 mg/kg, there were no significant toxic changes attributable to the administration of DA-5018. In conclusion, target organs following to 4-week repeated dose of DA-5018 in the rat were determined to be lung, skin and eyes. Definite toxic dose and no-observed-adverse-effect-level (NOAEL) were estimated to be 50 and 2 mg/kg/day, respectively.

• Journal of the Korea Fashion and Costume Design Association
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• v.9 no.2
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• pp.69-83
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• 2007

The purpose of this study was to investigate the differences in the hairdo involvement and hairdo attitude influenced by clothing involvement. In addition, actual conditions of hairdo were investigated. The questionnaires were given to female residents in Seoul and Gyeong-gi province during September to October 2006. Four hundred and six questionnaires were used for data analysis. The collected data were analyzed by using SPSS 12.0 software with various techniques such as factor analysis, Cronbach's alpha, cluster analysis, ANOVA test, Duncan test, frequency analysis and $X^2-test$. The results of this study were as follows; 1. The factors for clothing involvement were found to be interests and pleasure in clothes, coordination of clothes, symbolic representation, fashionableness, and risk awareness. The hairdo involvement factors were found to be interests and pleasure in hairdo, fashionableness, symbolic representation, risk awareness, and coordination of hairdo. The factors for attitude toward hairdo were found to be orientations toward leader's fashion conformity, distinct individuality, constancy, and consciousness of others. 2. According to the level of clothing involvement, three types of group were defined. When difference in the hairdo involvement was analyzed, all factors showed significant differences. When difference in the hairdo attitude was analyzed, significant differences were found in orientations toward leader's fashion conformity, distinct individuality and consciousness of others. 3. Reason for choosing hair style is 'it's because they wanted the hair style', 'it's easy to groom', 'it's what they usually choose'. Average hair grooming time is less than 5 minute had higher rate, and then less than 10 minute came second. The money spend on buying consumption goods for hair treatment per month had the highest rate on spending 10,000 to 20,000won and the source of information on hairdo had the highest rate on hairdresser. The reason for choosing hair saloon had the highest rate on hairdressing skill, which shows that people choose hair saloons which they can trust on hair saloon's hairdressing skill.

• Journal of Fashion Business
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• v.19 no.1
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• pp.95-105
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• 2015

This study investigated the color culture in the Japanese Medieval Age. The Japanese Medieval Age included the Kamakura period (1180-1333) and Muromachi period (1336-1573), and the leading group transitioned from the Kuge families to the Buke families. The taboos about colors from ancient times became nominal, and forbidden colors, such as purple, celadon, and red, became the colors of the samurai, leading to beautiful soldier gears that were unparalleled in history. In the Kamakura period, colors that conveyed a strong impression were created and preferred with the combination of a samurai's reasonable spirit and zen thoughts. The period was also called "the era of hari", and cross dyeing based on basic colors such as suou (red), ai (blue), and kuchinasi (yellow) was popular. In both the Kamakura and Muromachi periods, conspicuous and strong colors were sought for costumes, and embroidery was used with gold leaf, silver leaf, gold threads, silver threads, and background color. The colors of costume preferred by Buke men in the period included green, blue, and brown. In the characteristics of the kosode, the sugan and hitadare were used for men's formal dress, while kosode was used for the grooming of the working class. In these periods, additionally, the working class began to be socially engaged in actively wearing the one-layer kosode, which became popular, and the characteristics of the Japanese Medieval Age, during which functionality and practicality was valued, were also reflected in the dressing.