• 제목/요약/키워드: grinding time

검색결과 371건 처리시간 0.031초

난용성 의약품의 생체이용률 증진을 위한 무정형 초미립자의 조제 : UDCA와 SLS의 혼합분쇄 효과 (Amorphous Ultrafine Particle Preparation for Improvement of Bioabailability of Insolube Drugs: Effect of Co-Grinding of UDCA with SLS)

  • 정한영;곽성신;김현일;최우식
    • 약학회지
    • /
    • 제46권2호
    • /
    • pp.102-107
    • /
    • 2002
  • The particle size of medicinal materials is an important physical property which affects the pharmaceutical behaviors such as dissolution, chemical stability, compressibility and bioavailability of solid dosage forms. The size reduction of raw pharmaceutical powder is needed to formulize insoluble drugs or slightly soluble drugs and to improve the pharmaceutical properties such as the solubility, the pharmaceutical mixing and the dispersion. The objective of the present study is to evaluate the grinding characteristics of ursodeoxycholic acid(UDCA) as a model of insoluble drugs. The effects of the grinding time and the amount of additive on particle size distribution of ground UDCA were investigated. Grinding of insoluble drug, UDCA and a series of dry co-grinding experiments of UDCA with sodium lauryl sulfate(SLS) as an additive were carried out using a planetary ball mill. It was measured that the median diameter and the particle size distribution of ground products with grinding UDCA and additive SLS by Mastersizer. As a result of co-grinding of UDCA and SLS, the particle size of co-grinding products was decreased more than single grinding one. However, it was observed that co-grinding products were reaggregated to larger particles after 120 min.

A comparative study of grinding mill type on aluminium powders with carbon nano tube: traditional ball mill and planetary ball mill

  • 최희규;최경필;배대형;이승백;이웅;김성수
    • 한국재료학회:학술대회논문집
    • /
    • 한국재료학회 2009년도 추계학술발표대회
    • /
    • pp.27.2-27.2
    • /
    • 2009
  • Grinding characteristics for aluminium and carbon nanotubes (CNTs) powder during traditional and planetary ball milling investigated from the viewpoint of particle behaviour with the aimat developing CNT-dispersed samples ground based on powder metallurgy routes.In this work, a comparison between the pure aluminium and CNT input aluminium grinding was carried out to determine grinding time effect on size reduction.We observed that the use of the curly small-diameter multi-walled carbon nanotubes (MWCNTs) attributed to the beneficial role of the MWCNTs as grinding aids. It is suggested that careful choices of the sizes of CNTs and Al powders would allow fine-grinding of composite particles with uniformly distributed CNT reinforcements thereby ensuring improved properties of the final composites produced by low-temperature compacting.

  • PDF

연삭숫돌 주축 및 공작물 회전체 진동을 고려한 원통 연삭 가공의 동특성 해석 (Dynamic Analysis of External Cylindrical Grinding Considering Spindle and Workpiece Vibrations)

  • 최상현;김덕현;안유민
    • 한국정밀공학회지
    • /
    • 제17권6호
    • /
    • pp.192-198
    • /
    • 2000
  • This paper presents multi degree analysis of self-exited vibration of grinding system including spindle and workpiece rotational effect. The governing equations are derived by applying the finite element method to structure of spindle and workpiece rotor and by estimating the grinding force. Vibration analysis is carried out for external cylindrical plunge grinding. Displacement of workpiece and grinding force is simulated with machining time. Using this model, effects of characteristics of spindle bearing and major grinding conditions on chatter growth rate are predicted. Some of results are compared with those of other previous model and show good agreements.

  • PDF

고능률 고속연삭에서 열원 모델에 관한 연구 (A Study on Heat Source Model to High Efficiency Speed Grinding)

  • 김남경
    • 한국공작기계학회논문집
    • /
    • 제10권3호
    • /
    • pp.1-6
    • /
    • 2001
  • An analytical thermal model of HESG(higt efficiency speed grinding) is presented, in which the heat flux to workpiece in grinding zone is modeled as time dependent and moves along a slope decided by contact chord(approximation of con-tact arc). By matching the maximum surface temperature of workpiece derived from this model to the maximum surface temperature of grinding wheel composite as done in Lavins simple thermal model, the relation of maximum surface tem-perature and energy partition of workpiece to grinding speed is obtained. In high speed grinding, as wheel speed increases, energy partition decreases with no regard to table speed.

  • PDF

흑연의 구상화기구를 이용한 주철본드 다이어몬드 숫돌의 개발 (Development of Cast Iron Bonded Grinding Wheel by Using Spheroidization Mechanism of Graphite)

  • 유기태;정해도;전형일
    • 한국정밀공학회:학술대회논문집
    • /
    • 한국정밀공학회 1995년도 추계학술대회 논문집
    • /
    • pp.61-64
    • /
    • 1995
  • Grinding has been adapted as a finishing process,which can carry out form and surface integrity at the same time. Recently, high efficient and precise grinding technique is required bacause the needs for functional parts such as silicon wafer,ceramic,and electric materials are increasing. Accordingly, the development of grinding wheel appropriate to that purpose is very important. So, in this paper we newly developed a diamond grinding wheel by applying the superior characteristics of spheroidal graphite of the cast iron sintered product. Especially, a electric resistance sintering method was applied in which rapid heat treatment is possible. Finally, we have achieved successful results that the grinding wheel has high hardness,durability and grinding ability,and satisfies above conditions.

  • PDF

다구찌 실험 계획법을 이용한 광통신용 지르코니아($ZrO_2$)페룰의 연삭조건 최적화 실험 (Optimal Grinding Condition of $ZrO_2$, Ferrule for Optical Fiber Connector Using the Taguchi Method)

  • 김종형;서창민;채정식
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2004년도 춘계학술대회
    • /
    • pp.993-998
    • /
    • 2004
  • In this paper, the effects of grinding conditions on the surface roughness of $ZrO_2$ ferrule applying to the optical fiber connector were investigated. The mesh number of grindstone, the grinding speed and the time schedule during grinding were regarded as main cutting parameters that have an effect on the surface roughness. And then, optimal combinations for chamfering grinding were obtained by using the Taguchi method. In addition, analytic values for maximum surface roughness ($R_{max}$) estimated by the theoretical equations which were derived from the formative model of surface roughness on the chamfering grinding were compared with those of the experiments.

  • PDF

Kaolinite-Aluminum Trihydroxide의 혼합물의 혼합분쇄효과 및 Mullite의 생성에 미치는 영향 (Mixed Grinding Effect on Kaolinite-Aluminum Trihydroxide Mixture and Its Influence on Mullite Formation)

  • 류호진
    • 한국세라믹학회지
    • /
    • 제34권2호
    • /
    • pp.195-201
    • /
    • 1997
  • 본 논문은 kaolinite(Al2O3.2SiO2.2H2O)-aluminum trihydroxide(Al(OH3) 혼합물을 소결전에 planetary ball mill을 사용하여 건식 중에서 혼합분쇄한 후, 이 혼합물을 사용하여 소결하는 동안에 mullite의 생성거동을 연구한 것이다. 혼합물의 입자크기 감소는 분쇄 초기에 현저하였으며, 분쇄기간이 증가함에 따라 미립자들이 응집하는 현상을 보였다. 혼합물의 결정구조는 planetary ball milling에 의한 혼합분쇄에 따라 쉽게 비정질화되었으며, 비정질화되는 정도는 분쇄시간이 증가함에 따라 증가하였다. Kaolinite의 초기 분순물로 존재했던 anatase를 제외한 mullite상만이 상대적으로 낮은 소결온도인 1523K에서 혼합분쇄한 혼합물의 소결체에서 나타났다. 한편, 분쇄하지 않은 혼합물의 소결체의 경우는 이 온도에서 mullite 상 이외에 corundum, cristobalite, Al-Si spinel상이 공존하는 형태로 나타났다. 따라서, 혼합분쇄처리는 출발원료의 미소 규모에 있어서 균일혼합 및 분산을 촉진시키며, 또한 결정구조변화에 따른 열분해온도의 변화일으켜, 상대적으로 낮은 온도에서 고순도의 mullite를 직접 생성하는데 효과적이였다.

  • PDF

연삭 공정의 연속 진단을 위한 모니터링에 관한 연구 (A Study on the Monitoring Technology for the Continuous Detection of Grinding Process)

  • 강재훈
    • 한국생산제조학회지
    • /
    • 제8권1호
    • /
    • pp.74-80
    • /
    • 1999
  • Recently, manufacturing work has been transformed to small scale production form with various types to act up to user's expectation from mass production with a little items required in the past. Then FMS using NC type machinaries has been applied actively also in domestic manufacturing line to meet thus tendency, but there are many machining troubles occured during work process not be settled yet. Nowdays high efficiently has been required no less than high precision in grinding work for the improvement of productivity. In this study, to represent more advance FMS can be adapted to thus situation In-process type monitoring method using AE and Current sensors is suggested to investigate the machining condition in grinding process. As results form this experimental study, it is recognized well that grinding conditions and dressing point of in time cab be estimated effectively using monitoring method suggested. Furthermore, surface shape of grinding wheel on voluntary point of in time can be predicted indirectly through the observation and comparison of AE signal waveform obtained as performance of continuous dressing work.

  • PDF

평면연삭 공정에서의 표면 거칠기 기상계측 (On-the-machine measurement of surface roughness in a surface grinding process)

  • 김현수
    • 한국정밀공학회:학술대회논문집
    • /
    • 한국정밀공학회 1996년도 춘계학술대회 논문집
    • /
    • pp.232-236
    • /
    • 1996
  • This paper deals with an on-the-machine measurement method for roughness of ground surface by using flux ratio of scattered lights. A sensor and control unit is developed so as to e applied to surface grinding processes. The performance of the sensor is compared with that of stylus. The experimental investigation shows that not onlythe sensor has good performance as a surface roughness sensor but alsothe sensor is very useful for monitoring grinding condition in order to detect ill-conditioned grinding or dressing time.

  • PDF