• Applied Chemistry for Engineering
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• v.28 no.4
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• pp.397-403
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• 2017

The number of patients suffering from Alzheimer's disease is increasing year after year and almost approaching 15% of the total elderly population. Although it is critical to detect the early stage of Alzheimer's disease, which is a serious illness causing cognitive deficits, various existing diagnosis methods such as MRI, PET and CSF analysis could be the burdens for patients due to their high costs and long time to diagnosis. In order to tackle some of challenging issues for such existing diagnosis methods, extensive efforts have been made on developing fast and convenient biochip sensing methodologies for the diagnosis of Alzheimer's disease with a droplet of patient biofluids (e.g., blood). In this mini-review, we highlight some of the latest biochip sensing technologies that could qualitatively and quantitatively analyze blood biomarkers used for Alzheimer's disease diagnostics and discuss briefly related research trends and future aspects.

• Journal of Biosystems Engineering
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• v.40 no.4
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• pp.373-393
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• 2015

Background: Cellulose is a ubiquitous, renewable and environmentally friendly biopolymer, which has high promise to fulfil the rising demand for sustainable and biocompatible materials. Particularly, the recent progress in the synthesis of highly crystalline cellulose-based nanoscale biomaterials, namely cellulose nanocrystals (CNCs), draws significant attention from many research communities, ranging from bioresource engineering, to materials science and engineering, to biological and biomedical engineering to bionanotechnology. The feasibility of harnessing CNCs' unique biophysicochemical properties has inspired their basic and applied research, offering much promise for new biomaterials with diverse advanced functionalities. Purpose: This review focuses on vital issues and topics on the recent advances in CNC-based biomaterials with potential, in particular, for bionanotechnology and biological and biomedical engineering. The challenges and limitations of CNC technology are discussed as well as potential strategies to overcome them, providing an essential source of information in the exploration of possible and futuristic applications of the CNC-based functional "green" nanomaterials. Conclusion: CNCs offer exciting possibilities for advanced "green" nanomaterials, driving innovative research and development in a wide range of fields, including biological and biomedical engineering.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.23 no.5
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• pp.559-565
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• 2010

In this study we propose noise energy harvesting for green infrastructure development. In this regard, infrastructures such as railroad, subway, and road are taken into consideration as sources of noise which provides energy through certain wave forms. As the need of recycling noise energy became reasonable due to the increase of infrastructure usage, the capacity and property of our noise energy generating device, which uses electromagnetic induction for electricity generation, are analysed in this paper. Consequently, the outcomes of this experiment show the fact that maximum electricity is generated from the device at a specific point of noise frequency, and the relation between air pressure caused by noise and the electricity generated by the device is in a specific proportional form either linear or non-linear. The major points of developing noise energy generating device in order to apply it into social infrastructure are discussed in this paper as well.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.4 no.3
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• pp.279-283
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• 2003

This study was carried out to establish the manufacturing formulation of tea-bag type garlic tea. In order to eliminate of garlic-specific odor and taste, the masking effect of various additives against garlic flavor was determined with sensory evaluation. Leaves of green tea, arrowroot and Solomon's seal were screened as highly effective auxiliary ingredients in garlic tea. When two materials among the selected three auxiliary materials were mixed the same percentage, overall flavor of garlic tea synergistically was enhanced. The optimum concentration of garlic powder and stevioside as a sweetener were 20∼30％ and 1％, respectively. Therefore, three types formulation of garlic tea was establish. When the color, turbidity and total solid concentration of three formulated garlic teas were compared with those of commercially available formulated green tea containing unpolished rice, the latter was more yellowish color and the former was more superior to turbidity and total solid concentration.

• Journal of Mushroom
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• v.12 no.4
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• pp.258-262
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• 2014

We aim to elucidate suitable mixed color of light during development of fruit body in Pleurotus ostreatus. The four mixed color of LED(Light Emitting Diode), blue and white, green and white, blue and green and green and red LED, were irradiated for formation of fruit-body. First, as effect of mixed color of LED, the properties of fruit body of P. ostreatus in blue and white LED irradiation were showed higher commercial yields than those in control(fluorescent lamp). And the ergothioneine was the highest at the blue and white LED. Second, we could obtain higher commercial yields than those at the $1{\mu}mol/m^2/s$ of light intensity by blue and white LED in P. ostreatus.

• Journal of Plant Biotechnology
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• v.7 no.2
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• pp.97-103
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• 2005

This study was carried out to obtain basic information for gene manipulation in potent edible tobacco (Nicotiana tabacum cv. TI 516). N. tabacum cv. TI 516 is a plant for a possible candidate to use as an edible vaccine, since it contains a low level of nicotine. The effective plant regeneration system through leaf disc culture was achieved using a MS basal medium supplemented with 0.1 mg $1^{-1}$ NAA and 0.5 mg $1^{-1}$ BA. In order to transform the N. tabacum cv. TI 516 with the green fluorescent protein (GFP) gene, Agrobacterium tumefaciens LBA 4404 containing the GFP gene was used. Genomic PCR confirmed the integration of the GFP gene into nuclear genome of transgenic plants. Expression of the GFP gene was identified in callus, apical meristem and root tissue of transgenic N. tabacum cv. TI 516 plants using fluorescence microscopy. Western blot analysis revealed the expression of GFP protein in the transgenic edible tobacco plants. The amount of GFP protein detected in the transgenic tobacco plants was approximately 0.16% of the total soluble plant protein (TSP), which was determined by ELISA.

• Journal of Biosystems Engineering
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• v.34 no.6
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• pp.411-419
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• 2009

This study was carried out to develop a shredding-burying machine for application of gramineae green manure crops that were tall and had high biomass yield such as sudan grass and rye. We made a prototype to operate both shredding and burying concurrently to attach at middle-sized tractors. Field tests were performed with the prototype to treat rye and sudan grass. The test results showed that the average cutting length became shorter and the quantity of entwined stem became obviously decreased when the PTO shaft speed was fast and running speed was slow. Also, We found, when the cut stem length became shorter, the burying ratio became more increasing and the PTO power requirement became more decreasing. Working efficiency of the prototype was better than conventional Rotary. The test results for treating rye/sudan grass with prototype showed that average cutting length was 21.2/22.5 cm and burying ratio was 98.4/98.1% when the PTO shaft speed was 1,000/1,000 rpm and running speed was 0.25/0.17 m/s. Also, the working performance of the prototype was 0.79 and 1.14 h/10 a for rye and sudan grass, respectively. Finally, we found that the prototype of shredding-burying machine was better for labor than conventional method that required at least 3 times bigger tractor.

• Nutrition Research and Practice
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• v.7 no.5
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• pp.366-372
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• 2013

The application of polyphenols has attracted great interest in the field of functional foods and nutraceuticals due to their potential health benefits in humans. However, the effectiveness of polyphenols depends on their bioactivity and bioavailability. In the present study, the bioactive component from green tea extract (GTE) was administrated orally (50 mg/kg body weight/day) as free or in a microencapsulated form with maltodextrin in rats fed a high fructose diet. High fructose diet induced features of metabolic syndrome including hypertriglyceridemia, hyperuricemia, increased serum total cholesterol, and retroperitoneal obesity. In addition, myocardial fibrosis was increased. In rats receiving high fructose diet, the lowering of blood triglycerides, total cholesterol, non esterified fatty acid (NEFA) and uric acid, as well as the reduction in final body weight and retroperitoneal fat weight associated with the administration of GTE, led to a reversal of the features of metabolic syndrome (P < 0.05). In particular, the administration of microencapsulated GTE decreased myocardial fibrosis and increased liver catalase activity consistent with a further alleviation of serum NEFA, and hyperuricemia compared to administration of GTE. Taken together, our results suggest that microencapsulation of the bioactive components of GTE might have a protective effect on cardiovasucular system by attenuating the adverse features of myocardial fibrosis, decreasing uric acid levels and increasing hepatic catalase activity effectively by protecting their bioactivities.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.2
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• pp.23-38
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• 2002

The purpose of this paper is to propose directions for urban greening and nature conservation in small-to-medium-sized cities in Korea for implementation of the Local Agenda 21 (LA 21 hereafter). In this paper, the status of implementation of the LA 21 in both Korea and Japan have been examined. In addition, the green-related plans of both countries have been compared. The cities of Jeonju and Sagamihara were chosen as examples to compare. The result of the research is as follows: 1)With regard to the responsible bodies, in Korea, the implementing plans were initiated by the environment-related authorities of local governments while, in Japan, the plans of action were initiated through consultative committees reflecting opinions from citizens and business entities. 2)Concerning the status of implementation of LA 21, the city of Jeonju has adopted a plan of action and then implemented the plan through a consultative body without adequate legal ground. On the other hand, the city of Sagamihara has enacted a local ordinance to implement the LA 21 It was learned that the newly enacted ordinance has positively been interrelated to existing environmental plans. 3)Regarding urban greening and nature conservation plans, the city of Jeonju has focused on comprehensive measures to preserve and restore ecology while the city of Sagamihara has clearly suggested educational purposes in its plans in addition to preserving and restoring ecology. 4)In terms of support by law or legal system concerned, it has been teamed that, compared with Japan, Korean plans have not been properly supported by law or the legal system to urban greening and nature conservation plans. The same was shown in the city of Jeonju as compared with the city of Sagamihara. As for future directions, the follow are proposed: 1) establishment of a local Committee on Sustainable Development, 2) enactment of relevant and regulations such as the Master Plan of Parks and Green Open paces, 3) establishment of ecological greening plans.

• KIEAE Journal
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• v.9 no.3
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• pp.61-68
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• 2009

Gwangju Metropolitan Government & Ministry of Environment have signed a model city in response to Climate Change agreement. The agreement calls for Gwangju to cut greenhouse gas emissions 10% below 2005 levels by 2015. Gwangju has seen this agreement as an opportunity to cut pollution and conserve the environment as well as to reinvigorate local economy. According to policy of Gwangju, Gwangju held design competition for Gwangju City Arboretum on march, 2009. The purpose of design competition was to give a wide publicity to Gwangju as Hub City of Asian Culture and construct carbon-neutral arboretum in accordance with the policy of 'Low-Carbon and Green Growth'. First of all, a design concept of arboretum is 'winding, round, overlay 'to reflect the landscape of Nam-do which is surrounded by mountains and river flows through the village. Second, the arboretum has five different places with these themes - Forest of Festivals, Health, Nature, Nostalgia, Education and Future. Each place has a symbolic theme park and different flow planning respectively. Third, the most critical point is that the arboretum is a carbon-neutral park. Gwangju arboretum will soon be developed in metropolitan sanitary landfill and constructed as the O2 arboretum based on low carbon strategy. Fourth, the O2 arboretum suggests specialized issue : 'Energy Saving', 'Recycling System', 'Green Network', 'Water System(rainwater maintenance and wetland development)'. Besides, main buildings(greenhouse, visitor center, Nam-do experience exhibition hall, and forest museum) is designed in consideration of harmony with topography character, surroundings. Also, planting will be a multilayer plant based on native landscape trees in consideration of function and the growth characteristics.