• Journal of Chest Surgery
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• 제49권6호
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• pp.427-434
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• 2016

Background: Recent studies have demonstrated the benefits of off-pump coronary bypass grafting over the on-pump technique in patients with chronic kidney disease (CKD). To further reduce the risk of acute kidney injury and the need for renal replacement therapy, even in patients undergoing off-pump coronary artery bypass grafting, we adopted protocol-based perioperative management for patients with CKD. Methods: From December 2012 to March 2015, 265 patients underwent isolated off-pump coronary artery bypass grafting. To analyze renal function in a stable condition, we excluded 12 dialysis-dependent end stage renal failure and 10 emergency or urgent cases. Among the remaining 243 patients, 208 patients had normal kidney function (normal group), and 35 patients had CKD (CKD group). Minimizing contrast exposure, ensuring adequate hydration, using strict drug dosage adjustment, and optimizing hemodynamic status were key elements of the protocol for the CKD group. Results: The risk of acute kidney injury was about ${\times}3$ higher in the CKD group than in the normal group (p=0.01). Estimated glomerular filtration rates and serum creatinine levels deteriorated until the third postoperative day in the CKD group. However, by adopting protocol-based perioperative management, this transient renal dysfunction recovered to preoperative levels by the fifth postoperative day without requiring renal replacement therapy in all cases. Conclusion: Off-pump coronary bypass surgery combined with this protocol-based perioperative management strategy in patients with non-dialysis-dependent CKD could mostly be performed without renal replacement therapy.

• 한국자원식물학회지
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• 제27권2호
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• pp.183-187
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• 2014

헛개나무(Hovenia dulcis var. koreana Nakai, Korea raisin tree)는 동아시아가 원산지이며, 식 약용 수종으로서 밀원수종으로도 가치가 증대되고 있는 수종이다. 본 연구는 헛개나무의 절접에 의한 접수의 채취시기와 연령 및 비닐하우스 설치에 따른 접목활착율의 효과를 조사하는데 목적이 있다. 헛개나무 신품종은 절접에 의한 접목 결과 클론간 유의적인 차이가 인정되지 않았다. 온대 북부 권역에서는 휴먼기인 춘분 전에 접수를 채취하는 것이 가장 적합하며, 비닐하우스를 설치하는 경우에는 86% 이상의 높은 접목 활착율을 얻을 수 있다. 접수 연령은 1년지가 가장 적합하며 접목 후 비닐터널을 설치하여 접목상을 관리하면 80% 이상의 높은 접목활착율을 얻을 수 있는 것으로 나타났다.

• 한국세라믹학회지
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• 제54권2호
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• pp.102-107
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• 2017

The dependence of the IR optical properties of PMMA/$Al_2O_3$ nanocomposite on the alumina content was investigated in the wavelength range of $3500-2800cm^{-1}$. The samples were prepared via emulsion polymerization technique using oleic acid as a coupling agent. Grafting density calculations were carried out by means of elemental analysis CHN to yield the best coupling agent content. FTIR analysis confirmed the existence of a chemical bond between aluminum oxide and oleic acid. The outcomes of XRD analyses showed the presence of cubic gamma aluminum oxide in the nanocomposite, in contrast to the amorphous nature of PMMA. TEM images showed the core-shell morphology of the particles other than pristine PMMA. Optical constants of the nanocomposite were calculated based on FTIR spectra and the Kramers-Kronig equations. The presence of nano alumina modified some of the optical indexes in IR region.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권4호
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• pp.322-330
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• 2007

Backgrounds: To overcome limited amount of autogenous mucosa for the reconstruction of various mucosal defect including oral mucosal defect, tissue engineered mucosa has been recently introduced. However, introduced conventional technique of tissue engineered mucosa still have serious pitfalls such as long fabrication time, fragility of the reconstructed mucosa, and complexity of the technique. Aim of the study: To examine whether the complex of preconfluent autologous keratinocytes and autologous PRP(Platelet rich plasma) can reconstruct oral mucosa on the muscular flap with easier and faster way compared to conventional mucosal tissue engineering technique. Materials and methods: One day before the operation, oral mucosa(3mm in diameter) were taken and treated for extraction of oral keratinocytes according to the routine manner. The day of operation, oral keratinocytes were prepared in the laboratory and then moved to the operating theater. Autologous PRP was also prepared and then mixed with oral keratinocytes just before grafting on the prepared muscular flap. After keratinocyte-PRP complex was seated, then a sterilized rubber sheet was placed on the graft and the elevated skin flap was replaced and sutured. Biopsies were proceeded at 3, 5, 7, 14 and 21 days. Tissue samples were evaluated clinically, histologically, and immunohistochemically. Results: All of the oral keratinocyte-PRP complexes were successfully grafted on the recipient sites(100%). On 3 days after the operation, 1-2 continuous epithelial layer and many inflammatory cells were observed. On 5 days after the operation, increase of layers of keratinocyte was observed with less inflammatory response. Thickness of the layers was gradually increased from 7 to 21 days after the operation. Cytokeratin confirms epithelium in every specimen. Conclusions: Preconfluent graft of autogenous oral keratinocytes mixed with autogenous PRP have successfully reconstructed myo-mucosal flap. This technique could be a useful alternative for oral mucosal reconstruction in the near future.

• 헤리티지:역사와 과학
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• 제47권1호
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• pp.164-179
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• 2014

해남 대흥사 대웅보전에는 석가모니불을 중심으로 좌우에 약사불과 아미타불을 배치한 형식의 석가삼세불상이 봉안되어 있다. 그동안 이 삼세불상은 목조불로 알려져 왔으나 X-선 촬영 결과, 본존불을 제외한 좌우불에서 나무 위에 입힌 소조층이 함께 관찰되었다. 따라서 대흥사의 삼세불상은 조선시대 목조불상 및 소조기법이 적용된 불상을 함께 살펴볼 수 있는 좋은 사례가 될 수 있을 것이다. 조선시대 접목조불상의 전형을 보여주고 있는 본존 석가모니불상은 크게 5개의 목재를 접목하여 형상을 완성하고 있으며, 약사와 아미타불은 10개 이상의 목재를 접목하여 외형에 가깝도록 조각한 뒤 그 위로 점토를 발라 소조기법으로 형상을 완성하고 있다. 즉 내부의 목재가 심(芯)의 역할을 한다고 할 수 있는데, 목재의 접목방식이 조선시대의 목조불상보다는 소조불상의 기법에 가깝다. 그러나 목심 위에 새끼줄을 감고 그 위에 점토를 두껍게 바른 것이 아니라 나무 위에 직접 점토를 얇게 발랐으며, 얼굴 부분이 완전히 목조로만 이루어진 것이 특징적이다. 이와 같은 이유로 애초 작가의 조성의도가 목불이었을 가능성도 배제할 수 없으나 복장기록에 '소성(塑成)'이라는 단어가 사용된 것으로 보아 불상 조성이 완료된 시점에 이들 불상을 소조상으로 인식했음을 알 수 있다. 즉 대흥사 좌우불은 조선시대식 소조기법의 한 예로 보아도 좋을 것이라 생각한다. 따라서 본 논문에서는 대흥사 삼세불상의 X-선 촬영을 통해 얻은 화상정보를 바탕으로 이들 불상의 내부구조와 접목방식을 살펴보고 이를 통해 조선시대 불상 제작기법을 밝혀보고자 하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제36권3호
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• pp.124-130
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• 2014

Onlay bone grafting, guided bone regeneration, and alveolar ridge split technique are considered reliable bone augmentation methods on the horizontally atrophic alveolar ridge. Among these techniques, alveolar ridge split procedures are technique-sensitive and difficult to perform in the posterior mandible. This case report describes successful implant placement with the use of piezoelectric hinge-assisted ridge split technique in an atrophic posterior mandible.

• Archives of Plastic Surgery
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• 제41권6호
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• pp.740-747
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• 2014

Background Autologous fat graft has become a useful technique for correction of acquired contour deformity in reconstructed breasts. However, there remains controversial regarding the efficacy and safety of the practice for reconstructive breast surgery. Methods A retrospective review was performed on 102 patients who had secondary fat grafting after breast reconstruction. Fat harvest, refinement and injection were done by Coleman's technique. All patients were followed up postoperatively within 1 month and after 6 months including physical examination and ultrasonography. In 38 patients, the reabsorption rate was calculated by serial changes of thickness between skin and pectoral fascia in the ultrasonic finding. Locoregional recurrence rate was compared with control group of 449 patients who had breast reconstruction without fat graft in the same time period. Results Average 49.3 mL fat was injected into each breast. The most common location of fat graft was upper pole, followed by axilla, lower and medial breasts. During 28.7 months of average follow-up period, 2.9% of total patients had symptoms of palpable mass on fat graft side and ultrasonography identified fat necrosis and cyst formation in 17.6% of the patients. Calculated fat reabsorption rate was 32.9%. Locoregional recurrence was occurred in 1 patient (0.9%) and the rate was not different significantly with control group (2%). Conclusions Although further studies are required to provide surgeons with definitive guidelines for the implementation of fat grafting, we propose autologous fat graft is an efficient and safe technique for secondary breast reconstruction.

• Journal of Chest Surgery
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• 제47권3호
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• pp.287-290
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• 2014

We report a modified technique for pulmonary endarterectomy (PEA) on a 67-year-old man with chronic thromboembolic pulmonary hypertension (CTEPH) who presented with dyspnea. He was referred to our medical center for coronary artery bypass grafting. CTEPH had not been detected in his first visit to another medical center, but upon re-evaluation, the diagnosis was confirmed. PEA was performed with a modified method, which seems to be safe and suitable for the removal of clot and fibrotic materials. Iatrogenic dissection was performed with normal saline injection in the pulmonary artery, and then, the clot was removed completely. Although the technique may not be applicable for all cases, it can be used as an alternative to using an aspirating dissector and a pair of forceps.

• Journal of Veterinary Science
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• 제24권3호
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• pp.31.1-31.6
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• 2023

Allograft arthroplasty is a promising cartilage-resurfacing technique. A 14-year-old horse was diagnosed with a medial femoral condyle subchondral bone cyst. Allografts were harvested from a young donor animal and implanted to fill the cyst cavity. A visual assessment of the surgical site was possible during follow-up arthroscopy. In addition to a desirable gliding surface and a good adaptation of the grafts, fibrillation of the cranial ligament of the medial meniscus was noted and debrided. The recipient horse became sound four months after follow-up surgery with a high level of owner satisfaction. In conclusion allograft transplantation is a promising technique for treating subchondral bone cysts.

• Journal of Periodontal and Implant Science
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• 제40권1호
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• pp.25-32
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• 2010

Purpose: The performance of implant surgery in the posterior maxilla often poses a challenge due to insufficient available bone. Sinus floor elevation was developed to increase the needed vertical height to overcome this problem. However, grafting materials used for the sinus lift technique eventually show resorption. The present study radiographically compared and evaluated the changes in height of the grafting materials after carrying out maxillary sinus elevation with a window opening procedure. This study also evaluated the difference between two xenogenic bone materials when being used for the sinus lifting procedure. Methods: Twenty-one patients were recruited for this study and underwent a sinus lift procedure. All sites were treated with either bovine bone (Bio-$Oss^{(R)}$) with platelet-rich plasma (PRP) or bovine bone (OCS-$B^{(R)}$)/PRP. A total of 69 implants were placed equally 6-8 months after the sinus lift. All sites were clinically and radiographically evaluated right after the implant surgery, 7-12 months, 13-24 months, and 25-48 months after their prosthetic loading. Results: Changes of implant length/bone length with time showed a statistically significant decreasing tendency (P<0.05). There was no significant change in the Bio-$Oss^{(R)}$ group (P>0.05). In contrast, the OCS-$B^{(R)}$ group showed a significant decrease with time (P<0.05). However, no significant difference was observed between the two groups (P>0.05). Conclusions: The results showed that there was significant reduction in comparison with data right after placement, after 7 to 12 months, 13 to 24 months, and over 25 months; however, reduction rates between each period have shown to be without significance. No significant difference in height change was observed between the Bio-$Oss^{(R)}$ and the OCS-$B^{(R)}$ groups.