• 한국수자원학회논문집
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• 제51권4호
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• pp.313-322
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• 2018

Step의 높이는 하상재료 입경의 크기와 거의 같은 상관관계가 있으며, 하도경사에 따라 증가하고, 하도 폭과 step 파장은 거의 같은 크기로서 하도경사가 증가하면 step 파장은 감소하는 것으로 분석되었다. 하도 폭과 step 폭은 뚜렷한 상관관계가 있으며, 하도 폭의 증가에 따라 step 폭도 증가하는 것으로 분석되었다. 또한, step 파장은 하도 폭에 의하여 규모가 정해지고, step 높이는 step을 형성하는 암석의 크기에 의해 지배되기 때문에 step-pool의 종단면의 하상구조는 하도경사에 따라 변화하는 것으로 판단된다. Pool의 규모는 하도 폭, 입경 및 하도경사와 상관성이 큰 것을 확인하였다. 따라서 하천의 step-pool 구조 특성은 다양한 인자들의 영향을 받지만 대표적으로 입경, 하도 폭 및 하도경사로서 설명할 수 있는 것으로 분석되었다.

• 지질공학
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• 제16권3호
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• pp.293-300
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• 2006

조수 간만의 차가 큰 서해 해안 매립지역에서의 지하수 유동을 지층별로 표준관입시험을 통한 N값의 산출, 현장투수 시험을 통한 투수계수 측정, 인공위성 영상자료에 대한 선구조 분석 및 각 시험시추공에서 조석의 변화에 따른 지하수 유향유속을 측정하여 비교 분석하였다. 현장투수시험을 통하여 얻은 투수계수는 풍화대 구간이 해성퇴적토충보다 작은 값들을 보이지만 전반적으로 분포 경향이 비슷하게 나타났다. 지하수 유향유속은 해성퇴적토층에서 조석의 변화 방향인 동-서 방향인 반면, 풍화대 구간에서는 특정 지점에서 선구조와 일치하는 N45E 방향이 우세하였다. 24시간 동안의 관측에서 지하수 유향변화는 전반적으로 조석의 변화보다 약 2시간 정도 늦게 나타났으며, 이는 조석 효과에 의한 수리경사가 계속적으로 변동되며 나타나는 압력파의 전달에 소요되는 시간으로 판단된다.

• Clinical and Experimental Reproductive Medicine
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• 제45권1호
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• pp.17-24
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• 2018

Objective: To investigate sperm chromatin/DNA integrity, global DNA methylation, and DNMT mRNA transcription in men with oligoasthenoteratozoospermia (OAT) compared with normozoospermic men. Methods: Semen samples from 32 OAT patients who comprised the case group and 32 normozoospermic men who comprised the control group were isolated and purified using a standard gradient isolation procedure according to World Health Organization criteria. DNMT1, DNMT3A, and DNMT3B transcripts were then compared between groups using real-time quantitative reverse-transcription polymerase chain reaction. Global DNA methylation in sperm was determined by an enzyme-linked immunosorbent assay. Protamine deficiency and the proportion of apoptotic spermatozoa were evaluated using chromomycin A3 (CMA3), aniline blue (AB), and toluidine blue (TB) staining, as well as the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. The p-values < 0.05 were considered to indicate statistical significance. Results: Significantly higher proportions of AB+, TB+, CMA3+, and TUNEL+ spermatozoa, as well as DNMT3A and DNMT3B transcription, were found in the OAT group. Positive correlations were detected between sperm parameters, DNA/chromatin damage, and DNMT3A and DNMT3B transcripts. Global DNA methylation was significantly higher in the OAT patients and had a significant correlation with abnormal results of all sperm chromatin integrity tests, but was not associated with DNMT1, DNMT3A, or DNMT3B expression. Conclusion: Oligoasthenoteratozoospermic men showed abnormal sperm parameters, abnormal chromatin/DNA integrity, and a higher global DNA methylation rate, as well as overexpression of DNMT mRNA.

• Steel and Composite Structures
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• 제19권6호
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• pp.1549-1560
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• 2015

This paper presents the characterization of fatigue crack in the A283 Grade C steel using the MMM method by identifying the effects of magnetic flux leakage towards the crack growth rate, da/dN, and crack length. The previous and current research on the relation between MMM parameters and fatigue crack effect is still unclear and requires specific analysis to validate that. This method is considered to be a passive magnetic method among other Non-Destructive Testing (NDT) methods. The tension-tension fatigue test was conducted with a testing frequency of 10 Hz with 4 kN loaded, meanwhile the MMM response signals were captured using a MMM instrument. A correlation between the crack growth rate and magnetic flux leakage produces a sigmoid shape curve with a constant values which present the gradient, m value is in the ranges of 1.4357 to 4.0506, and the y-intercept, log C in the ranges of $4{\times}10^{-7}$ to 0.0303. Moreover, a linear relation was obtained between the crack length and magnetic flux leakage which present the R-Squared values is at 0.830 to 0.978. Therefore, MMM method has their own capability to investigate and characterize the fatigue crack effects as a main source of fracture mechanism for ferrous-based materials.

• 약학회지
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• 제60권2호
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• pp.64-72
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• 2016

Jakyakgamcho-tang is a well-known traditional herbal medicine and has been used for the treatment of mainly pains in oriental medicine. In this study, analytical method for the quantitative determination of the eleven marker components, gallic acid (1), oxypaeoniflorin (2), paeoniflorin (3), albiflorin (4), liquiritin (5), isoliquiritin (6), ononin (7), liquiritigenin (8), benzoylpaeoniflorin (9), paeonol (10), and glycyrrhizin (11) in Jakyakgamcho-tang decoction was performed using an ultra-performance liquid chromatography-electrospray ionization-mass spectrometer. The analytical column for separation of the compounds 1~11 was used an UPLC BEH $C_{18}$ ($100{\times}2.1mm$, $1.7{\mu}m$) column and column oven temperature was maintained at $45^{\circ}C$. The mobile phase consisted of 0.1% (v/v) aqueous formic acid (A) and acetonitrile (B) by gradient elution. The flow rate was 0.3 ml/min and injection volume was $2.0{\mu}l$. Correlation coefficient in the calibration curves of the compounds 1~11 were showed a good linearity with more than 0.99. The limit of detection and limit of quantification values of the compounds 1~13 were detected in the ranges 0.06~18.43 ng/ml and 0.18~58.29 ng/ml, respectively. Among the compounds 1~11, the compounds 10 were not detected in this sample, while the ten compounds, 1~9 and 11, were detected $44.05{\sim}19,289.05{\mu}g/g$ in Jakyakgamcho-tang extract.

• 한국환경과학회지
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• 제26권7호
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• pp.803-815
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• 2017

In this study of the oak wilt disease that has occurred in a large scale in a protected area located near South Korea's metropolitan region, a detailed analysis has been conducted on the terrain, species and Diameters at Breast Height (DBH) of infected trees to identify the distribution of infection properties in the affected area. Taking into consideration the distribution of oak tree vegetation, a total of 4,640 quadrats in a size of 10 m by 10 m, have been set; and oak tree species, the DBH and infection damage per quadrat have been investigated. Geological properties have been analyzed according to elevation, slope, aspect and micro topography while a weighted value has been given according to the degree of infection in order to calculate an infection index. Through correlation analysis, the infection ratio of seriously-damaged and withered trees and the infection index have been analyzed with regards to the geological properties, tree species and DBH. The analysis shows that the disease tends to affect an area with medium elevation rather than those in the highest or lowest areas and that serious damage has been observed at rugged spots with a steep gradient (more than $30^{\circ}$). Although there has been no distinct tendency with regards to aspect, the infection ratio is relatively high in areas facing the north while the seriously-damaged and withered ratio are high in areas facing the south. In terms of micro topography, more damage has been spotted in valley terrain. Quercus mongolica has sustained more damage than other species. When it comes to the DBH, as seen in previous studies, large trees have suffered severe damage, but the analysis has also revealed conspicuous damage to medium trees with a DBH of 15-20 cm, which had not previously been considered at high risk.

• 한국환경생태학회지
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• 제3권1호
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• pp.28-41
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• 1989

가야산 국립공원과 홍류동 및 치인지구의 삼림군집을 대상으로 ordination 및 classification의 정량적 분석기법을 사용하여 식물군집구조를 밝히고 천이계열을 추정하기 위하여 40개의 조사구(1조사구당 500$m^2$)를 설치하였다. TWINSPAN에 의한 Classification분석에서 최종적으로 8개의 군집으로 분리되었고, 건조형군집은 소나무 및 잣나무가 우점종이었으며, 습윤형은 졸참나무, 신갈나무, 서어나무, 까치박달나무가 우점종이었다. 습윤형은 다시 표고에 의해 구분할 수 있었으며 낮은 표고에서의 군집은 졸참나무가, 높은 표고에서의 군집은 신갈나무가 우점종이었다. DCA에 의한 ordination결과는 제1축에서 소나무가 우점종인 군집과 졸참나무, 신갈나무, 서어나무, 까치박달나무가 우점종인 군집으로 분리되었고, TWINSPAN의 제1 division의 결과와 거의 일치하였다. DCA의 제1축과 토양수분, 토양산도, 표고, 최대종다양도, Shannon의 종다양도지수와는 고도의 부의 상관관계를 나타냈다. 유사도지수는 각군집간에 매우 낮은 값이었으며, 각 군집의 종다양성분석에서는 각 군집의 우점종에 따라 큰 차이가 있었다. 개체수와 종수와의 관계는 개체수가 증가할 수록 종수는 감소하였으며, 개체수가 증가할 수록 종다양성지수는 감소하였다.

• Investigative Magnetic Resonance Imaging
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• 제20권4호
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• pp.231-240
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• 2016

Purpose: To determine whether liver stiffness (LS) measured by magnetic resonance elastography (MRE) can predict the outcome of radiofrequency ablation (RFA) in hepatocellular carcinoma (HCC) patients. Materials and Methods: A total of 107 patients with Child-Pugh class A liver function who were treated with RFA for single HCC and who had undergone a gradient-echo MRE within 6 months before RFA were included. We evaluated the relationship between the LS values and the ablation volume, local tumor progression (LTP), and intrahepatic distant recurrence (IDR). We also constructed receiver operating characteristic (ROC) curves to examine the role of LS in predicting liver function deterioration, which was defined as an increase of Child-Pugh score by one point or more at 1 year after RFA. Results: There was no significant correlation between LS and ablation volume, and neither time to LTP nor IDR was associated with LS. Among the 66 patients who did not have recurrence 1 year after RFA, 5 patients (7.6%) developed liver function deterioration. A high LS value was significantly associated with development of liver function deterioration after RFA and the area under the ROC curve was 0.764 (95% CI 0.598-0.929, P = 0.003). Conclusion: LS measured by MRE could not predict ablation volume and tumor recurrence. However, high LS values were significantly associated with development of liver function deterioration.

• 한국자기학회지
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• 제19권3호
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• pp.81-84
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• 2009

상관효과 U가 전자구조와 자성에 미치는 영향을 검토하기 위하여 대표적 자성물질인 철의 덩어리, 단층 및 사슬 구조에 대해 연구하였다. 이를 위하여 U = 3 eV로 택하여, 총 퍼텐셜 보강 평면파동 에너지 띠 방법을 이용하여 LDA+U 및 GGA+U 근사 하에 전자구조 계산을 수행하였다. 비교를 위하여 LDA 및 GGA를 이용한 계산도 수행하였다. 그 결과 U의 효과를 포함시켰을 때 덩어리 철의 경우 자기모멘트가 $0.3{\mu}_B$ 증가하여 실험값이나 LDA 및 GGA 계산에 비해 과다하게 계산되는 것으로 나타났으나, 단층이나 사슬의 경우는 그렇게 큰 차이를 보이지 않았다. 이로부터 전자구조 계산 시대상 계에 따라 U의 효과를 적절히 고려하여야 함을 알았다.

• Natural Product Sciences
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• 제22권2호
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• pp.93-101
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• 2016

For efficient quality control of the Samryeongbaekchul-san decoction, a powerful and accurate an ultra-performance liquid chromatography (UPLC) coupled with electrospray ionization (ESI) tandem mass spectrometry (MS) method was developed for quantitative analysis of the thirteen constituents: allantoin (1), spinosin (2), liquiritin (3), ginsenoside Rg1 (4), liquiritigenin (5), platycodin D2 (6), platycodin D (7), ginsenoside Rb1 (8), glycyrrhizin (9), 6-gingerol (10), atractylenolide III (11), atractylenolide II (12), and atractylenolide I (13). Separation of the compounds 1 - 13 was performed on a UPLC BEH $C_{18}$ column ($2.1{\times}100mm$, $1.7{\mu}m$) at a column temperature of $40^{\circ}C$ with a gradient solvent system of 0.1% (v/v) formic acid aqueous-acetonitrile. The flow rate and injection volume were 0.3 mL/min and $2.0{\mu}L$. Calibration curves of all compounds were showed good linearity with values of the correlation coefficient ${\geq}0.9920$ within the test ranges. The values of limits of detection and quantification for all analytes were 0.04 - 4.53 ng/mL and 0.13 - 13.60 ng/mL. The result of an experiment, compounds 2, 6, 12, and 13 were not detected while compounds 1, 3 - 5, and 7 - 11 were detected with 1,570.42, 5,239.85, 299.35, 318.88, 562.27, 340.87, 12,253.69, 73.80, and $115.01{\mu}g/g$, respectively.