• Title/Summary/Keyword: gp53

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Application of Euclidean Distance Similarity for Smartphone-Based Moving Context Determination (스마트폰 기반의 이동상황 판별을 위한 유클리디안 거리유사도의 응용)

  • Jang, Young-Wan;Kim, Byeong Man;Jang, Sung Bong;Shin, Yoon Sik
    • Journal of Korea Society of Industrial Information Systems
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    • v.19 no.4
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    • pp.53-63
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    • 2014
  • Moving context determination is an important issue to be resolved in a mobile computing environment. This paper presents a method for recognizing and classifying a mobile user's moving context by Euclidean distance similarity. In the proposed method, basic data are gathered using Global Positioning System (GPS) and accelerometer sensors, and by using the data, the system decides which moving situation the user is in. The decided situation is one of the four categories: stop, walking, run, and moved by a car. In order to evaluate the effectiveness and feasibility of the proposed scheme, we have implemented applications using several variations of Euclidean distance similarity on the Android system, and measured the accuracies. Experimental results show that the proposed system achieves more than 90% accuracy.

Neuroprotective Effect of Lilii bulbus, Nelumbins semen on the Sleep Deprivation-induced Oxidative Stress in the Hippocampus Dentate Gyrus (수면박탈로 유도한 Hippocampus Dentate gyrus의 산화 스트레스에 대한 백합, 연자육의 신경세포보호효과)

  • Choi, Mi Hye;Park, In Sik
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.1
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    • pp.65-74
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    • 2017
  • Sleep deprivation is an extremely common event in today's society. It has caused learning cognitive skill deterioration and poor concentration, increased disease such as heart disease, diabetes and obesity, sexual function decrease, infertility increase, depression and autonomic nervous system disorder. Sleep deprivation-induced stress caused NADPH oxidase and oxidative stress. And this oxidative stress induces apoptosis. Lilii bulbus and Nelumbins semen are known to mental and physical relaxation effects. In this study, we induced sleep deprivation(SD) in Sprague-Dawley rats in water for 5 days and thereafter administered orally L. bulbus and N. semen for 5 days. Brain tissues were observed by histochemical, immunohistochemical and tunel staining. The immunoreactives of Tumor necrosis factor ${\alpha}$, Neuronal nitric oxide synthases, Phospho-SAPK/JNK and gp91-phox of the L. bulbus administered group and N. semen administered group were weaker than those of sleep deprivation group. In the L. bulbus administered group and N. semen administered group, apoptosis was decreased than that of sleep deprivation group. Proapoptotic p53, Bax, Cleaved caspase 3 immunoreactives of the administered group were weaker than those of sleep deprivation group, whereas anti-apoptotic Bcl-2 immunoreactity was stronger in the L. bulbus administered group and N. semen administered group. Antioxidant mechanism such as DJ-1, superoxide dismutase 1, Nuclear factor-like 2 immunoreactives of the L. bulbus and N. semen administered group were stronger than those of sleep deprivation group. These results demonstrate that L. bulbus, N. semen had the neuroprotective effects on the sleep deprivation-induced oxidative stress in the hippocampus.

Grid-based Cloaking Area Creation Scheme supporting Continuous Query Processing for Location-based Services of Peer-to-Peer Environment (P2P 환경의 위치 기반 서비스에서 연속적인 질의 처리를 지원하는 그리드 기반 Cloaking 영역 설정 기법)

  • Kim, Hyeong-Il;Lee, Ah-Reum;Chang, Jae-Woo
    • Spatial Information Research
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    • v.18 no.3
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    • pp.53-62
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    • 2010
  • Recent development in wireless communication technology, like GPS, and mobile equipments, like PDA and cellular phone, make location-based services (LBSs) popular. However, because, users continuously request a query to a server in the LBSs by using their exact locations, privacy information could be in danger. Therefore, a mechanism for users' privacy protection is required for the safe and comfortable use of LBSs by mobile users. For this, we, in this paper, propose a grid-based cloaking area creation scheme supporting continuous LBSs in peer-to-peer environment. The proposed scheme creates a cloaking area by using Chord protocol, so as to support the continuous LBSs in peer-to-peer environment. Finally, we show from a performance analysis that our cloaking scheme outperforms the existing cloaking schemes, in terms of service time.

Microsomal Mixed Function Oxidase and Lipid Peroxidation in Liver and Lung of Sterptozotocin-Induced Diabetic Rats (Streptozotocin 유발 당뇨쥐의 간장 및 폐조직에서의 Microsomal Mixed Function Oxidase System과 과산화지질 생성)

  • 이순재;김관유
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.1
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    • pp.21-26
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    • 1996
  • 본 연구는 streptozotocin 유발 당뇨쥐에서의 MFO계활성 변화 및 이에 지질과산화를 관찰하고자 체중이 140kg 내외의 Sprague-Dawley 종 흰쥐 숫컷을 대조군과 당뇨 유발 시험군으로 나누어 4주간 사육하였다. 당뇨군은 STZ로 당뇨를 유발시켰으며 당뇨 유발 6일후 쥐를 희생기켜 간조직 및 폐조직 microsome 중의 cytochrome $P_{450}$ 및 cytochrome $b_[5}$ 함량과 NADPH-cytochrome $P_{450}$ reductase 활성도를 측정하고 아울러 microsome내의 지질과산화물을 측정하여 다음과 같은 결과를 얻었다. 실험군간에 식이 섭취량은 차이가 없었으나, 체중 증가량과 식이 효율은 당뇨군이 STZ군에 비해 현저하게 감소하였다. 간장 및 폐조직의 무게는 대조군과 당뇨군간에 유의적인 차이는 없었다. 간조직 및 GP조직 중의 cytochrome $P_{450}$ 함량은 대조군에 비해 당뇨군이 150%, 175%씩 증가하였다. 간조직 및 폐조직 중의 cytochrome $b_{5}$은 대조군에 비해 당뇨군이 53%,116%씩 각각 증가하였다. 간조직에서의 NADPH-cytochrome $P_{450}$ reductase 활성은 당뇨군이 대조군에 비해 46% 증가하였으며, 폐조직에서는 75%증가하였다. 지질과산화물가는 당뇨군이 대조군에 비해 간족에서는 약 95% 높았으며 폐조직에서는 73%높았다. 이상의 결과에서 STZ 유발 당뇨쥐에서는 MFO system의 활성도가 대조군에 비해 현저하게 증가되고 지질과산화반응이 같으 srudgid이 촉진되었으며 폐조직에서도 간조직에서와 비슷한 경향이었다. 이러한 것은 당뇨군에서는 MFO system의 활성증가로 free radical 생성이 증가되고 그 결과 지질과산화가 촉진되었다고 볼 수 있다.

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Development on Management System of Structure's Displacement Using GPS (GPS를 이용한 구조물 변위 관리 시스템 개발)

  • Roh, Tae-Ho;Lee, Jong-Chool
    • Journal of Korean Society for Geospatial Information Science
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    • v.11 no.2 s.25
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    • pp.53-59
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    • 2003
  • Many facilities have been constructed due to the rapid development of science and economy, and the tendency for larger sizes and higher stories in constructing are being accelerated due to the development of technologies, and the efficient use of limited spaces. The safety problems of constructions are being frequently brought up. So, a technique by which the monitoring of the safety of constructions can be easily done must be developed as soon as possible. In this research an management system for structure's displacement using satellite survey was studied. The results of having established the management system for structure's displacement as a GPS positioning system were that data acquisition was easier than that from using normal survey equipment, and data from the satellite survey can be applied to the database of management system. The data of the GPS suey were rather large values to determine the safety of single stories, but can probably be used in establishing the management system using the structure's displacement.

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A Study on Coordinate Determination of Territorial Sea Base Point by GPS Surveying (GPS에 의한 영해기점의 위치결정)

  • Choi, Yun-Soo;Park, Byung-Uk;Hwang, Byung-Ho;Cho, Moon-Hyoung
    • Journal of Korean Society for Geospatial Information Science
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    • v.10 no.3 s.21
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    • pp.53-59
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    • 2002
  • Territorial sea baseline is a borderline, with the effectuation of the United Nations Convention on the Law of the Sea of 1982, for the related sea zone negotiations with neighboring countries. Its position must be determined to international standard like WGS84 coordinate system. In this study, GPS survey for territorial sea points was performed to determine territorial baseline around five islands in the yellow sea, and the results of them were compared with previous coordinates. Territorial sea point, outermost spot of a nation's realm, tend to be placed in end up low-tide elevations or precipice. Therefore traditional surveying methods are hard to take accurate observations, so that GPS survey is most effective. Through the study, the scientific and reasonable methods for GPS surveying procedure is presented. The results of coordinate comparison show that there are wide difference between the old and new coordinates, and it is necessary for the whole area of islands to calculate displacements by GPS surveying.

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Research Trends of Oriental Medicine in Korea and Meta-analysis of Articles related to Stroke in the Journal of Korean Oriental Medicine (한의학회지의 뇌졸중 관련논문을 통한 한의학 연구동향과 질적 메타분석)

  • Ko, Seong-Gyu
    • The Journal of Internal Korean Medicine
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    • v.22 no.2
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    • pp.223-237
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    • 2001
  • Objective : There have not been studies on the oriental medicine research trends and qualitative analysis of Korean oriental medicine articles in Korea, particularly in the oriental medicine area. This study's purpose is to appreciate Korean oriental medicine's research trends and assess the quality of the Korean oriental medical journals' level. This study will help upgrade Korean oriental medical journals. Method : We found 93 stroke-related articles in the Journal of Korean Oriental Medicine, published between 1980(Volume 1) and 2001(Volume 45). We surveyed the institutes involved in each study, and the number of people in each study. We seperated by epidemiological study design, the studies into categories. Campbell and Stanley's study design into 6 categories, statistical methods into 13 categories. Next, we assessed the 41 articles by a checklist, which had 10 categories. The quality score was analyzed by survey variables over the period, which were divided by the date of publication: the 1980s, the first half of the 1990s, second half of the 1990s and 2000s. Results : 46.3% od the studies didn't use statistical methods. 56.1%, were case series studies by classification of epidemiological study design, and 53.6% were one-shot case studies designed by Campbell and Stanley's study design. The quality score was 58.33 point 60 is average. In quality level by Browman GP etc.'s, 83.0% of the studies were included in V levels. But, the quality scores were significant by presence of reviewer system, statistical method's usage, and over the period. Conclusion : The Journal of Korean Oriental Medicine needs to improve the quality its articles. To improve the quality of oriental medicine related articles, the following are necessary: working together, joint work of inter-educational system, strengthening of reviewer system, use of statistical methods, and consulting to the expert of research at the stage of study design.

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GABA Productivity in Yoghurt Fermented by Freeze Dried Culture Preparations of Lactobacillus acidophilus RMK567 (Lactobacillus acidophilus RMK567의 동결건조 컬쳐로 제조한 요구르트에서 GABA 생성력)

  • Lim, Sang-Dong;Yoo, Sung-Ho;Yang, Hae-Dong;Kim, Sang-Ki;Park, Seung-Yong
    • Food Science of Animal Resources
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    • v.29 no.4
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    • pp.437-444
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    • 2009
  • ${\gamma}-Aminobutyric$ acid (GABA) producing lactic acid bacteria, Lactobacillus acidophilus RMK567 was cultivated in 50 L of sterilized MRS broth using a fermenter at $40^{\circ}C$ for 24 h. The cell number was increased to $10.04{\pm}0.13$ Log CFU/mL with a growth rate constant (k) of 0.454 generation/h and a generation time (g) of 2.303 h after a lapse of a lag phase (L) of 5.16 h. A total of 487 g of cell paste with 40.5% moisture was harvested with viable cell number of 12.48 Log CFU/g cell paste. The cell pastes after preparation with glycerol, glucose, and polydextrose as cryo-protectants were lyophilized under a vacuum of 84 m torr. A total of 408 g of freeze dried (FD) cell powders were mixed with a commercial strain of Streptococcus thermophilus to prepare of three types FD starter cultures with the viable cell numbers of 12.42 (FDA-GY), 12.60 (FDBGG) and 12.91 (FDC-GP) Log CFU/g. During preservation the FD cultures at -$18^{\circ}C$, the cell viability of the FD starter cultures were rapidly dropped to below 3.24% of the day of storage. No significant difference was found in the cell viabilities among three types of FD starters cultures, but significant difference (p<0.01) was found in storage periods. Yoghurts fermented through FD starter culture of L. acidophilus RMK567 were determined to contain $155.16{\pm}8.53$ ppm, $243.82{\pm}4.27$ ppm, and $198.64{\pm}23.46$ ppm of GABA, respectively. This study shows that GABA production activity of L. acidophilus RMK567 is not affected during the freeze drying process and would be available for commercial production of yoghurt containing high GABA content.

Cryptosporidium spp., Giardia intestinalis, and Enterocytozoon bieneusi in Captive Non-Human Primates in Qinling Mountains

  • Du, Shuai-Zhi;Zhao, Guang-Hui;Shao, Jun-Feng;Fang, Yan-Qin;Tian, Ge-Ru;Zhang, Long-Xian;Wang, Rong-Jun;Wang, Hai-Yan;Qi, Meng;Yu, San-Ke
    • Parasites, Hosts and Diseases
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    • v.53 no.4
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    • pp.395-402
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    • 2015
  • Non-human primates (NHPs) are confirmed as reservoirs of Cryptosporidium spp., Giardia intestinalis, and Enterocytozoon bieneusi. In this study, 197 fresh fecal samples from 8 NHP species in Qinling Mountains, northwestern China, were collected and examined using multilocus sequence typing (MLST) method. The results showed that 35 (17.8%) samples were positive for tested parasites, including Cryptosporidium spp. (3.0%), G. intestinalis (2.0%), and E. bieneusi (12.7%). Cryptosporidium spp. were detected in 6 fecal samples of Macaca mulatta, and were identified as C. parvum (n=1) and C. andersoni (n=5). Subtyping analysis showed Cryptosporidium spp. belonged to the C. andersoni MLST subtype (A4, A4, A4, and A1) and C. parvum 60 kDa glycoprotein (gp60) subtype IId A15G2R1. G. intestinalis assemblage E was detected in 3 M. mulatta and 1 Saimiri sciureus. Intra-variations were observed at the triose phosphate isomerase (tpi), beta giardin (bg), and glutamate dehydrogenase (gdh) loci, with 3, 1, and 2 new subtypes found in respective locus. E. bieneusi was found in Cercopithecus neglectus (25.0%), Papio hamadrayas (16.7%), M. mulatta (16.3%), S. sciureus (10%), and Rhinopithecus roxellana (9.5%), with 5 ribosomal internal transcribed spacer (ITS) genotypes: 2 known genotypes (D and BEB6) and 3 novel genotypes (MH, XH, and BSH). These findings indicated the presence of zoonotic potential of Cryptosporidium spp. and E. bieneusi in NHPs in Qinling Mountains. This is the first report of C. andersoni in NHPs. The present study provided basic information for control of cryptosporidiosis, giardiasis, and microsporidiosis in human and animals in this area.

Ship′s Distance Measuring System by the GPS Receiver in Anchoring Watch (GPS 선간거리계측 시스템에 의한 묘박상황의 감시)

  • 김광홍;신형일
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.37 no.4
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    • pp.257-266
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    • 2001
  • It was set up MCS and MS of ship's distance measuring system in land and ship respectively and ship's track including dropped and hove up anchor was tracked by mean of measurement for ship's position, relative bearing and distance from MCS to MS. Results analyzed for possibility of real time anchoring watch and effectiveness of measuring position are as follow; (1) The elapsed time from dropped anchor to hove up anchor is 4 minutes and the elapsed time to start recording ship's track after set up anchoring state is 10 minutes approximately. (2) Shape of hull's swing during anchoring is mostly 8 figue-like or rarely peanut-like shape. (3) Mean anchoring position during whole measuring time was shifted 49m north and 89m eastly. (4) Ship's track were moved counter-clockwise for $8.1^\circ$ range from relative bearing $186.1^\circ$ to $194.2^\circ$ ellipse-like tracks with the major axis 63m and the minor axis 53m. (5) High frequency of ship's position distribution was shown at relative bearing $187^\circ$ and distance 558m while low frequency was shown at relative bearing $194^\circ$ and distance 556m. (6) The designed ship's distance measuring system by PRTK-GPS was fit very well for anchoring watch as secured necessary area demanded for dragging anchor as well as anchoring by means of real time measurement both in distance and bearing.

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