• Title/Summary/Keyword: gp41

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A Study on Application of Global Positioning System for Cadastral Surveying (지적측량을 위한 GPS의 활용방안에 관한 연구)

  • Yim, Hyon-Cheol
    • Journal of Korean Society for Geospatial Information Science
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    • v.15 no.4
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    • pp.41-50
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    • 2007
  • This study aims to suggest efficient setting up of GPS (Global Positioning System) for cadastral surveying. In order to perform it effectively, worldly used modern surveying technology GPS introduced. In a practical analysis, GPS observation had been performed in the research area and the results had been compared and analysed with the results of Total Station. As a results, it is shown that GPS is more efficient rather than current surveying method in terms of time, cost and economy. The results of GPS surveying were included in the scope of error tolerance, being accepted by cadastral laws, showing high accuracy of GPS surveying method. With the results of analysis, how to application of GPS for cadastral surveying was suggested.

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Effect on the Arginine Transport of Mutant MCAT1, Mouse Cationic Aminoacid Transporter (MCAT1의 돌연변이체가 Arginine 통과 능력에 미치는 영향)

  • Kim, Jung-Woo
    • The Journal of Natural Sciences
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    • v.8 no.2
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    • pp.35-41
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    • 1996
  • To find the substrate interacting site of the MCAT1, charged amino acid residues in the transmembrane domain were changed to opposite charged amino acids and studied the arginine uptake, gp70 binding, efflux and protein expression using the Xenopus oocyte expression method. Among the five mutants of MCAT1, the D403K showed the most interesting characteristics, which had normal gp70 binding but low arginine uptake function, that means the normal expression on the membrane but decreased transport function. All mutants except K211E showed decreased arginine efflux, and kinetic study showed decreased Vmax. Together, Clu(403) residue of MCAT1 may show the possible substrate interacting site in the transmembrane domain of MCAT1.

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Virus-cell fusion inhibitory compounds from Ailanthus altissima Swingle

  • Lee, Hyang-Hee;Chang, Young-Su;Moon, Young-Hee;Woo, Eun-Rhan
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.264.1-264.1
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    • 2003
  • In order to search for the anti-HIV agents from natural products, Eighty MeOH extracts of medicinal plants were applied to a syncytia formation inhibition assay which is based on the interaction between the HIV-1 envelope glycoprotein gp120/gp41 and the cellular membrane protein CD4 of T lymphocytes. Among them, Ailanthus altissima showed a potent virus-cell fusion inhibitory activity. (omitted)

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Quality and Sensory Characteristics of White Bread added with Various Ginseng Products (인삼제품의 첨가에 따른 제빵적성 및 관능평가)

  • Song, Mi-Ran;Lee, Ka-Soon;Lee, Byeong-Chan;Oh, Man-Jin
    • Food Science and Preservation
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    • v.14 no.4
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    • pp.369-377
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    • 2007
  • This study investigated the effect of ginseng products on the baking properties of white breads. Flour was substituted by ginseng products (ginseng at levels 2, 4, 6, and 8%, all w/w, of flour levels). Both ginseng powder (GP) and red ginseng powder (RGP) were used. Similarly, red ginseng extract (RGE) was substituted at levels of 1, 2, 3, and 4% (all w/w) of flour. The physical properties of each dough were assessed using farinograms, extensograms, and amylograms. Water absorption increased as the proportions of ginseng products rose. The dough surface areas and R/E (resistance/extensibility) values decreased, as did peak viscosities, at the proportions of ginseng products increased. The pH values during fermentation decreased as the proportions of ginseng products increased. The fermentation power of dough with GP was lower than that of control, and higher than that of dough with RGP or RGE, but the addition of ginseng products beyond certain levels weakened the gas retention power: The specific loaf volumes of breads with 2% GP were the highest at 5.41 mL/g. In breads with RGE, the specificloaf volume increased from 5.52 mL/g to 5.82 mL/g as RGE levels rose from 0% to 4%. Hardness increased with rising GP and RGP levels in breads with GP and RGP, but decreased with RGE levels in breads with RGE. The moisture contents of breads during storage tended to be higher than control in breads with ginseng products. Lightness increased with addition of GP and decreased upon addition of RGP or RGE, while redness and yellowness increased after addition of any ginseng products. In sensory evaluation tests, the sensory scores for texture, color, mouth feel, and overall acceptability, were high, when any ginseng product (GP, RGP or RGE) was present at 2%. Of these breads, the bread with 2% RGE attained the highest sensory score.

Virus-cell Fusion Inhibitory Activity for the Polysaccharides from Various Korean Edible Clams

  • Woo, Eun-Rhan;Kim, Wan-Seok;Kim, Yeong-Shik
    • Archives of Pharmacal Research
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    • v.24 no.6
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    • pp.514-517
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    • 2001
  • In order to find potent virus-cell fusion inhibitory components from Korean edible clams, thirteen prepared polysaccharides were introduced to syncytia formation inhibition assay, which is based on the interaction between the HIV-1 envelope protein gp 120/41 and the cellular membutane protein CD4 of T lymphocytes. Among them, Meretrix petechialis showed a potent viruscell fusion inhibitory activity. Fusion index (F1) and percent (%) fusion inhibition of the polysaccharide of this clam were $0.21{\pm}0.02$, and $67.52{\pm}4.09$ at 100781m1, respectively. It exhibited almost equivalent virus-cell fusion inhibitory activity to that of dextran sulfate which was used as a standard control.

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Effects of Silibinin on the Pharmacokinetics of Carvedilol after Oral Administration in Rats

  • Lee, Chong-Ki;Choi, Jun-Shik
    • Journal of Pharmaceutical Investigation
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    • v.41 no.3
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    • pp.153-159
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    • 2011
  • This study was designed to investigate the effects of silibinin on the pharmacokinetics of carvedilol after oral administration of carvedilol in rats. Carvedilol was administered orally (3 mg/kg) with oral silibinin (0.3, 1.5 or 6 mg/kg) and intravenously (1 mg/kg) to rats. The effects of silibinin on P-glycoprotein (P-gp) and cytochrome P450 (CYP) 2C9 and CYP2D6 activity were also evaluated. Silibinin inhibited CYP2C9 and CYP2D6 enzyme activity with 50% inhibition concentration ($IC_{50}$) of 5.2 ${\mu}M$ and 85.4 ${\mu}M$, respectively. In addition, silibinin significantly enhanced the cellular accumulation of rhodamine-123 in MCF-7/ADR cells overexpressing P-gp. Compared with the control group, the area under the plasma concentration-time curve was significantly increased by 36.3-57.1%, and the peak concentration was significantly increased by 51.1-88.5% in the presence of silibinin after oral administration of carvedilol. Consequently, the relative bio-availability of carvedilol was increased by 1.13- to 1.57-fold and the absolute bioavailability was significantly increased by 38.6-59.7%. The time to reach peak concentration and the terminal half-life were not significant. The enhanced oral bio-availability of carvedilol may result from inhibition of CYP2C9-mediated metabolism and P-gp-mediated efflux of carvedilol rather than inhibition of CYP2D6-mediated metabolism in the intestine and/or in the liver by silibinin.

Push-out bond strength and dentinal tubule penetration of different root canal sealers used with coated core materials

  • Sungur, Derya Deniz;Purali, Nuhan;Cosgun, Erdal;Calt, Semra
    • Restorative Dentistry and Endodontics
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    • v.41 no.2
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    • pp.114-120
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    • 2016
  • Objectives: The aim of this study was to compare the push-out bond strength and dentinal tubule penetration of root canal sealers used with coated core materials and conventional gutta-percha. Materials and Methods: A total of 72 single-rooted human mandibular incisors were instrumented with NiTi rotary files with irrigation of 2.5% NaOCl. The smear layer was removed with 17% ethylenediaminetetraacetic acid (EDTA). Specimens were assigned into four groups according to the obturation system: Group 1, EndoRez (Ultradent Product Inc.); Group 2, Activ GP (Brasseler); Group 3, SmartSeal (DFRP Ltd. Villa Farm); Group 4, AH 26 (Dentsply de Trey)/gutta-percha (GP). For push-out bond strength measurement, two horizontal slices were obtained from each specimen (n = 20). To compare dentinal tubule penetration, remaining 32 roots assigned to 4 groups as above were obturated with 0.1% Rhodamine B labeled sealers. One horizontal slice was obtained from the middle third of each specimen (n = 8) and scanned under confocal laser scanning electron microscope. Tubule penetration area, depth, and percentage were measured. Kruskall-Wallis test was used for statistical analysis. Results: EndoRez showed significantly lower push-out bond strength than the others (p < 0.05). No significant difference was found amongst the groups in terms of percentage of sealer penetration. SmartSeal showed the least penetration than the others (p < 0.05). Conclusions: The bond strength and sealer penetration of resin-and glass ionomer-based sealers used with coated core was not superior to resin-based sealer used with conventional GP. Dentinal tubule penetration has limited effect on bond strength. The use of conventional GP with sealer seems to be sufficient in terms of push-out bond strength.

Wearable Personal Security System Using GPS (GPS를 이용한 웨어러블 개인 안전 시스템)

  • 라혁주;김성주;최우경;김성현;전홍태
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2004.04a
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    • pp.38-41
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    • 2004
  • 납치ㆍ유괴는 개인의 자유로운 활동에 많은 영향을 미치는 위험요소이다. 이러한 위험 요소로부터 벗어나기 위해서 개인의 위치를 확인할 수 있는 시스템이 절실히 필요하다. 위성 항법 시스템(Global Positioning System, GPS)은 기상 상태에 상관없이 지구 전역에서 사용 가능한 효율적인 항법 시스템으로 위치정보에 대한 지표를 제공한다. GPS는 현재 지속적인 개발에 의해 수신 모듈의 소형화 고성능화가 이루어지고 있으며, 고정 또는 이동하는 시스템의 위치정보를 제공한다. GPS 시스템을 개인이 휴대하게 되면 개인의 이동경로를 확인할 수 있게 된다. 일반적으로 개인의 이동경로는 생활권역 내에 특정 지역으로 한정되는 경우가 많으며 이동경로 자체도 주된 교통수단과 맞물려 일정한 패턴을 형성한다. 이러한 이동특성에 착안하여 본 논문에서는 개인 안전을 위해 GPS의 위치정보와 소프트 컴퓨팅 기법을 접목한 시스템을 휴대한 사용자의 이동경로를 학습하여 개인의 안전을 보장하는 방법을 제안한다.

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