• Clinical and Experimental Pediatrics
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• v.57 no.9
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• pp.410-415
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• 2014

Purpose: Neurofibromatosis 1 (NF1) is an autosomal dominant condition caused by an NF1 gene mutation. NF1 is also a multisystem disorder that primarily affects the skin and nervous system. The goal of this study was to delineate the phenotypic characterization and assess the NF1 mutational spectrum in patients with NF1. Methods: A total of 42 patients, 14 females and 28 males, were enrolled in this study. Clinical manifestations and results of the genetic study were retrospectively reviewed. Results: Age of the patients at the time of NF1 diagnosis was $15.8{\pm}14.6$ years (range, 1-62 years). Twelve patients (28.6%) had a family history of NF1. Among the 42 patients, $Caf\acute{e}$-au-lait spots were shown in 42 (100%), neurofibroma in 31 (73.8%), freckling in 22 (52.4%), and Lisch nodules in seven (16.7%). The most common abnormal finding in the brain was hamartoma (20%). Mental retardation was observed in five patients (11.9%), seizures in one patient (2.4%), and plexiform neurofibromas (PNFs) in four patients (9.5%). One patient with PNFs died due to a malignant peripheral nerve sheath tumor in the chest cavity. Genetic analysis of seven patients identified six single base substitutions (three missense and three nonsense) and one small deletion. Among these mutations, five (71.4%) were novel (two missense mutations: p.Leu1773Pro, p.His1170Leu; two nonsense mutations: $p.Arg2517^*$, $p.Cys2371^*$; one small deletion: $p.Leu1944Phefs^*6$). Conclusion: The clinical characteristics of 42 Korean patients with NF1 were extremely variable and the mutations of the NF1 gene were genetically heterogeneous with a high mutation-detection rate.

• Korean Journal of Veterinary Research
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• v.47 no.4
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• pp.417-423
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• 2007

Serological surveillance programs in animal populations are becoming increasingly important to estimate prevalence of a specific disease and subsequently to document disease-free status in a region or a country. For these purposes, the programs need to be based on both theoretical and economical aspects from the designing phase. From Aujeszky's disease (AD)-eradication program point of view, group of animals (aggregates, herds) not individual animal is the more important sampling unit of concern. In this study the authors therefore attempted to compute an appropriate sample size tailored to a current surveillance program against AD, assuming that the goal of this program is either herd-level prevalence estimation or documentation of AD-freedom. For prevalence estimation, assuming a finite population with imperfect sensitivity (Se) and specificity (Sp) of ELISA kit for AD diagnosis, the number of herds present, expected herd prevalence, and desired accuracy for a certain level of confidence, sample size was estimated at herd-level in the first stage and individual animal-level in the second stage. A two-stage sampling design was used to calculate a sample size to indicate AD-freedom. In this instance, the computation was based on the possible detection of a predetermined prevalence at a certain herd-level Se and Sp. This study indicated that the sample size varied with predetermined confidence, tolerance, Se and Sp at herd- and animal-level, and within- and among-herd prevalence. In general, smaller sample size was required to estimate AD prevalence than to document of AD-freedom. Compared to individual-based samples, two-stage sampling strategy requires a larger sample size to show disease-freedom. Statistical considerations including herd-level test characteristics when designing surveillance program also are further discussed.

• Journal of the Korean Society for Nondestructive Testing
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• v.30 no.1
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• pp.1-5
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• 2010

Acoustic emission(AE) has emerged as a powerful nondestructive tool to detect or monitor preexisting defects and leaks in the vessel structures. A Bragg grating based acoustic emission sensor system is developed. Various type of fiber Bragg grating sensor including the variable length of sensing part was fabricated and prototype sensor system was tested by using PZT pulser and pencil lead break sources. Two types of sensor attachment were used. First, the fiber Bragg grating sensor was attached fully to the surface using bonding agent. Second one is that one part of fiber was attached to the surface partly by bonding and the other part of fiber will be act as a cantilever. That is, the resonant frequency of the fiber Bragg grating sensor will depend on the length of sensing part. The final goal of the sensor system is to provide on-line monitoring of cracks or leaks in reactor vessel head penetration of nuclear power plants.

• Journal of Broadcast Engineering
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• v.18 no.5
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• pp.680-690
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• 2013

In this paper, we propose a real-time temporal synchronization and compensation algorithm in stereoscopic video. Many temporal asynchronies are caused in the video editing stage and due to different transmission delays. These temporal asynchronies can degrade the perceived 3D quality. The goal of temporal alignment is to detect and to measure the temporal asynchrony and recover synchronization of the two video streams. In order to recover synchronization of the two video streams, we developed a method to detect asynchronies between the left and the right video streams based on a novel spatiogram information, which is a richer representation, capturing not only the values of the pixels but their spatial relationships as well. The proposed novel spatiogram additionally includes the changes of the spatial color distribution. Furthermore, we propose a block-based method for detection of the pair frame instead of one frame-based method. Various 3D experiments demonstrate the effectiveness of the proposed method.

• Quality Improvement in Health Care
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• v.3 no.1
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• pp.78-93
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• 1996

Background : The goal of this study was to establish the QA items and guidelines for preventing and improving of safety management. Therefore we investigated the nurses' recognition and knowledge of the safety and risk procedures and policies, and the agreement between the nurses beliefs on the degree of importance of those procedures and policies, with actual implementation in hospitals. Method : The subjects of this study were 201 nurses who participated in a program called continuing education for nurses, which held in December, 1993. Result: The results of this study were as follows: 1. Among 18 types of hospital risks, the items that scored highest or the need of closer attention in safety management was the needle stick, medication errors, falling, and bed sores. 2. In most questions of the 18 incidences, the nurses showed that the estimated result would have positive signs except for hospital infections, burns, and bed sores. 3. Even though the survey shows that incidences and types of occurences varies according to the person's age and the time of incident, they mostly occur between midnight to 6AM. Falls and bed sores can be seen more in the elderly. Medications errors, hospital infections and burns are frequently found between the ages of one through twenty. 4. There was a higher mean score for recognizing the importance of those items than the importance of implementing them. Conclusion : In summary, nurses did perceive the need of safety management but the hospital policy for proper safety management was not established. So we recommended that the hospital administration would undertake an early detection and proper management system for hospital precautions, based on QA items & guidelines presented in this study.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.5
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• pp.54-63
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• 2007

The purpose of this study is to present a new energy minimization method for image completion with hierarchical approach. The goal of image completion is to fill in missing part in a possibly large region of an image so that a visually plausible outcome is obtained. An exemplar-based Markov Random Field Modeling(MRF) is proposed in this paper. This model can deal with following problems; detection of global features, flexibility on environmental changes, reduction of computational cost, and generic extension to other related domains such as image inpainting. We use the Priority Belief Propagation(Priority-BP) which is a kind of Belief propagation(BP) algorithms for the optimization of MRF. We propose the hierarchical Priority-BP that reduces the number of nodes in MRF and to apply hierarchical propagation of messages for image completion. We show that our approach which uses hierarchical Priority-BP algorithm in image completion works well on a number of examples.

• The Transactions of the Korea Information Processing Society
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• v.6 no.10
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• pp.2563-2573
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• 1999

In most mail automatic processing centers, after facing and canceling, letter mails are passed through an Optical Character Recognition/Barcode Sorter(OCR/BS) to read the postal code and 3 of 5 fluorescent (luminescent) barcode is applied. Normally, 31%∼35% of this mails are rejected. The main reasons for reading failures are poor printing quality of addresses and barcodes, script printing, writing in a cursive hand, variety fonts, and failure to locate the address. Our goal is to provide mailer with top quality service and customer barcode service as we move toward 100% barcoding automation of letter mail. In this paper, we propose a method of printing 3 of 5 customer barcode, postal code management, and detection of postal code based on postal address for increase the performance of automatic processing system in mail items. Using postal code generating rules, which are automatically extracted from postal addresses and address numbers, creates postal codes. The customer barcode support system is implemented by C++ language and runs on IBM PC under Windows 95.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.19 no.8
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• pp.131-137
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• 2005

The purpose of this paper is to evaluate the axial magnetic flux measurement could be used as a tool of the condition monitoring system for the induction motor and to develope the diagnostic algerian for the electric motors. The magnetic leakage flux signal is captured by the flux coil located at the end of motor without the disturbance of the operation. And the signal is analyzed both time and frequency bases to detect the failure of the motor. Specific signature can be described in time and frequency domain for each faults of the motor. The spectrum of the signal was found more useful for the monitoring purpose. The supply voltage imbalance and tin to turn failure of the stator winding could be detected by analysing the specific sidebands of the axial flux and sideband of the rotor bar pass frequency with the high resolution spectrum. The goal of this study verity that the axial flux measurement for the induction motor is a powerful tool for the diagnostic method and develope the algorithm to detect the fault.

• Journal of the Korean Association of Geographic Information Studies
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• v.22 no.3
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• pp.133-145
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• 2019

Building and researching high definition maps that support autonomous vehicles, one of Korea's key challenges for the future, are being actively propelled in both private and government sectors with the goal of fast commercialization. Under this perspective, update methods that secure up-to-date information are emerging as key tasks. To provide a plan for establishing efficient renewal systems for high definition maps, we analyzed the present condition of road types, causes of road changes and its annual change rates, and examined where and how such road change information is managed. Furthermore, the method of collection and detection of road change information and the renewal system of high definition maps are defined based on the current study. At the end of the paper, a step-by-step renewal system is proposed through the examination of renewal cycles, contents, and region of high definition maps.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.35.4-35.4
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• 2019

We have conducted a 22 GHz very long baseline interferometry (VLBI) survey of 281 local (z < 0.05) active galactic nuclei (AGNs) selected from the Swift Burst Alert Telescope (BAT) 70-month ultra hard X-ray (14-195 keV) catalog. The main goal is to investigate the relation between the strengths of black hole accretion and the parsec-scale nuclear jet, which is expected to tightly correlate but has not been observationally confirmed yet. The BAT AGN Spectroscopic Survey (BASS) provides the least biased AGN sample against obscuration including both Seyfert types, hence it makes an ideal parent sample for studying the nuclear jet properties of an overall AGN population. Using the Korean VLBI Network (KVN), the KVN and VERA Array (KaVA), and the Very Long Baseline Array (VLBA), we observed 281 objects with a 22 GHz flux > 30 mJy, detecting 11 targets (~4% of VLBI detection rate). This implies that the fraction of X-ray AGNs which are currently ejecting a strong nuclear jet is very small. Although our 11 sources span a wide range of pc-scale morphological types, from compact to complex, they lie on a tight linear relation between accretion luminosity and nuclear jet luminosity. Our finding may indicate that the power of nuclear jet is directly responsible for the amount of black hole accretion. We also have probed the fundamental plane of black hole activity in VLBI scale (e.g., few milli-arcsecond). The results from our high-frequency VLBI radio study support that the change of jet luminosity and size follows what is predicted by the AGN evolution scenario based on the Eddington ratio (ƛ$_{Edd}$) - column density ($N_H$) plane, proposed by a previous study.