• Title/Summary/Keyword: glycerin

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In-vitro Tests of Topical Skin Protectants using a Flow-Through Diffusion Cell System Containing Excised Hairless Mouse Skin (생체 피부조직을 이용한 피부보호제 in-vitro 시험평가)

  • Lee, Eun Young;Choi, Hoo Kyun;Kim, Sang Woong;Seo, Dong Sung;Joe, Hae Eun;Yu, Chi Ho;Kim, Chang Hwan;Cho, Young
    • Journal of the Korea Institute of Military Science and Technology
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    • v.25 no.4
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    • pp.434-442
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    • 2022
  • Highly toxic chemical warfare agents(CWA) could be used in chemical warfare and terrorism. The protection of skin is crucial for civilians and soldiers, because the primary routes of exposure to CWA are inhalation and skin absorption. Thus, topical skin protectants(TSP) have been studied and developed in many countries to complement protective equipments. In this study, in-vitro test procedure was optimized and established using a flow-through diffusion cell system containing excised hairless mouse skin in an attempt to assess the effectiveness of various TSP formulations against nerve agent simulants. In addition, the test results on the formulations including the ingredients used in SERPACWA(Skin Exposure Reduction Paste Against Chemical Warfare Agent) and IB-1(TSP of Israel) were included, indicating that the formulations with perfluorinated compounds were more effective than the glycerin-based formulations.

Heat Transfer Characteristics of Tubular Thermal Reactor (관형 열반응기의 열전달 특성)

  • Yang, Hei-Cheon;Park, Sang-Kyoo;Ra, Beong-Yeol
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.1948-1952
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    • 2007
  • Heat transfer augmentation based on the process intensification concept in heat exchangers and thermal reactors has received much attention in recent years, mainly due to energy efficiency and environmental considerations. The concept consists of the development of novel apparatuses and techniques that, compared to those commonly used today, are expected to bring dramatic improvements in manufacturing and processing, substantially decreasing equipment size, energy consumption, and ultimately resulting in cheaper, sustainable technologies. The objective of this paper was to investigate the heat transfer characteristics of tubular thermal reactor using static mixing technology. Glycerin and water were used as the test fluids and water was used as the heating source. The results for heat transfer rate were strongly influenced by tube geometry and flow conditions.

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Improving Process Capability by 2-Way Classification (2원배치법(元配置法)을 이용한 공정능력(工程能力)의 향상(向上))

  • Gu, Bon-Cheol;Song, Seo-Il
    • Journal of Korean Society for Quality Management
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    • v.17 no.2
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    • pp.64-69
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    • 1989
  • This paper aims at analyzing the process capability and at determining an optimal condition by experimental designs using the 2-way classification with repitition in order to maintain lower Nacl content and to refine both of a very small quantity of fatty acid and various magnetic ions in the glycerin to use ion exchange resin treatment process. An optimal condition of each level combination in both of passing temperature of cation exchange resin($A_1$, $A_2$, $A_3$) and of anion exchange resin($B_1$, $B_2$, $B_3$) is $A_3B_3$. The process capability index is improved from 0.63 to 1.40 and is interpreted as a desirable state. This analysis of process capability by experimental designs will contribute to improving productivity and quality of products.

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A Novel Viscosity Measurement Technique Using a Falling Ball Viscometer with a High-speed Camera

  • Jo, Won-Jin;Pak, Bock-Choon;Lee, Dong-Hwan
    • KSTLE International Journal
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    • v.8 no.1
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    • pp.16-20
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    • 2007
  • This study introduces a new approach to a falling ball viscometer by using a high speed motion camera to measure the viscosity of both Newtonian and non-Newtonian fluids from the velocity-time data. This method involves capturing continuous photographs of the entire falling motion of the ball as the ball accelerates from the rest to the terminal velocity state. The velocity of a falling ball was determined from the distance traversed by the ball by examining video tape frame by frame using the marked graduations on the surface of the cylinder. Each frame was pre-set at 0.01. Glycerin 74% was used for Newtonian solution, while aqueous solutions of Polyacrylamide and Carboxymethyl Cellulose were for non-Newtonian solutions. The experimental viscosity data were in good agreements with the results obtained from a rotating Brookfield viscometer.

Value Addition Span of Silkworm Cocoon - Time for Utility Optimization

  • Reddy, R. Manohar
    • International Journal of Industrial Entomology and Biomaterials
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    • v.17 no.1
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    • pp.109-113
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    • 2008
  • Realizing the scope of utilizing by-products of silk cocoons by applying appropriate methods is the immediate crave to optimize returns. The nutritive value of pupae suits for human diet, feed for poultry, carps, fish, rabbits, piggery and dogs. The pupal skin, fat, oil, cocoon palade have applications in oleo chemical, soap, glycerin, cosmetic, artificial fibres, membranes and n-triacontanol isolation. The pupal proteins Chitin, Shinki fibroin, Serrapeptidase, glucosamine are latent precursors of post surgical, anti-carcinogenic, anti-inflammative, anti-bacterial, anti-histaminic, gastric, hepatitis, pancreatitis, leukocytopenia, neurological, ophthalmic, blood pressure, cardiac and diabetic medicines and for preparation of vitamins A, E and K. The silk and its proteins sericin and fibroin are potentially used for wound healing, diabetes, impotence, sinusitis, arthritis, edema, cystitis, epididymitis, tissue regeneration, cancer, post-surgical trauma and used as anti-oxidatives, bio-adhesives, ultra violet screens and bio-active textiles. The waste cocoons can be used in making art crafts like garlands, carpets, overcoats, decoratives and greeting cards. The in-depth research towards utility optimization and make aware this reality to sericulturists, reelers, weavers, traders, entrepreneurs, policy makers etc., is the upright want of the today's Sericulture industry.

Solubilization of Ibuprofen in Aqueous Solution (이부프로펜의 가용화)

  • Lee, Jang-Won;Park, Eun-Seok;Chi, Sang-Cheol
    • Journal of Pharmaceutical Investigation
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    • v.27 no.4
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    • pp.279-286
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    • 1997
  • In order to formulate 2% ibuprofen solution, the effects of various solublizing agents, such as cosolvents (propylene glycol, polyethylene glycol, glycerin), a complexing agent $(CELDEX{\circledR}\;CH20)$, surfactants $(Poloxamers\;and\;Cremophor{\circledR}\;RH40)$ on the solubility of ibuprofen in aqueous solution were evaluated. Among them, Poloxamer 407 and $Cremophor{\circledR}$ RH40 showed the excellent capacity on the solubilization of ibuprofen. After 2% ibuprofen solution of choice were administered orally to rats, in reference to a 2% ibuprofen syrup in the market, the pharmacokinetic parameters were determined. The absorption rate of ibuprofen from the solution was higher than that from the suspension.

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A Study of Transparent Liquid Crystal Gel with High Oil Content from Fatty Acid Soap (지방산 솝을 이용한 고오일 함유 투명젤 생성에 관한 연구)

  • Lee, Jung-No;Kim, Hyuk-Hwa;Yu, Kang-Yeol
    • Journal of the Korean Applied Science and Technology
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    • v.28 no.4
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    • pp.431-437
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    • 2011
  • Transparent liquid crystal gels with high oil content by fatty acid soap were investigated. The solubilization efficiency of the mineral oil was dependent on the process. The process of dropping water part into the solution of oil and surfactant was more efficient than the process of dropping water part into the surfactant solution and after that dropping oil. The fatty acid soap could not solubilize the high oil content, but under the certain range, addition of CDE (Coconut Diethanolamide), Arlacel 165 (Glyceryl Stearate/PEG-100 Stearate) and cetostearyl alcohol helped solubilize the high content oil. Also, the glycerin and water content had influence on the solubilization. Especially, higher oil content gel showed elastic feature.

Studies on the Lipase Produced by Alkalophilic Microorganism (Alkalophilic microorganism이 생산하는 lipase에 관한 연구)

  • Jeong, Kwang-Seon;Ham, Cheol-Joo;Shin, Won-Cheol
    • Journal of Industrial Technology
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    • v.7
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    • pp.59-68
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    • 1987
  • In order to obtain a strain of producing lipase which has resistance against alkaline and detergent, a screening test was carried out. Among 500 strains isolated from soil samples, the strain J-19 was selected for this study. The composition of the optimum medium for the highest lipase production was 2.0% glycerin, 1.0% corn steep liquor, 2.0% yeast extract, 0.1% $MgSO_4$ $7H_2O$, 0.2% $K_2HPO_4$, 1.5% soybean oil and 0.1% LAS(linear alkylbenzene sulfonate) with initial pH value of 10.0 and 3-day cultivation at $25^{\circ}C$. The lipase activity of the strain J-19 under optimal condition was 3.3. units/ml, which was increased about 1.3-fold than that of basal medium.

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A Study for the Pressure Drop of Static Mixers (스태틱 믹서의 압력손실에 대한 연구)

  • 양희천;박상규
    • Journal of Advanced Marine Engineering and Technology
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    • v.27 no.2
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    • pp.299-304
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    • 2003
  • Static mixer consists of a straight pipe of circular cross section into which individual elements are inserted to cut, fold, twist and re-combine the mixing fluid. The number of elements and their shape required in any application depend on the complexity of the mixing process. The objectives of this study are to develop a new static mixer and to perform the experimental investigation of pressure drop in order to evaluate the performance of the new one. The mixing fluid used is Glycerin. The pressure drop is measured using a hydraulic manometer and the correlation of Z-factor is suggested as a function of Re. The Z-factors of SSC and YNU mixer are about 40% lower than and 4% higher than that of the Sulzer one.

A Study of Flow and Mixing in a Static Mixer (스태틱 믹서의 유동 및 혼합에 대한 연구)

  • Yang, Hei-Cheon;Park, Sang-Kyoo;Eom, Yong-Suk;Ra, Byeong- Yeol
    • Proceedings of the KSME Conference
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    • 2001.11b
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    • pp.557-562
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    • 2001
  • Fluid mixing is ubiquitous and essential in many natural and industrial systems. Understanding the mixing processes that occur in these diverse system is essential for predicting many aspects of practical importance. The objective of this study is to perform the experimental and numerical investigation of the flow and mixing in a static mixer. Three different types of mixing elements, Sulzer, SSM and PPM were used. Glycerin and hydraulic oil were used as mixing fluids. Pressure drop was measured using a manometer.

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