• Journal of Periodontal and Implant Science
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• 제29권3호
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• pp.577-594
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• 1999

The major cause of periodontal disease is microorganism in the dental plaque. Gingival sulcular fluid, which is exudate released from the tissue near crevicular epithelium is related with inflammation. The purpose of this study was to evaluate the argon laser efficiency between the clinical index and onset of collagenase of gingival sulcular fluid. Material divided 16 patients into 4 groups. The first control was without treatmemt. The second was with just treatment of argon laser, The third was treated by scaling and root planning and the fourth was treated with both scailing and root planning and argon laser. The level of periocheck test, the index of bleeding, and the depth of periodontal pocket were evaluated from for 128 teeth of 64 anterior teeth and 64 posterior teeth. The results were as follows ; 1. In the score of periocheck test, root planing group(group 3) was significantly reduced more than the group without treatment(group 1) and the argon laser treatment(group 2) for results of 3 days and 7 days. But root planing plus argon laser treatment(group 4) in the 7days after experiment, was significantly reduced than no treatment(group 1) and root planing treatment(group 3)(P<0.05), in the 3 days after experiment, was significantly reduced than root planing(group3)(P<0.05). The score of periocheck test to the root planning group(group 3) were significantly reduced between days1, day3 and day7(P<0.05). Root planning plus argon laser group(group 4) were significantly reduced to 1 or 7days and 3 or 7days(P<0.05). The argon laser group(group 2) didn't show any changes. 2. In the case of sulcus bleeding index, the root planning group(group 3) and root planning plus argon laser group(group 4) were reduced more than without treatment group(group 1)(P<0.05) and sulcus bleeding index in the root planning group(group 3) were reduced more than the argon laser group(group 2)(P<0.05). 3. There wasn't any changes of pocket depth between the control and the experiment group as with experiment periods also.

• Journal of Periodontal and Implant Science
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• 제27권3호
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• pp.603-619
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• 1997

레이저를 이용한 연조직 수술은 출혈이 없어 시야를 좋게 하고 시술시간이 단축되며, 술후 종창이 최소화 되고, 통증이 감소화 최소화된 반흔 형성, 그리고 레이저가 조사되는 일부 부위의 멸균효과등이 장점이 있어 최근에 의학분야 및 치의학분야에서 많이 사용되는 추세에 있다. 이에 본 연구에서는 $CO_2$레이저를 이용한 백서의 치은절제술시의 치유과정과 레이저 출력을 달리 하였을때의 치유과정을 관찰하기 위해, 백서의 상악전치의 치은조직에서 치은절제술 효과를 얻을 수 있는 최소 출력인 4watts를 이용한 부위를 대조군으로, 6watts를 이용한 부위를 실험군으로 하여, 술후 2일, 3일, 1주, 3주후에 각각 실험동물을 희생시켜 치유결과를 조직학적으로 비교 관찰하여 다음과 같은 결과를 얻었다. 대조군과 실험군 모두에서 2일째에서만 작은 크기의 혈병이 관찰되었고, 그 이후에서는 관찰되지 않았다. 2. 염증세포 침윤지역 크기는 대조군과 실험군 모두에게 2일째 가장 컸으며, 그 크기는 시간이 경과될수록 줄어들어 2주째는 거의 소실되었으며, 실험군의 경우 대조군에 비해 2,3째까지 크기가 더 컸으나, 1주째부터는 크기의 차이가 관찰되지 않았다. 3. 육아조직은 대조군, 실험군 모두 시간의 경과에 따라 점점 성숙되어, 2주째부터는 거의 정상 치은 결합조직으로 대체되는 소견을 보였고, 3주째에서는 완전한 치유양상을 보였다. 실험군의 경우 대조군보다 3일째까지는 그 크기가 더 컸으나 1주째부터는 크기의 차이가 없다. 4. 대조군과 실험군 모두에게 치은의 상피화하는 2일째에서 시작되는 소견을 보였고, 1주부터 상피돌기와 부분적인 접합상피의 재생이 관찰되었으며, 2주째부터는 구강열구상피의 각화가 시작되어 3주째에는 각화의 완성이 관찰되었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권2호
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• pp.132-136
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• 2000

The cell surface glycoprotein CD44 is a kind of adhesion molecule, which binds hyaluronic acid, type I collagen and fibronectin. Although there have been numerous reports on the expression and the function of CD44 in lymphocytes and macrophages, very little is known about its distribution and definite role in epithelial tissue, especially in oral epithelial one. The present study was performed to investigate the distribution and expression of the CD44 in human gingiva and squamous cell carcinoma(SCC) arising in human gingiva. And the authors compared CD44 expression with histopathologic grade of SCC. The results were as follows: 1. The CD44 was strongly expressed in granular, spinous and basal layers of normal marginal and attached gingiva, in spinous and basal layers of normal sulcular gingiva, and in all epithelial layers of normal junctional gingiva. 2. In SCC of gingiva, the CD44 was expressed in all but one case. In most of the cases the CD44 was expressed at cell membrane and the degree of expression was relatively strong. 3. In low-grade SCC of gingiva, the CD44 was strongly expressed, especially at the basal and spinous layers of abundantly keratinized cancer nests. In high-grade SCC of gingiva, the CD44 expression tended to be weak but was strong at cells showing individual keratinization. This study suggest that the CD44 expression of normal and cancerous gingival epithelium is associated with the degree of proliferation and differentiation of epithelial cells.

• 대한치과교정학회지
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• 제53권2호
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• pp.125-136
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• 2023

Before progress was recently made in the application of temporary anchorage devices (TADs) in bio-mechanical design, orthodontists were rarely able to intrude molars to reduce upper posterior dental height (UPDH). However, TADs are now widely used to intrude molars to flatten the occlusal plane or induce counterclockwise rotation of the mandible. Previous studies involving clinical or animal histological evaluation on changes in periodontal conditions after molar intrusion have been reported, however, studies involving human histology are scarce. This case was a Class I malocclusion with a high mandibular plane angle. Upper molar intrusion with TADs was performed to reduce UPDH, which led to counterclockwise rotation of the mandible. After 5 months of upper molar intrusion, shortened clinical crowns were noticed, which caused difficulties in oral hygiene and hindered orthodontic tooth movement. The mid-treatment cone-beam computed tomography revealed redundant bone physically interfering with buccal attachment and osseous resective surgeries were followed. During the surgeries, bilateral mini screws were removed and bulging alveolar bone and gingiva were harvested for biopsy. Histological examination revealed bacterial colonies at the bottom of the sulcus. Infiltration of chronic inflammatory cells underneath the non-keratinized sulcular epithelium was noted, with abundant capillaries being filled with red blood cells. Proximal alveolar bone facing the bottom of the gingival sulcus exhibited active bone remodeling and woven bone formation with plump osteocytes in the lacunae. On the other hand, buccal alveolar bone exhibited lamination, indicating slow bone turnover in the lateral region.