• Title/Summary/Keyword: gestation

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The relationship between eosinophilia and bronchopulmonary dysplasia in premature infants at less than 34 weeks' gestation

  • Yang, Joo Yun;Cha, Jihei;Shim, So-Yeon;Cho, Su Jin;Park, Eun Ae
    • Clinical and Experimental Pediatrics
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    • v.57 no.4
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    • pp.171-177
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    • 2014
  • Purpose: Eosinophilia is common in premature infants, and its incidence increases with a shorter gestation period. We investigated the clinical significance of eosinophilia in premature infants born at <34 weeks gestation. Methods: We analyzed the medical records of premature infants born at <34 weeks gestation who were admitted to the neonatal intensive care unit at Ewha Womans University Mokdong Hospital between January 2003 and September 2010. Eosinophilia was defined as an eosinophil percentage of >3% of the total leukocytes. Perinatal parameters and clinical parameters were also analyzed. Results: Of the 261 infants born at <34 weeks gestation, 22.4% demonstrated eosinophilia at birth. The eosinophil percentage peaked in the fourth postnatal week at 7.5%. The incidence of severe eosinophilia increased after birth up to the fourth postnatal week when 8.8% of all patients had severe eosinophilia. Severity of eosinophilia was positively correlated with a lower gestational age, birth weight, and Apgar score. Respiratory distress syndrome, bronchopulmonary dysplasia, nephrocalcinosis, intraventricular hemorrhage, and sepsis were associated with a higher eosinophil percentage. The eosinophil percentage was significantly higher in infants with bronchopulmonary dysplasia from the first postnatal week and the percentage was the highest in the fourth postnatal week, with the maximal difference being 4.1% (P<0.001). Conclusion: Eosinophilia is common in premature infants and reaches peak incidence and severity in the fourth postnatal week. The eosinophil percentage was significantly higher in bronchopulmonary dysplasia patients from the first postnatal week. Severe eosinophilia was significantly associated with the incidence of bronchopulmonary dysplasia even after adjusting for other variables.

AN ELECTRON MICROSCOPIC STUDIES OF RADIATION EFFECTS ON THE ENAMEL DEVELOPMENT OF THE RAT MOLAR (방사선조사가 백서구치법랑질발육에 미치는 영향에 관한 전자현미경적 연구)

  • Cho Hyo-Suck;You Dong-Soo
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.25 no.2
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    • pp.483-499
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    • 1995
  • Mandibular first molars of the rats were undertaken to observe the radiosensitivity of amelogenesis. Twenty four Sprague-Dawley rats received 396cGy radiation with the MK Cell irradiator using Cs-137, and twenty four rats served as control. They were devided into two groups; Group 1 which received radiation at the 14th day after gestation and group 2 which received radiation at the 19th day after gestation. Light Microscopy and Transmitted Electron Microscopy investigation was undertaken in the group 1 at the 15th, 18th, 20th, 22nd(2 days after birth), and 25th day(5 days after birth) after gestation, and in the group 2 at the 21th(birth day), 22nd(2 days after birth), and 25th(5 days after birth) day after gestation. The following histopathologic findings were obtained. 1. Compared with control group, experimental group showed a delayed formation of enamel and dentin due to slow rate of differentiation of undifferentiated mesenchymal cells. 2. In the experimental groups, the arrangement of the inner enamel epithelium was irregular and there were many vacuoles in the cytoplasm. There were dilated rER and mitochondria, increase of the intercellular space, and loss of the cellular polarity. 3. In the group 1, early enamel without Tomes' process, and early organic matrix was observed at the 25th day after gestation. 4. In the group 2, histopathologic changes were similar to those of the group 1, but the degree of changes was more severe than that of the group 1.

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A Case of Fetal Mummification and Lithopedion from a Bitch with Prolonged Gestation over about One Month (장기임신 개에서 발생한 태아미이라변성 및 석아의 1례)

  • 김용준;박영재;오홍근;한종현;이창민;강미선
    • Journal of Veterinary Clinics
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    • v.17 no.1
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    • pp.238-242
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    • 2000
  • A six-year old bitch pregnant with prolonged gestation over about one month was ovariohysterectomied. The bitch was proved to be normal by physical and biochemical examination and had not a purulent vaginal discharge. A large firm mass was palpated in left caudoventral abdomen. Radiography identified the mass as a fetus. The abdominal ultrasono-graphy identified the fetus was dead. Caesarian section through the median raphe over linea alba was attempted. Adhensions were found between the uterus, stomach, spleen, urinary bladder, and abdominal viscera. Two fragments of bone were found in the abdominal cavity because of rupture of left uterine horn. Radiography and ultrasonography were proved to be of use to diagnose prolonged fetal mummification. Ovario-hysterectomy was considered to be choice of treatment to remove the prolonged mummified fetus.

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A Morphological Study on the Development of the Placenta of the Golden Hamster (Mesocricetus auratus) (Golden Hamster (Mesocricetus auratus) 의 태반형성(胎盤形成)에 관한 형태학적(形態學的) 연구(硏究))

  • Lee, Cha Soo
    • Korean Journal of Veterinary Research
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    • v.13 no.2
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    • pp.111-118
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    • 1973
  • The placentation in the golden hamster (Mesocricetus auratus) and the morphological changes occuring in its placenta from implantation to parturition have been observed by light microscope. The results obtained were summarized as follows. 1. The development of the placenta in the fertilized ovum implanted on the day 5 of gestation was described with increasing gestational age. 2. On the day 8 of gestation, the chorioallantoic placenta was formed by fusion of the allantois to the chorion of ectoplacental cone. 3. On the day 13 of gestation, Reichert's membrane with the parietal yolk sac disappeared in a circumscribed area antimesometrially.

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Parametric Study for Optimum Shape of Gestation Stall Structures (임신돼지용 스톨 구조물의 최적형상을 위한 파라미터 해석)

  • Son, Byung Jik
    • Journal of the Korean Society for Advanced Composite Structures
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    • v.7 no.1
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    • pp.39-44
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    • 2016
  • This study analyzes gestation stall structures with high strength concrete. The ANSYS program described in this paper is effective not only because it shows good accuracy but also it shows the goodness of parameter studies by using APDL(ANSYS Parametric Design Language). We have performed the various parameter studies by thickness change. The results is presented by using contours and tables. The analysis results showed that it was effective to increase the height thickness(tz) rather than longitudinal thickness(tx).

EFFECT OF TIME DELAY IN AN AUTOTROPH-HERBIVORE SYSTEM WITH NUTRIENT CYCLING

  • Das, Kalyan;Sarkar, A.K.
    • Journal of applied mathematics & informatics
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    • v.5 no.3
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    • pp.597-606
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    • 1998
  • In the present study we consider a mathematical model of a non-interactive type autotroph-herbivore system in which the amount of autotroph biomass consumed by the herbivore is assumed to follow a Holling type II functional response. We have also incorpo-rated discrete time delays in the numerical response term to represent a delay due to gestation and in the recycling term which represent a delay due to gestation and in the recycling term which represents the time required for bacterial decomposition. We have derived con-dition for global asymptotic stability of the model in the absence of delays. Conditions for delay-induced asymptotic stability of the steady state are also derived. The length of the delay preserving stability has been estimated and interpreted ecologically.

Development on the esophagus of fetuses and neonates in Korean native goats (한국재래산양의 태아 및 신생아의 식도 발달에 관하여)

  • Jung, Soon-hee;Kim, Chong-sup;Huh, Chan-kwen
    • Korean Journal of Veterinary Research
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    • v.34 no.4
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    • pp.679-686
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    • 1994
  • The development of esophagus in fetuses between 60, 90, 120 days of gestation and neonates of Korean native goats was investigated by light, scanning electron microscopy. The results were summarized as follows; 1. The esophageal wall appeared to be differentiated into the epithelium, lamina propria, tunica muscularis and tunica adventitia at 60 days of gestation. The esophageal epithelium was stratified cuboidal at 60 days, being transformed into stratified squamous epithelium at 90 days, and completely transformed into squamous epithelium an 120 days. 2. In scanning electron microscopy, the longitudinal furrows and ridges appeared on the epithelium of the esophagus of the fetuses at 60 days of gestation. The longitudinal furrow became deeper and microplicae appeared in 90-day-old fetuses. The transverse and longitudinal folds appeared on the epithelial surface of esophagus and the esophageal epithelium started to be keratinized in the neonates.

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Studies on the Changes of Reproductive Organs, Serum Sex Hormones and Metabolites according to the Gestation Period in Rabbit (가토(家兎)의 임신(姙娠)에 따른 생식기관(生殖器官), 혈중(血中) 성(性)Hormone 및 대사물질(代謝物質)의 변화(變化)에 관(關)한 연구(硏究))

  • Lee, Kyu Seung;Han, Sung Wook;Park, Chang Sik
    • Korean Journal of Agricultural Science
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    • v.9 no.1
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    • pp.303-313
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    • 1982
  • The study was conducted to find out the concentrations of sex hormones and the contents of metabolites in serum, and the changes of weights and tissues on ovary, thyroid gland and adrenal gland according to gestation period in rabbit. The results were summarized as follows: 1. The ovary weights were increased significantly with the time e lapse after gestation and recovered normally at 5 days after parturition. In the histological changes of ovary, the lutein cells were hypertrophied and the secretory granules were increased actively until 3 weeks after gestation, and then a trophied thereafter. 2. The thyroid gland weights at all observation times were higher than those in control group, and the significance was recognized at 1, 3 and 4 weeks after gestation. The histological features of the secretory epithelium were the hyper trophic and columnar condition stimulating the functional state from 1 week after gestation. 3. The adrenal gland weights in experimental group were recognized significantly at 4 weeks after gestation, but showed higher than those in control group at all observation times. The zona fasciculata and zona reticularis of the gland showed the slight hypertrophic condition, but the zona glomeerulosa and adrenal medulla did not find out any particular changes. 4. The serum concentrations of progesterone and LH reached a peak level at 2 weeks and 1 week after geestation respectively, and rapidly began to decline thereafter. 5. The serum concentrations of estradiol-$17{\beta}$ and FSH were not detected below 20.0 pg/ml and 1.3 mIU/ml respectively. 6. The contents of total protein and non-protein nitrogen nitrogen were decreased gradually with the time elapse after gestation, but the significant differences were recognized from 3 weeks. 7. The total lipids were not changed markedly until 3 weeks, but increased significantly at 4 weeks after gestation and at 5 days after parturition. 8. The serum cholesterol tended to be decreased until 3 weeks, but increased at 4 weeks after gestation and at 5 days after parturition. 9. The serum calcium showed a continuous decrease during the gestation period, but the significant differences were recognized at 3 and 4 weeks. The serum phosphorus also had a significant decrease at 4 weeks after gestation.

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Effects of dietary energy levels on physiological parameters and reproductive performance of gestating sows over three consecutive parities

  • Jin, S.S.;Jin, Y.H.;Jang, J.C.;Hong, J.S.;Jung, S.W.;Kim, Y.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.3
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    • pp.410-420
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    • 2018
  • Objective: This experiment was to evaluate the effects of the dietary energy levels on the physiological parameters and reproductive performance during gestation over three parities in sows. Methods: A total of 52 F1 gilts ($Yorkshire{\times}Landrace$) were allotted to one of four dietary treatments using a completely randomized design. The treatments contained 3,100, 3,200, 3,300, or 3,400 kcal of metabolizable energy (ME)/kg diet but feed was provided at 2.0, 2.2, and 2.4 kg/d in the first, second and third parity, respectively. Results: The body weight and body weight gain during gestation increased as the dietary energy level increased (p<0.05, and p<0.01) in the first parity. In the second parity, the body weight of sows was the lowest (p<0.05) when 3,100 kcal of ME/kg treatment diet was provided. The body weight was higher as the dietary energy level increased (p<0.05) during the gestation period in the third parity. During lactation, the voluntary feed intake of lactating sows tended to decrease when gilts were fed higher energy treatment diet (p = 0.08) and the body weight, body weight gain were increased by dietary energy level during gestation (p<0.05). Backfat thickness was not affected by dietary treatment during the gestation period in three parities, interestingly backfat change from breeding to d 110 of gestation was higher as the dietary energy level increased at the first parity (p<0.05). When gilts were fed 3,400 kcal of ME/kg treatment diet a higher number of weaning piglets was observed in the first parity (p<0.05). The highest culling rate (69%) was seen when gestating sows were fed 3,100 kcal/kg ME treatment diet during three parities. Conclusion: In conclusion, the adequate energy intake of gestating sows should be 6,400 or 6,600 kcal of ME/d, 7,040 or 7,260 kcal of ME/d, and 7,680 or 7,920 kcal of ME/d for parity 1, 2, and 3, respectively.

Mineral Metabolism in Singleton and Twin-pregnant Dairy Goats

  • Harter, C.J.;Castagnino, D.S.;Rivera, A.R.;Lima, L.D.;Silva, H.G.O.;Mendonca, A.N.;Bonfim, G.F.;Liesegang, A.;St-Pierre, N.;Teixeira, I.A.M.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.1
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    • pp.37-49
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    • 2015
  • During pregnancy, the maternal body undergoes significant physiological changes. The present study assessed the changes on calcium (Ca), phosphorus (P), magnesium (Mg), sodium (Na) and potassium (K) metabolism in singleton and twin-pregnant dairy goats. The 42 goats used ($49.5kg{\pm}7.6$ body weight [BW]) were assigned at random to treatments that were factorially arranged to account for 2 breeds (Oberhasli and Saanen), 2 pregnancy types (singleton and twin) and 3 gestation periods (80, 110, and 140 days). Digestibility trials were performed at 80, 110, and 140 days of gestation. Mineral retention during pregnancy was determined in the maternal body, femur, uterus, mammary gland, fetus and fetal fluid. Blood samples were taken during pregnancy before and after a meal, and Ca, P, Mg, Na, K ions and alkaline phosphatase activity determined in serum. Bone mineral density was determined in the right femur. Statistical analyses were performed using the SAS MIXED procedure. Dry matter intake decreased linearly up to 140 days of gestation. Maternal BW gain, and Ca, P, and Mg retention (g/kg) decreased linearly with the advance of gestation days. Macromineral retention in maternal body (g/kg) was greater in Oberhasli than Saanen goats, and their fetuses had higher Ca, P, and Mg deposition (mg/g). Mineral retention (mg/g) increased in fetuses according to pregnancy development, with no differences between singleton and twin pregnancy. In the mammary gland, the retention of all minerals (g) increased with the days of pregnancy. In conclusion, related to Ca, P, and Mg metabolism can be divided into two stages. Up to 80 days of gestation, was characterized by the preparation of the maternal body reserves for future mineral demands. From 80 days of gestation onward, was characterized by the transfer of maternal body reserves for fetal development and colostrum production. Na and K supply was provided by adjustments in endogenous excretion and an increase in intestinal absorption. Finally, mineral metabolism was specific to each genotype and, except for Na, was not affected by the number of fetuses.