• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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• pp.281-288
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• 1998

Ginseng saponin from different part of Ginseng and 7 kinds of ginsenosides effect on immnotuncition of young and old mice. There have up-regulation effect in vivo and in vitro experiments for low function of old mice, but not up-regulation effect at normal immuno-function of young mice. That means "Adaptogens" of Ginseng saponin. Not appositions effect at Pg1 and Rb1 and have find, that effect relations with molecular weight of ginsenosides.senosides.

• International Journal of Industrial Entomology and Biomaterials
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• 제47권2호
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• pp.73-78
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• 2023

Currently, Hyphantira cunea Drury, the fall webworms (FWW), is one of the most severe insect pest for various landscaping trees and mulberry trees. In this study, we investigated whether FWW might be managed by Sodium saccharin (SAC) which is a food additive and not toxic to humans and environment. We found that FWW larvae treated with various concentrations of SAC showed dose-dependent delayed development and low survival rates. The lethal-concentration 50% of FWW larvae to SAC was 0.03 M. We also confirmed that SAC can be used to control FWW larvae attacking mulberry trees in the field. Compared to not-treated or tap-water-spraying control groups, SAC-spraying groups showed significantly higher mortality rates of FWW larvae (56.2%). Thus, SAC can be used for control FWW larvae in mulberry trees.

• 한국영양학회:학술대회논문집
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• 한국영양학회 1994년도 춘계학술대회
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• pp.663-665
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• 1994

• 노인간호학회지
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• 제20권sup1호
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• pp.119-126
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• 2018

Purpose: The aim of this study was to describe problems and solutions for older adults living alone and using wearable devices to report depressive moods in daily life. In addition, gerontology nurses' competencies and strategies were discussed based on lessons learned from the observational study. Methods: A hybrid method was used, combining literature review and content analyses based on interviews with 53 participants and observations done by the research team. Results: Main issues and relevant strategies were identified in terms of (1) applicability of information and communications technology (ICT) devices for older adults, (2) feasibility of older adults' use of ICT devices, (3) integration of ICT devices into daily life, and (4) relevant issues when older adults use ICT. Important roles and competencies were discussed regarding general and gerontology aspects of ICT. Conclusion: Findings indicate that a wearable device is feasible to measure daily depressive moods in older adults living alone in community settings. To extend our research protocol to practice, gerontology nurses must adequately prepare to meet emerging health care trends and end users' needs for ICT-based nursing. It is necessary to develop diverse educational programs and active involvement in research and design of relevant devices and programs.

• 동의생리병리학회지
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• 제18권6호
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• pp.1580-1584
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• 2004

On the basis of the widely collected fork prescriptions, long clinical practice of himself, together with integration of all the good points of earlier medical specialists, 孫思邈 wrote 『千金方』 of thirty volumes. Among them Volumes 『食治』 (Food Therapy) and 『養性』(Cultivating the Character) are especially meaningful for in gerontology. Thirty years after its completion, as a supplement, he wrote another thirty volumes of 『千金翼方』. Mr. Sun integrated his discoveries in the treatments of the aged patients, and his opinions for longevity into the Volumes 『養性』 (Cultivating the Character), 『?穀』(Fasting), 『退居』(Retirement), 『補益』(Supplementation). Thus he laid down the basic foundation for the gerontology of Chinese medicine. 『千金要方』 and 『千金翼方』 by Mr. Sun discuss mainly the prevention of illness for aged patients. As for the function of food therapy, he explains: 'Food can dispel evil elements of the body and settle down its organs. It can further bring pleasure to man's spirit and help the circulation of blood and breath.' He then propose the major method of food therapy: 'For a medical doctor, he should understand the causes of disease, then treat it with food. Only after the food treatment fails, medicine is employed.' He thinks that medicine does work in treatment, but it also creates imbalance in the body, and makes the latter vulnerable to outside harms. Therefore, a good doctor is the one who cures the disease and bring pleasure to the patient with food. He stresses that food therapy is always a priority. Mr. Sun prefers animal's organs in the food therapy for aged. For example, he uses powder of sheep's kidney to treat the lumbago. He suggests the viewpoint of 'Curing man's organs with animal's organs' and 'Strengthening man's organs with animal's organs,' and sets the theoretical foundation of 'Organic Treatment.' Mr. Sun's gerontology and food therapy received further development latter. The prescriptions contained therein had been widely used in 王懷隱's 『太平聖惠方』 and 陳直's 『養老奉親書』, both in the Song Dynasty. Eventually they had become a science of food therapy for aged patients.

• 디지털융복합연구
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• 제18권8호
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• pp.201-215
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• 2020

본 연구는 디지털 헬스기기의 통합적 고령자 기술수용도 모델을 검증하기 위해 『2019년 한국 중·고령자 기술수용도 조사』 자료를 활용하여 분석을 실시하였다. 본 연구는 기존 기술수용요인인 유용성, 편의성, 확장된 기술요인인 효능감, 불안, 촉진 뿐 아니라 연령에 대한 태도와 삶의 만족도와 디지털 헬스기기 이용의도 간 유의미한 영향관계를 구조 방정식을 통해 살펴보았다. 구체적인 연구모형 검증결과는 다음과 같다. 첫째, 디지털 헬스기기에 대한 유용성, 편의성이 높을수록 디지털 헬스기기를 이용할 의도가 높은 것으로 나타났다. 둘째, 자기효능감이 높을수록 디지털헬스기기를 이용하고자 하는 의도는 오히려 낮아지는 것으로 나타났다. 셋째, 디지털 헬스기기에 대한 편의성, 자기효능감과 불안이 높을수록 유용성 또한 증진되는 것으로 나타났다. 마지막으로 자기효능감, 촉진, 연령에 대한 태도 및 삶의 만족은 편의성과 정적으로 관계를 가지는 것으로 나타났다. 본 연구는 기존의 제한적으로 연구되었던 고령자 기술모형을 확대하여 통합적 고령자 기술수용도 모델을 검증하였다는 것에 연구의 의의를 가진다.

• 대한가정학회지
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• 제49권10호
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• pp.57-69
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• 2011

The purpose of the present study was to examine married female immigrants' life style and marriage satisfaction on the perception of preparing their old age. We also investigated how socio-demographic factors influence their Preparation for old age. For the study, -data were collected from 350 questionnaires obtained from female immigrants living in Chungcheongnam-do. Cronbach's ${\alpha}$ tests were conducted for reliability, and regressional analysis was conducted to test our hypotheses. The results of this study shows that there is evidence of relations among the sub-variables. However, we found attitudes to safety and material pursuit are not related to married female immigrants' preparations for their old age. On the other hand, the results indicate that their life style and marriage satisfaction influences their perception of preparing their old age in a positive way. Finally, sociodemographic factors such as gender, age, education, marriage status, occupation and income are shown to affect the women's perception of preparing their old age positively.

• 한국지역사회생활과학회지
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• 제22권4호
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• pp.705-717
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• 2011

This research was based on surveys about differences of perception on retirement among the babe-boomers. Middle-aged men and women in their 40s' and 50s' residing in metropolitan areas centering around Seoul were the main targets for the surveys. Results indicated meaningful differences between men and women in the level of percection and expectation about their retirement. More specifically, men noted physical health, economic sufficiency and work as significant factors for happy retirement. Women, on the other hand, answered economic sufficiency first, and then physical health and relationship with spouse as the important variables for retirement. In addition, men and women portrayed different expectations for difficulties of retirement. Based on the survey results, this research proposed possible national, social, corporate, and individual approaches for secure retirement of the middle-aged baby-boom generation.

• BMB Reports
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• 제52권1호
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• pp.13-23
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• 2019

Aging is accompanied by a time-dependent progressive deterioration of multiple factors of the cellular system. The past several decades have witnessed major leaps in our understanding of the biological mechanisms of aging using dietary, genetic, pharmacological, and physical interventions. Metabolic processes, including nutrient sensing pathways and mitochondrial function, have emerged as prominent regulators of aging. Mitochondria have been considered to play a key role largely due to their production of reactive oxygen species (ROS), resulting in DNA damage that accumulates over time and ultimately causes cellular failure. This theory, known as the mitochondrial free radical theory of aging (MFRTA), was favored by the aging field, but increasing inconsistent evidence has led to criticism and rejection of this idea. However, MFRTA should not be hastily rejected in its entirety because we now understand that ROS is not simply an undesired toxic metabolic byproduct, but also an important signaling molecule that is vital to cellular fitness. Notably, mitochondrial function, a term traditionally referred to bioenergetics and apoptosis, has since expanded considerably. It encompasses numerous other key biological processes, including the following: (i) complex metabolic processes, (ii) intracellular and endocrine signaling/communication, and (iii) immunity/inflammation. Here, we will discuss shortcomings of previous concepts regarding mitochondria in aging and their emerging roles based on recent advances. We will also discuss how the mitochondrial genome integrates with major theories on the evolution of aging.

• BMB Reports
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• 제34권2호
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• pp.144-149
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• 2001

Antioxidant enzymes, scavengers of the reactive oxygen intermediate (ROI), are involved in numerous defense systems in cells. In the present study, we investigated the effects of the hot-water extracts of two medicinally potent mushrooms (Ganoderma lucidum and Phellinus linteus) on the activity and expression of antioxidant enzymes in vitro and in vivo. The mushroom extracts stimulated the catalase activity in a dose-dependent manner in vitro, whereas the other antioxidant enzymes (such as superoxide dismutase (SOD), glutathione peroxidase (GPx)) were unaffected by the extracts. The catalytic activity of catalase in the liver and brain was significantly increased after the oral treatment of the mushroom extracts (2.5 g/kg) to ICR mice for 2 months. Western blot analysis of the liver and brain tissues revealed that the expression level of catalase in the mice, treated with both mushroom extracts, was significantly increased compared to that of the control mice. However, the level of the SOD expression in the mice treated with the natural product extracts was unchanged under the same experimental conditions. Although the mechanisms for the stimulatory effect of the catalase expression by these extracts remains unclear, these results suggest that the ingredients of the Ganoderma lucidum and Phellinus linteus extracts act as an activator of catalase, and regulate the expression of catalase at the translational or transcriptional level.