• Steel and Composite Structures
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• 제31권3호
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• pp.233-242
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• 2019

Early detection of damage bonding state such as insufficient bonding strength and interface partial contact defect for the explosive clad pipe is crucial in order to avoid sudden failure and even catastrophic accidents. A generalized and efficient model of the explosive clad pipe can reveal the relationship between bonding state and vibration characteristics, and provide foundations and priory knowledge for bonding state detection by signal processing technique. In this paper, the slender explosive clad pipe is regarded as two parallel elastic beams continuously joined by an elastic layer, and the elastic layer is capable to describe the non-uniform bonding state. By taking the characteristic beam modal functions as the admissible functions, the Rayleigh-Ritz method is employed to derive the dynamic model which enables one to consider inhomogeneous system and any boundary conditions. Then, the proposed model is validated by both numerical results and experiment. Parametric studies are carried out to investigate the effects of bonding strength and the length of partial contact defect on the natural frequency and forced response of the explosive clad pipe. A potential method for identifying the bonding quality of the explosive clad pipe is also discussed in this paper.

• Korean journal of medical education
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• 제30권4호
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• pp.359-364
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• 2018

Purpose: Learning physiological concepts and their practical applications in the appropriate contexts remains a great challenge for undergraduate medical students. Hence the present study aimed to analyze the learning experience of undergraduate medical students during an active learning process of 'preparation of models' depicting physiological concepts. Methods: A total of 13 groups, involving 55 undergraduate medical students with three to five individuals in each group, were involved in model preparation. A total of 13 models were exhibited by the students. The students shared their learning experiences as responses to an open-ended questionnaire. The students' responses were analyzed and generalized comments were generated. Results: Analysis of the results showed that the act of 'model preparation' improved concept understanding, retention of knowledge, analytical skills, and referral habits. Further, the process of 'model preparation' could satisfy all types of sensory modality learners. Conclusion: This novel active method of learning could be highly significant in students' understanding and learning physiology concepts. This approach could be incorporated in the traditional instructor-centered undergraduate medical curriculum as a way to innovate it.

• 대한건축학회논문집:계획계
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• 제35권7호
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• pp.53-61
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• 2019

Cloud BIM, which incorporates cloud computing technology and BIM technology, is increasingly used in construction. In particular, the recent trend of cloud services in IT field is to provide customized cloud services according to the characteristics of users. These changes are also linked to the cloud BIM, which is emerging in the construction industry. However, cloud BIM researches and commercial technologies that are currently underway do not reflect these trends, and they provide services through generalized management functions in construction projects. In order to solve these problems, a new type of customized cloud BIM service is needed that can provide cloud services by reflecting the characteristics of the project, customization based on the user's work, and providing the knowledge service. Therefore, this study aims to derive the system requirement function that should be preceded for implementing the customized cloud BIM service, and the target project is selected as the medical facility.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권11호
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• pp.4331-4354
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• 2020

Nepal is a sensitive and disaster-prone country where safety and security risk are of high concern for travelers. Digital technologies can play a vital role in addressing safety and security issues in the country. This research work proposes a Digital tourism security system design for addressing the safety and security issues in tourism industry of Nepal. The study uses Design science research methodology to identify artifacts, interactions, information flow and dependencies between them which are then mapped with existing prevalent technology to provide design solutions. Data is obtained from interview of tourist and experts as a primary source and technical documents/draft, software documentations, surveys as secondary source. Generalized information model, Use cases model, Network architecture model, Layered taxonomy model and Digital tourism technology reference model are the outcomes of the study. The work is very important as it talks specifically about implementation and integration of digital technologies in tourism security governance at federal, provincial, municipal and rural level. The research supplements as a knowledge document for design and implementation of digital tourism security system in practice. As there is very less work on digital systems in tourism security of Nepal, this work is a pioneer and first of its kind.

• 호남수학학술지
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• 제43권2호
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• pp.183-197
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• 2021

Recently several authors have extended the Beta function by using its integral representation. However, in many cases no expression of these extended functions in terms of classic special functions is known. In the present paper, we introduce a further extension by defining a family of functions G_r,s : ℝ^*₊ → ℂ, with r, s ∈ ℂ and ℜ(r) > 0. For given r, s, we prove that this function satisfies a second-order linear differential equation with rational coefficients. Solving this ODE, we express G_r,s as a combination of confluent hypergeometric functions. From this we deduce a new integral relation satisfied by Tricomi's function. We then investigate additional specific properties of G_r,1 which take the form of new non trivial integral relations involving exponential and error functions. We discuss the connection between G_r,1 and Stokes' first problem (or Rayleigh problem) in fluid mechanics which consists in determining the flow created by the movement of an infinitely long plate. For $r{\in}{\frac{1}{2}}{\mathbb{N}}^*$, we find additional relations between G_r,1 and Hermite polynomials. In view of these results, we believe the family of extended beta functions G_r,s will find further applications in two directions: (i) for improving our knowledge of confluent hypergeometric functions and Tricomi's function, (ii) and for engineering and physics problems.

• 한국자기공명학회논문지
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• 제26권1호
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• pp.1-9
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• 2022

There are two distinct approaches to improving the quality of protein NMR structures during refinement: all-atom force fields and accumulated knowledge-assisted methods that include Rosetta. Mao et al. reported that, for 40 proteins, Rosetta increased the accuracies of their NMR-determined structures with respect to the X-ray crystal structures (Mao et al., J. Am. Chem. Soc. 136, 1893 (2014)). In this study, we calculated 32 structures of those studied by Mao et al. using all-atom force field and implicit solvent model, and we compared the results with those obtained from Rosetta. For a single protein, using only the experimental NOE-derived distances and backbone torsion angle restraints, 20 of the lowest energy structures were extracted as an ensemble from 100 generated structures. Restrained simulated annealing by molecular dynamics simulation searched conformational spaces with a total time step of 1-ns. The use of GPU-accelerated AMBER code allowed the calculations to be completed in hours using a single GPU computer-even for proteins larger than 20 kDa. Remarkably, statistical analyses indicated that the structures determined in this way showed overall higher accuracies to their X-ray structures compared to those refined by Rosetta (p-value < 0.01). Our data demonstrate the capability of sophisticated atomistic force fields in refining NMR structures, particularly when they are coupled with the latest GPU-based calculations. The straightforwardness of the protocol allows its use to be extended to all NMR structures.

• 창의정보문화연구
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• 제5권2호
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• pp.145-156
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• 2019

본 연구에서는 명명된 실체 인식 기법에 기초한 정보 추출 모듈을 개발하고 평가하였다. 본 논문의 제시된 목적을 위해, 모듈은 사전 지식 없이 임의의 문서에서 우편 주소 정보를 추출하는 문제에 적용하도록 설계되었다. 정보 기술 실무의 관점에서, 우리의 접근방식은 유니그램 기반 키워드 매칭과 비교하여 일반화된 기법인 확률론적 n-gram(바이오그램 또는 트리그램) 방법이라고 말할 수 있다. 모델을 순차적으로 적용하지 않고 문장검출, 토큰화, POS 태그를 재귀적으로 적용하는 것이 우리의 접근법과 자연어 처리에 채택된 전통적인 방법 사이의 주요한 차이점이다. 이 논문에서는 약 2천 개의 문서를 포함한 시험 결과를 제시한다.

• 한국임상수의학회지
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• 제40권3호
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• pp.203-208
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• 2023

A 13-year-old neutered male mixed-breed dog presented with generalized lymphadenopathy and erythematous cutaneous lesions in the ear pinnae. Fine-needle aspiration cytology of the lymph nodes revealed small to intermediate lymphocytes with a "hand mirror" configuration as the predominant cell type. Histopathological analysis of the lymph node showed an infiltrate of CD3-positive small lymphocytes compressing the follicles against the capsule owing to neoplastic cell expansion. Flow cytometric analysis revealed a homogeneous population of CD3+/CD4-/CD5+/CD8-/CD21+/CD34-/CD45- cells in both the peripheral blood and aspirated lymph nodes, which supports the diagnosis of T-zone lymphoma. Laboratory tests revealed lymphocytosis (14,144 cells/µL) in the peripheral blood. However, contrary to expectations, the bone marrow examination revealed no evidence of lymphocytic infiltration. T-zone lymphoma is an indolent lymphoma with a long survival period, and knowledge of its characteristics may affect disease staging and prognosis evaluation. Therefore, peripheral blood count as a sole screening tool for bone marrow metastasis should be used with caution.

• Korean Journal of Mathematics
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• 제32권1호
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• pp.137-162
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• 2024

This paper consists of two significant aims. The first aim of this paper is to establish the criteria for the existence of solutions to nonlinear Volterra-Fredholm (V-F) fractional integral equations on [0, L], where 0 < L < ∞. The fractional integral is described here in the sense of the Katugampola fractional integral of order λ > 0 and with the parameter β > 0. The concepts of the fixed point theorem and the measure of noncompactness are used as the main tools to prove the existence of solutions. The second aim of this paper is to introduce a computational method to obtain approximate numerical solutions to the considered problem. This method is based on the Fibonacci wavelets with collocation technique. Besides, the results of the error analysis and discussions of the accuracy of the solutions are also presented. To the best knowledge of the authors, this is the first computational method for this generalized problem to obtain approximate solutions. Finally, two examples are discussed with the computational tables and convergence graphs to interpret the efficiency and applicability of the presented method.

• 아태비즈니스연구
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• 제14권4호
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• pp.319-330
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• 2023

Purpose - The purpose of this paper is to examine the connectedness between categorical economic policy uncertainty (monetary, fiscal, trade and foreign exchange policy uncertainty) indexes and option-implied volatility index in Korea, Japan and the US. Design/methodology/approach - This paper employs the Diebold-Ylmaz (2012) model based on a VAR and generalized forecast error variance decomposition. This paper also conducts regression analyses to investigate whether the volatility indexes are explained by categorical policy uncertainty indexes. Findings - First, we find the total connectedness is stronger in Korea and Japan relative to the US. Second, monetary, fiscal, and foreign exchange policy uncertainty indexes are connected to each other but trade policy uncertainty index is not. Third, the volatility index in Japan and the US is mainly associated with monetary policy uncertainty while the volatility index in Korea is explained by fiscal policy uncertainty index. Research implications or Originality - To our knowledge, this is the first study to investigate the connectedness among categorical policy uncertainty indexes and the volatility index in Korea, Japan, and the US. The empirical results on the connectedness suggest that transparent policy and communication with the market in one type of policy would reduce the uncertainty in other policies.