• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5287-5291
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• 2014

Background: The cancer survival rate in Korea has substantially increased, necessitating the management of not only patients with cancer but also longer term survivors. Although the divorce rate has drastically increased in Korea, there is not sufficient research regarding the relationship between changes in marital status and quality of life (QOL) in cancer patients and survivors. Thus, we aimed to examine the relationship between marital status and QOL in such cases. Materials and Methods: This study was performed using the Community Health Survey of 2008 administered by the Korea Centers for Disease Control and Prevention (N=169,328). We used t-tests and Chi-square tests to compare demographic variables between men and women, and analysis of variance (ANOVA) to compare QOL scores among comparison groups. We also performed a multilevel analysis on the relationship between QOL and marital status while accounting for provincial differences. Results: Decline of EuroQOL five dimensions (EQ-5D) in single patients with cancer was greater than in any other marital status group, but there was no statistically significant decline in survivors of cancer with regard to marital status. In the general population, the decline of EQ-5D was higher among single people than married people. Using the EuroQOL visual analog scale (EQ-VAS), single people had higher values than those of other marital status among both patients with cancer and survivors of cancer. In the general population, EQ-VAS values were higher for single people compared to married people. Conclusions: There may be a significant relationship between marital status and QOL in cancer patients and survivors. Policy interventions to manage patients with cancer who experience a decline in QOL as well as marital problems should be conducted.

• The Korean Journal of Cytopathology
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• v.5 no.1
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• pp.10-14
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• 1994

The expression of sex steroid hormone receptors by neoplastic cells is an important predictor of response to hormone therapy. Thus, the selection of treatment modality is often based on the identification of receptors in tumor tissue. Various monoclonal antibodies of high specificity are now available for analyzing the estrogen receptor (ER). With these antibodies, biochemical enzyme immunoassay and immunohistochemistry using histologic sections have been used for ER analysis. We used fine needle aspirates from 15 human primary breast carinomas for the analysis of ERs. The semiquantitative receptor values obtained in cytologic specimens were correlated well with those from histologic specimens. The results of ER in fine needle aspirates were concordant with ER in histologic specimens(r=0.94). Only three cases showed a little difference in staining intensity and proportion of positive cells. Our results showed a good correlation between the receptor values determined in cytologic smears and those determined in tissue sections. It is suggested that measurement of the ER in cytologic smears may be a reliable technique which can be performed on aspiration cytologic samples.

• Archives of Pharmacal Research
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• v.23 no.2
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• pp.121-127
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• 2000

Cannabigerol (1, CBG), methyl 4-[(2E)-3,7-dimethyl-2,6-octad ienyl)oxy]-3-methoxybenzoate (2, DTM), 5-fluorouracil (3, FU) as a reference, and cannabidiol (4, CBD) were tested for their growth inhibitory effects against KB(ATCC NO, OCL 17) cell lines using two different assays, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide (MTT) assay and the sulforhod-amine B protein (SRB) assay. These compounds showed inhibitory activity in vitro in the micromolar range against KB cell lines. In general, the antitumor activities of these compounds (1, 2, 3 and 4) were dose-dependent over the micromolar concentration range of 1 to 100 M. The comparison of $IC_{50}$ values of these compounds in tumor cell lines showed that their susceptibility to these compounds decreases in the following order: DTM > CBD > 5-FU > CBG by MTT assay and DTM = CBD > 5-FU > CBG by SRB assay. CBG 1, DTM 2, 5-FU 3, and CBD 4 were tested for their cytotoxic effects on NIH 3T3 fibroblasts using two different assays, the MTT assay and SRB assay. These compounds exhibited potent cytotoxic activities in vitro in the micromolar range against NIH 3T3 fibroblasts. In general, the cytotoxic acivities of these compounds (1, 2, 3 and 4) were dose-dependent over the micromolar concentraion range of 1 to 100 M. The comparison of $CD_{50}$ values of these compounds in NIH 3T3 fibroblasts shows that their susceptibility to these compounds in decreases the following order(:) CBD > 5-FU > DTM > CBG by MTT assay, CBD > 5-FU > CBG > DTM by SRB assay. These results suggest that DTM 2 has the most growth-inhibitory activity against KB cell lines.

• Spatial Information Research
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• v.19 no.1
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• pp.41-50
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• 2011

In Chilgok, industrial complex and agro-industrial complex has facilitated with the population growth rate of 2.79% since 1995. And the city should be apparently required more additional land for agriculture and industrial complex due to the demands of developments. However, many experts has pointed out that utilization of national and public property might be declined recently because the property management office owns too many unnecessary idle lands. So the city is being faced with the necessity of establishing an efficient system for the management of available lands. Therefore, this study evaluated the economic value of available national and public land in Chilgok city. Rental or sale of economic value by separating the target has been also assessed. As a result, each town has totally different characteristics of available lands and the economic values and the numerical change of economic values can measure when merge lots.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.31 no.1
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• pp.163-192
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• 2020

Old maps of Dokdo are records with the physical specificities of a map while also holding historical meanings and evidencial values as ancient writings. Therefore more detail and meaningful descriptions are needed than other general records. However, in comparison to the high interest in these maps, there is a lack of systematic and integrative descriptions. Hence, this study aimed to propose the description elements of the old maps of Dokdo holding evidential values. For this purpose, first, literature reviews and the characteristics of the old maps of Dokdo were analyzed. Next, for determining description elements using institutions that possess old maps of Dokdo, case studies were conducted in 12 domestic and foreign institutions and compared the rules of ISAD(G). The final description elements were suggested by reflecting on the evaluation of five experts in old maps. Fifty description elements in a total of 8 areas - identity areas, context areas, content and structure areas, conditions of access and use areas, allied materials areas, note areas, description control areas, and other areas were proposed.

• The Journal of Engineering Research
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• v.4 no.1
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• pp.109-118
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• 2002

In this research, the cation-exchange-reactions between Na-Montmorillonite and betaine compound, $R_{11}SO_4$, with acid group at the end of alkyl chain were performed under the general condition with dist. water including $CO_2$ and under the different pH-conditions with dist. water without $CO_2$, and their behaviors were observed. As results the exchange reaction under the general condition was perfectly finished after 49 h exchange time, and the basal spacings obtained under the exchange solution and after washing with methanol and drying in high vacuum were 23.6, 17.1 and $15.0\AA$, respectively. The basal spacings obtained under pH-exchange solution after exchange time under different pH-values lied between about 24.7 and $25.6\AA$ independently of the pH-values, and those measured after drying on the air and in high vacuum were about $20.0\AA$ and $13.8~14.4\AA$, respectively.

• Journal of Society of Preventive Korean Medicine
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• v.5 no.1
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• pp.144-150
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• 2001

The cytotoxic activity of Cratalariae sessiliflorae on cultured NIH 3T3 fibroblasts and human oral epithelioid carcinoma cells (KB) were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide (MTT) colorimetric method These fractions of methanol extract of Cratalariae sessiliflorae showed inhibitory effect in vitro in the milligram range against KB cell lines. In general, the antitumor activities of these fractions were does-dependent over the milligram range. The comparison of IC50 values of these fractions in tumor cell lines showed that their susceptibility to these fractions decrease in the following order: Fr. 4> Fr. 6> Fr. 10> Fr. 2> Fr. 11> Fr. 3> Fr. 8> Fr. 7> Fr. 9> Fr. 1> Fr. 5 by the MTT assay. These fractions were tested for their cytotoxic effects on NIH 3T3 fibroblasts using MTT assay. They exhibited potent cytotoxic activities in vitro in the milligram range against NIH 3T3 fibroblasts. In general, the cytotoxic activities of these fractions were does-dependent over the milligram range. The comparison of CD50 values of these fractions in NIH 313 fibroblasts shows that their susceptibility to these fractions in decrease the following order: Fr. 10> Fr. 9> Fr. 2 = Fr. 4> Fr. 8> Fr. 11> Fr. 1 = Fr. 7> Fr. 3> Fr. 5 = Fr. 6 by the MTT assay. These results suggests that fraction 5 has the most growth - inhibitory activity against KB cell lines.

• The Korean Journal of Food And Nutrition
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• v.30 no.4
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• pp.804-812
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• 2017

This study investigated the effects of Goami 2 on the properties of Garaetteok. The moisture, crude protein, crude lipid and crude ash contents of the rice were 16.02, 5.40, 1.87 and 0.77%, respectively. The amylose contents (32.16%) and total dietary fiber contents (9.03%) were the highest in Goami 2. The water binding capacity of Goami 2 (167.84%) was higher than general rice flour. Using a rapid visco analyzer (RVA), the initial pasting temperature of Goami 2 was found to be the highest; also, the peak viscosities of Goami 2 were higher than general rice powder. To assess the effect of Goami 2 on the quality characteristics of Garaetteok, the rice-cake was made by adding various amounts of Goami 2 (0, 10, 20, 30, and 40% w/w) to rice. It was observed that higher the amount of added Goami 2, lower were the grades. In terms of the color values of Goami 2 addition, the L-values of Garaetteok were lower with increasing amount of Goami 2; addition of 40% Goami 2 had the lowest value. The textural properties (hardness) also showed that tteok containing the greater amounts of Goami 2 were considerably harder compared with the control. Sensory preference tests revealed that addition of less Goami 2 had the highest scores for appearance, color and overall acceptability, and the Goami 2 added was lower than control. Therefore, as compared to others cultivars, rice flour proved the most acceptable for the preparation of Garaetteok with cultivar rice.

• The Korean Journal of Food And Nutrition
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• v.30 no.4
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• pp.813-822
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• 2017

To investigate the aroma and quality characteristics of wine bestowed by the degree of ripening of Cheongporang grapes, the general quality composition, color, organic acid, physiological activity, aroma component and sensory evaluation were analyzed. The general characteristics of the wine assessed were pH 3.34~3.50, total acidity 0.46~0.67%, color intensity 0.074~0.116, lightness 98.99~99.74, redness -0.39~0.01, and yellowness was 1.52~3.10. Malolactic fermentation was not relative to the contents of malic acid and lactic acid. The total polyphenol content and antioxidant activity were lowest in C3 wines made with ripe grapes and highest in C4 wines made with mixed grapes. Aroma analysis identified 6 alcohols, 15 esters and 5 miscellaneous compounds. Compounds with higher odor activity value (OAV) were 3-methyl-1-butanol, ethyl butanoate, isopentyl acetate, ethyl hexanoate, ethyl octanoate, ethyl decanoate and octanoic acid. The C4 wine, a mixture of grapes with different degrees of ripening, had the highest ester content and ratio. The lowest values were found in the C3 wine made with ripe grapes. Results of the sensory evaluation related the C4 wine, containing a large amount of ester compounds having high OAV values as the aroma component, as the best and most preferred wine.

• Journal of radiological science and technology
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• v.42 no.5
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• pp.329-334
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• 2019

This study was purpose to quantitative evaluation of noise power spectrum(NPS) and studied the quantitative evaluation and characteristics of modulation transfer function(MTF) by obtain the optimal edge image by using Coil in magnetic resonance imaging(MRI) equipment through Fujita theory using edge method. The MRI equipment was used (Tim AVANTO 1.5T, Siemense healthcare system, Germany) and the head matrix coil were 12channels(elements) receive coil. The NPS results of showed the best value of 0.004 based on the T2 Nyquist frequency of $1.0mm^{-1}$, and the MTF results of showed that the T1 and T2 values were generally better than the T1 CE and T1 CE FC values. The characteristics of this study were to explain the characteristic method of image quality evaluation in general. To present the quantitative evaluation process and results in the evaluation of MRI image characteristics in radiology.