• Food Science of Animal Resources
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• v.33 no.3
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• pp.369-376
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• 2013

Milk is well known to be rich in some nutrients such as protein, calcium, phosphorus, and vitamins. In particular, absorption and bioavailability of calcium receive lots of attention because calcium is very little absorbed until it is changed to the ionized form in the intestine. In this study, concentration of the soluble calcium was determined in the commercial bovine milk products, which were processed by different heat-treatment methods for pasteurization. As for general constituents, lactose, fat, protein, and mineral were almost same in the liquid milk products by different processors. Ultrafiltration of the skimmed milk caused little change in the permeate as for lactose content but both fat and protein decreased. pH values ranges from 6.57-6.62 at room temperature and slightly increase after centrifugation, 10,000 g, 10 min. Rennet-coagulation activity was the lowest in the ultra high temperature (UHT-)milk compared to the low temperature long time (LTLT-) and high temperature short time (HTST-)milk products. Each bovine milk products contains 1056.5-1111.3 mg/kg of Ca. The content of sulfhydryl group was the lowest in raw milk compared to the commercial products tested. For the skimmed milks after ultrafiltration with a membrane (Mw cut-off, 3 Kd), soluble Ca in the raw milk was highest at 450.2 mg/kg, followed by LTLT-milk 336.4-345.1 mg/kg, HTST-milk 305.5-313.3 mg/kg, UHT-milk 370.3-380.2 mg/kg in the decreasing order. After secondary ultrafiltration with a membrane (Mw cut-off, 1 kD), total calcium in raw milk had a highest of 444.2 mg/kg, and those in the market milk products. As follow: UHT-milk, 371.3 to 378.2 mg/kg; LTLT-milk, 333.3 to 342.2 mg/kg; HTST-milk 301.9 to 311.2 mg/kg in a decreasing order.

• The Korean Journal of Mycology
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• v.40 no.4
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• pp.215-223
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• 2012

This study was aimed to find factors responsible for export potential of oyster mushroom through postharvest treatments including high pressure $CO_2$ and anti-moisture pad. Temperature fluctuation during export simulation induced the condensation of excess moisture resulting in the quality loss due to browning and decay. Anti-moisture pad was effective on inhibition of browning occurrence in part. High temperature exposure ($15^{\circ}C$) as retail simulation greatly offset the positive effect of anti-moisture pad. Short term treatment of high pressure $CO_2$ delayed the surface color changes as hunter L, a, and b values. There was no consistent tendency in total sugar and phenolics between treatments. In general, the export potential of small size mush-room (export size) at harvest was higher than large ones (domestic size). The major factors asso-ciated with the quality decrease of oyster mushroom during export were moisture condensation in packages and temperature fluctuation. Further research is required to improve mushroom export procedures.

• Archives of Plastic Surgery
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• v.36 no.2
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• pp.174-182
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• 2009

Purpose: The Mulliken's method is a one of the very excellent technique to correction of the unilateral cleft lip. It could decrease the need of additional operation and second operation by the early simultaneous correction of unilateral cleft lip and nasal deformity, at a time. Numerous procedures were advocated for the correction of nasal deformity, but with general dissatisfaction of the results, it became obvious that no one procedure is the ideal one. The authors have been operating on unilateral cleft lip by Mulliken's method and long term follow - up of postoperative result was evaluated. Methods: The authors have done long term follow - up of result in the 75 cases unilateral cleft lip patient, during 1 ~ 7 years. That was repaired by simultaneous correction of cleft lip and nasal deformity by Mulliken's method at the period from June, 1997 to December, 2007. The patients were unilateral complete cleft lip 39 cases, unilateral incomplete cleft lip 36 cases. In the severe complete cleft lip cases, lip adhesion operation was done before definite operation. The mean age of unilateral cleft lip operation was 3.2 months. Five anthropometric parameters, which were upper lip, cutaneous lip and vermilion mucosa height, nasal tip protrusion, columella length were measured by Sliding Vernier Caliper. The anthropometric analysis was performed preoperative and postoperative at 6 months, 3, 5 and 7 years and the results were com pared with those of age - matched, normal children. T - tests were used to analyze the differences between the measurements. Results: Long - term postoperative results were evaluated by anthropometrically. Most patients showed adequate growth of upper lip height, vermilion mucosa height and columella length. But nasal tip protrusion was relatively short compare with normal value. Incomplete cleft lip group was nearly normal growth results than complete cleft lip group. Conclusion: In conclusion, we could make harmonious Cupid's bow, natural philtrum and lip, appropriate nasal shape by Mulliken's method. But nasal tip protrusion was under the normal values on complete and incomplete group. And incomplete group was more good results than complete group. We have experienced repair of cleft lip by Mulliken's method with 75 cases of unilateral cleft lip patients and conclude that it was very useful and good method.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.2
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• pp.397-402
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• 2008

The purpose of this study is to prepare black Panax ginseng leaf (PGL) and evaluate its antioxidative effect. In order to make black PGL, the raw PGL was successiely steamed at $95^{\circ}C$ for 3 hr nine times. The antioxidant activities of total saponins (Sa) from PGL and black PGL against peroxyl radicals and peroxynitrites were determined by the total oxy-radical scavenging capacity (TOSC) assay. Specific TOSC values for black PGL-Sa against peroxyl radicals and peroxynitrites were 2.3-fold and 2.1-fold of PGL-Sa, respectively, and 2.2-fold and 5.2-fold of glutathione, a positive control antioxidant, respectively. The black PGL-Sa exhibited stronger antioxidative effect than PGL-Sa. The main ginsenosides of black PGL were $Rg_3,\;Rk_1\;and\;Rg_5$. Among the saponins in black PGL, the amount of ginsenoside $Rg_3$ was examined by HPLC. 22.12 mg of ginsenoside $Rg_3$ was obtained from 1g of dried black PGL.

• Journal of the Korean Wood Science and Technology
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• v.35 no.6
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• pp.23-30
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• 2007

Round piles of Korean larch were excavated from the foundation of ex-Chosunchongdokbu (ex-Chosun Governer-General Building), which was constructed in 1916 and dismantled later in 1996. By the record (Huh, 1996), the Korean larch logs were logged from the Yalu river area near Mt. Baekdu in North Korea. At present, however, Korean larch is not so popular in South Korea. The latewood ratio profiles and strength properties (longitudinal compression, shear, longitudinal tensile, and bending) were obtained. The ratio of latewood from pith to bark increased up to 25 years, and then it showed constant tendency at 40% with some variances. From the microscopic observation, however, the latewood ratio decreased from the heartwood to the sapwood. Compression strength was greater and bending strength was a little lower than the previous reports (references 13~15), which might be attributed to the strength reduction of old structural members by aging or damage in the compression specimens than the bending ones. The flat-grained specimens for the shear and tension test showed higher coefficient of variation (COV) than the edge-grained ones. For the better comparison of results, in case of shear and tensile strength tests, the strength values of the edge-grained specimens were thought to be adopted rather than those of flat-grained ones.

• Water for future
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• v.29 no.2
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• pp.249-260
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• 1996

There have been easily found a number of examples that misleading or unreasonable measuring data set of physical variables are often produced in the field and the laboratory. The primary reason is that the specific requirements of civil engineers are initially disregarded in designing the experimental apparatus. It results from a lack of mutual understanding and co-operating between the user group and the maker. Therefore, their fundamental knowledge and apprehension become indispensible in order to obtain measuring data with high confidence and good quality In this study it is shortly explained the basic structure and the operation system of the experimental equipments commonly used at the present. A simple measuring set is developed which is quite easy for a general civil engineer to design and operate without any other specialty of mostly electricity electronics. Based upon this requirement, one of data logger named PPDL8 is newly designed by making use of the parallel port in the personal computer, consisting of multi-channels able to measure 8 different point values simultaneously. It can also use many valuable sub-programs existing in PC because the user makes his own programs necessary for measurement, by himself. Of all things, it has a great advantage to increase the applicability of field measurements much larger when adopting the notebook computer to operate with small battery only. In addition this study gives, in fact, the excellent agreements of in-situ field variables by showing their measuring results of temperature, distance and turbidity.

• Journal of Korea Water Resources Association
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• v.49 no.8
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• pp.685-692
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• 2016

This study aimed to develop the indicator-based approach to assess water use vulnerability in watersheds and applied to the unit watershed within the Han River watershed. Vulnerability indices were comprised of three sub-components (exposure, sensitivity, adaptive capacity) with respect to water use. The indicators were made up of 16 water use indicators. Then we estimated vulnerability indices using the Technique for Order of Preference by Similarity to Ideal Solution approach (TOPSIS). We collected environmental and socio-economic data from national statistics database, and used them for simulated results by the Soil and Water Assessment Tool (SWAT) model. For estimating the weighted values for each indicator, expert surveys for subjective weight and data-based Shannon's entropy method for objective weight were utilized. With comparing the vulnerability ranks and analyzing rank correlation between two methods, we evaluated the vulnerabilities for the Han River watershed. For water use, vulnerable watersheds showed high water use and the water leakage ratio. The indices from both weighting methods showed similar spatial distribution in general. Such results suggests that the approach to consider different weighting methods would be important for reliably assessing the water use vulnerability in watersheds.

• Journal of Korea Water Resources Association
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• v.47 no.3
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• pp.285-295
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• 2014

We applied the ISPSO-GLUE method, which integrates the Isolated-Speciation-based Particle Swarm Optimization (ISPSO) with the Generalized Likelihood Uncertainty Estimation (GLUE) method, to the uncertainty analysis of the Topography Model (TOPMODEL) and compared its performance with that of the GLUE method. When we performed the same number of model runs for the both methods, we were able to identify the point where the performance of ISPSO-GLUE exceeded that of GLUE, after which ISPSOGLUE kept improving its performance steadily while GLUE did not. When we compared the 95% uncertainty bounds of the two methods, their general shapes and trends were very similar, but those of ISPSO-GLUE enclosed about 5.4 times more observed values than those of GLUE did. What it means is that ISPSOGLUE requires much less number of parameter samples to generate better performing uncertainty bounds. When compared to ISPSO-GLUE, GLUE overestimated uncertainty in the recession limb following the maximum peak streamflow. For this recession period, GLUE requires to find more behavioral models to reduce the uncertainty. ISPSO-GLUE can be a promising alternative to GLUE because the uncertainty bounds of the method were quantitatively superior to those of GLUE and, especially, computationally expensive hydrologic models are expected to greatly take advantage of the feature.

• Korean Journal of Logic
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• v.16 no.3
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• pp.347-380
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• 2013

In this paper I will try to show how Wittgenstein criticized Frege's theory of meaning. Frege's theory of meaning can be compressed as sense-reference theory. Frege distinguishes between sense and reference on all the linguistic expressions. In particular, he regards that a sentence has sense and reference. This distinction was raised from, so to speak, the problem of identity sentences. Wittgenstein's "fundamental thought" of Tractatus Logico-Philosophicus is the key of his direct criticism of Frege's sense-reference theory. That is, it is an attack on Frege's thought that the reference of a sentence is a truth value and truth values are "objects themselves" (in Frege's meaning). According to Wittgenstein, such an object does not exist and according to his picture theory, the function of a name and that of a proposition are fundamentally different. By the way, Frege can reply justly to this criticism that it is insufficient. In short, Frege's 'sense' and 'reference' etc, are the technical terms. Hence Wittgenstein's decisive criticism of Frege's theory consists in accusing his theory of logical flaws. There is an another route to the sense and reference of a sentence which Frege introduces. In discourses of judgement stroke and content stroke in his Begriffsshrift and in those of horizontal stroke since his "Function and Concept", Frege deals with the sense and reference of a sentence. Wittgenstein criticize that the sense of a complex sentence such as ~p would by no means be determined by Frege's determination.

• Journal of Pharmaceutical Investigation
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• v.37 no.5
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• pp.315-321
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• 2007

The purpose of the present study was to evaluate the bioequivalence of two lercanidipine hydrochloride tablets, Zanidip tablet (LG Life Sciences Ltd., Korea, reference drug) and Samchundang Lercanidipine tablet 10 mg (Sam Chun Dang Pharm. Co. Ltd., Korea, test drug), according to the guidelines of Korea Food and Drug Administration (KFDA). After adding an internal standard (amlodipine maleate) to human serum, serum samples were extracted using hexan-isoamyl alcohol (100:1, v/v). Compounds were analyzed by liquid chromatography/tandem mass spectrometry. This method showed linear response over the concentration range of 0.05-20 ng/mL with correlation coefficient of 0.9999. The lower limit of quantitation using 0.5 mL of serum was 0.05 ng/mL which was sensitive enough for pharmacokinetic studies. Thirty healthy male Korean volunteers received each medicine at the lercanidipine hydrochloride dose of 20 mg in a $2\;{\times}\;2$ crossover study. There was a one-week washout period between the doses. Serum concentrations of lercanidipine were monitored by an LC/MS/MS fer over a period of 24 hr after the administration. $AUC_t$ (the area under the serum concentration-time curve from time 0 to 24 hr) was calculated by the linear trapezoidal rule method. $C_{max}$ (the maximum serum drug concentration) and $T_{max}$ (the time to reach $C_{max}$) were compiled from the serum concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters, indicating that the crossover design was properly performed. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for Samchundang Lercanidipine/Zanidip were log 0.9505-log 1.2258 and log 0.9987-log 1.2013, respectively. These values were within the acceptable bioequivalence intervals of log 0.80-log 1.25. Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating Samchundang Lercanidipine tablet 10 mg and Zanidip tablet are bioequivalent.