• Journal of Pharmaceutical Investigation
• /
• 제34권5호
• /
• pp.427-433
• /
• 2004

With the Sunshine policy, exchange of materials and cultures inter Koreas has been broadened and expectancy of reunification is getting higher. Especially, medical supplies and medicines are one of the biggest parts in the exchange goods. So, preparing an unified official drug standard preparing new medical administration system is required. We compared the Korean pharmacopoeia with North Korean Pharmacopoeia. Two pharmacopoeias have been developed in different direction and have many differences in the nomenclature and format. In this study, we compared general notices, general rules for preparations and crude drugs, monographs, general tests, processes and apparatus.

• Monthly Notices of the Royal Astronomical Society
• /
• 제513권4호
• /
• pp.5606-5610
• /
• 2022

Mass-loss of massive helium stars is not well understood even though it plays an essential role in determining their remnant neutron-star or black hole masses as well as ejecta mass of Type Ibc supernovae (SNe Ibc). Radio emission from SNe Ibc is strongly affected by circumstellar matter properties formed by mass-loss of their massive helium star progenitors. In this study, we estimate the rise time and peak luminosity distributions of SNe Ibc in radio based on a few massive helium star mass-loss prescriptions and compare them with the observed distribution to constrain the uncertain massive helium star mass-loss rates. We find that massive helium stars in the luminosity range expected for ordinary SNe Ibc progenitors (4.6≲log L/L_⊙≲5.2) should generally have large mass-loss rates (≳10^-6M_⊙yr^-1) in order to account for the observed rise time and peak luminosity distribution. Therefore, mass-loss prescriptions that predict significantly low mass-loss rates for helium stars in this luminosity range is inconsistent with the SN radio observations. It is also possible that massive helium stars shortly before their explosion generally undergo mass-loss enhancement in a different way from the standard radiation-driven wind mechanism.

• Monthly Notices of the Royal Astronomical Society
• /
• 제491권2호
• /
• pp.2268-2279
• /
• 2020

It is known observationally that the major axes of galaxy clusters and their brightest cluster galaxies are roughly aligned with each other. To understand the origin of the alignment, we identify 40 cluster-sized dark matter (DM) haloes with masses higher than 5 × 10¹³ M_⊙ and their central galaxies (CGs) at z ≈ 0 in the Horizon-AGN cosmological hydrodynamical simulation. We trace the progenitors at 50 different epochs between 0 < z < 5. We then fit their shapes and orientations with a triaxial ellipsoid model. While the orientations of both DM haloes and CGs change significantly due to repeated mergers and mass accretions, their relative orientations are well aligned at each epoch even at high redshifts, z > 1. The alignment becomes tighter with cosmic time; the major axes of the CGs and their host DM haloes at present are aligned on average within ~30° in the 3D space and ~20° in the projected plane. The orientations of the major axes of DM haloes on average follow one of the eigenvectors of the surrounding tidal field that corresponds to the slowest collapsing (or even stretching) mode, and the alignment with the tidal field also becomes tighter. This implies that the orientations of CGs and DM haloes at the present epoch are largely imprinted in the primordial density field of the universe, whereas strong dynamical interactions such as mergers are important to explain their mutual alignment at each epoch.

• Monthly Notices of the Royal Astronomical Society
• /
• 제488권1호
• /
• pp.1427-1445
• /
• 2019

H₂O (22 GHz) and SiO masers (43, 86, 129 GHz) in the bipolar proto-planetary nebula OH 231.8+4.2 were simultaneously monitored using the 21-m antennas of the Korean VLBI Network in 2009-2015. Both species exhibit periodic flux variations that correlate with the central star's optical light curve, with a phase delay of up to 0.15 for the maser flux variations with respect to the optical light curve. The flux densities of SiO v = 2, J = 1→0 and H₂O masers decrease with time, implying that they may disappear in 10-20 yr. However, there seems to have been a transient episode of intense H₂O maser emission around 2010. We also found a systematic behaviour in the velocity profiles of these masers. The velocities of the H₂O maser components appear to be remarkably constant, suggesting ballistic motion for the bipolar outflow in this nebula. On the other hand, those of the SiO maser clumps show a systematic radial acceleration of the individual clumps, converging to the outflow velocity of the H₂O maser clumps. Measuring the full widths at zero power of the detected lines, we estimated the expansion velocities of the compact bipolar outflow traced by H₂O maser and SiO thermal line, and discussed the possibility of the expanding SiO maser region in the equatorial direction. All of our analyses support that the central host star of OH231.8 is close to the tip of the AGB phase and that the mass-loss rate recently started to decrease because of incipient post-AGB evolution.

• Monthly Notices of the Royal Astronomical Society
• /
• 제491권3호
• /
• pp.4045-4056
• /
• 2020

We examine whether galaxy environments directly affect triggering nuclear activity in Sloan Digital Sky Survey (SDSS) local spiral galaxies using a volume-limited sample with the r-band absolute magnitude M_r < -19.0 and 0.02 <z< 0.055 selected from the SDSS Data Release 7. To avoid incompleteness of the central velocity dispersion σ of the volume-limited sample and to fix the black hole mass affecting AGN activity, we limit the sample to a narrow σ range of 130 km s^-1 <σ< 200 km s^-1. We define a variety of environments as a combination of neighbour interactions and local density on a galaxy. After the central star formation rate (which is closely related to AGN activity level) is additionally restricted, the direct impact of the environment is unveiled. In the outskirts of rich clusters, red spiral galaxies show a significant excess of the AGN fraction despite the lack of central gas. We argue that they have been pre-processed before entering the rich clusters, and due to mergers or strong encounters in the in-fall region, their remaining gases efficiently lose angular momentum. We investigate an environment in which many star-forming galaxies coexist with a few starburst-AGN composite hosts having the highest [O_III] luminosity. We claim that they are a gas-rich merger product in groups or are group galaxies in-falling into clusters, indicating that many AGN signatures may be obscured following the merger events.

• 한국전자거래학회지
• /
• 제3권2호
• /
• pp.37-55
• /
• 1998

This study describes the works on development of a scenario-based WBT system of electronic commerce to introduce and activate electronic commerce in our society because it is mostly required to correctly understand electronic commerce and timely educate its users and technicians for entering into global electronic commerce that binds every commercial area regardless of the borders and nationalities. This system, WBT(Web - Based Training of Electronic commerce), consists of two parts. The one part provides a general concept of EC. This is developed to meet the needs of beginner for EC. The other is a simulator for cyber shopping mall. It is designed for teaching how to shop at cyber shopping mall based on various scenarios. In addition, we can simulate ourselves for EDI, which enables trading partners to conduct routine business transaction, such as purchase orders, invoices and shopping notices with it. Our commitment to the development of this application is consistent with the objectives of being easy to learn electronic commerce and its applications in real world.

• Journal of Korean Biological Nursing Science
• /
• 제17권4호
• /
• pp.315-323
• /
• 2015

Purpose: This study compared the effect of music and noise blocking on the vital signs, postoperative pain, analgesic use, length of stay in the Post Anesthesia Care Unit (PACU) and satisfaction after a laparoscopic colectomy. Methods: This randomized controlled trial was performed in a 555-bed National Cancer Center, from February 13 through May 31, 2012. Subjects consisted of 69 patients who underwent a laparoscopic colectomy under general anesthesia, and were recruited by informed notices. The inclusion criteria were patients between the ages of 35-75, with an American Society Anesthesiologist physical classification I or II. The subjects were randomly allocated to three groups; music therapy group (MTG), noise blocking group (NBG) and control group (CG). Collected data were analyzed using Repeated measures ANOVA, one-way ANOVA and Kruskal-Wallis test through IBM SPSS (Version 19.0). Results: There were no significant differences in vital signs among the three groups. Postoperative pain in MTG (p<.05) and NBG (p<.05) was significantly decreased compared to CG. The amount of analgesics (p=.030) and length of stay at PACU (p=.021) in MTG was significantly decreased compared to NBG or CG; satisfaction in MTG and NBG was significantly higher compared to CG. Conclusion: Music seems to reduce postoperative pain, the amount of analgesics, and the length of stay at PACU. Therefore, music therapy is considered to be included in nursing intervention for postoperative patients at PACU.

• 대한의용생체공학회:의공학회지
• /
• 제19권6호
• /
• pp.623-629
• /
• 1998

일반전화기로 통화가 어려운 난청인에게 충분한 수신음량을 공급하기 위해서는 큰 증폭이 필요한데 큰 증폭은 하울링(howling)을 발생시킨다. 본 연구에서는 소리를 크게 증폭하면서 하울링을 억제하는 새로운 방법을 제안하고 이를 적용한 보청전화기를 개발하여 평가하였다. 통화수신 음성은 3개의 밴드로 나뉘어져 각각 독립적으로 증폭되어 난청인의 청력에 알맞게 적합(fitting)된다. 수신음성의 주파수는 카운터에 의하여 시간영역에서 모니터링되는데 카운터부는 비교기를 이용하여 수신 정현파를 구형파로 변환시키고 시간영역에서 구형파 수를 계수함으로써 주파수를 분석하여 하울링이 발행하는가를 판단한다. 전화기는 송수화기 구조가 결정되어 있고 송수신 주파수 범위가 제한되어 있으므로 하울링 또한 일정주파수 범위내 발생하게 된다. 계수기에 의해 하울링이 검출되면 중앙제어부는 해당대역의 증폭도를 빠르게 낮춤으로써 하울링을 억제시킨다. 시험결과 개발전화기는 하울링 없이 40dB 이상 증폭할 수 있으며 중고도 난청인의 어음인지력이 1음절어의 경우는 20%에서 60.8%로, 2음절어의 경우는 28.9%에서 78%로 향상되는 탁월한 개선 효과를 보였다.

• 기술혁신연구
• /
• 제21권2호
• /
• pp.169-197
• /
• 2013

다수의 이론적, 실증적 연구에도 불구하고 지식재산권 제도와 기업의 기술혁신 및 경영성과간의 일반적 인과관계는 명확하지 않다. 본 연구는 산업별 기업 경영성과의 핵심 요인이 상이하다는 점에 주목한다. 이를 바탕으로 (1)지식재산권 강화${\rightarrow}$연구개발의 투입/산출 증가${\rightarrow}$매출증가로 이어지는 기본 성과창출경로가 작용하는 제약 산업, (2)지식재산권 강화와 연구개발 투입/산출간 관계가 약한 반도체산업, (3)연구개발과 매출 간 관계가 약한 조선 산업까지 세 산업을 대상으로 지식재산권 제도가 기술혁신과 경영성과에 미치는 영향을 분석했다. 한국의 특허제도가 선진국 수준에 이른 TRIPs 이후 15년간의 대기업 패널 데이터를 사용했으며, 고정효과모형을 차분 GMM으로 추정해 동태적 인과관계를 분석했다. 결과적으로, 지식재산권 강화가 제약 산업에서는 연구개발의 투입/산출 및 경영성과를 모두 증가시켰지만, 반도체-조선 산업에서는 영향을 미치지 못하는 것으로 나타났다. 즉, 지식재산권 강화를 위한 제도 구축과 정책은 산업별로 맞춤화될 필요가 있으며, 획일적인 강화/약화는 특정 산업의 경영성과 제고에 유의미한 영향을 미치지 못한다.