• 제목/요약/키워드: general component measurement

검색결과 55건 처리시간 0.026초

웨이브렛 변환을 이용한 스트레스 심전도 분석 알고리즘의 개발 (Development of a Stress ECG Analysis Algorithm Using Wavelet Transform)

  • 이경중;박광리
    • 대한의용생체공학회:의공학회지
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    • 제19권3호
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    • pp.269-278
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    • 1998
  • 본 논문에서는 스트레스 심전도를 분석함에 있어서 가장 중요한 파라미터인 ST 세그먼트를 측정하기 위해서 웨이브렛 변환을 이용하여 Wavelet Adaptive Filter(WAF)와 QRS콤플렉스 검출 알고리즘을 설계하였다. WAF는 웨이브렛 변환부와 적응필터부로 구성되어 있으며, 웨이브렛 변환부에서는 웨이브렛 함수를 이용하여 입력되는 심전도 신호를 저주파 대역과 고주파 대역으로 각각 j=-7레벨까지 분할하고, 적응필터부에서는 웨이브렛 변환에 의해 분할된 신호중 j=-7레벨의 저주파 대역 신호를 주입력으로 사용하여 필터링 한다. QRS 콤플레스는 합산신호를 구성한 후 문턱치를 RR간격에 변화에 따라 변화시키면서 검출하였으며, 합산신호는 웨이브렛 변환에 의해 QRS 콤플렉스의 주파수 성분이 포함되어 있는 고주파 대역의 신호를 더하여 구성하였다. WAF는 표준 필터와 일반적인 적응필터와 성능을 비교하였으며, 잡음제거 특성과 신호왜곡도 측면에서 비교필터에 비해 우수한 성능을 보였다. QRS 콤플렉스 검출성능을 평가하기 위해서 MIT/BIH데이터베이스를 이용하여 기존의 QRS 검출 알고리즘들의 검출 방법과 비교하였으며, 웨이브렛에 의한 합산신호를 이용할 경우에 99..67%로써 더 좋은 검출성능을 보였다. 또한 측정된 ST세그먼트의 정확도를 비교.평가를 위하여 European ST-T 데이터베이스와 실제 임상데이터를 이용하였으며 심박수의 변화에 따라 적응적으로 ST세그먼트를 측정할 수 있었다.

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건조방법에 따른 아로니아의 품질특성 (Quality characteristics of Aronia melanocarpa by different drying method)

  • 이슬;김종국
    • 한국식품저장유통학회지
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    • 제22권1호
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    • pp.56-62
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    • 2015
  • 아로니아의 활용성 제고를 위하여 건조방법에 따른 품질특성을 비교한 결과, 건조과정 중 중량변화율은 진공동결건조가 81.6%로 가장 많은 중량감소를 나타내었고, 수분함량은 진공동결건조에서 가장 많은 수분이 감소하였으며, 건조 후 최종 수분함량은 진공동결건조에서 0.99%로 가장 낮은 함량을 나타내었다. 색도 측정결과, $L^*$값은 건조방법에 따른 큰 차이를 나타내지 않았으며, $a^*$값과 $b^*$값은 진공동결건조와 냉풍건조에서 증가하였고, 열풍건조에서는 감소하였다. 경도는 열풍건조에서는 건조 36시간 이후 급격하게 증가하였고, 냉풍건조는 서서히 증가하다가 132시간 이후 급격하게 증가하는 모습을 보였다. 건조방법에 따른 품질특성으로 건조수율은 냉풍건조가 24.20%로 가장 높았으며, 열풍건조 20.40%, 진공동결건조 19.41% 순으로 나타났다. 일반성분은 생과에서 수분이 61.76%로 가장 높게 나타났으며, 조회분은 열풍건조에서 가장 높게 나타났고, 가용성무질소물, 조단백, 조지방은 진공동결건조에서 가장 높은 함량을 나타내었다. 건조방법에 따른 아로니아의 pH는 3.84~3.92로 큰 차이가 없었으며, 당도는 동결건조($6.57^{\circ}Brix$) > 열풍건조($5.37^{\circ}Brix$) > 냉풍건조($4.40^{\circ}Brix$) > 생과($1.07^{\circ}Brix$) 순으로 나타났다. 무기질 함량은 진공동결건조에서 가장 높았으며, 주요 무기질은 K, Ca, Mg, Na인 것으로 나타났다. 아로니아에 함유된 당은 fructose, glucose 두 종류인 것으로 나타났으며, 진공동결건조가 20.59 g/100 g으로 가장 높은 함량을 가진 것으로 나타났다.

Sialic Acid를 지표성분으로 하는 유청가수분해단백분말의 기능성식품 개발연구 - I. 효소분리로 7% Siailc Acid가 표준적으로 함유된 유청가수분해단백분말(7%)의 랫드를 이용한 90일 반복경구투여 독성시험 평가 연구 - (Development and Research into Functional Foods from Hydrolyzed Whey Protein Powder with Sialic Acid as Its Index Component - I. Repeated 90-day Oral Administration Toxicity Test using Rats Administered Hydrolyzed Whey Protein Powder containing Normal Concentration of Sialic Acid (7%) with Enzyme Separation Method -)

  • 노혜지;조향현;김희경
    • Journal of Dairy Science and Biotechnology
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    • 제34권2호
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    • pp.99-116
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    • 2016
  • 본 시험은 sialic acid가 7%를 함유하도록 제조한 유청가수분해단백분말제제(whey protein of hydrolysis)의 기능성 식품원료로 개발을 위한 동물안전성을 평가함에 연구목표를 두었다. GMP를 원료로 제조한 시험물질은 sialic acid 7%(v/v)와 원료인 GMP 가수분해 단백질이 93%로 구성되어 있었다(시험명: 7%-GNANA). 시험물질의 독성 유무는 한국식품의약안전청(KFDA, 2014)과 OECD(2008)의 의약품 등의 독성시험 기준에 따라 실시하였다. 평가방법으로서, 시험물질의 투여용량을 0, 1,250, 2,500 및 5,000 mg/kg/day로 하여 SPF Sprague-Dawley 계열 암수 랫드에 90일 동안 반복경구투여하였을 때 나타나는 독성 여부를 평가하였다. 평가항목으로서는 사망률, 일반증상관찰, 체중 변화, 사료 섭취량 측정, 안검사, 요검사, 혈액학적 및 혈액생화학적 검사, 부검 시 장기의 중량측정, 부검 시 육안적 검사 및 조직병리학적 검사 등을 평가하였다. 90일 반복경구투여 실험결과로서, 시험물질투여 및 관찰기간 동안 사망동물은 발생하지 않았다. 또한 일반증상, 체중 변화, 사료섭취량, 안과학적 검사, 요검사 그리고 혈액학적 및 혈액이화학적 이상 및 혈액응고검사에서 대조군 대비 특이한 변화는 관찰되지 않았다(p<0.05). 부검 및 병리조직학적 평가 결과, 암수 모두에서 시험물질-유래 중요한 변화 없이 시험물질-유래 경미한 변화(non-adverse effect)만인 5,000 mg/kg/day에서 확인되었다. Weight-based classification(독성 강도에 따른 분류)을 적용한 최종 독성평가 결과, 수컷의 경우 NOEL(No Observed Effect Level)은 5,000 mg/kg/day 그리고 암컷의 경우는 NOAEL(No Observed Adverse Effect Level)은 5,000 mg/kg/day로 최종 확인되었다. 따라서, 암수 모두에서 시험물질의 NOAEL은 투여최대용량인 5,000 mg/kg/day로 확인되었다. 결론적으로, GMP를 원료로 하여 제조한 7%-GNANA(유청가수분해단백분말)는 투여가능 최대용량에서도 독성이 없는 안전한 천연물이라는 것을 확인하였고, 의약품이나 기능성 식품으로서의 개발 가능성을 확인하였다.

학령기 입원아동의 병원관련 공포에 관한 탐색연구 (Identification and Measurement of Hospital-Related Fears in Hospitalized School-Aged Children)

  • 문영임
    • 대한간호학회지
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    • 제25권1호
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    • pp.61-79
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    • 1995
  • When children are admitted to hospital, they have to adapt to new and unfamiliar stimuli. Children may respond with fear to stimuli such as pain or unfamiliar experiences. One goal of nursing is to help hospitalized children to adapt effectively to their hospital experience. Accordingly, nurses need to assess childrens' fears of their hospital experience to contribute to the planning of care to alleviate these fears. The problem addressed by this study was to identify and measure hospital-related fears(hereafter called HRF) in hospitalized school-aged children. The study was conceptualized with Roy's model. A descriptive qualitative approach was used first, followed by a quantitative approach. This study was conducted from November 30, 1989 to January 12, 1991. The sample consisted of 395 hospitalized school-aged children selected through an allocated sampling technique in nine general hospitals. The HRF questionnaire (three point likert scale ) was developed by a delphi technique. The data were analyzed by an SAS program. Factor analysis was used for the examination of component factors. Differences in the HRF related to demographic variables were examined by t-test, analysis of variance and the Scheffe test. The crude scores of the HRF scale were transformed into T- scores to calculate the standard scores. The results included the following : 1. Forty-four items were derived from 188 statements identifying the childrens' hospital-re-lated fears. These items clustered into 14 factors, fear of injections, operations, bodily harm others' pain, medical rounds, physical examinations, medical staff, disease process, blood and X-rays, drugs and cockroaches, tests, harsh discipline from parents or staff, being absent from school, and separation from family. The 14 factors was classified into four categories,'pain','the unfamiliar','the un-known' and 'separation'. 2. The reliability of the HRF instruments was .92(Cronbach's alpha). In the factor analysis, Cronbach's alpha coefficients for the 14 factors ranged from .84 to .86 and Cronbach's alpha coefficients for the four categories ranged from .70 to .84. Pearson correlation coefficient scores for relationships among the 14 factors ranged from ,11 to .50, and among the four categories, from ,44 to ,63, indicating their relative independence. 3. The total group HRF score ranged from 45 to 130 in a possible range of H to 132, with a mean of 74.51. The fears identified by the children were, in order, injections, harsh discipline by parents or staff, bodily harm, operations, medical staff, disease process, and medical rounds ; the least feared was others' pain. The fear item with the highest mean score was surgery and the lowest was examination by a doctor. HRF scores were higher for girls than for boys, and for grade 1 students than for grade 6 students. HRF scores were lower for children whose fathers were over 40 than for those whose fathers were in the 30 to 39 age group, and whose mothers were over 35 than for those whose mothers were in the 20 to 34 age group. HRF scores were lower when the mother rather than any other person stayed with the child. The expressed fear of pain, the unfamiliar, the un-known and of separation directs nurses' concern to the threat felt by hospitalized children to their concept of self. This study contributes to the assessment of fears of hospitalized children and of stimuli impinging on those fears. Accordingly, nursing practice will be directed to the alleviation of pain, pre-admission orientation to the hospital setting and routines, initiation of information about procedures and experiences and arrangments for mothers to stay with their children. Recommendations were made for further research in different settings and for development and testing of the instrument.

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사용자환경의 메타포가 스마트폰 애플리케이션 사용의도에 미치는 영향 (The Effects of Metaphors in the Interface of Smartphone Applications on Users' Intention to Use)

  • 정원진;홍석기
    • Asia pacific journal of information systems
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    • 제24권3호
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    • pp.255-279
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    • 2014
  • It is not too much to say that smartphones have become an essential part of our lives due to their versatility. Nevertheless, they still have less overall capabilities than their desktop counterparts. Specifically, they have small screens and low resolutions, which make their applications difficult to have a usable interface. To account for these limitations, the interface of smartphone applications should be designed carefully and properly. Good interface design to any application is critical. However, a comprehensive information systems (IS) literature review found that there has been little research on the user interface design of smartphone applications. More specifically, there has been little empirical evidence and understanding about how metaphors, an imaginative way of describing objects and concepts, in the user interface of smartphone applications affect users' intention to use the applications. Thereby, the research goals of this study are to examine 1) the effects of the metaphors in the user interface of smartphone applications on the interaction between users and applications and 2) the effects of mediating variables including the interaction between users and applications, users' beliefs and attitudes, on users' intention to use the applications. A survey was conducted to collect data. University students and practitioners participated in the survey. A 24-item questionnaire was developed on a 5-point Likert-type scale. The measurement items were mostly adapted from the previous studies in the IS literature and modified to fit the context of this study. First, a principal component factor analysis was performed to explore the inter-relationships among a set of variables. The analysis showed that most of the items loaded quite strongly on the six components. The analysis also revealed the six components with eigenvalues exceeding 1, explaining a total of 70.7 per cent of the variance. The reliabilities of the items were also checked. Most Cronbach alpha values were above 0.8, so the scales were considered reliable. In sum, the results of the analysis support the decision to retain the six factors for further investigation. Next, the structural model was analyzed with AMOS structural equation modeling. The values of GFI, AGFI, NFI, TLI, CFI, and RMSEA were checked. The values showed that the research model considerably have a good fit in general. Next, the convergent and discriminant validities of all constructs were examined. The values for the standardized regression weights and critical ration (CR) indicated sufficient convergent validity for all constructs. In addition, the square root of the average variance extracted (AVE) of each construct was compared with its correlations with all other constructs. The results supported discriminant validity for all constructs. In sum, the results of analysis demonstrated adequate convergent and discriminant validities for all constructs. Finally, path coefficients between the variables were examined. Methphor was found to have an impact on interaction (${\beta}$ = .457, p = .000). There were also significant effects of the interaction on perceived usefulness (${\beta}$ = .273, p = .000) and ease of use (${\beta}$ = .405, p = .000). User attitude was significantly influenced by these two beliefs, perceived usefulness (${\beta}$ = .386, p = .000) and ease of use (${\beta}$ = .347, p = .000) respectively. Further, the results of analysis found that users' intention to use smartphone applications was significantly influenced by user attitude (${\beta}$ = .567, p = .000). Based upon the analyses, all hypotheses were supported. This study found that the metaphors used in the interface of smartphone applications affect not only the interaction between users and applications, but also users' intention to use the applications through the mediating variables, perceived usefulness and ease of use. These findings imply that if the metaphors used in the user interface of application are easy enough to understand for smartphone users, then the application can be perceived useful and easy to use, which in turn make users to have an intention to use the application. In conclusion, this study contributed not only to validate and extend Technology Acceptance Model (TAM) partially, but also to develop the construct of metaphor in smartphone settings. However, since a single empirical study cannot be enough to validate the findings, some limitations should be considered.