• 성인간호학회지
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• 제28권4호
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• pp.482-490
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• 2016

Purpose: The purpose of the study was to examine the impact of self-efficacy in the prevention of sexually transmitted diseases (STD), knowledge of and susceptibility to STD, and the role of gender in sexual autonomy. Methods: Data were collected from 267 college students using self-report questionnaires during the period from the first to the twentieth of June 2015. Data were analyzed using $x^2$ test, Fisher's exact test, t-test, Pearson correlation coefficients, simple and multiple regression techniques with the PASW/WIN 20.0 program. Mediation analysis was performed according to the Baron and Kenny method and Sobel test. Results: In male students, self-efficacy for STD prevention showed a full mediating effect in the relationship between STD susceptibility and sexual autonomy (${\beta}$=-.08, p=.370). But in female students, it had a partial mediating effect (${\beta}$=-.25, p=.001). And self-efficacy for STD prevention showed partial mediating effects in the relationship between knowledge of STD and sexual autonomy in the both male (${\beta}$=.25, p=.005) and female students (${\beta}$=.33, p<.001). Conclusion: To enhance college students' sexual autonomy, it may be useful to build effective strategies enhancing students' knowledge about and susceptibility to STD and to develop a self-efficacy promotion program for college students.

• 디지털융복합연구
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• 제18권9호
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• pp.221-228
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• 2020

본 연구의 목적은 간호대학생들의 성지식, 피임태도와 성인지 감수성과의 관련성을을 알아보고자 시행되었다. 자료수집 기간은 2019년 11월부터 12월까지이며, U시의 간호대학생 169명을 대상으로 하여 구조화된 설문지를 이용하여 자료를 수집하였고, 자료의 분석은 기술통계, t-test, ANOVA, Scheffe test, Pearson's 상관관계 분석, 다중회귀 분석을 이용하였다. 연구결과 성인지 감수성은 간호대학생들의 피임태도(r=0.357, p<0.001)에 유의한 상관이 있고, 피임태도가 성인지 감수성에 영향을 미치는 것(β=0.356, p<0.001)을 확인하였다. 그러므로 간호대학생의 성인지 감수성을 높이기 위해 피임태도의 정도를 높이는 프로그램의 개발과 적용이 필요하다.

• The Korean Journal of Physiology and Pharmacology
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• 제6권3호
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• pp.155-160
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• 2002

It is not known whether gender differences play a role in susceptibility to ischemic acute renal failure. Thus, we examined if there were any differences in susceptibility between male and female mice to kidney ischemic injury, and if so, whether it is due to differences in mitogen activated protein kinases (MAPKs) or inflammatory responses to ischemia. Female mice were protected against kidney ischemia when compared with males. Thirty minutes of bilateral ischemia resulted in marked functional and morphological damages in males, but not in females. The ischemia-induced phosphorylation of c-jun N-terminal stress-activated protein kinases (JNKs) was higher in males than in females. Phosphorylation of extracellular signal-regulated kinases (ERKs) was lower in males than in females. Post- ischemia medullary infiltration of RAW 264.7 cell, a monocyte-macrophage cell, and intercellular adhesion molecule-1 (ICAM-1) were greater in males than in females. In conclusion, males were much more susceptible to ischemia than females. The enhanced propensity to ischemic injury in males was correlated with greater activation of JNKs, greater expression of ICAM-1, and greater trapping of leukocytes in the medulla.

• 한국의류학회지
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• 제39권6호
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• pp.799-811
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• 2015

This study examined factors that influenced susceptibility to dyadic influences between opposite-gender couples on making apparel purchase decisions. This study focused on main effects of couple identity, product knowledge, clothing involvement and gender, and the interaction effects of gender with other factors for normative and informational influences. A survey was conducted on 155 males and 166 females currently married or in a relationship between the ages of 20 and 50 living in South Korea. For normative influence, the main effects of joint couple identity and clothing involvement (fashion interest, symbolism, and pleasure), and the interaction between gender and clothing involvement (fashion interest) were significant. The interaction between gender and other variables were insignificant. For informational influence, the main effects of partner's product knowledge, pleasure, and gender as well as the interaction effects between fashion interest and gender, and between pleasure and gender were significant. Marketers may find implications from the study results on how couples influence each other in making apparel purchase decisions.

• 근관절건강학회지
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• 제22권1호
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• pp.20-29
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• 2015

Purpose: The study was undertaken to investigate effects of susceptibility to musculoskeletal disorder, social support, and environmental aids on exercise adherence intention and to identify factors contributing to exercise adherence intention among university students. Methods: The study was a descriptive study with 277 students from 3 universities. Data were collected from March 5 to May 30, 2014 using a structured self-report questionnaire. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson correlation coefficients, and Hierarchical multiple regression. Results: The explanatory power of the predictive model involving the demographic factors, susceptibility to musculoskeletal disorder, social support, and environmental aids was 29%, and the subjects' gender, health concern, experience of musculoskeletal injury, regular exercise, and social support were identified as main factors having influence. Conclusion: The results of this study will be helpful in understanding the importance of environmental factors for increasing physical activities and will be used as basic data for development of exercise programs to increase exercise adherence intention for their continuous exercise.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6971-6978
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• 2013

Background: Smoking among adolescents has been linked to a variety of adverse and long term health consequences. "Susceptibility to smoking" or the lack of cognitive commitment to abstain from smoking is an important predictor of adolescent smoking. In 2008, we conducted a study to determine the psycho-sociological factors associated with susceptibility to smoking among secondary school students in the district of Kota Tinggi, Johor. Materials and Methods: Two thousand seven hundred students were randomly selected by proportional stratified sampling. Analyses on 1,736 non-smoking students revealed that prevalence of adolescents susceptible to smoking was 16.3%. Results: Male gender (aOR=2.05, 95%CI= 1.23-3.39), poor academic achievement (aOR 1.60, 95%CI 1.05-2.44), ever-smoker (aOR 2.17, 95%CI 1.37-3.44) and having a smoking friend (aOR 1.76, 95%CI 1.10-2.83) were associated with susceptibility to smoking, while having the perception that smoking prohibition in school was strictly enforced (aOR 0.55, 95%CI 0.32-0.94), and had never seen friends smoking in a school compound (aOR 0.59, 95%CI 0.37-0.96) were considered protective factors Conclusions: These results indicate that follow-up programmes need to capitalise on the modifiable factors related to susceptibility to smoking by getting all stakeholders to be actively involved to stamp out smoking initiation among adolescents.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2265-2270
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• 2016

Background: Chronic myeloid leukemia (CML) is one of the most frequent hematopoietic malignancies in the elderly population; however, knowledge is limited regarding the genetic factors associated with increased risk for CML. Polymorphisms affecting microRNA (miRNA) biogenesis or mRNA:miRNA interactions are important risk factors in the development of different types of cancer. Thus, we carried out a case-control study to test the association with CML susceptibility of gene variants located in the miRNA machinery genes AGO1 (rs636832) and GEMIN4 (rs2740348), as well as in the miRNA binding sites of the genes BRCA1 (rs799917) and KRAS (rs61764370). Materials and Methods: We determined the genotype of 781 Mexican-Mestizo individuals (469 healthy subjects and 312 CML cases) for the four polymorphisms using TaqMan probes to test the association with CML susceptibility. Results: We found a borderline association of the minor homozygote genotype of the KRAS_rs61764370 polymorphism with an increased risk for CML susceptibility (P = 0.06). After gender stratification, this association was significant only for women (odds ratio [OR] = 13.41, P = 0.04). The distribution of the allelic and genotypic frequencies of the four studied SNPs was neither associated with advanced phases of CML nor treatment response. Conclusions: To the best of our knowledge, this study is the first to show a significant association of the KRAS_rs61764370 SNP with CML. To further determine such an association of with CML susceptibility, our results must be replicated in different ethnic groups.

• 대한임상검사과학회지
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• 제39권1호
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• pp.7-18
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• 2007

A total of 1,780 isolates of Enterococcus spp. were isolated from 63,133 clinical specimens from Dec 1, 2005 to Nov 1, 2006 in "C" hospital. Isolation frequencies of Enterococcus spp. were 50.9% for E. faecalis, 41.7% for E. faecium, and 7.4% for other Enterococcus spp. containing E. avium, E. gallinarum, E. casseliflavus, E. durans, E. hirae, and E. raffinosus. There were no significant difference between gender, but according to the age group analysis, Enterococcus spp. were more frequently isolated in patients over 50 years old (20.0~24.6%) than those isolated from the patients under the age of 0~49 (1.3~9.4%). In monthly analysis, Enterococcus spp. were the most frequently isolated in April (11.9%), but presented at lowest frequency in February (5.2%). Seasonal analysis did not show a significant difference. Over half of enterococci were isolated from random urine (44.9%) and catherterized urine (15.7%). Frequencies of vancomycin resistant E. faecalis and E. faecium were 0.1% and 31.0%, respectively. Teicoplanin resistant Enterococcus was 13.3% in E. faecalis, 17.6 % in E. faecium. The Enterococcus species showing over 80% susceptibility against antimicrobial agents were E. faecalis, E. durans and E. hirae in vancomycin; E. faecalis, E. gallinarum, E. casseliflavus, E. durans and E. hirae in ampicillin. The antimicrobial agent showing susceptibility against whole group of Enterococcus species was only linezolid (95.9%), and a selection of antimicrobial agent is necessary to do essential performance identification and susceptibility tests.

• 대한불안의학회지
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• 제15권2호
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• pp.122-126
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• 2019

Objective : Dynamic proteolysis, through the ubiquitin-proteasome system, is an important molecular mechanism for the constant regulation of synaptic plasticity and stress responses in humans. In this study, we examined whether genetic variants in the ubiquitin-specific peptidase (USP) genes were associated with psychological traits of resilience and susceptibility to neuropsychiatric disorders for each gender. Methods : A total of 344 Korean healthy youths (190 males, 154 females) were included in the study. A genotyping of rs2241646 of USP2 and rs346006 of USP46 was performed. The Connor-Davidson Resilience Scale and Brief Fear of Negative Evaluation Scale were administered for measuring trait resilience and social anxiety, respectively. The genetic associations of the USP variants were tested using multiple analyses of covariance with psychological traits as dependent variables after controlling for age in each gender. Results : For USP2 rs2241646, women with the TT genotype showed significantly higher resilience and lower social anxiety, as compared to those carrying the C allele. There were no associations between USP46 rs346005 and the psychological traits in both genders. Conclusions : The present study showed a possible genetic association between the USP2 rs2241646 and stress resilience and trait anxiety in women. The findings suggest that ubiquitin-proteasome system may be related to the resilience and susceptibility to stress-related neuropsychiatric disorders such as anxiety disorders, possibly through the regulation of dynamic proteolysis responses to stress.

• 대한임상검사과학회지
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• 제51권2호
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• pp.155-163
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• 2019

검사는 2010년부터 2017년까지 162,551 검체중 11,233 검체(6.9%)가 배양 양성이었으며, 이중 11,865 균주가 배양되었다. 배양된 균종 중 그람양성구균이 47.8%, 그람음성간균 38.8%, 그람양성간균 4.2%, 진균 6.8%, 혐기성균이 2.3%를 나타냈다. 배양결과를 성별로 비교하면 남성에서 분리된 균이 55.0% (2,732/4,969)로 여성에서 분리된 45.0% (2,237/4,969) 보다 많았다. 또한 연령별로는 70대가 28.7% (1,426/4,969)로 가장 많이 분리되었으며, 10대의 1.2% (62/4,969)와 많은 차이를 보였다. MRSA에 대한 내성률은 2016년 66.7%에서 2017년에는 46.8%로 많은 감소를 보였으며, E. faecium의 vancomycin 내성률은 35.0% (48/137)로 나타났다. 한편 장내세균에서 E. coli의 ESBL 양성률은 2010년 17.2%에서 2017년 28.8%로 증가하였으나, K. pneumoniae에서는 오히려 양성률이 감소하였다. P. aeruginosa의 MRPA는 11.8% (14/119), A. baumannii에서의 MRAB는 64.3% (161/252)로 높은 내성을 나타내었다. 혈액 검체에서 분리되는 미생물의 균종과 항균제 감수성 양상은 시기, 지역 및 대상환자 등에 따라 다르므로 병원균을 주기적으로 분석하고 이에 대한 항균제 감수성 정도의 변화양상을 파악하는 것이 병원에서 내성균의 감독과 조절에 큰 도움이 될 것으로 판단된다.