• Korean Journal of Head & Neck Oncology
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• v.25 no.1
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• pp.8-11
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• 2009

Background and Objectives : In the TNM 6th classification system, extrathyroidal invasion of differentiated thyroid carcinoma has been classified into T3(minimal invasion), T4a(extended invasion), and T4b(more extensive unresectable invasion) according to the degree and it has been recognized as an important prognostic factor. In this study, we investigated the prognostic significances of minimal extrathyroidal invasion in papillary thyroid carcinoma(PTC). Material and Methods : We retrospectively studied 221 patients who are underwent thyroidectomy due to PTC from September 2003 to December 2006. Fifty-four(24.4%) patients had a PTC with minimal extrathyroidal invasion(Group A) and 167(75.6%) patients had a PTC without extrathyroidal invasion(Group B). The existence of minimal extrathyroidal invasion was based on operative and pathological findings. Results : Minimal extrathyroidal invasion in PTC was related to tumor size, lymph node metastasis, and operative method(p<0.001). But, there is no significant difference in age, gender, and multifocality between Group A and B. Hashimoto's thyroiditis was observed more frequently in Group B(p=0.019). Conclusion : These findings suggest that minimal extrathyroidal invasion is related to poor prognostic factors in PTC. Therefore, aggressive surgical approach is required when there is evidence of minimal extrathyroidal invasion in preoperative radiologic examination or operative finding.

• Radiation Oncology Journal
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• v.38 no.1
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• pp.11-17
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• 2020

Purpose: Definitive radiotherapy remains a primary treatment option for early stage glottic cancer. Intensity-modulated radiation therapy (IMRT) has emerged as the standard treatment technique for advanced head and neck cancers, whereas three-dimensional conformal radiotherapy (3D-CRT) has remained standard for early glottic cancers. We used the National Cancer Database (NCDB) to identify predictors of IMRT use and effect on outcome in these patients. Materials and Methods: We queried the NCDB from 2004-2015 for squamous cell carcinoma of the glottic larynx staged Tis-T2N0 treated with radiation alone. Logistic regression was used to identify predictors of IMRT. Cox regression was used to identify factors predictive of overall survival. Propensity matching was conducted to account for indication bias. Results: We identified 15,627 patients, of which 11% received IMRT. IMRT use rose from 2% in 2004 to 16% in 2015. Predictors of IMRT include: increased comorbidity, T2 stage, urban location, chemotherapy, treatment at an academic center, and later treatment year. Predictors of improved survival were female gender, higher income, lower stage, no chemotherapy, academic facility, and more remote year. There was no difference in survival between 3D-CRT and IMRT across all stages. Conclusions: The rate of IMRT use for early stage glottic laryngeal cancer has increased over time. There was no difference in outcome in patients receiving IMRT versus 3D-CRT across the cohort.

• Journal of Cardiovascular Imaging
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• v.26 no.4
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• pp.229-237
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• 2018

BACKGROUND: Statins are thought to have little effect on the progression of aortic stenosis, but the data on their role in patients with aortic valve sclerosis (AVS) are limited and inconsistent. METHODS: We retrospectively analyzed 541 consecutive patients (214 men, age: $70{\pm}11$ years) with AVS. Each patient underwent two or more electrocardiography examinations at least 6 months apart at Kangwon National University Hospital from August 2010 to August 2015. AVS is defined as irregular thickening of the leaflets, focal increases in echogenicity and minimal elevation of the peak aortic valve velocity (> 1.5 and < 2 m/s). The progression rate of AVS was expressed as the increase in peak velocity per year (m/s/yr). RESULTS: The mean follow-up duration was $24.9{\pm}13.3$ months in the statin-treated group and $24.1{\pm}12.4$ months in the non-statin-treated group (p = 0.460). There were no differences between the statin-treated and non-statin-treated groups in mean age, gender or smoking status. Relative to the non-statin-treated group, a higher number of patients in the statin-treated group had hypertension, diabetes, ischemic heart disease, and stroke. The progression rate of AVS did not differ between the statin-treated and non-statin-treated groups ($0.012{\pm}0.340m/s/yr$ vs. $0.014{\pm}0.245m/s/yr$, p = 0.956). Multivariate analysis showed initial peak aortic jet velocity was significantly associated with AVS progression (${\beta}=0.153$, p = 0.009). CONCLUSIONS: Our study demonstrated that statins had no effect on the progression of AVS. However, well-designed studies are needed to define the prognosis and management of AVS.

• Journal of Physiology & Pathology in Korean Medicine
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• v.36 no.3
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• pp.94-99
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• 2022

The discovery of biomarkers related to pattern identification (PI), the core diagnostic theory of Korean medicine (KM), is one of the methods that can provide objective and reliable evidence by applying PI to clinical practice. In this study, 40 diabetic patients and 41 healthy control subjects recruited from the Korean medicine clinic were examined to determine the human electrical response related to the deficiency pattern, a representative pattern of diabetes. Qi-Blood-Yin-Yang deficiency pattern scores, which are representative deficiency patterns for diabetes mellitus, were obtained through a questionnaire with verified reliability and validity, and the human electrical response was measured non-invasively using a bioimpedance meter. In ANCOVA analysis using gender as a covariate, the 5 kHz frequency resistance and 5-250 kHz frequency reactance were significantly lower in the diabetic group than in non-diabetic control group. In addition, the multiple regression analysis showed a positive correlation (R2=0.11~0.19) between the Yang deficiency pattern score and resistance value for the diabetic group; the correlation was higher at higher frequencies of 50kHz (R2=0.18) and 250kHz (R2=0.19) compared to 5kHz(R2=0.11). In contrast, there was no such significant association in the control group. It implies that bioimpedance resistance measured at finite frequencies may be useful in predicting Yang deficiency, which is closely related to diabetic complications by reflecting the decrease in body water content and metabolism. In the future, large-scale planned clinical studies will be needed to identify biomarkers associated with different types of PI in diabetes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.1
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• pp.196-201
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• 2014

This study intends to investigate alcohol use disorder in the elderly in rural area. The subjects were 212 elderly people. Alcohol use disorder was defined as a score of more than 10 points on the AUDIT-K. The collected data were analyzed descriptive statistics, chi-square test and t-test using SPSS 19.0 program. The alcohol use disorder in the elderly in rural area were 18.4%. The alcohol use disorder was statistically significant difference according to gender, age, inmate, scholarship, religion, job and smoking. The alcohol use disorder correlated positively with depression. To prepare the aging society, the government should make preparation prorgram for elderly alcoholics.

• Journal of Families and Better Life
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• v.23 no.5 s.77
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• pp.1-14
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• 2005

The purpose of this study is to examine the relationship between parental support and senior high school students' career development. For this study, the data was gathered from 1,468 students in 15 classes(different divisions) at 9 high schools (3 Academic high schools, 3 Industrial technology schools, 3 Vocational high schools) in Seoul. The results of the study were as follows: 1. There is significant difference, statistically, in the relation between parental support and career development by gender. 2. As for the division factor, the recognition level of parental supports was higher in girls than in boys and the average of their career development level was also higher. 3. As for the division factor, the recognition level of parental supports was most highest in academic high school students than in other groups and the average of their career development level was also the highest. 4. There were significant correlations between the parental supports and career decision-making self-efficacy, vacational identity, career decision. 5 As for the effects of parental support on the student's career development, career decision-making self-efficacy was higher than other vacational identity, career decision.. The $R^2$ value was weak but still statistically significant.

• Child Health Nursing Research
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• v.26 no.1
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• pp.82-89
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• 2020

Sudden infant death syndrome (SIDS) in Korea remains a poorly-understood subject for both professionals and the public. Recent reports have emphasized ethnic differences in SIDS rates, suggesting that making adjustments in child-rearing practices may contribute substantially to SIDS reduction. Two of the three major risk factors for SIDS-vulnerability of the infant and exogenous factors-need to be understood in particular depth due to their broad scope and sociocultural grounding. This paper presents substantial issues regarding preterm birth and male gender on infants' vulnerability to SIDS in Korea. Practices of caring for healthy infants are addressed in the context of sleeping practices, including sleeping position, bedding arrangements, sleeping on the floor, the back-to-sleep position, high indoor temperatures and ondol floor heating, and swaddling. Professional and social awareness about how to reduce SIDS should be raised by promoting a better understanding of risk factors in the context of ethnic and cultural variations in child-rearing practices.

• Journal of the Korean Home Economics Association
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• v.50 no.4
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• pp.73-87
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• 2012

The purpose of this study was to analyze the difference in school adjustment and future time perspectives, according to the characteristics in regards to the role models of the children in institutional facilities. Data for this study were obtained from a survey conducted on 310 children aged 11-13. Data were analyzed using various statistical methods such as frequency analysis, chi-square test, t-test, one-way ANOVA, and one-way ANCOVA. The main findings of this study were as follows. First, overall, the majority of children selected entertainers and celebrities as their role models. Also, we found differences in children's school adjustment according to their background variables (gender, staying with their siblings, and having parents alive). Second, having role models was significantly related to the levels of school adjustment as well as the positive future time perspectives of the children. Based on the results, practical implications for children in institutional care were discussed.

• Journal of Korean Public Health Nursing
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• v.27 no.3
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• pp.608-618
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• 2013

Purpose: The purpose of this study was to identify the current status of cybersex addiction, demographic factors influencing the level of cybersex addiction, and relationships between sexual knowledge, sexual attitude, and cybersex addiction among Korean college students. Methods: Using a cross-sectional study design, 6,000 college students were recruited through proportional quota sampling from May 2011 to October 2011. Results: Almost 10 percent(9.3%) of the participants had moderate or severe addiction to cybersex. The level of cybersex addiction differed significantly according to gender, major, and economic status. Significant association was observed between sexual knowledge, sexual attitude, and cybersex addiction. Conclusion: The significant demographic factors mentioned above, as well as sexual knowledge and attitude should be factored in when designing interventions for cybersex addiction among college students. Conduct of more qualitative and longitudinal research on this topicis needed in order to prevent and to intervene in cybersex addiction among college students.

• Women's Health Nursing
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• v.7 no.4
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• pp.508-517
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• 2001

The purposes of this study are to investigate marital satisfaction according to demographic characteristic, division of household labor, and awareness of gender discrimination, and to explore influences of demographic and other variables on marital satisfaction. Social statistics survey data which collected in 1998 by ministry of statistics were used for secondary analysis of this study. Marital satisfaction was measured by questionnaire which was consisted in 7 items, including satisfaction with general family life, relationship with their own parent and parent-in-law, relationship with brothers and sisters, relationship with their children, and economic living status. These are measured by 5-point Likert scale. Independent variables are age, education, employment status, having their own house or not, No. of children under school age, parents living or not, perception of sexual discrimination, and division of household labor. The findings of this study show that there are significant differences of marital satisfaction by all independents variables, and all independent variables except employment have significant influences on marital satisfaction. People who are younger, received higher education, have their own house, have more children under schoolage and whose parent are living in the world, show higher marital satisfaction. The more husbands participate to household labor, the better marital satisfaction. In case of perception of sexual discrimination, main effect is not significant, but interaction effect with age is significant. Interaction effect between age and education is also significant. 32.52% of the variance in marital satisfaction were accounted for by these variables.