• Title/Summary/Keyword: gel materials

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Porous Hyaluronic Acid-Gelatin Loaded Sponge Biphasic Calcium Phosphate Scaffold for Bone Implant Application

  • Nguyen, Thuy Ba Linh;Kim, Shin-Woo;Min, Young-Ki;Yang, Hun-Mo;Lee, Byong-Taek
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.10a
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    • pp.35.2-35.2
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    • 2011
  • In this study, hyaluronic acid (HyA) - Gelatin (Gel) hydrogels were prepared at ratio of 15:85 with the goal of obtaining a high uniform porosity and porous biocompatibility scaffold for bone tissue engineering applications. In order to develop a proper scaffold for bone implant application, a HyA-Gel hydrogel loaded in sponge Biphasic Calcium Phosphate (BCP) was prepared. To assay the cytocompatibility and cell behavior on the HyA-Gel hydrogel and HyA-Gel/BCP scaffold, cell attachment and spreading of MSCs seeded on the scaffolds were studied. An invivo study was performed for HyA-Gel/BCP scaffolds after 1 and 3 months implantation. Our results provide a novel and simple method to obtain an adequate scaffold for osteoblast cells and indicate that HyA-Gel hydrogel and HyA-Gel/BCP scaffold could be a good candidate for bone tissue engineering scaffolds.

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A Study on the Infiltration Porperties of Cement Grout Material (시멘트계 주입재의 침투특성에 관한 실험적 연구)

  • 천병식;신동훈;이종욱;김진춘;이준우;안익균;이승범
    • Proceedings of the Korean Geotechical Society Conference
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    • 2002.03a
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    • pp.297-304
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    • 2002
  • This study is about penetrability of Micro Cement(MC) used for ground improvement. In this study, the characteristics of chemical grouting such as solidification, penetrability were analyzed experimentally by changing permeability of ground, grain size and relative density of grout material. For evaluating applicability of grout material, solidification test and penetrability test were performed. From the results of the tests, effective solidification ratio and penetrability ratio of MC was each 75%, 86% to be excellent when ground permeability was in the range of 10$^{-2}$ and 10$^{-4}$ cm/sec. Otherwise, those of Ordinary Portland Cement(OPC) were both lower than 50% to be poor. When penetrability of grout material is needed for improvement of dam foundation and soft ground, application of MC Is much superior to that of the other materials. The results of the grouting tests in the water flowing ground show that solidification effect of long gel-time grout material is excellent as injection pressure increases when groundwater velocity is relatively low. But when groundwater velocity is relatively high, solidification effect of long gel-time grout material is very poor because most grout materials are outflowed. Therefore, as groundwater velocity is high, effective solidification ratio of long gel-time grout material is better than that of short gel-time grout material, also penetration distance of long gel-time grout material is longer than that of short gel-time grout material.

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Promoted Bone Regeneration by Nanoparticle-Type Sustained Release System of BMP-2 in Hydrogel

  • Chung, Yong-Il;Lee, Seung-Young;Tae, Gi-Yoong;Ahn, Kang-Min;Jeon, Seung-Ho;Lee, Jong-Ho
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.264-264
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    • 2006
  • The nanoparticle-hydrogel complex as a new bone defect replacement matrix, which is composed of the nanoparticles for the sustained release of BMP and the hydrogel for filling the bone defect site and playing a role as a matrix where new bone can grow, is presented. In vivo evaluation of bone formation was characterized by soft X-ray, MT staining, and calcium assay, based on the rat calvarial critical size defect model. The effective bone regeneration was achieved by the BMP-2 loaded nanoparticles in fibrin gel, compare to bare fibrin gel, the nanoparticle-fibrin gel complex without BMP-2, or the BMP-2 in fibrin gel, in terms of the new bone area and the gray level in X-ray, the bone marrow are, and the calcium content in the initial defect site. These findings suggest that the BMP-2 loaded nanoparticle-fibrin gel complex can a promising candidate for a new bone defect replacement matrix.

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Synthesis of $SiO_2$ nanoparticles self-assembled thin film by organic.inorganic hybrid method

  • Hu, Yi;Lyu, Jhong-Ming;Liu, Tung-Cheng;Liu, Jiun-Shing
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.1538-1541
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    • 2009
  • Amphiphobic thin films for touched panel application was prepared by $SiO_2$ nanoparticles self-assembled nanostructure. Silicon dioxide nano spheres were prepared by sol-gel method and well dispersed in a solution with surfacants of low surface energy. Nanostrcture thin films were obtained by spin coating technologies.

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Gate dielectric based on organic-inorganic hybrid polymer in organic thin-film transistors

  • Lee, Seong-Hui;Jeong, Sun-Ho;Moon, Joo-Ho
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.727-729
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    • 2007
  • Inorganic-organic hybrid polymer provides various advantages including low-temperature process, high dielectric constant and direct photo-patterning. The hybrid dielectric was synthesized by the sol-gel process in which an acid-catalyzed solution of Si alkoxide and Zr alkoxide was used as a precursor. The electrical performance of transistors with hybrid dielectric was investigated.

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