• Journal of the Korean Society of Radiology
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• v.16 no.6
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• pp.779-786
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• 2022

This study is designed to examine the effects of Dioscorea Quinqueloba extract as a natural radiation protection agent on the prostate and heart of male rats. Dioscorea Quinqueloba extract is well known to prevent the male-specific disease and heart disease. In this study, the Gamma-ray 10 Gy was irradiated in whole body of male rat to identify radioprotective effect by Dioscorea Quinqueloba extract. After irradiation, tissue change, SOD (Superoxide Dismutase) activity changes and hematological changes were observed. DQ+IR group showed higher lymphocyte, white blood cell, platelet levels than the IR group. In the NC and DQ groups, the number of prostate gland cells and the gap between cells were relatively narrow. But in the IR group, the cells died significantly and the gap widened. In the DQ+IR group, the gap between cells increased similarly to the IR group, but the number of dead cells was noticeably smaller. In the NC and DQ groups, the cardiovascular and myocardium are clearly separated, and cell nuclei are in good condition. But in the IR group, the cardiovascular and myocardium boundaries were disrupted, and the number of dead cell nuclei was high. In the DQ+IR group, although the boundaries were widened, but not disrupted and the number of dead cell nuclei was high. Therefore, Dioscorea Quinqueloba extract is judged to have radioprotective properties for the prostate and cardiovascular.

• Journal of the Korean Society of Radiology
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• v.18 no.2
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• pp.161-169
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• 2024

This study confirmed the radioprotective effects of a mixed extracts of Hottuynia, Perilla Frutescens, and Camellia Sinnensis as natural radioprotectors on the prostate, small intestine, and liver of SD rats. It is known that Hottuynia, Perilla Frutescens, and Camellia Sinnensis have antioxidant effects on the prostate, small intestine, and liver, respectively.In this study, SD rats were irradiated with 8 Gy of gamma rays to confirm the radioprotective effects of a mixed extracts of Hottuynia, Perilla Frutescens, and Camellia Sinnensis. After radiation irradiation, histological analysis of the prostate, small intestine, and liver was performed. After radiation irradiation, histological analysis of the prostate, small intestine, and liver was performed. In the case of the prostate, the HPC+IR Group had less prostate damage and better recovery due to radiation compared to the IR Group. It was confirmed that the prostate size of the HPC+IR Group was 11.48%p and 24.54%p higher than the IR Group on 1st and 7th days. In the case of the small intestine, the HPC+IR Group had less radiation-induced small intestinal damage and recovery was better than the IR Group. The length of small intestine villus in the HPC+IR Group was confirmed to be 23.73%p and 24.27%p higher than the IR Group on the 1st and 7th days. In the case of the liver, the HPC+IR Group had less liver damage due to radiation and had better recovery than the IR Group. This was confirmed through the hepatic portal vein and surrounding cells. The results of this study are considered to be used as basic data for research on natural radiation protection using mixed extracts.

• Nuclear Engineering and Technology
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• v.56 no.4
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• pp.1526-1531
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• 2024

¹³¹I is a fission product produced in a nuclear reactor by irradiating tellurium dioxide, with a half-life of 8.02 day. The most important and widely used method for making ¹³¹I is irradiation using a nuclear reactor and post-irradiation followed by dry distillation. The advantage of the dry distillation process is that the process and the equipment are relatively simple, namely TeO₂ (m.p. 750 ℃), which can withstand heating during reactor irradiation. Based on TeO₂ irradiation by neutron following the technique of dry distillation was explained for production of ¹³¹I on a large scale. A dry distillation followed the radioisotope production operation using the 30 MW GA Siwabessy nuclear reactor to meet national demand. TeO₂ targets are 25 and 50 g irradiated for 87-100 h. The resulting ¹³¹I activity is 20.29339-368.50335GBq. According to the requirements imposed on the radionuclide purity of the preparation, the contribution of ¹³¹I training in the resulting preparation was not less than 99.9 %