• Title/Summary/Keyword: gain size

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Growth Rate of Transgenic Pigs and Size of Pig Hearts for Xenotransplantation to Cynomolgus Monkey

  • Ock, Sun A;Oh, Keon Bong;Hwang, Seongsoo;Lee, Jungkyu;Kim, Youngim;Moon, Sun-Woung;Kwon, Dae-Jin;Yun, Ik Jin;Park, Eungwoo
    • Journal of Embryo Transfer
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    • v.29 no.4
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    • pp.333-337
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    • 2014
  • To compensate for the critical shortage of human organs for allotransplantation, xenotransplantation studies using genetically modified pigs are being performed in Korea. Two types of pigs that are used are ${\alpha}1,3$-galactosyltransferase gene knockout (GalT KO) pigs and GalT KO+hCD46 (human complement regulatory protein) pigs. The present study measured the gestation time, birth weight, daily growth rate, and heart weight of both kinds of transgenic minipigs. The gestation period for both types of pigs was 117~119 days. There was no difference in the body weight of GalT KO (-/+) and GalT KO (-/-) piglets, but GalT KO+hCD46 ($-^{hCD46+}/+$) pigs were significantly heavier at birth than were GalT KO+hCD46 ($-^{hCD46+}/-^{hCD46+}$) pigs. During the first 10 weeks of life, the daily weight gain of GalT KO+hCD46 ($-^{hCD46+}/-^{CD46+}$) piglets, which are considered the optimal type for xenotransplantation, was 0.19 kg. The weight of hearts from GalT KO piglets up to two months of age was affected more by body weight than by age. Transgenic pigs showed no differences in gestation period or reproductive ability compared with normal pigs. These results comprise basic data that may be used in xenotransplantation studies and transgenic animal production in Korea.

The Effect of Ocean Acidification on Early Growth of Juvenile Oliver Flounder (Paralichthys olivaceus): in situ Mesocosm Experiment (해양산성화가 넙치의 초기발달에 미치는 영향: 현장 메조코즘(mesocosm) 실험)

  • Shim, Jeong Hee;Kwon, Jung-No;Park, Joo Myun;Kwak, Seok Nam
    • Korean Journal of Environmental Biology
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    • v.31 no.4
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    • pp.353-361
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    • 2013
  • An in situ mesocosm experiment was designed to investigate how exposure to ocean acidification by increased carbon dioxide affected the growth of juvenile oliver flounder (Paralichthys olivaceus). A total of 447 individuals were reared in the mesocosm experimental devices deployed at sandy-muddy bottom in the southern coast of East Sea for 43 days and divided into two groups: treatment group (223 individuals, $6.32{\pm}0.75$ cm, high-$CO_2$ environment) and control group (224 individuals, $6.34{\pm}0.84$ cm, natural $CO_2$ environment). The average values of pH and $CO_2$ concentration in the treatment device were $7.63{\pm}0.13$ and $1660{\pm}540$ ${\mu}atm$, respectively, while those in the control device were $8.07{\pm}0.05$ and $514{\pm}65$ ${\mu}atm$, respectively. There was no significant difference in mortality rate between treatment and control group, and the mortalities in two groups gradually decreased during the study period. But, the increase of size and weight of juvenile oliver flounder was higher in control group than treatment group, i.e., weight gain or growth rate was higher in control group. These results suggested that high $CO_2$ environments could have a significant negative influence on the early growth of juvenile oliver flounder.

Parks' Lighting Measurement and Analysis for Lighting Plan around Waterfront in Jeju (제주 수변공간 조명계획을 위한 공원조명 실측과 해석)

  • Kim, Eel-Hwan;Oh, Seong-Bo;Ko, Bong-Woon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.116-122
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    • 2017
  • The environmental lighting of a city advances its landscape standards and the city's touristic value because the lighting can help improve the city's safety and security as well as its esthetic value. The types of parks in cities vary in size and function and should be reflected carefully in lighting planning to gain the best effect. The importance of city lighting has been increased in recent years due to the expanded span of urban night life. Lighting systems around rivers and coastal waterfronts in cities play an important role not only in their functional aspects, such as safety and security, but also in boosting the city's identities. This paper performed comparison analysis among Tsim Sha Tsui Promenade in Hong Kong, Fukuoka Nakagawa Park in Japan, and the walking path in Hamdeok Beach in Jeju City, Korea. According to the evaluation, Hong Kong is excellent in 8 evaluation criteria for park lighting so that the city shows its superior installation and management. Fukuoka is also good by being analyzed as 'fair' in 5 criteria. Finally, Jeju is judged as inferior overall by showing 'poor' in several criteria. The paper shows how they differ in their environment lighting characteristics and aims to suggest stable lighting planning strategies for seaside parks in Jeju so the citizens and visitors of Jeju can enjoy the beautiful sceneries and nighttime activities.

A Cluster-Organizing Routing Algorithm by Diffusing Bitmap in Wireless Sensor Networks (무선 센서 네트워크에서의 비트맵 확산에 의한 클러스터 형성 라우팅 알고리즘)

  • Jung, Sangjoon;Chung, Younky
    • Journal of Korea Multimedia Society
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    • v.10 no.2
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    • pp.269-277
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    • 2007
  • Network clustering has been proposed to provide that sensor nodes minimize energy and maximize a network lifetime by configuring clusters, Although dynamic clustering brings extra overhead like as head changing, head advertisement, it may diminish the gain in energy consumption to report attribute tasks by using cluster heads. Therefore, this paper proposes a new routing algorithm which configures cluster to reduce the number of messages when establishing paths and reports to the sink by way of cluster heads when responding sens ing tasks. All sensor nodes only broadcast bitmap once and maintain a bitmap table expressed by bits, allowing them to reduce node energy and to prolong the network lifetime. After broadcasting, each node only updates the bitmap without propagation when the adjacent nodes broad cast same query messages, This mechanism makes nodes to have abundant paths. By modifying the query which requests sensing tasks, the size of cluster is designed dynamically, We try to divide cluster by considering the number of nodes. Then, all nodes in a certain cluster must report to the sub- sink node, The proposed routing protocol finds easily an appropriate path to report tasks and reduces the number of required messages for the routing establishment, which sensor nodes minimize energy and maximize a network lifetime.

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Analysis of Sedimentation and Erosion Environment Change around the Halmi-island, Anmyeondo in West Coast of Korea (안면도 할미섬 주변의 침식·퇴적환경 변화 분석)

  • KIM, Jang-soo;JANG, Dong-Ho
    • Journal of The Geomorphological Association of Korea
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    • v.19 no.2
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    • pp.123-132
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    • 2012
  • In this study, we analyzed sedimentation and erosion environment around Halmiseom on Anmyeon Island using wind direction and wind speed data, gain size analysis data and datum-point measured values. To observe changes in sedimentation and erosion environment around Halmiseon, we installed datum points at 12 locations around Halmiseom and carried out at total of 32 field measurements from May 16th, 2010 to May 8th, 2012. The field measurement results showed that H-3, H-4, H-5 and H-9 points are dominated by sedimentation environment, and H-7, H-8, H-10, H-11 and H-12 points are dominated by erosion environment. Meanwhile, sedimentation and erosion appeared alternately at H-2 and H-6 points. These results indicate that a bank installed in the southwest side of Halmiseom prevented sand of the beach from moving to the northeast side, leaving the sand of the beach being deposited at the sites, and the northeast side, where sand was not provided from beach ridge of Halmiseon was dominated by sedimentation. That is, the southwest side of Halmiseom was dominated by sedimentation, but the northeast side was dominated by erosion in general. However, the opposite trends were observed at H-9 point of the northeast side and H-12 point of the southwest side. According to analysis, since H-9 point is located at the end of sand spit connected to Halmiseom, the supply of sediments by a tidal current is possible. On the other hand, it was difficult to analyze the cause of erosion in case of H-12 point located at the sand dune due to the short measurement period.

Anti-Obesity Effect of By-Product from Soybean on Mouse Fed a High Fat Diet (고지방 식이로 유도된 비만 마우스에서 대두 부산물인 순물과 침지수의 항비만 효과)

  • Park, Young Mi;Lim, Jae Hwan;Seo, Eul Won
    • Korean Journal of Plant Resources
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    • v.28 no.2
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    • pp.168-177
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    • 2015
  • Here we study the anti-obesity effects of by-product from soybean on mouse fed high fat diet. The body weight gain, visceral and subcutaneous adipose tissue weight, liver and epididymal adipose tissue weight in freeze-dried soybean-soaking-water (SSW) powder fed group showed lower level than those in high fat diet (HFD) group by determining with weight measuring and histological methods. Also, histological analyses of the liver and fat tissues of SSW grouped mice revealed significantly less number of lipid droplets formation and smaller size of adipocytes compared to the HFD group. Moreover, the levels of total serum cholesterol, LDL-cholesterol and the atherogenic index were decreased in the SSW groups. Especially, in SSW group, the levels of phosphorylation of two lipid oxidation enzymes, adenosine monophosphate-activated protein kinase (AMPK) and acetyl-CoA carboxylasse (ACC) were elevated hence that may activate fatty acid oxidation. But AST and ALT levels were not changed in blood. By micro-CT analysis of abdomen, SSW groups significantly showed a tendency to decrease visceral and subcutaneous fats as well as fat-deposited areas compared to HFD group. Taken together, we suggest that soybean soaking water has a function in ameliorating obesity through inhibiting lipid synthesis as well as stimulating fatty acid oxidation.

A Digital Phase-locked Loop design based on Minimum Variance Finite Impulse Response Filter with Optimal Horizon Size (최적의 측정값 구간의 길이를 갖는 최소 공분산 유한 임펄스 응답 필터 기반 디지털 위상 고정 루프 설계)

  • You, Sung-Hyun;Pae, Dong-Sung;Choi, Hyun-Duck
    • The Journal of the Korea institute of electronic communication sciences
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    • v.16 no.4
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    • pp.591-598
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    • 2021
  • The digital phase-locked loops(DPLL) is a circuit used for phase synchronization and has been generally used in various fields such as communication and circuit fields. State estimators are used to design digital phase-locked loops, and infinite impulse response state estimators such as the well-known Kalman filter have been used. In general, the performance of the infinite impulse response state estimator-based digital phase-locked loop is excellent, but a sudden performance degradation may occur in unexpected situations such as inaccuracy of initial value, model error, and disturbance. In this paper, we propose a minimum variance finite impulse response filter with optimal horizon for designing a new digital phase-locked loop. A numerical method is introduced to obtain the measured value interval length, which is an important parameter of the proposed finite impulse response filter, and to obtain a gain, the covariance matrix of the error is set as a cost function, and a linear matrix inequality is used to minimize it. In order to verify the superiority and robustness of the proposed digital phase-locked loop, a simulation was performed for comparison and analysis with the existing method in a situation where noise information was inaccurate.

Ngugi wa Thiong'o's Pan-Africanism: People's Memory and Alliance to Overcome Postcolonial Nations (응구기와 시옹오의 범아프리카주의 - 포스트식민 국가를 넘어서는 주변부의 기억과 연대)

  • Lee, Hyoseok
    • Cross-Cultural Studies
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    • v.42
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    • pp.107-129
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    • 2016
  • In modern history, there have been several kinds of continental unions or supranational politico-economic unions in the world, such as the United Nations, the European Union, the Union of South American Nations, the African Union, etc. Modern thinkers proposed many pan-isms on their continental base, for example, Pan-Arabism, Pan-Latin Americanism, Pan-Asianism, Pan-Celtism, etc. What is the most common in these pan-isms is that a continental union would be a politico-economic system to overcome the limits of the modern state-nation and to realize a long and happy relationship between member nations and continents. However, the concept of a supranational union differs from that of cosmopolitanism, in that the former presupposes the common cultural and historical heritage in the concerned region or continent. Ngugi wa Thinog'o' Pan-Africanism implies two keywords that are connected to his concepts such as 'decentralization' and 'African languages.' Pan-Africanism supposes that Africa may gain benefits from the union of African nations under the umbrella of anti-colonial efforts to down size the Euro-American influences. Moreover, using African languages enhances self-reliance and self-imagination among the African people. For in the former colonial regimes, the European colonial languages, such as English, French, or Portuguese, were central to the dissemination of European culture and modernity. Ngugi asserts that the African peripheralized languages could reinstate the African cultural heritage and propose an alternative to the Western modernity.

In-Band Full-Duplex Wireless Communication Using USRP (USRP 장치를 이용한 동일대역 전이중 무선통신 연구)

  • Park, Haeun;Yoon, Jiyong;Kim, Youngsik
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.30 no.3
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    • pp.229-235
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    • 2019
  • The implementation of an in-band full-duplex wireless communication system is demonstrated in this study. In the analog/RF domain, the self-interference(SI) signal is reduced using a separate antenna for the transmitter and receiver paths, and most of the SI signal is canceled in the digital domain. A software defined radio(SDR) is used to implement the in-band full-duplex wireless communication system. The USRP X310 device uses transmitting and receiving antennas. By adjusting the gain of the transmitting and receiving ends of the SDR device, the magnitude of the SI signal entering the receiving antenna, and the size of the received signal from the outside, are both set to -64 dB. To verify the in-band full-duplex wireless communication performance, the source data is image and orthogonal frequency-division multiplexing is used for modulation. A WiFi standard frame with a carrier frequency of 2.67 GHz and bandwidth of 20 MHz is used. In the received signal, the SI signal is canceled by digital signal processing and the SI signal is attenuated by up to 34 dB. OFDM demodulation was impossible when the SI signal was not removed. However, the bit error rate is reduced to $2.63{\times}10^{-5}$ when the SI signal is attenuated by 34 dB, and no error is detected in the 100 Mbit data output as a result of passing through the Viterbi decoder.

Design and Manufacture of Triple-Band Antennas with Modified Rectangular Ring and Rectangular Patch for WLAN/WiMAX system applications (변형된 사각 링과 사각 패치를 갖는 WLAN/WiMAX 시스템에 적용 가능한 삼중대역 안테나 설계 및 제작)

  • Kim, Woo-Su;Yoon, Joong-Han
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.23 no.3
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    • pp.341-348
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    • 2019
  • In this paper, a monopole type antenna applicable to WLAN and WiMAX standard frequency bands is designed and fabricated. The proposed antenna is designed to have rectangular ring and rectangular patch based on microstrip feeding for triple band characteristics and inserted two stub in the top of the rectangular ring patch to enhance impedance bandwidth characteristics. The proposed antenna has $18.0mm(2W_1+W_2){\times}33.0mm(L_7+L_8+L_9)$ on a dielectric substrate of $27.0mm(W_1){\times}44mm(L_1){\times}1.0mm$ size. From the fabrication and measurement results, impedance bandwidths of 660MHz (2,08 to 2.74GHz) for 2.4/2.5MHz band, 488MHz (3.40 to 3.88GHz) for 3.5MHz band, and 2,180MHz (4.61 to 6.79GHz) for 5,000MHz band were obtained based on the impedance bandwidth. The proposed antenna also obtained the measured gain and radiation pattern in the anechoic chamber.