• Title/Summary/Keyword: gadolinium

검색결과 325건 처리시간 0.02초

가돌리늄조영제가 이중에너지 X-선 흡수법을 이용한 골밀도검사에 미치는 영향 (Effects of Gadolinium Contrast agent on Bone Mineral Density Measurement using Dual Energy X-ray Absorptiometry)

  • 이근옥;이민수
    • 한국방사선학회논문지
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    • 제15권1호
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    • pp.63-70
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    • 2021
  • 골밀도검사에서 측정값에 영향을 주는 요인 중 하나인 방사선 조영제는 진단 목적으로 사용되어 조직 등에 흡수되어 골밀도 측정값을 높이는 효과가 있어, 골밀도검사 시행 전에는 될 수 있으면 피하고 있다. 이러한 방사선 조영제와는 다른 물리적 특성과 작용기전을 갖는 MRI 조영제는 금속원소인 가돌리늄 기반으로 방사선 불투과성 특징을 가지고 있어 일반적으로 방사선을 이용한 검사 전에 MRI 검사를 선 시행하고 있다. 본 연구에서는 MRI 조영제가 이중에너지 X-선 흡수법을 이용한 골밀도검사에 미치는 영향을 알아보고자 하였다. 가돌리늄 기반의 MRI 조영제 2종을 아크릴 수조에 용량별로 주입하여 인체모형 척추 팬텀을 넣고, 각 주입량 종류별로 5회씩 총 30회 scan 하여 L1-L4 번까지의 골밀도와 T-score를 분석하였다. 측정된 2종의 조영제별 Total(L1-L4) 골밀도의 평균값은 가도테레이트 메글루민성분 0mL, 7.5mL, 15mL일때, 각각 0.952±0.052, 0.957±0.050, 0.956±0.05 g/㎠로 나타났으며, 가도부트롤성분 0mL, 5mL, 10mL일 때, 각각 0.953±0.001, 0.954±0.001, 0.945±0.001g/㎠로 모든 부위에서 통계적으로 유의한 차이는 없었다(p>0.05). Total (L1-L4) T-score의 평균값은 가도테레이트 메글루민성분은 0mL, 7.5mL, 15mL일 때, 각각 -0.46±0.05, -0.4±0, -0.42±0.04로 나타났으며, 가도부트롤성분 0mL, 5mL, 10mL일 때, 각각 -0.46±0.05, -0.46±0.05, 0.5±0.00으로 모든 부위에서 통계적으로 유의한 차이는 없었다(p>0.05). 본 실험에서는 MRI 조영제는 이중에너지 X-선 흡수법을 이용한 골밀도검사에 영향이 없는 것으로 나타났으나, 임상 대상이 아닌 제한적 조건의 인체 모형 팬텀을 사용하여 조영제의 배출시간에 영향을 주는 신장 기능, 신체 상태 등이 고려되지 못한 제한점이 있어 추후 추가적인 임상연구 진행이 필요할 것으로 사료된다.

고주파 마그네트론 스퍼터법에 의해 제조된 Yttrium Iron Garnet 박막의 미세구조 및 자기적 특성 (Microstructure and Magnetic Characteristics of Yttrium Iron Garnet Thin Films Prepared by RF Magnetron Sputter)

  • 박명범;김병진;조남희
    • 한국세라믹학회지
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    • 제36권3호
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    • pp.293-300
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    • 1999
  • 고주파 마그네트론 스퍼터법을 이용한 YIG(yttrium iron garnet)박막 제조시 기판유형, 기판온도, 스퍼터전력, 스퍼터가스 등의 증착변수와 증착후 열처리 조건이 YIG 박막의 결정성, 화학조성, 미세구조 그리고 자기적 특성에 미치는 영향에 대하여 고찰하였다. 75$0^{\circ}C$ 이상의 온도에서 수행한 증착후 열처리에 의하여 비정질 박막이 결정화되었으며, 특히 GGG(gadolinium gallium garnet)기판 위에 제조된 박막은 강한 (111)우선배향성을 나타냈다. 박막조성은 스퍼터가스 내의 산소분율에 민감하게 영향을 받았으며, 산소분율이 20%인 스퍼터가스를 사용하여 제조된 박막은 Y2.88Fe3.84O12의 조성을 나타내었다. 증착후 열처리 온도가 90$0^{\circ}C$로부터 110$0^{\circ}C$로 증가함에 따라, GGG 기판위의 박막의 표면거칠기는 2.5nm에서 40nm로 증가하였으며, 보자력과 강자성 공명 선폭은 감소하였다.

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가우스형 에바네슨트파의 광압에 의한 Mie 입자 결합체들의 회전 (Optically induced rotation of combined Mie particles within an evanescent field of a gaussian beam)

  • 송영곤
    • 한국광학회지
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    • 제10권1호
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    • pp.5-9
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    • 1999
  • 파장이 532nm인 선형 파극된 Nd:YAG 레이저 광속을 Gadolimium Gallium Garnet 프리즘 면에서 전반시킬 때 형성된 에바네슨트파 석에 위차한 Mie 입자 결합체들이 광압에 의해 회전하는 것을 관찰하였다. 가우스 광속에 의한 에바슨트파의 최대 강도 지점에서 벗어난 곳에 위치한 3~5$\mu\textrm{m}$ 크기의 라텍스 또는 효모 결합체들이 0.1~1 rpm의 속도로 회전하엿는데, 두입자의 결합체는 광속의 진행 방향과 나란해질 때 회전이 멈추었으나 세입자 이상의 결합체들은 계속 회전하는 것을 볼 수 있었다. 본 실험 결과는 근접장 영역에서 에바네슨트파의 광압에 의한 마이크로 모터의 제작 가능성을 보여준다.

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Design on SDS2 On-line Poison Concentration Monitoring in CANDU

  • Kim, Seog-Nam;Jung, Ho-Chang;Kim, Sung;Kim, Ji-Hyeon;Han, Sang-Joon
    • Nuclear Engineering and Technology
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    • 제28권5호
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    • pp.500-505
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    • 1996
  • At the reference plant(Wolsong unit No. 1) a manual poison sampling system is provided to periodically sample gadolinium from each tank and analyze it in the laboratory to provide assurance that adequate poison concentration in each tank is maintained. The AECB required a continuous, on-line monitoring system. On Wolsong unit No. 2, process piping adapter and new instrument loops added to the Liquid Injection Shutdown System(LISS) which is part of SDS2. The new instrument loops continuously monitor SDS2 poison conductivity and initiate an alarm when the poison concentration is too low.

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Epidermoid Cyst Arising from the Corpus Callosum

  • Kim, Dok-Ryong;Kang, Hee-In;Kim, Jae-Hoon;Kim, Joo-Seung
    • Journal of Korean Neurosurgical Society
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    • 제41권3호
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    • pp.177-179
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    • 2007
  • Most of intradural epidermoid cyst arise as slowly growing extraaxial lesions but purely intracerebral epidermoid cysts are rare. A 39-year-old female presented with a headache during several months. Brain computed tomography [CT] scan showed a mass lesion in the both frontal lobe with heterogenous density approximately $5{\times}5cm$ in size. Magnetic resonance imaging [MRI] revealed a mass of heterogenous signal intensity on T1, T2-weighted image and faint enhancement with gadolinium [Gd]. Through the both interhemispheric approach, mass was removed subtotally except the calcified portion tightly attached to the corpus callosum. The patient discharged without neurological deficit. The authors report a case of epidermoid cyst in the corpus callosum and discuss the pathogenesis of the intraparenchymal epidermoid cyst.

Glioblastoma Mimicking Herpes Simplex Encephalitis

  • Nam, Tai-Seung;Choi, Kang-Ho;Kim, Myeong-Kyu;Cho, Ki-Hyun
    • Journal of Korean Neurosurgical Society
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    • 제50권2호
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    • pp.119-122
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    • 2011
  • We report a case of 70-year-old man with glioblastoma presenting as acute encephalitic illness. The patient exhibited sudden onset of cognitive impairment and headache for 2 days. Initial brain MRI showed left temporal lobe hyperintensity, and cerebrospinal fluid cytology revealed a mild pleocytosis. The patient had initially improved after medical treatment with a presumptive diagnosis of herpes simplex encephalitis (HSE). After 8 months, the patient complained of recurrent seizures. A follow-up brain MRI revealed marked increases in size and surrounding perilesional edema in the left temporal lesion on T2-weighted images and a new contrast-enhancing lesion on gadolinium-enhanced T1-weighted images. Stereotactic brain biopsy revealed a glioblastoma. The atypical encephalitic presentation of glioblastoma should be considered if definitive evidence for the diagnosis of HSE cannot be obtained.

Totally Ossified Metaplastic Spinal Meningioma

  • Ju, Chang Il;Hida, Kazutoshi;Yamauchi, Tomohiro;Houkin, Kiyohiro
    • Journal of Korean Neurosurgical Society
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    • 제54권3호
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    • pp.257-260
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    • 2013
  • A 61-year-old woman with a very rare case of totally ossified large thoracic spinal metaplastic meningioma, showing progressing myelopathy is presented. Computed tomographic images showed a large totally ossfied intradural round mass occupying the spinal canal on T9-10 level. Magnetic resonance imaging revealed a large T9-10 intradural extramedullary mass that was hypointense to spinal cord on T1- and T2-weighted sequences, partial enhancement was apparent after Gadolinium administration. The spinal cord was severely compressed and displaced toward the right at the level of T9-10. Surgical removal of the tumor was successfully accomplished via the posterior midline approach and the histological diagnosis verified an ossified metaplastic meningioma. The clinical neurological symptoms of patient were improved postoperatively. In this article we discuss the surgical and pathological aspects of rare case of spinal totally ossified metaplastic meningioma.

Non-Dura Based Intaspinal Clear Cell Meningioma

  • Ko, Jun-Kyeung;Choi, Byung-Kwan;Cho, Won-Ho;Choi, Chang-Hwa
    • Journal of Korean Neurosurgical Society
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    • 제49권1호
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    • pp.71-74
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    • 2011
  • A 34-year-old female patient was presented with leg and hip pain for 6 months as well as voiding difficulty for 1 year. Magnetic resonance imaging revealed a well-demarcated mass lesion at L2-3. The mass was hypo-intense on T1- and T2-weighted images with homogeneous gadolinium enhancement. Surgery was performed with the presumptive diagnosis of intradural extramedullary meningioma. Complete tumor removal was possible due to lack of dural adhesion of the tumor. Histologic diagnosis was clear cell meningioma, a rare and newly included World Health Organization classification of meningioma usually affecting younger patients. During postoperative 2 years, the patient has shown no evidence of recurrence. We report a rare case of cauda equina clear cell meningioma without any dural attachment.

A Case of Pineal Ependymoma

  • Hyun, Seung-Jae;Park, Seung-Won;Nam, Taek-Kyun;Hwang, Sung-Nam
    • Journal of Korean Neurosurgical Society
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    • 제42권1호
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    • pp.56-58
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    • 2007
  • A 64-year-old man was admitted to our hospital in semicomatous consciousness. Brain computed tomography scans demonstrated $2.6{\times}2.5\;cm$ sized hyperdense mass in the pineal region with multiple punctate calcifications and hydrocephalus. Brain magnetic resonance imaging demonstrated a pineal mass which was heterogeneously enhanced with gadolinium. After external ventricular drainage, the patient regained consciousness. The mass was totally removed via occipital transtentorial approach. No consequent ventricular shunt was needed and the patient recovered without any neurological deficit. Final pathologic report of the tumor was ependymoma.

Olfactory Schwannoma-Case Report-

  • Choi, Yu-Seok;Sung, Kyung-Su;Song, Young-Jin;Kim, Hyung-Dong
    • Journal of Korean Neurosurgical Society
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    • 제45권2호
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    • pp.103-106
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    • 2009
  • Intracranial schwannomas preferentially arise from the vestibular branch of the eighth nerve, and rarely from the trigeminal nerve, facial nerve, and lower cranial nerves. Anterior cranial fossa schwannomas are extremely uncommon and few details about them have been reported. The patient was a 39-year-old woman whose chief complaints were anosmia and frontal headache for 2 years. The gadolinium (Gd)-enhanced magnetic resonance imaging (MRI) showed an extra-axial mass from ethmoid sinus to right frontal base region near the midline, with solid enhancement in lower portion and multicystic formation in upper portion. The tumor was totally resected via basal subfrontal approach. At operation, the tumor had cystic portion with marginal calcification and the anterior skull base was destructed by the tumor. The olfactory bulb was involved, and the tumor capsule did not contain neoplastic cells. The histopathological diagnosis was schwannoma. We report a rare case of anterior cranial fossa schwannoma with literature review.