• Journal of the Economic Geographical Society of Korea
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• v.16 no.4
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• pp.551-566
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• 2013

This study aims to evaluate the industrial cluster policy implemented in Korea during the last decade or so, examine whether it can still be a valid policy measure in the creative economy regime, and propose policy directions for the future. It is evaluated that the cluster policy has contributed to increasing productivity by improving networks between companies, universities and research centers and thus strengthening innovation infrastructure. The policy, however, by its characteristics of government-domination, failed to develop open-ended and flexible spontaneous clusters. Industrial clusters have the capability to contribute to the virtuous circle of creative economy by enhancing creativity and innovativeness, and subsequently by increasing value-added. In order to maximize these positive effects, a few suggestions are made, including being faithful to the very nature of clusters, e.g. geographical proximity and connectedness, intending clusters with creativity well maintained, orienting toward multi-scalar clusters with a mixture of local and global perspectives, and matching regional and industrial policies with regards to clusters.

• Journal of the Korean GEO-environmental Society
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• v.15 no.6
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• pp.75-83
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• 2014

Suction bucket foundation is installed with the differential pressure created by pumping water out of bucket. Bucket foundation has usually been utilized in mooring anchor for offshore platform or floating oil and gas production facilities in the open sea. After suction bucket foundation successfully was applied as the foundation for offshore wind turbines in Europe, it recently attracts much attention in Korea, too. To estimate the penetration resistance of the suction bucket foundation is one of the important matters that should be considered during its installation. This study carried out a series of model tests to investigate the penetration resistance of suction bucket foundation. And the mobilized soil strength factor was reviewed through comparing the experimental results by two installation ways (e.g., push-in-load and suction) and the results calculated by the conventional equation.

• Journal of Environmental Health Sciences
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• v.36 no.3
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• pp.191-198
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• 2010

The aim of this study was to determine the concentrations of air-borne microorganisms (bacteria, fungi, gram negative bacteria (GNB), endotoxins, and respirable suspended particles (RSPs), and their correlation with environmental parameters (temperature, humidity, and carbon dioxide levels) in duck houses. The mean concentrations of bacteria, fungi, and GNB were very high (> $10^6\;CFU/m^3$), and endotoxin levels exceeded $10^3\;EU/m^3$. Among the various work stages, in the task of receiving ducks, bacteria were $6.2{\times}10^6;CFU/m^3$, and GNB were $5.4{\times}10^6\;CFU/m^3$, while RSPs levels were $397.6\;{\mu}g/m^3$ and endotoxin levels were $47.2{\times}10^3\;EU/m^3$ in the task of dividing the ducks, and fungi were $4.9{\times}10^6\;CFU/m^3$ in the task of shipping the ducks. The concentrations of RSPs and endotoxins were significantly higher in tasks involving greater movement of ducks in the house, relative to tasks involving little movement of ducks (p<0.05). Further, with progression in growth of the ducks, the concentrations of bacteria, GNB, endotoxins, and RSPs were significantly increased. There was significant correlation between levels of GNB with bacteria (r=0.75) and fungi (r=0.86), endotoxins with RSPs (r=0.75), bacteria with fungi (r=0.39), and carbon dioxide with RSPs (r=0.38), bacteria (r=0.33), and endotoxins (r=0.31). These results suggest considerable respiratory hazard for farmers in these environments.

• Computers and Concrete
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• v.2 no.6
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• pp.423-437
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• 2005

In this study two single-bay, three-storey space frames, one with brick masonry infill in the second and third floors representing a soft-storey frame and the other without infill were designed and their 1:3 scale models were constructed according to non-seismic detailing and the similitude law. The models were excited with an intensity of earthquake motion as specified in the form of response spectrum in Indian seismic code IS 1893-2002 using a shake table. The seismic responses of the soft-storey frame such as fundamental frequency, mode shape, base shear and stiffness were compared with that of the bare frame. It was observed that the presence of open ground floor in the soft-storey infilled frame reduced the natural frequency by 30%. The shear demand in the soft-storey frame was found to be more than two and a half times greater than that in the bare frame. From the mode shape it was found that, the bare frame vibrated in the flexure mode whereas the soft-storey frame vibrated in the shear mode. The frames were tested to failure and the damaged soft-storey frame was retrofitted with concrete jacketing and, subjected to same earthquake motions as the original frames. Pushover analysis was carried out using the software package SAP 2000 to validate the test results. The performance point was obtained for all the frames under study, therefore the frames were found to be adequate for gravity loads and moderate earthquakes. It was concluded that the global nonlinear seismic response of reinforced concrete frames with masonry infill can be adequately simulated using static nonlinear pushover analysis.

• Smart Structures and Systems
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• v.8 no.2
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• pp.173-190
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• 2011

As a practical and effective seismic resisting technology, the base isolation system has seen extensive applications in buildings and bridges. However, a few problems associated with conventional lead-rubber bearings have been identified after historical strong earthquakes, e.g., excessive permanent deformations of bearings and potential unseating of bridge decks. Recently the applications of shape memory alloys (SMA) have received growing interest in the area of seismic response mitigation. As a result, a variety of SMA-based base isolators have been developed. These novel isolators often lead to minimal permanent deformations due to the self-centering feature of SMA materials. However, a rational design approach is still missing because of the fact that conventional design method cannot be directly applied to these novel devices. In light of this limitation, a displacement-based design approach for highway bridges with SMA isolators is proposed in this paper. Nonlinear response spectra, derived from typical hysteretic models for SMA, are employed in the design procedure. SMA isolators and bridge piers are designed according to the prescribed performance objectives. A prototype reinforced concrete (RC) highway bridge is designed using the proposed design approach. Nonlinear dynamic analyses for different seismic intensity levels are carried out using a computer program called "OpenSees". The efficacy of the displacement-based design approach is validated by numerical simulations. Results indicate that a properly designed RC highway bridge with novel SMA isolators may achieve minor damage and minimal residual deformations under frequent and rare earthquakes. Nonlinear static analysis is also carried out to investigate the failure mechanism and the self-centering ability of the designed highway bridge.

• Imaging Science in Dentistry
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• v.45 no.3
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• pp.187-192
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• 2015

Cleidocranial dysplasia (CCD) is a rare congenital disorder, typically characterized by persistently open skull sutures, aplastic or hypoplastic clavicles, and supernumerary teeth. Mutations in the gene encoding the runt-related transcription factor 2 (RUNX2) protein are responsible for approximately two thirds of CCD patients. We report a 20-year-old CCD patient presenting not only with typical skeletal changes, but also complex dental anomalies. A previously undiagnosed odontoma, 14 supernumerary teeth, a cystic lesion, and previously unreported fused primary teeth were discovered on cone-beam computed tomography (CBCT) scans. Mutation analysis identified the causal c.578G>A (p.R193Q) mutation in the RUNX2 gene. At 20 years of age, the patient had already missed the optimal period for dental intervention. This report describes the complex dental anomalies in a belatedly diagnosed CCD patient, and emphasizes the significance of CBCT assessment for the detection of dental anomalies and the importance of early treatment to achieve good outcomes.

• Annals of Clinical Neurophysiology
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• v.17 no.2
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• pp.68-72
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• 2015

Background: The effects of omega-3 polyunsaturated fatty acids (PUFAs) on cerebral vessels have not been clarified until now. Thus we investigated the efficacy of omega-3 PUFAs supplementation on cerebral blood flow velocity and vascular resistance via transcranial doppler (TCD). Methods: Consecutive twenty patients (13 male and 7 female) with at least 1 cerebrovascular risk factor or a known cerebrovascular disease were enrolled. Patients were treated with omega-3 PUFAs (1 g, two times per day) for 12 weeks. Cerebral blood flow velocity, resistance index, and pulsatile index were checked before and after 12 weeks of treatment using TCD. Results: The change of resistance index in right MCA (from $0.58{\pm}0.07$ to $0.55{\pm}0.07$, p = 0.042) and left PCA (from $0.56{\pm}0.07$ to $0.53{\pm}0.06$, p = 0.037) showed significant improvement after 12 weeks of omega-3 PUFAs treatment. The changes in other vessels, however, failed to show any significant changes compared to the baseline. Conclusions: Omega-3 PUFAs treatment showed feasible efficacies for cerebral vascular resistances in this open label trial. To confirm these results, larger samples of patients and longer period of follow-up is warranted.

• Journal of the Korean Solar Energy Society
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• v.22 no.3
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• pp.47-56
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• 2002

The office is an excellent candidate for implementing daylighting techniques because of the relatively high electric lighting power densities and long daytime use pattern. The quantity of light available for a space can be translated in term of the amount of energy savings through a process of a building energy simulation. To get significant energy savings in general illumination, the electric lighting system must be incorporated with a daylight - activated dimmer control. A prototype configuration of an office interior has been established and the integration between the building envelope and lighting and HVAC systems is evaluated based on computer modeling of a lighting control facility. First of all, an energy-efficient luminaire system is designed for both a totally open-plan office interior and a partitioned office. A lighting design and analysis program, Lumen-Micro 2000 predicts the optimal layout of a conventional fluorescent lighting fixture to meet the designed lighting level and calculates unit power density, which translates the demanded amount of electric lighting energy. A dimming control system integrated with the contribution of daylighting has been applied to the operating of the artificial lighting. Annual cooling load due to lighting and the projecting saving amount of cooling load due to daylighting under overcast diffuse sky are evaluated by a computer software, ENER-Win. In brief, the results from building energy simulation with measured daylight illumination levels and the performance of lighting control system indicate that daylighting can save over 70 percent of the required energy for general illumination in the perimeter zones through the year. A 25 % of electric energy for cooling may be saved by dimming and turning off the luminaires in the perimeter zones.

• Journal of Microbiology
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• v.38 no.2
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• pp.80-87
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• 2000

The nucleotide sequence of the luxC gene coding for lux-specific fatty acyl-CoA reductase and the upstream DNA (325bp)of the structural gene from bioluminescent bacterium, Photobacterium phosphoreum, has been deternubed. An open reading frame extending for more than 20 codons in 325 bp DNA upstream of luxC was not present in both directions. The lux gene can be translated into a polypeptide of 54 kDa and the amino acid sequences of lux specific reductases of P. phosphoreum shares 80, 65, 58, and 62% identity with those of the Photobacterium leiognathi, Vibrio fischeri, Vibrio harveyi, and Xehnorhabdus luminescenens reductases, respectively. Analyses of codon usage, showing that a high frequency (2.3%) of the isoleucine codon, AUA, in the luxC gene compared to that found in Escherichia coli genes (0.2%) and its absence in the luxA and B genes, suggested that the AUA codon may play a modulator role in the expression of lux gene in E. coli. The structural genes (luxC, D, A, B, E) of the P. phosphoreum coding for luciferase (${\alpha}$,${\beta}$) and fatty acid reductase (r, s, t) polypeptides can be expressed exclusively in E. coli under the T7 phage RNA polymerase/promoter system and identificationof the [35S]methionine labelled polypeptide products. The degree of expression of lux genes in analyses of codon usage. High expression of the luxC gene could only be accomplished in a mutant E. coli 43R. Even in crude extracts, the acylated acyl-CoA reductase intermediate as well as acyl-CoA reductrase activities could be readily detected.

• Carbon letters
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• v.4 no.1
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• pp.1-9
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• 2003

Recently, the control of pore-characteristics of nano-porous materials has been studied extensively because of their unique applications, which includes size-selective separation, gas adsorption/storage, heterogeneous catalysis, etc. The most widely adopted techniques for controlling pore characteristics include the utilization of pillar effect by metal oxide and of templates such as zeolites. More recently, coordination polymers constructed by transition metal ions and bridging organic ligands have afforded new types of nano-porous materials, porous metal-organic framework(porous MOF), with high degree and uniformity of porosity. The pore characteristics of these porous MOFs can be designed by controlling the coordination number and geometry of selected metal, e.g transition metal and rare-earth metal, and the size, rigidity, and coordination site of ligand. The synthesis of porous MOF by the assembly of metal ions with di-, tri-, and poly-topic N-bound organic linkers such as 4,4'-bipyridine(BPY) or multidentate linkers such as carboxylates, which allow for the formation of more rigid frameworks due to their ability to aggregate metal ions into M-O-C cluster, have been reported. Other porous MOF from co-ligand system or the ligand with both C-O and C-N type linkage can afford to control the shape and size of pores. Furthermore, for the rigidity and thermal stability of porous MOF, ring-type ligand such as porphyrin derivatives and ligands with ability of secondary bonding such as hydrogen and ionic bonding have been studied.