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Effects of Eurycoma longifolia Jack in Maintaining Mating Behavior of Sexually Experienced Castrated Male Rats

  • Ang, Hooi-Hoon;Cheang, Hung-Seong
    • Natural Product Sciences
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    • v.5 no.3
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    • pp.138-141
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    • 1999
  • The effects of Eurycoma longifolia Jack were studied in maintaining mating behavior of sexually experienced castrated male rats after dosing them with 500 mg/kg daily of E. longifolia Jack for 10 days prior to test and later continued for two weeks where the rats were then castrated. The similar dosage was then continued for 12 weeks post-castration. However, $400\;{\mu}g/day$ of testosterone was administered subcutaneously on the day of castration and lasted for 6 weeks post-castration but later raised to $800\;{\mu}g/day$ until 12 week post-castration. Tests were conducted weekly from 2-6 weeks and 8-12 weeks post-castration. Results showed that all the experimental male rats exhibited mating behavior before castration. Further results also indicated that E. longifolia Jack successfully maintained mating behavior but less than precastration level from 2-6 weeks and later increased from 8-12 weeks post-castration. Similarly, $400\;{\mu}g/day$ of testosterone was effective in maintaining mating behavior from 2-6 weeks post-castration. However, $800\;{\mu}g/day$ of testosterone managed to return the male rats to the precastration level with all male rats exhibited mating behavior from 8-12 weeks post-castration. Further results also indicated that testosterone significantly increased the penis weights (p < 0.05) as compared to the E. longifolia Jack. In conclusion, this study shows that E. longifolia Jack continued to maintain mating behavior of sexually experienced castrated male rats, giving further evidence of the folkuse of this plant as aphrodisiac.

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A Study on the Level of Medical Record Documentation and Agreement in the Information on the Patient's Past History (과거력 의무기록 정보의 기재정도 및 일치도 분석)

  • Seo, Jung-Sook;Yu, Seung-Hum;Oh, Hyohn-Joo;Kim, Yong-Oock
    • Korea Journal of Hospital Management
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    • v.13 no.1
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    • pp.42-64
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    • 2008
  • This study was conducted to evaluate the quality in medical records by analyzing its completeness through setting up the level of record on the patient's past history and through examining the actual medial records. Targeting the information on the patient's past history in interns' records, residents' records and nurses' records toward 403 inpatients who were admitted first in 2004 at an university hospital due to stomach cancer. We analyzed whether the charts were recorded or not, recording level, the satisfaction with the expectant level of the records in the hospital targeted for a research and the level of agreement. The results were as follows; first, as for the rate of recording those each items, they were high in the chief complaint & present illness and the past illness history. Depending on the group of recorders, the recording rate showed big difference by items. Second, as a result of measuring the level after dividing the recording level of items for the patient's past history from Level 1 to Level 4 by each item, the admission history, the past illness history, and the family history were about Level 3, and the smoking history, the medication history, the chief complaint & present illness, the drinking history and allergy were about Level 2. In the admission department, it was excellent in the interns' records for the medical department. Third, as a result of its satisfactory level by comparing the expect level of a record and the actual record by item in information on the patient's past history, which was expected by the medical-record committee members of the hospital targeted for a study. And forth, we analyzed the level of agreement with Kappa score in the level of 'Yes' or 'None' related to the corresponding matter in Level 1, in terms of information on the past history in the intern's record, the resident's record, and the nurse's record. The level of agreement in the resident's record & the nurse's record, and in the intern's record & the resident's record was from "excellent" to "a little good". There were differences in the level of completeness and in reliability for the information on the past history by the recorder group or by the admission department. The encounter process that was performed by the admission department or the recorder group, indicated the result that was directly reflected on the quality of medical records, thus it was required further study about the medical record documentation process and quality of care. The items that showed the high recording rate quantitatively were rather low, consequently we'd should develop the tool for the qualitative inspection and evaluate the medical records further. And the items were needed to be detailed in the record level were rather low, and hence there needed to be a documentation guideline and education by the clinical departments.

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A proposed cultural competence training program for nurses based on their transcultural self-efficacy

  • Jin, Ju-hyun;Cleofas, Jerome V.
    • International Journal of Advanced Culture Technology
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    • v.6 no.2
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    • pp.86-99
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    • 2018
  • This study examined the relationship between the demographic profiles of 260 staff nurses in the SPC Health Care Ministry Hospitals and their Transcultural Self-Efficacy (TSE) level on the Cognitive, Practical and Affective dimensions. To obtain the result, among the nine (9) demographic profile items, three (3) common positive predictors were considered, namely, 1) Educational attainment level; 2) Age; and 3) Willingness to work abroad in all three dimensions. While in the Practical and Affective dimensions, the number of years employed were a common negative predictor and in the Affective dimension, Gender of participants was added as the positive predictor. Therefore, there are some significant demographic characteristics of respondents influence to the transcultural self-efficacy. Further, based on the results of this diagnostic study, the researcher designed the One (1) year Cultural Competence Training Program for staff nurses. For future research, the researcher recommended to conduct a further study that will evaluate the effectiveness of the educational intervention by approaching a longitudinal study form administering the test and retest of TSET.

Development and Implementation of Multi-source Remote Sensing Imagery Fusion Based on PCI Geomatica

  • Yu, ZENG;Jixian, ZHANG;Qin, YAN;Pinglin, QIAO
    • Proceedings of the KSRS Conference
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    • 2003.11a
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    • pp.1334-1336
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    • 2003
  • On the basis of comprehensive analysis and summarization of the image fusion algorithms provided by PCI Geomatica software, deficiencies in image fusion processing functions of this software are put forwarded in this paper. This limitation could be improved by further developing PCI Geomatica on the user’ side. Five effective algorithms could be added into PCI Geomatica. In this paper, the detailed description of how to customize and further develop PCI Geomatica by using Microsoft Visual C++ 6.0, PCI SDK Kit and GDB technique is also given. Through this way, the remote sensing imagery fusion functions of PCI Geomatica software can be extended.

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High School Students' Preferences of Concrete and Formal Operational Levels of Instructions in CAI (구체적 조작수준과 형식적 조작수준의 CAI 형태에 대한 학생의 선호경향)

  • Kim, Young-Soo
    • Journal of The Korean Association For Science Education
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    • v.6 no.2
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    • pp.9-13
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    • 1986
  • This study was designed to investigate students' preferences of instructional modes in CAI which have concrete of formal operational level instructions. Thirty five students of the high school in America were assessed using Longeot test and were given CAI material on the Apple II e computer. The results of this study showed that students who were only capable of functioning at the concrete level of operations frequently preferred to attempt formal operational level instructions for which they were not capable of success. Further, formal operational students frequently preferred concrete operational instructions. There was also no significant difference in the selection of formal operational level of instructions between concrete and formal operational students. There was also no significant correlation between the number of selected formal operational level instructions and the Longeot test score. These results suggested the student's preference to a cognitive developmental level of instruction in CAI was independent of his or her cognitive developmental level.

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Multi-level Product Information Modeling for Managing Long-term Life-cycle Product Information (수명주기가 긴 제품의 설계정보관리를 위한 다층 제품정보 모델링 방안)

  • Lee, Jae-Hyun;Suh, Hyo-Won
    • Korean Journal of Computational Design and Engineering
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    • v.17 no.4
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    • pp.234-245
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    • 2012
  • This paper proposes a multi-level product modeling framework for long-term lifecycle products. The framework can help engineers to define product models and relate them to physical instances. The framework is defined in three levels; data, design model, modeling language. The data level represents real-world products, The model level describes design models of real-world products. The modeling language level defines concepts and relationships to describe product design models. The concepts and relationships in the modeling language level enable engineers to express the semantics of product models in an engineering-friendly way. The interactions between these three levels are explained to show how the framework can manage long-term lifecycle product information. A prototype system is provided for further understanding of the framework.

Effects of KakamGoBonHwan (KGBH) on Inhibition of Impairment of Learning and Memory, and Acetylcholinesterase in Amnesia mice (가감고본환(加減固本丸)이 치매병태모델에 미치는 영향(影響))

  • Jung, In-Cheol;Lee, Sang-Ryong;Ha, Su-Young
    • Journal of Oriental Neuropsychiatry
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    • v.13 no.1
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    • pp.53-77
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    • 2002
  • Alzheimer's disease(AD) is a progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APPs) overexpression. The present research is to examine the inhibitory effect of KGBH on PS1, PS2 and APPs overexpression detected by Western blotting. To verify the Effects of KGBH on cognitive deficits further, we tested it on the scopolamine(1mg/kg)-induced amnesia model of the mice using the Morris water maze tests, and there were ameliorative effects on memory impairment as a protection against scopolamine. KGBH only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, where as blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracellular serum level. In conclusion, studies of KGBH that has been known as anti-choline and inhibitory ablilities of APPs overexpression, could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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Effects of Morinda officinalis (MDOF) on Inhibition of Impairment of Learning and Memory, and Acetylcholinesterase in Amnesia Mice (파극천(巴戟天)이 치매병태모델에 미치는 영향(影響))

  • Jung, In-Chul;Lee, Sang-Ryong;Kim, Hyun-Soo
    • Journal of Oriental Neuropsychiatry
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    • v.14 no.1
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    • pp.45-58
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    • 2003
  • Alzheimer's disease(AD) is progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APP) overexpression. The present research is to examine the inhibition effect of MDOF on PS-1, PS-2 and APP overexpression by detected to Western blotting. To verify the effects of MDOF on cognitive deficits further, we tested it on the scopolamine-induced amnesia model of the mice using the Morris water maze tests, and there was ameliorative effects of memory impairment as a protection to scopolamine. MDOF only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracelluar serum level compared with only scopolamine injection. In conclusion, studies of MDOF that has been know as anti-choline and inhibition ablilities of APP overexpression, this could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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Effects of Cyperus rotundus (CPRT) on Inhibition of Impairment of Learning and Memory, and Acetylcholinesterase in Amnesia Mice (향부자(香附子)가 치매병태모델에 미치는 영향(影響))

  • Jung, In-Chul;Lee, Sang-Ryong;Yun, Sang-Hak
    • Journal of Oriental Neuropsychiatry
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    • v.14 no.1
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    • pp.59-74
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    • 2003
  • Alzheimer's disease(AD) is a progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APP) overexpression. The present research is to examine the inhibition effect of CPRT on PS-1, PS-2 and APP overexpression by detected to Western blotting. To verify the Effects of CPRT on cognitive deficits further, we tested it on the scopolamine-induced amnesia model of the mice using the Morris water maze tests, and there was ameliorative effects of memory impairment as a protection to scopolamine. CPRT only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and inreased extracellular serum level compared with only scopolamine injection. In conclusion, studies of CPRT that has been known as anti-choline and inhibition ablilities of APP overexpression, this could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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Effects of ChenWhangBosimDan(CWBD) on Inhibition of Impairment of Learning and Memory, and Acetylcholinesterase in Amnesia mice (천왕보심단(天王補心丹)이 치매병태모델에 마치는 영향(影響))

  • Jung, In-Chul;Lee, Sang-Ryong;Lee, Jun-Young
    • Journal of Oriental Neuropsychiatry
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    • v.13 no.2
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    • pp.149-171
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    • 2002
  • Alzheimer's disease(AD) is a progressive neurodegenerative disease, which is pathologically characterized by neuritic plaques and neurofibrillary tangles associated with the acetylcholinesterase, apolipoprotein E and butylcholinesterase, and by mutations in the presenilin genes PS1 and PS2, and amyloid precursor proteins (APPs)'s overexpression. The present research is to examine the inhibitory effect of CWBD on PS1, PS2 and APPs's overexpression detected by Western blotting. To verify further the effects of CWBD on cognitive deficits, we tested it on the scopolamine(1mg/kg)-induced amnesia model of the mice using the Morris water maze tests, and there were ameliorative effects on memory impairment as a protection from scopolamine. CWBD only partially blocked the increase in blood serum level of acetylcholinesterase and Uric acid induced by scopolamine, whereas blood glucose level was shown to attenuate the amnesia induced by scopolamine and increased extracellular serum level. In conclusion, studies of CWBD that has been known as anti-choline and inhibitory ablilities of APPs's overexpression could also be used further as a important research data for a preventive and promising symptomatic treatment for Alzheimer's disease.

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