• 대한중풍순환신경학회지
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• 제9권1호
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• pp.1-7
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• 2008

Objectives : We questioned whether the tongue diagnosis is effective for judging seriousness of cerebrovascular accidents. This study is about the relationship between tongue diagnosis and National Institute of Health Stroke Scale(NIHSS) in acute stroke patients. Methods : 738 subjects were recruited from the patients admitted to the department of internal medicine at Kyung-Hee University oriental medical center, Kyung-Hee University East-West Neo Medical Center, Kyungwon university Incheon oriental medical center, Kyungwon university Songpa oriental medical center and DongGuk university Ilsan oriental medical center from April 2007 to August 2008. We looked at the tongue as in three dimensions of tongue color, tongue fur color and tongue body. And, we calculated NIHSS means according to the subtypes of three dimensions. Results : 1. In the Tongue color, from the most commom to least common colors were pale red, red, pale, bluish purple, and ect. The NIHSS mean score of red is significantly higher than pale and pale red. 2. In the Tongue fur color, white fur was the most common, and then yellow fur, etc. There is no significant difference among three subtypes in the NIHSS mean score. 3. In the Tongue body, etc. is the most common, followed by teeth-marked tongue, enlarged tongue, blood patchy tongue, and mirror tongue. The NIHSS mean score of teeth-marked tongue is significantly lower than blood patchy tongue and mirror tongue. Conclusions : The tongue color and the tongue body are useful indexes for judging seriousness of cerebrovascular accidents presented by NIHSS. But in our study, the tongue fur color was not useful. Further study is necessary on the tongue fur.

• Journal of Microbiology and Biotechnology
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• 제30권1호
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• pp.127-135
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• 2020

Small RNAs (sRNAs) are widespread and play major roles in regulation circuits in bacteria. Previously, we have demonstrated that transcription of esrE is under the control of its own promoter. However, the regulatory elements involved in EsrE sRNA expression are still unknown. In this study, we found that different cis-regulatory elements exist in the promoter region of esrE. We then screened and analyzed seven potential corresponding trans-regulatory elements by using pull-down assays based on DNA affinity chromatography. Among these candidate regulators, we investigated the relationship between the ferric uptake regulator (Fur) and the EsrE sRNA. Electrophoresis mobility shift assays (EMSAs) and β-galactosidase activity assays demonstrated that Fur can bind to the promoter region of esrE, and positively regulate EsrE sRNA expression in the presence of Fe²⁺.

• 자연과학논문집
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• 제18권1호
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• pp.47-53
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• 2007

바실러스 서브틸리스 유전체에서 여러 환경의 적응에 이용할 것으로 보이는 새로운 small RNA를 찾는 시도로 다음과 같은 방식으로 유전체를 검색하였다. 첫째로 유전자들 사이에 존재하는 DNA 서열을 대상으로 전사인자들인 PerR, OhrR, Fur, Zur의 인식서열을 조사하였고, 둘째로 인자 비의존성 전사종결 부위를 조사하였다. 이들 조사에서 전사인자의 위치와 전사종결부위가 300 bp 내외에서 가까이 존재하는 후보 DNA 서열을 대상으로 전사인자 부위에서 전사촉진자의 서열이 발견되는지를 조사하였다. 이 결과 PerR 5개, Fur 2개, OhrR, Zur에서 각각 1개의 새로운 small RNA로 추정되는 부위가 발견되었다.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2001년도 추계 학술발표회 논문집 Proceedings of EESK Conference-Fall 2001
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• pp.19-27
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• 2001

Seismic parameters fur computation of ground motions in Southern Korea are obtained from recently recorded data, and site-independent regional and site-dependent local strong ground motions are predicted using efficient computational techniques. For the computation of ground motions, we devised an efficient procedure to compute site-independent $x_{q}$ and dependent $x_{s}$ values separately. The first step of this procedure is to use the coda normalization method far computation of site independent Q or corresponding $x_{q}$ value. The next step is the computation of $x_{s}$, values fur each site separately using the given $x_{q}$ value. For computation of ground motions the empirical Green's function (EGF) is modified to account fur the depth and distance variations of subevents on a finite fault plane using the theoritical Green's function. It is computed using wavenumber integration technique in layered media. The site dependent ground motions at seismic stations in southeastern local area were properly simulated using the modified empirical Green's function method in layered medium. The proposed method and procedures fur estimation of site dependent seismic parameters and ground motions could be efficiently used in the low and moderate seismicity regions.ons.s.ons.

• Journal of Korean Biological Nursing Science
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• 제8권1호
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• pp.39-48
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• 2006

Purpose: To see the effects of capsaicin on the peripheral nerve damage of intervibrissal fur in mature rats, Method: 24 female mature rats($200{\sim}250g$) are divided to 3 groups and compared with each other. Immunofluorescence dye using CGRP and PGP antibodies was performed and 8 weeks after administration of capsaicin with control group. Result: The immunopositive reaction against PGP and CGRP was reduced by the damage of epidermal and dermal endings in unmyelinated sheath and thin myelinated sheath and the group after 8weeks showed distinct positive reaction of PGP and CGRP than the group after 4 weeks which means the recover of nerves. Conclusion: As a result, capsaicin influenced on pain-related neurotransmitter like CGRP when administerd to mature rats and even though it caused the damages on unmyelinated sheath and thin myelinated sheath, the damaged nerves recovered after 8 weeks. Also the research about sensory nerve endings scattered over middle dermal and deep epidermal layers such as lanceolate, merkel reticular, Ruffini endings should be studied when the research of the inner conical body is performed. Further studies are necessary about the toxicity and effect of capsaicin on the peripheral nerve endings.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 추계학술대회 논문집
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• pp.703-708
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• 2002

An elastomeric bushing is a device used in automotive suspension systems to reduce the load transmitted from the wheel to the frame of the vehicle. A bushing is an elastomeric hollow cylinder which is bonded to a solid steel shaft at its inner surface and a steel sleeve at its outer surface. The relation between the load applied to the shaft or sleeve and the relative deformation of Elastomeric bushing is nonlinear and exhibits features of viscoelasticity. A load-displacement relation fur elastomeric bushing is important fur dynamic numerical simulations. A boundary value problem for the bushing response leads to the load-displacement relation which requires complex calculations and is hence unsuitable. Therefore, by modifying the constitutive equation for a nonlinear viscoelastic incompressible material developed by Lianis, the data fur the elastomeric bushing material was obtained and this data was used to derive the new load-displacement relation fur radial response of the bushing. After the load relaxation function for the bushing is obtained from the step displacement control test, Pipkin-Rogers model was developed. Solutions were allowed for comparison between the results of Modified Lianis model and those of the proposed model. It is shown that the proposed Pipkin-Rogers model is in very good agreement with Modified Lianis model.

• 한국의류학회지
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• 제48권4호
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• pp.597-614
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• 2024

This study examines how idealism and relativism, which are the two dimensions of personal moral philosophy, and the perceived moral intensity affect the purchase behavior of consumers regarding fashion items made of animal skin and fur. Data were collected through an online survey, and data from 372 Korean female consumers were statistically analyzed, excluding questionnaires with non-response, insincere responses, and outliers. The data analysis using structural equation models showed a significant effect of idealism but a non-significant effect of relativism on perceived moral intensity concerning the purchase of real leather and fur fashion items. In a structural equation model for each fashion item, perceived moral intensity had a negative effect on purchase behavior. The indirect effect of idealism on purchase behavior through the perceived moral intensity was confirmed to be statistifically significant for each fashion item. However, neither idealism nor relativism had a direct effect on the purchase behavior of both fashion items. The research results were discussed from an academic perspective and practical implications were presented.

• Agricultural and Biosystems Engineering
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• 제3권2호
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• pp.73-78
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• 2002

Cabbage is one of the most important vegetable in Korea. The cabbage production was mainly based on human labor A comprehensive research fur substituting the human labor by machines has been performed until now. In general, cabbage is cultivated on hillside in Korea. Picking up the harvested cabbages in field and carrying to a vehicle fur transportation are very laborious work. Manual transportation of cabbage is likely to damage the quality and is also a cause to increase the cost of cabbage production. This study was to develop and evaluate a prototype cabbage loader fur efficient and safe transportation of cabbage. The developed loader was a semi-tracked vehicle operated by a hydraulic system, allowing the safe transportation and loading of cabbage in a steep field. The maximum loading weight of the loader was 1.0 ton. By using two sets of safety devices attached to the loader to avoid the roll-over in a steep field, the static rollover slopes were increased up to 34.0% and 37.4% fur the left and the rear direction, respectively The maximum field speed was about 6km/hr with two cabbage pallets of 750kg at a 25% inclined field. The loading capacity of the loader was about 35 pallets/hr when picking up, carrying, and unloading two cabbage pallets for one loading operation. The loading capacity was more than 8 times in comparison with the conventional human labor. The developed loader could be used fur loading and carrying the other vegetables. The study suggested a possible approach for designing the field machines operated on hillside.

• Mycobiology
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• 제29권3호
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• pp.164-169
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• 2001

A new medium for studies of diversity among populations of $A_1\;and\;A_2$ mating types of Phytophthora infestans has been evolved. The rye A agar and V-8 juice agar media on which P. infestans grows well have been amended with rhizome powder of Cyperus rotundus. A total of 259 isolates of $A_1\;and\;A_2$ mating types representing Japan, Korea, India, Taiwan, Indonesia, Thailand, China, Nepal, U.K and Medico were screened for their growth response on these two media. Most of the A1 isolates did not grow well on them except Thailand while growth of $A_2$ mating types differed as some grew on it whereas others did not. It is quite likely that the populations of $A_2$ mating types that did not grow well on rhizome-amended medium are of different clonal lineage. This suggests that this medium can be used for the study of diversification among the isolates of the same or both the mating types as well as to detect the newly introduced genetically different isolates of P. infestans in a locality where it was not reported earlier.

• Biomolecules & Therapeutics
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• 제25권3호
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• pp.315-320
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• 2017

We investigated the role of autophagy in SNUC5/5-FUR, 5-fluorouracil (5-FU) resistant SNUC5 colon cancer cells. SNUC5/5-FUR cells exhibited low level of autophagy, as determined by light microscopy, confocal microscopy, and flow cytometry following acridine orange staining, and the decreased level of GFP-LC3 puncta. In addition, expression of critical autophagic proteins such as Atg5, Beclin-1 and LC3-II and autophagic flux was diminished in SNUC5/5-FUR cells. Whereas production of reactive oxygen species (ROS) was significantly elevated in SNUC5/5-FUR cells, treatment with the ROS inhibitor N-acetyl cysteine further reduced the level of autophagy. Taken together, these results indicate that decreased autophagy is linked to 5-FU resistance in SNUC5 colon cancer cells.