• Title/Summary/Keyword: fundamental relation

Search Result 445, Processing Time 0.036 seconds

Effects of atopic dermatitis induced materials on the expression of cytokine genes in human monocytes and mast cells (인간의 단핵구와 비만세포에서 다양한 아토피 유발물질이 사이토카인 유전자의 발현에 미치는 영향)

  • Park, Koung-Suk;Kim, Kyung-Jun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
    • /
    • v.23 no.2
    • /
    • pp.41-56
    • /
    • 2010
  • Objectives : On an experimental basis, the effects of atopic dermatitis induced materials on the expression of cytokine genes in human monocytes (THP-1, U937) and mast cells were studied. This study was carried out to be considered a fundamental knowledge in the research on the good of oriental medicine. Methods : After culturing THP-1, U937, and HMC-1, with the three different concentrations of LPS ($1\;{\mu}g/ml$), DPE ($10\;{\mu}g/ml$), and DNCB ($1\;{\mu}g/ml$), atopic dermatitis induced materials were treated in the culture medium. To investigate cytokine genes expression patterns, with lysis buffer and separation reagent, total RNA was extracted from THP-1, U937, and HMC-1 at intervals of 0, 12, 24, and 48 hours. Both cytokine mRNA expression patterns by atopic dermatitis induced materials and change of cytokine genes expression patterns in relation to atopy by selenium were analyzed with RT-PCR. Also IL-4 and INF-$\gamma$, which were secreted in the HMC-1, were analyzed using ELISA method. Results : 1. After treating THP-1 and U937 with LPS, DPE, and DNCB, there was no significant change in cytokine genes themselves, but various cytokines (IL-4, IL-6, IL-8, IL-13, IFN-$\gamma$, IFN-a, MCP-1, B2-MG) were expressed. 2. In the case of HMC-1, the expressions of IL-6 and IL-8 were significantly increased in the analysis of mRNA expression by dust mite allergens in DPE. 3. As a result of ELISA method, it is certain that IL-4 and IFN-$\gamma$ protein were secreted in the HMC-1 by DPE. 4. Selenium, an essential trace element, decreased the IL-10 and IL-13 expression in the HMC-1 by DPE. Conclusion : The results suggest that it is necessary to choose proper atopic dermatitis induced materials and suitable cultured cells in establishment of in vitro model of atopic dermatitis.

The Relationship of a Child's Need for Approval, Anxiety and Anger-in on a Child's Relational Aggression According to Gender (아동의 성별에 따른 인정욕구, 불안 및 분노억제와 관계적 공격성 간의 관련성)

  • Lee, Young Hwa;Kim, Kyong Yeon
    • Journal of the Korean Home Economics Association
    • /
    • v.51 no.2
    • /
    • pp.219-228
    • /
    • 2013
  • The major purpose of this study was to explore the relation of a child's need for approval, anxiety and anger-in on a child's relational aggression according to gender. The study's participants included 464 boys and girls selected from fifth-and sixth-graders at an elementary school in Busan. A child's need for approval, anxiety, anger-in and relational aggression were assessed with their own self-reports. For data analysis, Cronbach ${\alpha}$, T-test, Pearson correlation coefficients, and Multiple Regression were used. The collected data was analyzed by the SPSSWIN 18.0 program. The major findings were as follows: First, child's anger-in demonstrated a significant difference among sexes. Girls indicated higher points than boys. Second, Boys' need for approval indirectly affected child's relational aggression through anger-in. Boys' anger-in was directly affected by relational aggression. Boys' anxiety was directly affected by anger-in. And boys' anxiety indirectly affected child's relational aggression through anger-in. Third, Girls' anxiety was directly affected by relational aggression. Need for approval and anxiety were directly affected by anger-in. The findings from this study indicates that child's need for approval, anxiety and anger-in are important elements in relational aggression are affected differently depending on the child's gender. Also, this study has meaning in that it can be used as fundamental data to develop a teaching plan and counseling program for children that can decrease relational aggression.

Reconfiguration Problems in VLSI and WSI Cellular Arrays (초대규모 집적 또는 웨이퍼 규모 집적을 이용한 셀룰러 병렬 처리기의 재구현)

  • 한재일
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.18 no.10
    • /
    • pp.1553-1571
    • /
    • 1993
  • A significant amount of research has focused on the development of highly parallel architectures to obtain far more computational power than conventional computer systems. These architectures usually comprise of a large number of processors communicating through an interconnection network. The VLSI (Very Large Scale Integration) and WSI (Wafer Scale Integration) cellular arrays form one important class of those parallel architectures, and consist of a large number of simple processing cells, all on a single chip or wafer, each interconnected only to its neighbors. This paper studies three fundamental issues in these arrays : fault-tolerant reconfiguration. functional reconfiguration, and their integration. The paper examines conventional techniques, and gives an in-depth discussion about fault-tolerant reconfiguration and functional reconfiguration, presenting testing control strategy, configuration control strategy, steps required f4r each reconfiguration, and other relevant topics. The issue of integrating fault tolerant reconfiguration and functional reconfiguration has been addressed only recently. To tackle that problem, the paper identifies the relation between fault tolerant reconfiguration and functional reconfiguration, and discusses appropriate testing and configuration control strategy for integrated reconfiguration on VLSI and WSI cellular arrays.

  • PDF

Characteristics of Plan of Machiya Form of Fishing Village House in the Shikoku District - Focused on Higashimachi Area of Tomoura, Kaifu-cho, Tokushima Prefecture in Japan - (서국(西國) 어촌민가의 마치야 정층(町屋) 형식의 평면특성 - 일본 덕도현(德島縣) 해부정(海部町) 병포 동정(東町)를 중심으로 -)

  • Park, Chan;Kim, Jeong-Gyun
    • Journal of the Korean housing association
    • /
    • v.18 no.1
    • /
    • pp.27-34
    • /
    • 2007
  • The purpose of this study is to examine the characteristics of the plan of fishing village house in the Shikoku district. The research was carried out by field survey and measurement of the traditional house and street system in Higashimachi area of Tomoura. The results of this study are as follows. The traditional house of Higashimachi area is to be taking the plan of Machiya form that is the residence form of a city without being related a fishing village. And the street system is as orderly comparatively as a city. This is not the thing as that is surprised when we think the fact that Higashimachi area has maintained close relation historically with Kyoto, Osaka, etc. However, as for the house of Higashimachi area, the scale is smaller in comparison with Machiya, there is a fundamental difference in terms of the house for the exclusive use of residence. Machiya is the dual constitution of business space and life space. To it the house of Higashimachi area is doing the unitary constitution. Mise is the original opening device (a kind of the front door fitting) of traditional house of Higashimachi area and has the functions that complement narrow space and of offer community space. Finally, the traditional house in this area is equipped with all the residence functions of necessary minimums, although the scale residence is small. It is said that this is the case of a 'small residence' in a Japanese residence.

An Investigation on the Spray Characteristics of a Compressed Natural Gas Injector (고압 천연 가스 인젝터의 분무 특성에 관한 연구)

  • THONGCHAI, SAKDA;KANG, YUJIN;LIM, OCKTAECK
    • Transactions of the Korean hydrogen and new energy society
    • /
    • v.29 no.2
    • /
    • pp.219-225
    • /
    • 2018
  • This study was carried out to investigate the injection characteristics of 800 kPa compressed natural gas compressed natural gas (CNG) injector developed in Korea. The CNG injector with multi-holes, employed in this experiment, was designed to inject CNG in the manifold at high pressure of 800 kPa. The spray macroscopic visualization test was carried out via Schlieren photography to study fuel-air mixing process. The fundamental spray characteristics, such as spray penetration, spray cone angle and spray velocity, were evaluated in the constant volume combustion chamber (CVCC) with varying the constant back pressure in CVCC from 0 to 1.8 bar. For the safety reason, nitrogen ($N_2$) and an acetone tracer were utilized as a surrogate gas fuel instead of CNG. The surrogate gas fuel pressures were controlled at 3, 5.5, and 8 bar, respectively. Injection durations were set at 5 ms throughout the experiment. The simulating events of the low engine speed were arranged at 1,000 rpm. The spray images were recorded by using a high-speed camera with a frame rate of 10,000 f/s at $512{\times}256pixels$. The spray characteristics were analyzed by using the image processing (Matlab). The results showed the significant difference that higher injection pressure had more effect on the spray shape than the lower injection pressure. When the injection pressure was increased, the longer spray penetration occurred. Moreover, the linear relation between speed and time are dependent on the injection pressure as well.

Optimal Design of a Fine Actuator for Optical Pick-up (광픽업 미세구동부의 최적설계)

  • Lee, Moon-G;Gweon, Dae-Gab
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.21 no.5
    • /
    • pp.819-827
    • /
    • 1997
  • In this paper, a new modeling of a fine actuator for an optical pick-up has been proposed and multiobjective optimization of the actuator has been performed. The fine actuator is constituted of the bobbin which is supported by wire suspension, the coils which wind around the bobbin, and the magnets which cause the magnetic flux. If current flows in the coils, magnetic force is so produced as to be balanced with spring force of wire, so the bobbin is pisitioned. In this model the transfer function from input voltage to output displacementof bobbin has been obtained so that we can describe this integrated system with electromagnetic and mechanical parts. Wire suspension is regarded as a continuous Euler beam, damper as distributed viscous damping, and bobbin as a rigid body which can move up- and down- ward motion only. According to the model, the high frequency dynamic characteristics of the fine actuator can be known and the effect of damping can be investigated while the conventional second order model cannot. In multiobjective optimization, two objective functions have been chosen to maximize the fundamental frequency and the sensitivity with respect to the input voltage of the actuator so that Pareto's optimal solutions have been obtained using .epsilon.-constraint method. These objective functions will satisfy the trends which will enhance the access speed and reduce the tracking error in the optical pick-up technology of next generation. In the result of optimization, we obtain the designs of the optical pick-up fine actuator which has high speed, high sensitivity and low resonant peak. Furthermore, we offer the relation between two object functions so that the designer can make easy choice.

CAE/CFD Analysis and Design of High-Pressure Drop Control Valve for Offshore Project (해양플랜트용 고차압 제어밸브의 해석 및 설계)

  • Jang, Sung Cheol;Park, Tae-Soo;Hur, Nam-Soo;Kim, In-Whan
    • Journal of the Korean Society of Manufacturing Process Engineers
    • /
    • v.14 no.5
    • /
    • pp.42-49
    • /
    • 2015
  • In this study, the multi-disk of a high-pressure drop control valve is designed and manufactured. Then, the flow rate and high-pressure drop of fluids flowing in the high-pressure drop control valve is CAE/CFD. This study involves numerical analysis for the Zambil offshore project of a high-pressure drop control valve. ANSYS used a solver for offshore structures analysis. A high-pressure drop control valve, which transforms the power transfer of a system by reducing the inlet pressure of 345bar to the outlet pressure of 112bar, is a fundamental component in the offshore process. This study not only analyzes the relation between pressure drop and fluid velocity in a trim by using fluid analysis, but also examines the possibility of cavitation in a valve in addition to the plot for the extension of lifespan. It is demonstrated that the pressure drop from 345bar to 112bar is more feasible in the presence of the trim, which can induce a continuous and diminutive pressure drop in order to prevent cavitation in a high-pressure drop control valve.

Experimental Study on Peak-Pressure Variation Due to Compression by Using RCM (급속 압축장치(RCM)의 압축 조건에 따른 최대 압력 변화에 관한 실험적 연구)

  • Kim, Hye-Min;Kim, Hak-Young;Baek, Seung-Wook
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.35 no.2
    • /
    • pp.197-204
    • /
    • 2011
  • RCM is used to clarify the complex phenomena of engine combustion. In order to describe engine combustion, several significant experimental studies are considered. Prediction of the peak pressure is very important since it has a significant influence on engine combustion. In addition, peak-temperature variation can be calculated from the measured peak pressure by using the fundamental thermodynamic relation. When the RCM is in operation, heat transfer occurs through the cylinder wall. Because of this phenomenon, it is difficult to determine the peak pressure without employing the case by case experimental method. The goal of this study is to evaluate the peak pressure analytically. We conduct an experiment to confirm the relationship between the peak pressure and some parameters. Using the results of the peak pressure variation experiment, we develop a general equation that be used to calculate the peak pressure as a function of operation time and compression ratio.

울릉분지 돌고래 시추공의 생층서: 고환경 및 이들의 석유탐사에의 응용

  • 이성숙;윤혜수;배부영;박세진;이의형;강소라;김재호;김기현
    • 한국석유지질학회:학술대회논문집
    • /
    • autumn
    • /
    • pp.50-67
    • /
    • 1999
  • Biostratigraphic and paleoenvironmental analyses are carried out on cutting samples from the Dolgorae wells drilled in the Ulleung basin. The clayey, silty, and sandy sediments of the wells yield various microfossil assemblages of relatively good preservation, among which five fossil groups are reported; a total of 97 foraminiferal species of 66 genera, 19 nannofossil species of 12 genera, 86 ostracod species of 41 genera, 107 diatom species of 44 genera, and 124 dinoflagellate cysts species of 45 genera. Based on microfossils the geologic ages of the Dolgorae wells are dated to be from late Early Miocene to Early Pleistocene. Several biohorizons are defined in Neogene successions by the LOD (Last Ocurrence Datum) and FOD (First Ocurrence Datum) of marker species including G. truncatulinoides (LOD: 1.9 Ma) of foraminifera; C. macintyeri (LOD: 1.64-1.60), G. oceanica (FOD: 1.65 Ma), G. caribbeanica (1.72 Ma), D. brouweri (LOD: 2 Ma), R. pseudoumbilica (LOD: 3.66 Ma), P. lacunosa (FOD: 4.2 Ma) of nannofossils; S. ellipsoideus (LOD: 4 Ma), S. palcacantha (LOD: 10.2), C. giusepei (LOD: 14 Ma) of dinocysts; D. seminae v. fossilis (FOD: 3.7 Ma), T. antiqua (LOD: 1.7 Ma), T. convexa (LOD: 2.4 Ma), N. kamtschatica (LOD: 2.58 Ma), T. oestrupii(FOD: 5.1 Ma) of diatoms. Abundance patterns of microfossils throughout the wells reflect changes in paleoenvironmental and sedimentological settings of the basin in relation to sea-level variations. According to these data the large-cycle and small-cycle changes of transgression and regression phases are observed in terrestrial to marine sediments. This high-resolution sequence biostratigraphy established by various fossil groups enabled more reliable correlation between strata and refined interpretation on deposition systems of the basin. It also proved to provide fundamental and precise informations regarding stratigraphic correlation, tectonic events, basin, and depositional history for hydrocarbon explorations, especially in collaboration with seismic-stratigrahic analyses.

  • PDF

The Preference and Purchasing Intention of Traditional Design by Characteristics of Traditional Culture Values and Preferred Style Image of Traditional Design (전통 문화 가치관 특성에 따른 전통 디자인의 선호 및 구매 의도, 전통 디자인의 선호 스타일 이미지)

  • Kim, Seon-Sook;Kim, Angella Ji-Young;Ko, Eun-Ju
    • Journal of the Korean Society of Clothing and Textiles
    • /
    • v.34 no.7
    • /
    • pp.1053-1064
    • /
    • 2010
  • This study investigates the Korean loungewear market and the traditional culture values of consumers related to loungewear to examine the preference of Korean traditional details, sewing techniques in loungewear design, and purchasing intentions. A survey method was used in this study. A total of 230 self-administered questionnaires were obtained from female consumers and 214 data sets were used for analysis. For the analysis, factor analysis, cluster analysis, and ANOVA were executed with PASW Statistics 18.0 and a structural equation model was estimated by Amos 18.0. The results are as follows. Traditional culture values were classified into two dimensions, traditional succession value and traditional design preference value. In the structure equation model, the traditional design preference value had a significant effect on the preference and the traditional culture succession value had significant effect on purchase intention. The results proved that the preference on loungewear with Korean traditional elements is closely related to purchase intention. Consumer groups were divided into three groups by traditional culture values factor; traditional culture succession group, traditional design preference group, and traditional culture indifference group. Style preference images showed significant differences in relation to traditional culture groups. This study is for use as fundamental knowledge on traditional loungewear brand development and strategy planning by offering specific traditional culture aspects associated with preference and purchase intentions.