• The Korean Journal of Malacology
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• v.27 no.3
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• pp.205-211
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• 2011

This study presents physiological rates of oxygen consumption, ammonia excretion, feeding rates, O/N ratio and assimilation efficiency of the blood cockle, Scapharca subcrenata, determined from specimens collected in Yeoja bay on the south coast of Korea. Physiological parameters were measured monthly under static, laboratory controlled conditions with ambient conditions, and measurements were performed seasonally in order to estimate scope for growth and its probable sources of variation. Oxygen consumption and ammonia excretion rates have been increased as temperature increased with the highest value of August, 2008. Feeding rate was the highest during April whereas the lowest was during August which is a period of gametogenesis with minimum biomass of phytoplankton around sampling area. Assimilation efficiency was not significantly different seasonally and O/N ratio decreased during July to August. The scope for growth was negative during high temperature months(July to August), reflecting the high temperature and low feeding rate, and had its highest positive values during spring and autumn. Data on the physiological parameters and scope for growth of Scapharca subcrenata obtained in this study will be used to assess the carrying capacity for blood cockle cultivation.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.13 no.3
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• pp.59-67
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• 1993

The variations of the natural frequencies and the peak response acceleration at the top of prestressed concrete reactor building due to random variability and/or model uncertainty of structural parameters are studied. The results may be used as essential input parameters in seismic probabilistic risk assessment or seismic margin assessment of the reactor building. The sensitivity test of each structural parameter is first performed to determine the most influential parameter upon the natural frequency of structure model. Then Monte Carlo simulation technique is applied to evaluate the effect of parameter variation on the natural frequencies and the peak response acceleration. The acceleration time history is obtained by direct integration scheme. As the study results, it is found that the fundamental natural frequency and the peak response acceleration at the top of the building are most strongly affected by Young's modulus among the structural parameters, in which the value of mean plus one standard deviation obtained by probabilistic approach deviates up to about (+)12% from the result of deterministic method. Considering the uncertainty of flexural rigidity, the structural responses vary in range of (-)4%~(+)14%.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.34 no.2
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• pp.174-184
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• 1998

In order to accumulate fundamental. data for control of fishes’ behavior at the real fishing ground, the fitness of the numerical model for describing the behavior of fishes was examined by the marine fish. Mullet, Mugil cephalus were used as experimental fishes. The numerical model of fishes’ behavior presented in our earlier paper was modified on the vertical movement of fish school. For the comparision of parameters of the modified numerical model between mullet and rainbow trout, the estimated values of parameters were identified with dimension. The fitness of the modified numerical model was examined by the comparision between experiment and simulation on the several indexes represented by fishes’ swimming characteristics. The obtained result are summarized a follows : 1. The non-dimensional parameter a’ of propulsive force and kb’ of interactive force by the experiment without model net showed a similarity, but the non-dimensional parameter k sub(c’) of schooling force for rainbow trout was lager than one for mullet and the non-dimensional parameter k sub(w’) of repulsive force for mullet was lager than one for rainbow trout. 2. The non-dimensional parameter a’ and k sub(b’) for rainbow trout by the experiment with model net were a little lager than ones for mullet, but non-dimensional parameter k sub(c’) and k sub(w’) for mullet were lager than ones for rainbow trout. 3. The non-dimensional parameter k sub(c’) and k sub(b’) showed the largest and the smallest value among the non-dimensional parameters for rainbow trout and mullet, respectively. 4. The fitness of the modified numerical model was confirmed by means of the compulsion between experiment and simulation on the swimming trajectory of fishes, the mean distance of individual from wall, the mean swimming speed, the mean swimming depth and the mean distance between the nearest individuals. Especially, the similarity of mean swimming depth was improved by using the modified numerical model.

• Physical Therapy Korea
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• v.16 no.2
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• pp.16-23
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• 2009

The purpose of this study was to investigate the effects postural changes on respiratory muscles and acoustic parameters of the children with spastic cerebral palsy. Nine children with spastic cerebral palsy who required assistance when walking were selected. The ages of the children ranged from 6 to 9 years old. The phonation of the sustained vowel /a/ and the voice qualities of each child such as fundamental frequency($F_0$; Hz), pitch variation (Jitter; %), amplitude variation (Shimmer; %) and noise to harmonic ratio (NHR) were analyzed by Multi-Dimensional Voice Program (MDVP). The muscle activity of three major respiratory muscles: pectoralis major muscle, upper trapezius muscle and rectus abdorminalis muscle, were measured by examining the root mean square (RMS) of the surface EMG to investigate the impact of changes in the adjusted sitting posture of each subject. However, the RMS of pectoralis major muscle showed a significant differences (p<.05). Secondly, there were no significant differences in $F_0$, Jitter and Shimmer between pre and post posture change, but there was a significant difference in NHR (p<.05). The data were collected in each individual; once prior and once after the sitting posture change. The data were analyzed by Wilcoxon signed ranks-test using SPSS version 14.0 for Windows. The findings of this study were as follows; Firstly, the RMS of upper trapezius and rectus abdorminalis muscle were not significant different between pre and post sitting posture changes. From the result, it is concluded that changes in the adjusted sitting posture decreases the abnormal respiratory patterns in the children with spastic cerebral palsy which is characterized by the hyperactivity of the respiratory muscles in breathing. Also, there is increased on the voice qualities in children with spastic cerebral palsy.

• Journal of the Korean housing association
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• v.21 no.4
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• pp.23-31
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• 2010

This study aims to examine the educational function space of university dormitories at local universities with corridor centered structure in Honam area regions based on direct and indirect parameters on the whole satisfaction of users in residential environment factors and personal characteristics. First, according to relations among parameters, educational and cultural activities of four major activities within the dormitory had indirect influences on social activities, eating and sleeping activities had no direct influence on other activities. And social activity had direct influence on the general satisfaction as an important parameter and educational and cultural activities had indirect influence on the whole satisfaction through social activities. Detailed results show that, in the first educational activities directly affecting the lighting and air conditioning facilities (0.22), safety (0.326), Territoriality (0.327), the space density (-0.167), directions (-0.166) and yeohyang having personal characteristics and the safety of the second cultural activities (0.183), Territoriality (0.361), Aesthetics (-0.13) and the personal characteristics Sex (-0.179), the direct effect, third, and erosion has a direct impact on activity The flexibility of the space factor (-0.128) and Territoriality (0.38) and the personal characteristics grade (0.172), respectively. Fourth in social activities directly affecting the pathfinding (-0.104), and parameter, education (0.388) and cultural activities (0.445), and some of the factors affecting the indirect lighting and air conditioning facilities, safety, and Territoriality, the space density, directions, grade, they could influence through educational activities to be analyzed. That is, territoriality in educational function space is the important factor that users react very sensitively in educational, eating and sleeping activities and educational function space must secure area and division considering personal and public use as the space accommodating activity which is lacking in unit residential space. Accordingly, the safety of educational function space in university dormitory is considered as the fundamental safety matter on the fire prevention, hygiene and cleanness for users in the satisfaction of educational and cultural activities.

• International Journal of Fluid Machinery and Systems
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• v.9 no.4
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• pp.338-353
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• 2016

Information on the surge behaviors and stall stagnation boundaries for a nine-stage axial flow compressor are summarized on the basis of analytical data in comparison with those for a single-stage one, with attention to the pressure ratio effect. The general trends of the surge loop behaviors of the pressure-mass flow are similar for both compressors including the fact that the subharmonic surges tend to appear very near the stall stagnation boundaries. With respect to the nine-stage compressor, however, the mild loops in the subharmonic surges tend to be very small in size relative to the deep loops, and at the same time, insufficient surge recovery phenomenon, which is a kind of subharmonic surge, appears also far from the stagnation boundary for relatively short delivery flow-paths. The latter is found to be a rear-stage surge caused by unstalling and re-stalling of the rear stages with the front-stages kept in stall in the stalled condition of the whole compressor, which situation is caused by stage-wise mismatching in the bottom pressure levels of the in-stall multi-stage compressor. The fundamental information on the stall stagnation boundaries is given by a group of normalized geometrical parameters including relative delivery flow-path length, relative suction flow-path length, and sectional area-pressure ratio, and by another group of normalized frequency parameters including relative surge frequencies, modified reduced resonance frequencies, and modified reduced surge frequencies. Respective groups of the normalized parameters show very similar tendency of behaviors for the nine-stage compressor and the single-stage compressor. The modified reduced resonance frequency could be the more reasonable parameter suggesting the flow-induced oscillation nature of the surge phenomena. It could give the stall stagnation boundary in a more unified manner than the Greitzer's B parameter.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.5
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• pp.333-339
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• 2016

In this paper, a fundamental experiment regarding the formation of porous 3D structures for personal safety products using 3D PPP (Porous Polymer Printing) was introduced for the first time. The filament was manufactured by mixing PP (Polypropylene) and CBA (Chemical Blowing Agent) with polymer extruder, and the diameter of the filament was approximately 1.75mm. The proposed 3D PPP method, combined with the conventional FDM (Fused Deposition Modeling) procedure, was influenced by process parameters, such as the nozzle temperature, printing speed and CBA density. In order to verify the best processing conditions, the depositing parameters were experimentally investigated for the porous polymer structure. These results provide parameters under which to form a multiple of 3D porous polymer structures, as well as various other 3D structures, and help to improve the mechanical shock absorption for personal safety products.

• The Korean Journal of Physiology and Pharmacology
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• v.23 no.4
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• pp.231-236
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• 2019

In drug discovery or preclinical stages of development, potency parameters such as $IC_{50}$, $K_i$, or $K_d$ in vitro have been routinely used to predict the parameters of efficacious exposure (AUC, $C_{min}$, etc.) in humans. However, to our knowledge, the fundamental assumption that the potency in vitro is correlated with the efficacious concentration in vivo in humans has not been investigated extensively. Thus, the present review examined this assumption by comparing a wide range of published pharmacokinetic (PK) and potency data. If the drug potency in vitro and its in vivo effectiveness in humans are well correlated, the steady-state average unbound concentrations in humans [$C_{u_-ss.avg}=f_u{\cdot}F{\cdot}Dose/(CL{\cdot}{\tau})=f_u{\cdot}AUCss/{\tau}$] after treatment with approved dosage regimens should be higher than, or at least comparable to, the potency parameters assessed in vitro. We reviewed the ratios of $C_{u_-ss.avg}$/potency in vitro for a total of 54 drug entities (13 major therapeutic classes) using the dosage, PK, and in vitro potency reported in the published literature. For 54 drugs, the $C_{u_-ss.avg}$/in vitro potency ratios were < 1 for 38 (69%) and < 0.1 for 22 (34%) drugs. When the ratios were plotted against $f_u$ (unbound fraction), "ratio < 1" was predominant for drugs with high protein binding (90% of drugs with $f_u{\leq}5%$; i.e., 28 of 31 drugs). Thus, predicting the in vivo efficacious unbound concentrations in humans using only in vitro potency data and $f_u$ should be avoided, especially for molecules with high protein binding.

• Geomechanics and Engineering
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• v.33 no.1
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• pp.77-89
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• 2023

This study aims to establish the correlations between variables related to a slope during rainfall and factor of safety (FOS) and displacement using a coupling analysis method that is designed to consider both in rainfall conditions. With the recent development of measurement technologies, the approach of using the measurement data in the field has become easier. Particularly, they have been obtained in tests to determine the real-time safety and movement of a slope; however, a specific method has not been finalized. In addition, collected measurement data for recognizing the FOS and displacement in real-time with a specific relevance is difficult, and risks of uncertainty, such as in soil parameters and time, exist. In this study, the correlations between various slope-related variables (i.e., rainfall intensity, rainfall duration, angle of the slope, and mechanical properties including strength parameters of selected three types of soil; loamy sand, silt loam, sand) and the FOS and displacement are analyzed in order of seepage analysis, slope stability analysis and slope displacement analysis. Moreover, the methodology of coupling analysis is verified and a fundamental understanding of the factors that need to be considered in real-time observations is gained. The results show that the contributions of the abovementioned variables vary according to the soil type. Thus, the tendency of the displacement also differs by the soil type and variables but not same tendency with FOS. The friction angle and cohesion are negative while the rainfall duration and rainfall intensity are positive with the displacement. This suggests that understanding their correlations is necessary to determine the safety of a slope in real-time using displacement data. Additionally, databases considering rainfall conditions and a wide range of soil characteristics, including hydraulic and mechanical parameters, should be accumulated.

• Journal of applied mathematics & informatics
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• v.41 no.1
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• pp.51-70
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• 2023

The flow of an incompressible Ellis fluid in an inclined asymmetric channel, driven by peristaltic waves was studied under low Reynolds number and long wavelength assumptions. The wave on each side of the channel are assumed to be an infinite train of sinusoidal waves, both having the same constant wave speed and wavelength however, they vary in wave amplitude, channel half width and phase angle. We derived expressions for the axial and transverse velocities, volume flow rate, pressure rise per unit wavelength and streamlines. The effects of varying the wave amplitudes, the phase angle, the channel width, the angle of inclination of the channel as well as the fluid parameters on the flow were analyzed. Trapping conditions were determined and the presence of reflux highlighted using the streamlines for the necessary channel and fluid conditions. By varying the fluid parameters, changes in the fluid that deviated from the Newtonian case resulted in a reduction in the axial velocity in the neighborhood of the center of the channel and a simultaneous increase in the velocity at the periphery of the channel. A nonlinear relation was observed with the pressure rise and the volume flow rate. This nonlinear relation is more pronounced with an increase in the absolute value of the volume flow rate. For Newtonian fluids a linear relation exists between these two variables. The fluid parameters had little effects on the streamlines. However, variations of the wave amplitudes, volume flow, channel width and phase angle had greater effects on the streamlines and hence the trapped region.