• Title/Summary/Keyword: functional images

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Discrimination of Irradiated Beef Using Comet Assay (Comet assay를 이용한 방사선 조사육의 판별)

  • Jeong, Seok-Kyu;Park, Jong-Heum;Ji, Seung-Taek;Park, Kum-Ju;Kim, Hai-Hong;Hyun, Chang-Kee;Shin, Heuyn-Kil
    • Korean Journal of Food Science and Technology
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    • v.32 no.4
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    • pp.747-754
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    • 2000
  • DNA damages in post-mortem bovine muscle samples caused by gamma irradiation at doses of 1 to 10 kGy were determined by Comet assay. When the cell extract was prepared in a physical method and followed by neutral lysis and neutral electrophoresis, the optimal comet images could be obtained. DNA damages were evaluated from the mean tail length, the distributions of comet images in 4 groups divided by tail length and the relative damage index (RDI) values calculated from the distribution pattern. The mean tail length and RDI value were increased by increasing the irradiation dose, and the RDI value was found to be useful as an index for discriminating of irradiation and measuring the irradiated dose. Blind tests using Korean domestic (Hanwoo) and imported beef samples showed a higher RDI value for the latter. However, the value was lower than those of irradiated samples indicating that the cause of DNA damages in the imported beef samples might be not irradiation but low-temperature treatments. It was concluded from the results of this study that the irradiated beef and its irradiated dose could be detected and predicted by Comet assay.

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Developing a Korean Standard Brain Atlas on the basis of Statistical and Probabilistic Approach and Visualization tool for Functional image analysis (확률 및 통계적 개념에 근거한 한국인 표준 뇌 지도 작성 및 기능 영상 분석을 위한 가시화 방법에 관한 연구)

  • Koo, B.B.;Lee, J.M.;Kim, J.S.;Lee, J.S.;Kim, I.Y.;Kim, J.J.;Lee, D.S.;Kwon, J.S.;Kim, S.I.
    • The Korean Journal of Nuclear Medicine
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    • v.37 no.3
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    • pp.162-170
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    • 2003
  • The probabilistic anatomical maps are used to localize the functional neuro-images and morphological variability. The quantitative indicator is very important to inquire the anatomical position of an activated legion because functional image data has the low-resolution nature and no inherent anatomical information. Although previously developed MNI probabilistic anatomical map was enough to localize the data, it was not suitable for the Korean brains because of the morphological difference between Occidental and Oriental. In this study, we develop a probabilistic anatomical map for Korean normal brain. Normal 75 blains of T1-weighted spoiled gradient echo magnetic resonance images were acquired on a 1.5-T GESIGNA scanner. Then, a standard brain is selected in the group through a clinician searches a brain of the average property in the Talairach coordinate system. With the standard brain, an anatomist delineates 89 regions of interest (ROI) parcellating cortical and subcortical areas. The parcellated ROIs of the standard are warped and overlapped into each brain by maximizing intensity similarity. And every brain is automatically labeledwith the registered ROIs. Each of the same-labeled region is linearly normalize to the standard brain, and the occurrence of each legion is counted. Finally, 89 probabilistic ROI volumes are generated. This paper presents a probabilistic anatomical map for localizing the functional and structural analysis of Korean normal brain. In the future, we'll develop the group specific probabilistic anatomical maps of OCD and schizophrenia disease.

Visualization and Localization of Fusion Image Using VRML for Three-dimensional Modeling of Epileptic Seizure Focus (VRML을 이용한 융합 영상에서 간질환자 발작 진원지의 3차원적 가시화와 위치 측정 구현)

  • 이상호;김동현;유선국;정해조;윤미진;손혜경;강원석;이종두;김희중
    • Progress in Medical Physics
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    • v.14 no.1
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    • pp.34-42
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    • 2003
  • In medical imaging, three-dimensional (3D) display using Virtual Reality Modeling Language (VRML) as a portable file format can give intuitive information more efficiently on the World Wide Web (WWW). The web-based 3D visualization of functional images combined with anatomical images has not studied much in systematic ways. The goal of this study was to achieve a simultaneous observation of 3D anatomic and functional models with planar images on the WWW, providing their locational information in 3D space with a measuring implement using VRML. MRI and ictal-interictal SPECT images were obtained from one epileptic patient. Subtraction ictal SPECT co-registered to MRI (SISCOM) was performed to improve identification of a seizure focus. SISCOM image volumes were held by thresholds above one standard deviation (1-SD) and two standard deviations (2-SD). SISCOM foci and boundaries of gray matter, white matter, and cerebrospinal fluid (CSF) in the MRI volume were segmented and rendered to VRML polygonal surfaces by marching cube algorithm. Line profiles of x and y-axis that represent real lengths on an image were acquired and their maximum lengths were the same as 211.67 mm. The real size vs. the rendered VRML surface size was approximately the ratio of 1 to 605.9. A VRML measuring tool was made and merged with previous VRML surfaces. User interface tools were embedded with Java Script routines to display MRI planar images as cross sections of 3D surface models and to set transparencies of 3D surface models. When transparencies of 3D surface models were properly controlled, a fused display of the brain geometry with 3D distributions of focal activated regions provided intuitively spatial correlations among three 3D surface models. The epileptic seizure focus was in the right temporal lobe of the brain. The real position of the seizure focus could be verified by the VRML measuring tool and the anatomy corresponding to the seizure focus could be confirmed by MRI planar images crossing 3D surface models. The VRML application developed in this study may have several advantages. Firstly, 3D fused display and control of anatomic and functional image were achieved on the m. Secondly, the vector analysis of a 3D surface model was defined by the VRML measuring tool based on the real size. Finally, the anatomy corresponding to the seizure focus was intuitively detected by correlations with MRI images. Our web based visualization of 3-D fusion image and its localization will be a help to online research and education in diagnostic radiology, therapeutic radiology, and surgery applications.

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Dependency of Generator Performance on T1 and T2 weights of the Input MR Images in developing a CycleGan based CT image generator from MR images (CycleGan 딥러닝기반 인공CT영상 생성성능에 대한 입력 MR영상의 T1 및 T2 가중방식의 영향)

  • Samuel Lee;Jonghun Jeong;Jinyoung Kim;Yeon Soo Lee
    • Journal of the Korean Society of Radiology
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    • v.18 no.1
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    • pp.37-44
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    • 2024
  • Even though MR can reveal excellent soft-tissue contrast and functional information, CT is also required for electron density information for accurate dose calculation in Radiotherapy. For the fusion of MRI and CT images in RT treatment planning workflow, patients are normally scanned on both MRI and CT imaging modalities. Recently deep-learning-based generations of CT images from MR images became possible owing to machine learning technology. This eliminated CT scanning work. This study implemented a CycleGan deep-learning-based CT image generation from MR images. Three CT generators whose learning is based on T1- , T2- , or T1-&T2-weighted MR images were created, respectively. We found that the T1-weighted MR image-based generator can generate better than other CT generators when T1-weighted MR images are input. In contrast, a T2-weighted MR image-based generator can generate better than other CT generators do when T2-weighted MR images are input. The results say that the CT generator from MR images is just outside the practical clinics and the specific weight MR image-based machine-learning generator can generate better CT images than other sequence MR image-based generators do.

Future Image Expressed in Contemporary Fashion Design (현대 의상 디자인에 나타난 미래 이미지)

  • 이유경
    • The Research Journal of the Costume Culture
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    • v.6 no.4
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    • pp.188-202
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    • 1998
  • The purpose of this study is to analyze how future images are embodied in contemporary fashion design. To find out future images expressed in contemporary fashion design, this paper characterized the future society as information society, network society, pluralistic society, and global village. Cyber design and techno-style expressed through metal or lustrous material which is influenced by information symbolize future image. Also, minimalism which is characterized as simplicity and purity affects the contemporary fashion design. The network society which affets t the horizontal and functional social system diminishes the meaning of socio-economic status. Therefore, street fashion has diffused to high fashion, and the formal wear has tendency to be changed into casual wear. In addition, the meaning of status symbol in contemporary fashion design become decreased. The pluralistic society affects to search for one's own personality and identity. Also, contemporary fashion design is influenced by post-modernism and deconstructionism. In order words, genderless, ageles, seasonless, and infra fashion appeared. The global village emphasizes extension of universality in life style and search for world quality. so, ethnic fashions appear frequently in contemporary fashion design. Also, the effects of Korean traditional costume to contemporary fashion design has increased.

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Quality Assurance and Performance Evaluation of PET/CT (핵의학 영상장비 PET/CT의 정도관리와 성능평가)

  • Lee, Byeong-Il
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.2
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    • pp.137-144
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    • 2008
  • Positron emission tomography-computed tomography (PET/CT) provides both functional and anatomical images of high quality non-invasively with better precision in localization than PET alone. Increase in the use of PET/CT, coupled with increasing concerns about the quality of medical services accrued the demands for accurate evaluation of system performance and quality assurance. Thus, well designed programs for performance evaluation and quality assurance are needed. Widely used protocols for performance evaluation of PET are the methods proposed by National Electrical Manufacturers Association (NEMA) in 1994 and 2001. In addition, in order to maintain high quality of PET/CT images, quality assurance programs including periodic (daily, monthly, and yearly). Therefore, in this article, the methods and present state of performance evaluation and quality assurance of PET/CT are reviewed.

Cerebellar Schistosomiasis: A Case Report with Clinical Analysis

  • Wan, Heng;Lei, Ding;Mao, Qing
    • Parasites, Hosts and Diseases
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    • v.47 no.1
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    • pp.53-56
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    • 2009
  • The authors report here a rare case of cerebellar schistosomiasis identified by pathological diagnosis, lacking extracranial involvement. The clinical symptoms included headache, dizziness, and nausea. Studies in blood were normal and no parasite eggs were detected in stool. Computed tomography of brains showed hypodense signal, and magnetic resonance imaging showed isointense signal on T1-weighted images, hyperintense signal on T2-weighted images, and intensely enhancing nodules in the right cerebellum after intravenous administration of gadolinium. A high-grade glioma was suspected, and an operation was performed. The pathologic examination of the biopsy specimen revealed schistosomal granulomas scattered within the parenchyma of the cerebellum. The definitive diagnosis was cerebellar schistosomiasis japonica. A standard use of praziquantel and corticosteroid drugs was applied, and the prognosis was good. When the pattern of imaging examinations is present as mentioned above, a diagnosis of brain schistosomiasis should be considered.

Functional Exploration of Optokinetic System by a Full Visual Field Stimulation

  • Kim Nam Gyun;KOPP C.
    • Journal of Biomedical Engineering Research
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    • v.10 no.2
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    • pp.125-130
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    • 1989
  • In the present study, we described a test to explore the function of optokinetic system which subjected to a full visual field stimulation using two different stimulus images patterns. Our results were interesting in a point of view that the stimulation image pattern had non- neglisible influence on the optokinetic response and that in a bidimensionnel image such as the randomly distributed spots images pattern the linearity of system was assured upto the stimulus velocity of about 50 deg/sec for normal subject. As for measuring human optokinetic after nystagmus, the regular stripes pattern was rather desirable than the randomly distributed spots pattern in this study.

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Functional Analysis of Music Used in Film

A Variational Model For Longitudinal Brain Tissue Segmentation

  • Tang, Mingjun;Chen, Renwen;You, Zijuan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.16 no.11
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    • pp.3479-3492
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    • 2022
  • Longitudinal quantification of brain changes due to development, aging or disease plays an important role in the filed of personalized-medicine applications. However, due to the temporal variability in shape and different imaging equipment and parameters, estimating anatomical changes in longitudinal studies is significantly challenging. In this paper, a longitudinal Magnetic Resonance(MR) brain image segmentation algorithm proposed by combining intensity information and anisotropic smoothness term which contain a spatial smoothness constraint and longitudinal consistent constraint into a variational framework. The minimization of the proposed energy functional is strictly and effectively derived from a fast optimization algorithm. A large number of experimental results show that the proposed method can guarantee segmentation accuracy and longitudinal consistency in both simulated and real longitudinal MR brain images for analysis of anatomical changes over time.