• Journal of Microbiology and Biotechnology
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• 제16권5호
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• pp.748-756
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• 2006

We propose a genome-scale clustering approach to identify whole genome relationships using the functional groups given by the Kyoto Encyclopedia of Genes and Genomes Orthology (KO) database. The metabolic capabilities of each organism were defined by the number of genes in each functional category. The archaeal, bacterial, and eukaryotic genomes were compared by simultaneously applying a two-step clustering method, comprised of a self-organizing tree algorithm followed by unsupervised hierarchical clustering. The clustering results were consistent with various phenotypic characteristics of the organisms analyzed and, additionally, showed a different aspect of the relationship between genomes that have previously been established through rRNA-based comparisons. The proposed approach to collect and cluster the metabolic functional capabilities of organisms should make it a useful tool in predicting relationships among organisms.

• 대한한방내과학회지
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• 제35권2호
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• pp.157-174
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• 2014

Objectives : The aims of this study were to evaluate the diagnostic values of tongue coating thickness and sterno-costal angle as the quantitative diagnostic indicators in functional dyspepsia. Methods : We surveyed 60 functional dyspepsia patients recruited by the clinical trial, 'Clinical Trial for Evaluation on Availability of tongue diagnosis system (CTS-1000) : a Pilot study'. The patients were classified into three groups according to Rome III criteria for functional dyspepsia, and categorized into five groups according to Instrument of pattern identification for functional dyspepsia. Nepean dyspepsia index-Korean version (NDI-K) score, tongue coating thickness (percentage of tongue coating by tongue diagnosis system (CTS-1000), and weight of tongue coating by microbalance), sterno-costal angle, duration of illness and body mass index (BMI) were investigated. Results : Among the 5 types by instrument of pattern identification for functional dyspepsia, a significant difference of percentage of tongue coating was found. Percentage of tongue coating and weight of tongue coating showed significant correlation with total NDI-K score. Sterno-costal angle showed strong positive correlation with BMI and also showed significant difference between the non-overweight (BMI<23, n=32) and overweight ($BMI{\geq}23$, n=28) groups. Conclusions : Tongue coating thickness showed its potential as a new quantitative diagnostic indicator of functional dyspepsia. Further studies on the sterno-costal angle are anticipated to evaluate its potential as a new quantitative diagnostic indicator.

• 동의신경정신과학회지
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• 제21권2호
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• pp.75-85
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• 2010

Objectives : This study was designed to evaluate the correlation between patterns of dyspepsia(acute dyspepsia, functional dyspepsia, dyspepsia with the organic disease) and autonomic nerve system dysfunction using HRV analysis. Methods : The patient group consisted of 88 patients diagnosed as a dyspepsia (Acute dyspepsia group-35 patients, Functional dyspepsia group-28 patients, Dyspepsia with the organic disease group-28 patients) who visited in the Oriental Medical Hospital of Dong-eui University from 2005.3.OO to 2008.8.OO. And the control group consisted of 33 patients diagnosed as a normal state of stomach during the same period. We checked HRV of the 4 groups over 5 minutes and compared the HRV index between groups. Results : 1. HF, LF, VLF and TP were significantly lower in the acute dyspepsia, functional dyspepsia and organic dyspepsia patient group than in the control group. 2. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. 3. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the functional dyspepsia patient group, but the differences were not statistically significant. 4. HF, LF, VLF and TP were lower in the functional dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. Conclusions : Compared to the control group, all of the dyspepsia patient groups showed the tendency that the overall activity of the autonomic nervous system and the activity of sympathetic nerves decreased. Although there was no significant difference in the suppression of the autonomic nervous system, chronic dyspepsia patient group was lower than acute dyspepsia patient group, functional dyspepsia patient group was lower than the organic dyspepsia patient group in HRV.

• 접착 및 계면
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• 제1권1호
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• pp.23-29
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• 2000

소수성 고분자 재료 표면의 친수화 처리 및 기능성 작용기 도입은 재료의 응용성을 상당히 확장할 수가 있기 때문에 중요성이 인지되고 있다. 본 연구에서는 기상 UV 그라프트 반응(vapor phase photografting)에 의해 서로 다른 이온성을 가지는 비닐계 단량체들을 PE 표면에 도입하여 표면 친수성을 향상시켰다. 이를 위해 acrylic acid(음이온성), acrylamide(중성), allylalcohol(중성), allylamine(양이온성) N,N-dimethyl aminopropyl acrylamide(양이온성) 등 서로 다른 기능성 작용기를 갖는 친수성 단량체들을 본 실험실에서 고안한 기상 UV 그라프트 반응장치를 이용하여 기체상태에서 PE 표면에 도입하였다. 이들 단량체들이 도입된 PE 표면을 물 접촉각 측정과 ATR-FTIR을 이용하여 분석한 결과, 각 기능성 단량체들이 효과적으로 PE 표면에 그라프트되어 표면의 친수성이 향상되었음을 확인할 수 있었다. 본 연구에 사용한 기상 UV 그라프트 반응은 고분자 표면에 다양한 작용기를 도입하여 표면을 개질할 수 있는 효과적인 방법으로 생각되어진다.

• 감성과학
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• 제18권4호
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• pp.75-86
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• 2015

본 연구는 기업과 소비자 간의 기능성 의류제품의 효과적인 정보소통을 목적으로 하는 일련의 연구 중 일부로 기능성 아웃도어 재킷에 대한 인식과 행동양식에 따라 응답자를 유형화하고 각 유형별 기능성 아웃도어 재킷 구매시 활용하는 정보원과 행택에 대한 행동의 차이를 고찰하였다. 설문조사는 기능성 아웃도어 재킷 구매 경험이 있는 20~60대 남, 녀 472명을 대상으로 실시하였다. 기능성 아웃도어 재킷에 대한 인식은 '기능성', '가격', '경험/지식', '브랜드/디자인' 요인으로 분류되었으며 요인에 따라 응답자들은 '비전문적/브랜드 및 디자인 추구집단', '전문적/기능성 중시집단', '고가제품 선호집단'으로 분류되었다. '비전문적/브랜드 및 디자인 추구집단'은 인터넷을 정보를 가장 많이 활용하는 20대, 30대의 회사원과 학생으로 구성되었으며 '전문적/기능성 중시집단'의 경우에는 행택(Hang-Tag)을 정보원으로 주로 사용하는 전문직의 40대, 50대가 주를 이루었다. '고가제품 선호집단'은 60대 이상, 주부의 비율이 가장 높은 집단으로 판매원을 정보원으로 주로 이용하는 것으로 나타났다. 기능성 정보제공에 사용된 용어에 대해 설명의 필요성을 가장 높게 인식하고 있는 집단은 '전문적/기능성 중시집단'이었으며 성능정보 관심도가 떨어지는 '비전문적/브랜드 및 디자인 추구집단'은 오히려 상대적 만족도가 높은 것으로 나타났다. 본 연구를 통해 기능성 재킷 소비자 유형의 특징과 성능 정보에 대한 반응의 차이를 고찰함으로써 기능성 의류제품의 성능 정보 제공을 위한 효과적인 방법과 내용에 대한 실질적이고 유용한 정보를 제공할 수 있을 것으로 기대한다.

• 한국융합학회논문지
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• 제11권3호
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• pp.245-252
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• 2020

본 연구는 요가, 필라테스, 코어운동 등 체간 안정성 운동프로그램 적용 전후의 만성 요통 환자의 기능적 움직임, 동적 균형능력 및 체간 안정성의 변화를 확인하고, 3가지 체간 안정성 운동의 효과를 비교하고자 하였다. 만성 요통을 가진 성인 43명을 요가 집단 (n=15)과 필라테스 집단 (n=15) 및 코어 운동 집단 (n=13)으로 분류하였고, Functional Movement Screen (FMS)와 Lower Quater Y-Balance Test (YBT-LQ) 및 Trunk Stability Test (TST)를 통해 기능적 움직임, 동적 균형능력 및 체간 안정성을 각각 측정하였다. 이후 8주간 운동을 적용한 후 모든 변인을 재측정하였으며, 운동 적용 전후 차이를 비교 분석하였다. 그 결과, 세 집단 모두 운동 적용 후 FMS, YBT-LQ 및 TST의 측정값이 적용 전보다 유의하게 증가하였으나, 각 운동 적용에 따른 집단 간의 차이는 나타나지 않았다. 이런 결과는 요가, 필라테스 및 코어 운동이 만성 요통 환자의 기능적 움직임, 동적 균형능력 및 체간 안정성을 개선하는 데 도움이 된다는 것을 보여주었다.

• The Journal of Korean Physical Therapy
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• 제29권4호
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• pp.207-210
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• 2017

Purpose: This study was to identify the effectiveness of high-intensity laser therapy on pain and function of a frozen shoulder. Methods: Thirty patients were assigned to two groups: the experimental group (n=15) and the control group (n=15). Both groups received traditional therapy for 4 weeks, 3 days a week. The experimental group, however, received an additional high intensity laser therapy. Pain was measured using the visual analogue scale (VAS). The functional ability was measured using the patient specific functional scale (PSFS). A paired t-test was used to determine any differences before and after the treatment, and an independent t-test was used to determine any differences between treatment groups. Results: Both groups showed a statistically significant difference for VAS and PSFS score (p<0.05). In comparison between two groups, more experimental group than control group statistically significant difference (p<0.05). Conclusion: There seems to be a positive effect on pain and function of frozen shoulder from using high intensity laser therapy.

• 공업화학
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• 제21권4호
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• pp.396-400
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• 2010

본 연구에서는 킬레이트 관능기가 도입된 활성탄소의 이산화탄소 흡착거동에 관하여 고찰하였다. 활성탄소에 peroxide의 열분해를 통해 glycidyl methacrylate를 그래프트 중합한 후 에폭사이드기에 킬레이트 관능기로서 diethylene triamine을 도입하였다. 킬레이트 관능기가 처리된 활성탄소의 표면특성은 scanning electron microscope와 X-ray photoelectron spectroscopy를 사용하여 측정하였으며, 흡착표면적과 기공도는 BET법을 이용한 $N_2$ 기체 흡착을 통해 알아보았다. 또한 킬레이트 관능기 처리된 활성탄소의 흡착특성을 비교하기 위해 이산화탄소의 흡착실험을 수행하였다. 실험 결과, 활성탄소 표면에 도입된 킬레이트 관능기는 비표면적 감소에 따른 물리적 흡착량이 감소하더라도 이산화탄소에 대한 선택적, 화학적 흡착량을 향상시킴을 알 수 있었다.

• 한국전문물리치료학회지
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• 제26권4호
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• pp.10-19
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• 2019

Background: In patients with lumbar spinal stenosis (LSS), lumbar flexion exercise (LFE) is considered a standard therapeutic exercise that widens the space between the spinal canal and intervertebral foramen. However, some researchers have reported that lumbar extension exercise (LEE) may improve lumbar pain and functional ability in patients with LSS. Although exercise intervention methods for patients with LSS have been widely applied in clinical settings, few studies have conducted comparative analysis of these exercise methods. Objects: This study aimed to compare the effects of LFE, LEE, and lumbar flexion combined with lumbar flexion-extension exercise (LFEE) on pain, range of motion (ROM), pelvic tilt angle, and functional gait ability in patients with LSS. Methods: A total of 30 patients with LSS, LFE (n1=10), LEE (n2=10), and LFEE (n3=10) were assigned to each of the three exercise groups. The numerical pain rating scale (NPRS), modified-modified schober test (MMST)-flexion, MMST-extension, pelvic tilt inclinometer, and 6-minute walking test (6MWT) were measured. Results: After the intervention, statistically significant differences were observed in the NPRS (p=.043), MMST-flexion (p<.001), MMST-extension (p<.001), and 6MWT (p=.005) between groups. According to the post hoc test, the NPRS was statistically significant difference between the LFEE and LEE groups (p=.034). The MMST-flexion was statistically significantly different between the LFE and LEE (p=.000), LFE and LFEE (p=.001), and LEE and LFEE (p=.001) groups. The MMST-extension was statistically significantly different between the LFE and LEE (p<.001), LFE and LFEE (p=.002), and LEE and LFEE (p=.008) groups. The 6MWT was statistically significantly different between the LFE and LFEE (p=.042) and the LEE and LFEE (p=.004) groups. Conclusion: This study suggested that LFEE was the most effective exercise for pain and functional gait ability in patients with LSS, LFE was the most effective exercise for lumbar flexion ROM, and LEE was the most effective exercise for lumbar extension ROM.

• PNF and Movement
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• 제12권3호
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• pp.143-150
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• 2014

Purpose: The corticospinal tract (CST) is known to be an important pyramidal tract for walking and motor function. However, very little is known about the functional role of the CST in the recovery of motor function. In the current study, we investigated the relation between the CST and motor function in chronic hemiparetic stroke patients. Methods: Fifty-four patients and 20 normal subjects were recruited. The Functional Ambulation Category (FAC) was used in measurement of the walking ability. We classified patients into three groups according to the ability to walk independently: group A, patients who could not walk independently (FAC: 0-2); group B, patients who could walk independently (FAC: 3); and group C, patd walk functionally (stairs and uneven surfaces, FAC 4-5). The Motricity Index (MI) was used to measure the motor function of the affected upper and lower extremities (maximum score: 100). The fractional anisotropy (FA) value, apparent diffusion coefficient (ADC) value, and fiber volume of the CST were used for the diffusion tensor imaging (DTI) parameters. Results: In terms of the CST of the unaffected hemisphere, the FA value of group A was significantly lower than that of normal controls (p <0.05). The fiber volume of group C was significantly higher than that of normal controls (p <0.05). In contrast, the ADC values of all patient groups and the control group did not show any difference (p >0.05). In terms of lower MI and total MI, significant differences were observed between all patient groups (p <0.05). In addition, significant differences in terms of the upper MI scores were observed between groups A and C and between groups B and C (p <0.05); however, no significant difference was observed between groups A and B (p>0.05). Conclusion: The increased fiber volume of the CST in the unaffected hemisphere appears to be related to functional walking ability in chronic stroke patients. This result would be useful for elucidation of the neural recovery mechanism of walking and the investigation of new modalities for the recovery of walking following a stroke with CST injury.