• 제목/요약/키워드: functional group analysis

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동적 타액선 신티그라피에서 기능적 매개변수 지표를 활용한 정량 분석의 유용성 (Usefulness of the quantitative analysis by using the functional parameter index from dynamic salivary glands scintigraphy)

  • 신채호;김봉수;조용귀;조진우;진성은;표성재
    • 핵의학기술
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    • 제19권2호
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    • pp.81-86
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    • 2015
  • 동적 타액선 신티그라피는 비침습적인 방법으로 타액선의 기능을 평가하는데 널리 사용되어 왔다. 본 연구에서는 타액선 신티그라피의 시간-방사능 곡선에서 다양한 기능적 매개변수지표를 측정하고 구강건조증 환자 그룹과 건강한 Control 그룹과 비교를 통해 유용성을 알아보고자 한다. 2014년 12월부터 2015년 2월까지 구강 건조증으로 내원하여 동적 타액선 신티그라피를 시행한 환자 그룹 30명과 건강한 Control 그룹 10명을 대상으로 하였다. 검사방법은 370 MBq의 $^{99m}Tc$-과산화테크네슘을 정맥으로 순간 주사 후 약 30분간 동적 타액선 신티그라피를 연속 촬영하였으며, 주사 후 20분째에 최타 자극제로 비타민C 파우더를 이용하였다. 정량분석은 이하선과 악하선의 시간-방사능 곡선을 통해 기능적 매개변수 지표를 획득하고, 통계 프로그램을 이용하여 구강 건조증 환자와 건강한 Control 그룹과 비교하였다. 동적 타액선 신티그라피에서 이하선과 악하선의 기능적 매개변수 지표인 섭취율(Uptake Ratio, UR), 최대 방사능 시간(Time at Maximum counts, Tmax), 최소 방사능 시간(Time at Minimum counts, Tmin), 최대 축적율(Maximum Accumulation, MA), 축적속도(Accumulation Velocity), 최대 배출율(Maximum Secretion, MS), 최대 자극 배출율(Maximum Stimulation Secretion, MSS), 배출속도(Secretion Velocity, SV)를 각각 측정하였다. 구강 건조증 환자와 건강한 Control 그룹간의 이하선과 악하선의 기능적 매개변수 지표 비교에서는 최소 방사능 시간을 제외한 모든 지표에서 건강한 Control 그룹이 환자 그룹에 비하여 유의성 있게 높게 측정되었으며, 시간에 따른 변화량도 Control 그룹이 환자 그룹에 비하여 유의성 있게 변화량이 크게 측정 되었다. 동적 타액선 신티그라피에서 다양한 기능적 매개변수 지표를 이용한 정량분석은 구강 건조증 환자의 타액선 기능을 평가하는데 객관적이고 표준화된 정보를 제공해 줄 것으로 사료된다.

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기능성소화불량에서 위기허증(胃氣虛證)과 복부초음파로 측정한 위 배출능과의 상관성 분석 (Correlation Analysis Between Stomach Qi Deficiency Pattern and Gastric Emptying Measured by Abdominal Ultrasonography in Patients with Functional Dyspepsia)

  • 남성욱;박재우;김진성
    • 대한한방내과학회지
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    • 제39권3호
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    • pp.405-425
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    • 2018
  • Objective: The purpose of this study was to analyze the correlation between Stomach Qi Deficiency and gastric emptying as measured by abdominal ultrasonography in postprandial distress syndrome (PDS), a subgroup of functional dyspepsia (FD). Methods: Ten patients who met the Rome III diagnostic criteria for PDS and ten healthy controls participated in this study Gastric emptying shown as the half-life of gastric volume ($T_{1/2}$) was measured by abdominal ultrasonography. The degree of Stomach Qi Deficiency was assessed using the scale for Stomach Qi Deficiency pattern (SSQD). In addition, functional dyspepsia-related quality of life (FD-QoL), Nepean dyspepsia index-Korean version (NDI-K), and visual analogue scale (VAS) of distention and fullness were conducted on all subjects. Results: The scores of SSQD, FD-QoL, NDI-K, and VAS of distention and fullness in the patient group were significantly higher than those in the control group (p<0.05). $T_{1/2}$ was also higher in the patient group than in the control group. The SSQD score significantly correlated positively with $T_{1/2}$ in the patient group (r=0.640, p=0.046). However, there was no significant correlation between $T_{1/2}$ and other questionnaire scores in the patient group. Conclusions: Our results suggest that the gastric emptying measured by abdominal ultrasonography could be a quantitative indicator to diagnose Stomach Qi Deficiency in FD patients, especially the PDS subtype.

기능성 소화불량증 환자의 심리특성에 관한 연구 (An Investigation of Psychological Factors in Patients with Functional Dyspepsia)

  • 김진성;배대석;이광헌;서정일
    • Journal of Yeungnam Medical Science
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    • 제16권2호
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    • pp.244-254
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    • 1999
  • 1998년 1월 1일부터 12월 31일까지 영남대학교와 동국대학교 의과대학 부속병원을 내원한 기능성 소화불량증 환자 90명의 심리적 특성을 알아보기 위하여, 정신과 외래 환자 64명을 대조군으로 하여 다면적 인성검사와 질병행동 설문지 조사를 실시하였으며, 그 결과는 다음과 같다. 다면적 인성검사를 통한 비교에서, 기능성 소화불량증 환자군과 정신과 외래환자군 사이에 유의한 차이가 없이 유사한 성적분포를 보였다. 양군에서 건강염려증, 우울증, 히스테리 척도에서 상대적으로 높은 점수를 보였다. 질병행동 설문지를 통한 비교에서 기능성 소화불량증 환자군이 정신과 외래환자군보다 질병집착심과 정서적 혼란 소척도에서 성적이 낮게 나왔으며, 다른 소척도들은 비슷한 성적분포를 보였다. 다면적 인성검사 성적을 이용하여 기능성 소화불량증 환자를 중다변인 군집분석한 결과, 정신과 외래의 신경증환자와 같은 집단<집단 1>, 정상인과 같은 집단<집단 2>, 신경증적 경향이 심한 집단<집단 3>으로 나눌 수 있었다. 분류된 집단들 간의 다면적 인성검사 성적 비교에서, 신경증적 경향이 심한 집단<집단 3>은, 건강염려증, 우울증, 히스테리, 강박증, 정신분열증 등의 소척도 점수가 높게 나왔다(P<.05). 신경증적인 경향이 심한 집단<집단 3>의 질병행동 설문지 결과를 보면 다른 집단들과 정서적 억압척도를 제외한 모든 척도 즉, 건강염려증, 질병집착심, 심리적 대 신체적 관심, 정서적 혼란, 부정, 자극과민성 등의 척도에서 유의하게 차이가 있는 것으로 나타났다(P<.05). <집단 3>처럼 심한 신경증적인 질병행동을 보이는 군은 정신의학적 접근이 도움을 줄 수 있는 집단이다.

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노년층 소비자의 기능성 소재 추구 혜택, 태도 및 구매 의도에 관한 연구 (A Study of Older Consumers' Seeking Benefits and Purchase Intentions for and Their Attitudes towards Functional Materials)

  • 홍경희;최인려
    • 복식문화연구
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    • 제17권1호
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    • pp.149-161
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    • 2009
  • The purposes of this study are to examine older consumers' seeking benefits and purchase intentions for functional materials and their attitudes towards such materials and investigate the differences between purchasers and non-purchasers of functional materials in their seeking benefits for functional materials and their emphasis on self development and pursuit of fashion. In doing so, this study samples the older adult population living in Seoul, Busan, and Gyeonggi Province and analyzes 267 questionnaire responses obtained from the sampled older consumers. The main findings from the analysis are as follows: First, the older consumers' seeking benefits for functional materials were represented by three different dimensions: reliability, brands/fashion, and others-oriented pursuit. Second, the influence on the dimension of reliability was more significant in the order of knowledge on functional materials, pursuit of fashion, and emphasis on self-development the interest in garments and the pursuit of fashion were found to have significant influence on the dimensions of brands/fashion and others-oriented pursuit. Third, the respondents' attitudes towards functional materials showed significant correlations with the dimensions of reliability and others-oriented pursuit, while their purchase intentions for functional materials were significantly influenced by the dimensions of reliability and brands/fashion. Finally, when the differences in the respondents' seeking benefits for functional materials and their pursuit of fashion and emphasis on self-development were investigated according to whether or not they had ever purchased clothes made from any functional material, the group of purchasers showed a higher mean value than the non-purchaser group.

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만성 요통 환자에게 미세전류의 적용이 통증 및 기능에 미치는 영향 (The Influence of Microcurrent on Pain and Function of Patients with Chronic Back Pain)

  • 박장성;정화수
    • 대한임상전기생리학회지
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    • 제8권1호
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    • pp.1-5
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    • 2010
  • Purpose : This research inquires into the effect of applying microcurrent (MC) according to various frequency levels on the pain and functional recovery of patients with chronic back pain. Methods : Thirty participants with chronic lower back pain disease were divided equally into three experimenta l groups. The MC frequency used in the first experimental group was 0.5Hz, the second experimental group was 50Hz, and the third experimental group was 100Hz for 20 minute sessions. A hot pack and ultrasound were applied to all groups as the general physical therapy. Measurements were taken using the visual analogue scale (VAS), the face pain rating scale (FPRS), and the Oswestry disability index (001). The analysis used the paired t-test in order to compare pretest and posttest results. A one-way ANOVA was performed to make comparisons with regards to frequency levels. Results : VAS, FPRS, and 001 showed significant pain decrease in all groups except for the 001 measurement in the 0.5 Hz group. There were no significant differences according to frequency levels. Conclusion: For chronic pain and functional recovery, a microcurrent produces an effect after treatment. However, results did not show a significant difference in change obtained from differing frequency levels.

Effect of Coagulant Type on the Silica Dispersion and Properties of Functionalized RAFT ESBR Silica Wet Masterbatch

  • Kim, Woong;Ryu, Gyeongchan;Hwang, Kiwon;Song, Sanghoon;Kim, Wonho
    • Elastomers and Composites
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    • 제55권3호
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    • pp.167-175
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    • 2020
  • Various studies have been conducted to improve silica dispersion of silica filled tire tread compounds; among them, silica wet masterbatch (WMB) technology is known to be suitable for manufacturing silica filled compounds that have high silica content and high dispersibility. Till now, the WMB study is focused on the natural rubber (NR) or emulsion styrene-butadiene rubber (ESBR) that does not have a silica-affinity functional group, and a study of NR or ESBR having a silica-affinity functional group is still not well known. Unlike the dry masterbatch technology, the WMB technology can solve the problems associated with the high Mooney viscosity when applied to silica-friendly rubber. However, a coagulant suitable for each functional group has not yet been determined. Therefore, in this study, different coagulant applied silica WMB was prepared by applying calcium chloride, sulfuric acid, acetic acid, and propionic acid by using a carboxyl group functionalized reversible addition fragmentation chain transfer ESBR. The evaluation of the WMB compounds revealed that the calcium chloride added WMB compound showed excellent silica dispersion, abrasion resistance, and rolling resistance.

Wave propagation and vibration of FG pipes conveying hot fluid

  • Zhang, Yi-Wen;She, Gui-Lin
    • Steel and Composite Structures
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    • 제42권3호
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    • pp.397-405
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    • 2022
  • The existing researches on the dynamics of the fluid-conveying pipes only focus on stability and vibration problems, and there is no literature report on the wave propagation of the fluid-conveying pipes. Therefore, the purpose of this paper is to explore the propagation characteristics of longitudinal and flexural waves in the fluid-conveying pipes. First, it is assumed that the material properties of the fluid-conveying pipes vary based on a power function of the thickness. In addition, it is assumed that the material properties of both the fluid and the pipes are closely depended on temperature. Using the Euler-Bernoulli beam equation and based on the linear theory, the motion equations considering the thermal-mechanical-fluid coupling is derived. Then, the exact expressions of phase velocity and group velocity of longitudinal waves and bending waves in the fluid-conveying pipes are obtained by using the eigenvalue method. In addition, we also studied the free vibration frequency characteristics of the fluid-conveying pipes. In the numerical analysis, we successively studied the influence of temperature, functional gradient index and liquid velocity on the wave propagation and vibration problems. It is found that the temperature and functional gradient exponent decrease the phase and group velocities, on the contrary, the liquid flow velocity increases the phase and group velocities. However, for vibration problems, temperature, functional gradient exponent parameter, and fluid velocity all reduce the natural frequency.

뇌졸중 환자의 마비쪽에 따른 골반의 기울임과 보행의 상관관계 분석 (Correlation Analysis of Pelvic Tilt and Gait according to the Paralytic Side of Stroke Patients)

  • Yong Seon, Lee;Jong-Hyuk, Yun
    • 한국운동역학회지
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    • 제32권4호
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    • pp.111-120
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    • 2022
  • Objective: This study investigated the effect of pelvic tiltng according to the paralytic side on gait in stroke patients during a 10 m functional movement timed up and go (TUG) test. Method: In this study, gait parameters were measured using a gait analyzer for 20 stroke patients and their gait was analyzed during a 10 m TUG test. For statistical analysis, an independent sample t-test were performed for age, height, and weight among general characteristics of subjects and homogeneity was tested by performing a chi-square test for gender, paralysis side, period of onset, and K-MMSE score. In order to understand the relationship between each variable, Pearson correlation analysis was performed on the variables. Results: First, the right-hand paralyzed group showed correlations in cadence and gait velocity in the up and down tilt of the pelvis, and the left-hand paralyzed group showed correlations in cadence and step length in the anterior and posterior tilt of the pelvis. Second, the tilt of the pelvis was correlated with the Sit to stand, walk forward, walk backwards, turn around at the end point, sit on a chair and the total TUG time in the right hemiplegic group compared to the left hemiplegic group. Conclusion: In this study, a significant correlation was confirmed as a result of gait analysis of right-handed stroke patients divided into a right paraplegic group and a left paraplegic group. In the future, it is suggested that treatment for improving gait of stroke patients should be treated differently for the right and left paralyzed side.

흰쥐 좌골신경 압좌손상 후 척수분절의 저강도 레이저 조사가 운동기능 회복에 미치는 영향 (Effects of Low Power Laser Irradiation on the Spinal Cord for the Functional Regeneration of Crushed Sciatic Nerve in Rats)

  • 김석범;김동현;송주민;남기원;권영실;김진상
    • The Journal of Korean Physical Therapy
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    • 제13권3호
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    • pp.569-578
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    • 2001
  • The purpose of the present study was to examine the functional recovery of the crushed sciatic nerve of rats after low-power laser irradiation applied to the corresponding segments of the spinal cord. After a crushed injury on the left sciatic nerve in rats. low-power laser irradiation was applied transcutaneously to corresponding segments of the spinal cord immediately after suture the wound by using 2000 mW, 2000Hz, 830 nm CaAIAs(Gallium-aluminum-arsenide) semiconductor diode laser. The laser treatment was performed with 10 minutes daily for 4 successive weeks. Functional recovery was evaluated per weekly following injury by sciatic function index(SFI),using data obtained by walking track analysis. For four weeks after crush injury, experimental group had significantly greater functional improvement than control group(${\alpha}$=0.05). In a experimental group, SFI was significantly increased for three weeks, but control group not increased for two weeks. This study suggests that low-power laser irradiation applied directly to the spinal cord can improve functional recovery of the crushed sciatic nerve in rats.

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Mutual Fund 수익률의 비정상 함수형 시그널을 위한 다해상도 클러스터 계층구조 (Multi-scale Cluster Hierarchy for Non-stationary Functional Signals of Mutual Fund Returns)

  • 김대룡;정욱
    • 경영과학
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    • 제24권2호
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    • pp.57-72
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    • 2007
  • Many Applications of scientific research have coupled with functional data signal clustering techniques to discover novel characteristics that can be used for the diagnoses of several issues. In this article we present an interpretable multi-scale cluster hierarchy framework for clustering functional data using its multi-aspect frequency information. The suggested method focuses on how to effectively select transformed features/variables in unsupervised manner so that finally reduce the data dimension and achieve the multi-purposed clustering. Specially, we apply our suggested method to mutual fund returns and make superior-performing funds group based on different aspects such as global patterns, seasonal variations, levels of noise, and their combinations. To promise our method producing a quality cluster hierarchy, we give some empirical results under the simulation study and a set of real life data. This research will contribute to financial market analysis and flexibly fit to other research fields with clustering purposes.