• 한국식품영양학회지
• /
• 제25권2호
• /
• pp.308-316
• /
• 2012

Proper skin care promotes good metabolism and the biological activity of skin, helps maintain the skin in a healthy and beautiful state when combined with nutritional nourishment. Health functional foods are being used for the purpose of enhancing efficient skin care. Health functional foods related to skin care maintain the epidermis, dermal fibroblast layer and subcutaneous tissue that form the skin. Efficient functional foods alleviate the signs of endogenous aging that come with getting older and exogenous aging caused by sunlight. Even though the field of skin care related to health functional foods has received less attention and been the subject of less research compared to functional cosmetics which are developing widely, this area of skin care that maintains and improves the layer of dermal fibroblast through the intake of food, is expected to progress with the commercialization of products in many fields when the related technical research development is galvanized and the related patents are applied for. Research into health functional foods related to skin care in Korea started rather late in comparison to other advanced countries where patents for relevant techniques have been applied for since 1990's together with research conducted on how they might be used for practical purposes. This study used the key words 'skin care, health functional food' to search for Korean patents that have been applied for at the Korean Intellectual Property Office from 1983 to 2011 using the KIPRIS database, in order to help researchers in the related fields by organizing the patented formulas for health functional foods for skin care which have gained attention recently. According to the number of registrations in each industry field, the total number of patents was 1,120 we screened the major patents among them, the field with the largest number was food foodstuff non-alcoholic beverage and preparation or treatment(A23L) with 135, then natural plant medicine & medical supplies and cosmetics(A61K) with 112, microorganisms or enzymes(C12N) with 63, heterocyclic compounds(C07D) with 44, horticulture or cultivation of sea weeds, forestry(A01G) 16 times, listed from the highest to the lowest number of applications. It has been revealed that food, foodstuff, non-alcoholic beverage and preparation or treatment(A23L) was the industry field where the most patents for health functional foods related to skin care were registered.

• 한국의류산업학회지
• /
• 제13권1호
• /
• pp.1-6
• /
• 2011

Design patent is a type of industrial design right that is granted on the ornamental design of a functional item. We analyzed domestic design patents that were applied from 1965 until 2008, to the field of functional clothing. Since the year 2000 the number of design patents of functional clothing progressively increased. Design patents applied to the functional clothing field includes sport wear (47%), working clothes (34%), and leisure wear (19%). Design development of the sports wear from the latter half of 1990's has shown a continuously increasing tendency. The most patent applications belonged to the companies(51.4%), followed by individual applicants (46.6%), and the universities or laboratories had the least number of applications (2.0%). In case of working clothes or the leisure wear, the number of design applications focusing on the functional characteristic is higher than that of aesthetic characteristic, however, the number of design applications focusing on the aesthetic characteristic is higher in sportswear.

• Journal of Magnetics
• /
• 제14권1호
• /
• pp.42-46
• /
• 2009

The measurement of external magnetic field orientation using Giant Magneto Impedance (GMI) sensors has been performed. A soft magnetic alloy of $Co_{30}Fe_{34}Ni_{36}$ was electroplated on a Si wafer with a CoFeNi seed layer. V-shaped microwire patterns were formed using a conventional photolithography process. An external magnetic field was generated by a rectangular AlNiCo permanent magnet. The reference direction was defined as the external magnetic field direction oriented in the middle of 2 GMI devices. As the orientation of the magnetic field deviated from the reference direction, variation in the field component along each device introduced voltage changes. It was found that, by taking the voltage difference between the left and right arms of the Vshaped device, the nonlinearity of each device could be significantly reduced. The fabricated angle sensor had a linear range of approximately $70^{\circ}$ and an overall sensitivity of approximately 10 mV.

• 호남수학학술지
• /
• 제24권1호
• /
• pp.121-130
• /
• 2002

In this paper we prove a functional central limit theorem for a field $\{X_{\underline{j}}:{\underline{j}}{\in}Z_+^d\}$ of nonstationary associated random variables with $EX{\underline{j}}=0,\;E{\mid}X_{\underline{j}}{\mid}^{r+{\delta}}<{\infty}$ for some $r>2,\;{\delta}>0$and $u(n)=O(n^{-{\nu}})$ for some ${\nu}>0$, where $u(n):=sup_{{\underline{i}}{\in}Z_+^d{\underline{j}}:{\mid}{\underline{j}}-{\underline{i}}{\mid}{\geq}n}{\sum}cov(X_{\underline{i}},\;X_{\underline{j}}),\;{\mid}{\underline{x}}{\mid}=max({\mid}x_1{\mid},{\cdots},{\mid}x_d{\mid})\;for\;{\underline{x}}{\in}{\mathbb{R}}^d$. Our investigation implies and analogous result in the case associated random measure.

• 대한의용생체공학회:의공학회지
• /
• 제17권4호
• /
• pp.525-534
• /
• 1996

We have developed a fast steady state free precession interferometry (SSFPI) technique which is useful for the fMRl (functional Magnetic Resonance Imaging). As is known, SSFP sequence with a suitable adjustment of Vadient (readeut) allows us to measure precession angle 6 which in tw relates to the field inhomogeneity. Combining the two pulses (known as FID and Echo) in FADE (Fast Acquisition Double Echo) sequence, for example, one can obtain the interference term which is directly related to the precession angle It has been known that a fast high resolution magnetic field mapping is possible by use of the modified FADE sequence or SSFPI, and we have attempted to use the SSFPI technique for the susceptibility-induced fMRl. When the method is applied to the susceptibility effect based functional magnetic resonance imaging (fMRl), it was found that the direct susceptibility effect measurement was possible without perturbations such as the backgrounds and inflow effect. In this paper, simulation results and experimental results obtained with 2.0 Tesla MRI system are presented.

• 대한수학회논문집
• /
• 제12권2호
• /
• pp.411-418
• /
• 1997

In this note we prove a functional central limit theorem for nonstationary linearly positive quadrant dependent random fields. We extend it to the case of random measures.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2011년도 제40회 동계학술대회 초록집
• /
• pp.482-483
• /
• 2011

Graphene is a good candidate for the future nano-electronic materials because it has excellent conductivity, mobility, transparency, flexibility and others. Until now, most graphene researches are focused on the nano electronic device applications, however, biological application of graphene has been relatively less reported. We have fabricated a deoxyribonucleic acid (DNA) conjugated graphene field-effect transistor (FET) and measured the electrical transport characteristics. We have used graphene sheets grown on Ni substrates by chemical vapour deposition. The Raman spectra of graphene sheets indicate high quality and only a few number of layers. The synthesized graphene is transferred on top of the substrate with pre-patterned electrodes by the floating-and-scooping method [1]. Then we applied adhesive tapes on the surface of the graphene to define graphene flakes of a few micron sizes near the electrodes. The current-voltage characteristic of the graphene layer before stripping shows linear zero gate bias conductance and no gate operation. After stripping, the zero gate bias conductance of the device is reduced and clear gate operation is observed. The change of FET characteristics before and after stripping is due to the formation of a micron size graphene flake. After combined with 30 base pairs single-stranded poly(dT) DNA molecules, the conductance and gate operation of the graphene flake FETs become slightly smaller than that of the pristine ones. It is considered that DNA is to be stably binding to the graphene layer due to the ${\pi}-{\pi}$ stacking interaction between nucleic bases and the surface of graphene. And this binding can modulate the electrical transport properties of graphene FETs. We also calculate the field-effect mobility of pristine and DNA conjugated graphene FET devices.

• Journal of Magnetics
• /
• 제16권4호
• /
• pp.413-416
• /
• 2011

An array of FeCo nanotubes has been successfully fabricated in the pores of porous anodic aluminum oxide (AAO) templates by wetting templates method. The morphology and structure of the nanotube array were characterized by scanning electron microscopy, transmission electron microscopy and x-ray diffraction. The average diameter of the nanotubes was about 200 nm, and the length was more than 10 ${\mu}m$. Vibrating sample magnetometer and superconducting quantum interference device were used to investigate the magnetic properties of the nanotube array. Interaction between the nanotubes has been found to be demagnetizing as expected and the switching field distribution is broad.

• 대한안전경영과학회지
• /
• 제19권3호
• /
• pp.109-115
• /
• 2017

In order to increase the productivity of the logistics center and transportation, we try to articulate the priority ranking factors of the productivity influenced by the personality of the field workers (logistics center workers) and functional workers (drivers) via the AHP technique Individual personality was studied by applying the Big 5 model of psychological factors (openness, Conscientiousness, extroversion, Agreeableness, neuroticism). In this paper, extraversion was critically analyzed as a priority factor. A trait of extroversion is a strongly active and individual personality. In this study, the field workers are logistics center workers and the functional workers are drivers. They are interactively influenced in the In & Out operation. For example, when it comes to 'up and down work' and 'inspection work', the functional workers perform 'up and down work' and 'delivery work' and the field workers perform 'inspection work'. Stressing on the respective work has an affect on work productivity. Inspection workforce has something to do with inventory management. Functional workforce affects the delivery workforce. Delivery work is positively correlated with customer satisfaction. Nevertheless, as a result of research, extrovert personality that has something to do with an energetic activity would not affect on the implementation of their operation. In addition, personal extraversion of workers and drivers in the warehouse can have a significant impact on job commitment and productivity improvement.

• Investigative Magnetic Resonance Imaging
• /
• 제1권1호
• /
• pp.114-118
• /
• 1997

목적: 기능적 MR 영상은 외부자극에 따라, 이에 상응하는 특정한 뇌피질 부위의 혈류량의 변화를 신호강도의 차이로 나타내는 방법이다. 시각피질에 대한 기능적 MR은 환자가 광자극을 응시함으로써 수행될 수 있는 것으로, 이의 수행에는 적절한 형태의 광자극원이 필수적이다. 이에 저자는 광자극원의 크기가 시각피질 활성화에 영향을 미칠 수 있는지 알아보기 위하여 본 연구를 하였다. 대상 및 방법: 정상적인 시력을 가진 자원자 5명을 대상으로 시각활성화 기능적 MR을 시행하였다. 광자극원은 $11{\times}8cm$ 크기의 기판에 적색 LED(light-emitting diodes) 39개를 박고 직류전원을 사용하도록 만들었다. 이를 크기에 따라 full field, half field 및 focal central field의 3가지로 구분하고 8Hz로 점멸하였다. EPI 기법으로 6회의 광자극 기간과 6회의 휴식기간을 번갈아 3차례 시행하여 총 36회의 검사를 하고, Z-score로 통계처리하였다. 이 때 얻은 활성화 영상을 같은 부위의 T1강조영상에 결합시켰다. 각 경우에서 시각피질에서 활성화된 pixel의 수를 full field, half field 및 focal central field에서 얻어진 pixel 수의 합으로 나누어 활성화지수를 구하였다. 이 활성화지수를 토대로 광원크기와의 관계를 분석하였다. 결과: Full field로 자극을 주었을 때 시각피질의 평균 신호강도의 증가는 약 9.6%였다. 4명에서 활성화지수는 full field, half field, focal central field의 순으로 감소하였으며, 나머지 1명에서는 half field 시의 값이 full field 시의 값보다 컸다. 광원크기에 따른 활성화지수의 범위는 full field 43-73%(평균 55%), half field 22-40%(평균 32%), focal central field 5-24%(평균 13%)였다. 결론: 기능적 MR영상을 이용하여 시각피질의 활성화를 용이하게 확인할 수 있었으며 광자극원의 크기에 따라 증가되는 시각피질 활성화를 입증할 수 있었다.