• Journal of Biomedical Engineering Research
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• v.27 no.3
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• pp.110-116
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• 2006

Finite element method (FEM) provides several advantages over other numerical methods such as boundary element method, since it allows truly volumetric analysis and incorporation of realistic electrical conductivity values. Finite element mesh generation is the first requirement in such in FEM to represent the volumetric domain of interest with numerous finite elements accurately. However, conventional mesh generators and approaches offered by commercial packages do not generate meshes that are content-adaptive to the contents of given images. In this paper, we present software that has been implemented to generate content-adaptive finite element meshes (cMESHes) based on the contents of MR images. The software offers various computational tools for cMESH generation from multi-slice MR images. The software named as the Content-adaptive FE Mesh Generation Toolbox runs under the commercially available technical computation software called Matlab. The major routines in the toolbox include anisotropic filtering of MR images, feature map generation, content-adaptive node generation, Delaunay tessellation, and MRI segmentation for the head conductivity modeling. The presented tools should be useful to researchers who wish to generate efficient mesh models from a set of MR images. The toolbox is available upon request made to the Functional and Metabolic Imaging Center or Bio-imaging Laboratory at Kyung Hee University in Korea.

• Structural Engineering and Mechanics
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• v.9 no.6
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• pp.519-540
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• 2000

In this study, a new functional based on the Reissner theory, for thick plates on a Winkler foundation is obtained. This functional has geometric and dynamic boundary conditions. In deriving the new functional, the $G{\hat{a}}teaux$ differential is used. This functional which is in polar coordinates is also transformable into the classical potential energy equation. Bending and torsional moments, transverse shear forces, rotations and displacements are the basic unknowns of the functional. Two different sectorial elements are developed with $3{\times}8$ degrees of freedom (SEC24) and $4{\times}8$ degrees of freedom (SEC32). The accuracy of the SEC24 and SEC32 elements together are verified by applying the method to some problems taken from literature.

• Genomics & Informatics
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• v.5 no.4
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• pp.188-193
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• 2007

The Functional Element SNPs Database (FESD) categorizes functional elements in human genic regions and provides a set of single nucleotide polymorphisms (SNPs) located within each area. Users may select a set of SNPs in specific functional elements with haplotype information and obtain flanking sequences for genotyping. Our previous version of FESD has been improved in several ways. We regenerated all the data in FESD II from recently updated source data such as HapMap, UCSC GoldenPath, dbSNP, OMIM, and $TRANSFAC^{(R)}$. Users can obtain information about tagSNPs and simulate LD blocks for each gene from four ethnicities in the HapMap project on the fly. FESD II employs a Java/JSP web interface for better platform portability and higher speed than PHP in the previous version. As a result, FESD II provides its users with more powerful information about functional element SNPs of human ethnicities.

• Proceedings of the KIEE Conference
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• 1987.07b
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• pp.1467-1470
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• 1987

This paper proposes a functional simulation algorithm which decrease the internal memory space and run time in simulation of VLSI. Flip-flop, register, ram, rom, ic and fun are described as functional elements in the simulator. Especially icf is made as new functional element by combining the gate and the functional element, therefore icf is used efficiently in simulation of VLSI. The proposed algorithm is implemented on PC-AT(MS-DOS) in by Prolog-1.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2008.04a
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• pp.33-38
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• 2008

For the propagation of elastic waves in unbounded domains, absorbing boundary conditions at the fictitious numerical boundaries have been proposed. Paraxial boundary conditions(PBCs) which are kinds of absorbing boundary conditions based on paraxial approximations of the scalar and elastic wave equations not only lead to well-posed problem but also are stable and computationally inexpensive. But the complex mathematical forms of PBCs with partial derivatives complicate the application of those to finite element analysis. In this paper a penalty functional is newly proposed for applying PBCs into finite element analysis and the existence and uniqueness of the extremum of the proposed functional is demonstrated. The numerical verification of the efficiency is carried out through comparing PBCs with a viscous boundary condition.

• Advances in Computational Design
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• v.5 no.2
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• pp.147-175
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• 2020

To achieve appropriate stresses, two new rectangular elements are presented in this study. For reaching this aim, a complementary energy functional is used within an element for the analysis of plane problems. In this energy form, the Airy stress function will be used as a functional variable. Besides, some basic analytical solutions are found for the stress functions. These trial functions are matched with each element number of degrees of freedom, which leads to a number of equations with the anonymous constants. Subsequently, according to the principle of minimum complementary energy, the unknown constants can be expressed in terms of displacements. This system can be rewritten in terms of the nodal displacement. In this way, two new hybrid-rectangular triangular elements are formulated, which have 16 and 40 degrees of freedom. To validate the outcomes, extensive numerical studies are performed. All findings clearly demonstrate accuracies of structural displacements, as well as, stresses.

• Computational Structural Engineering
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• v.8 no.3
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• pp.79-89
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• 1995

Two-element plate concept is incorporated into the buckling problem in order to simplify the nonlinear distribution of stress through the thickness of plate. Finite element formulations and programs based upon the Reissner functional and the modified Reissner functional using two-element plate concept are developed for buckling analysis of plates under axial compression. The two programs have been applied to obtain the linear elastic buckling behavior of axially compressed flat plates. Excellent agreement of linear elastic-solution results with exact or approximate solutions of other authors for the same boundary conditions proves the validity of the finite element method using two-element plate theory.

• Journal of the Korean Magnetics Society
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• v.1 no.2
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• pp.79-84
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• 1991

A variational approach employing localized functional is presented to solve alternating magnetic field problems with open boundary. The functional used in the approach consists of the domain integral of finite element region only and the boundary integral of the interfacial boundary between the finite and infinite element regions. The boundary integral is obtained by transforming the infinite domain integral for the infinite element region into the interfacial boundary integral. The proposed algorithm is then applied to a simple two-dimensional problem where the analytic solutions are available. It is shown that the algorithm makes it possible to yield good agreements between the numerical and analytic solutions. and that it requires less computer storage memory and computation time than the conventional finite element method due to the reduction of the computing region.

• Korean Journal of Microbiology
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• v.31 no.3
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• pp.208-213
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• 1993

The structural and functional roles of IGS element of T4 td intron in thymidylate synthase activity in vivo were investigated Site-directed mutagenesis was employed to crete mutations of IGS element of T4 td intron, When a U-G pari was changed to a U-C pari in the 5' splice site of P1 stem of td intron, the activity of thymidylate synthase was completely abolished whereas the wild type retained the normal activity of enzyme. When U at 12 position within IGS element was changed to C, the activity of thymidylate synthase was approximately 32% of that of the wild type. Comparison of enzyme activities suggests that IGS element within P1 structure is an essential requirement for splicing of td gene in vivo.

• Bulletin of the Korean Mathematical Society
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• v.54 no.6
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• pp.2165-2182
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• 2017

Let G be a group and $\mathbb{C}$ the field of complex numbers. Suppose ${\sigma}:G{\rightarrow}G$ is an endomorphism satisfying ${{\sigma}}({{\sigma}}(x))=x$ for all x in G. In this paper, we first determine the central solution, f : G or $G{\times}G{\rightarrow}\mathbb{C}$, of the functional equation $f(xy)+f({\sigma}(y)x)=2f(x)+2f(y)$ for all $x,y{\in}G$, which is a variant of the quadratic functional equation. Using the central solution of this functional equation, we determine the general solution of the functional equation f(pr, qs) + f(sp, rq) = 2f(p, q) + 2f(r, s) for all $p,q,r,s{\in}G$, which is a variant of the equation f(pr, qs) + f(ps, qr) = 2f(p, q) + 2f(r, s) studied by Chung, Kannappan, Ng and Sahoo in [3] (see also [16]). Finally, we determine the solutions of this equation on the free groups generated by one element, the cyclic groups of order m, the symmetric groups of order m, and the dihedral groups of order 2m for $m{\geq}2$.